[go: up one dir, main page]

BRPI0911925B8 - Método para detectar um câncer - Google Patents

Método para detectar um câncer

Info

Publication number
BRPI0911925B8
BRPI0911925B8 BRPI0911925A BRPI0911925A BRPI0911925B8 BR PI0911925 B8 BRPI0911925 B8 BR PI0911925B8 BR PI0911925 A BRPI0911925 A BR PI0911925A BR PI0911925 A BRPI0911925 A BR PI0911925A BR PI0911925 B8 BRPI0911925 B8 BR PI0911925B8
Authority
BR
Brazil
Prior art keywords
cancer
detecting
fragment
goat protein
protein
Prior art date
Application number
BRPI0911925A
Other languages
English (en)
Inventor
Fumiyoshi Okano
Kana Suzuki
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of BRPI0911925A2 publication Critical patent/BRPI0911925A2/pt
Publication of BRPI0911925B1 publication Critical patent/BRPI0911925B1/pt
Publication of BRPI0911925B8 publication Critical patent/BRPI0911925B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/57515
    • G01N33/575
    • G01N33/57557
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

método para detectar um câncer e reagentes para detectar um câncer a presente invenção refere-se a um método para detectar câncer, que compreende medir a expressão de um polipeptídeo que tem uma reatividade de ligação a um anticorpo contra uma proteína caprina-1 que tem uma sequência de aminoácido mostrada em qualquer uma das seq id nos: 2 a 30 na listagem de sequências através de uma reação antígeno-anticorpo em uma amostra separada de um organismo vivo e um reagente para detectar um câncer que compreende a proteína caprina-1 ou um fragmento deste, um anticorpo contra a proteína caprina-1 ou um fragmento deste, ou um polinucleotídeo que codifica a proteína caprina-1 ou um fragmento deste.
BRPI0911925A 2008-08-05 2009-08-05 Método para detectar um câncer BRPI0911925B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008202320 2008-08-05
JP1008-202320 2008-08-05
PCT/JP2009/063883 WO2010016527A1 (ja) 2008-08-05 2009-08-05 癌の検出方法

Publications (3)

Publication Number Publication Date
BRPI0911925A2 BRPI0911925A2 (pt) 2016-09-20
BRPI0911925B1 BRPI0911925B1 (pt) 2024-01-30
BRPI0911925B8 true BRPI0911925B8 (pt) 2024-02-06

Family

ID=41663744

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911925A BRPI0911925B8 (pt) 2008-08-05 2009-08-05 Método para detectar um câncer

Country Status (16)

Country Link
US (1) US11137401B2 (pt)
EP (2) EP2325648B1 (pt)
JP (2) JP5644110B2 (pt)
KR (2) KR101606779B1 (pt)
CN (1) CN102171570B (pt)
AU (2) AU2009278387B2 (pt)
BR (1) BRPI0911925B8 (pt)
CA (1) CA2732980C (pt)
DK (2) DK2733492T3 (pt)
ES (2) ES2471379T3 (pt)
HU (1) HUE027332T2 (pt)
MX (2) MX337991B (pt)
PL (2) PL2325648T3 (pt)
PT (1) PT2325648E (pt)
RU (2) RU2519089C2 (pt)
WO (1) WO2010016527A1 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102170907A (zh) * 2008-08-05 2011-08-31 东丽株式会社 用于治疗和预防癌症的药物组合物
BRPI0911925B8 (pt) 2008-08-05 2024-02-06 Toray Industries Método para detectar um câncer
JP5742714B2 (ja) 2010-02-04 2015-07-01 東レ株式会社 癌の治療及び/又は予防用医薬組成物
MX2012008991A (es) * 2010-02-04 2012-09-07 Toray Industries Medicamento para tratar y/o prevenir el cancer.
PL2532743T3 (pl) * 2010-02-04 2015-09-30 Toray Industries Kompozycja farmaceutyczna do leczenia i/lub zapobiegania raka
EP2532366B1 (en) * 2010-02-04 2016-09-07 Toray Industries, Inc. Pharmaceutical composition for treating and/or preventing cancer
JP5845899B2 (ja) * 2010-02-04 2016-01-20 東レ株式会社 癌の治療及び/又は予防用医薬組成物
ES2583777T3 (es) * 2010-02-04 2016-09-22 Toray Industries, Inc. Composición farmacéutica que comprende anticuerpos anti CAPRIN-1 para el tratamiento y/o la prevención del cáncer
ES2634249T3 (es) * 2011-08-04 2017-09-27 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la profilaxis del cáncer
DK2740489T3 (en) * 2011-08-04 2017-01-16 Toray Industries Pharmaceutical composition for the treatment and / or prevention of pancreatic cancer
RU2610428C2 (ru) 2011-08-04 2017-02-10 Торэй Индастриз, Инк. Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли
EP2741085B1 (en) * 2011-08-04 2017-04-05 Toray Industries, Inc. Method for detecting pancreatic cancer
WO2013018883A1 (ja) * 2011-08-04 2013-02-07 東レ株式会社 癌の治療及び/又は予防用医薬組成物
TR201802089T4 (tr) * 2011-08-04 2018-03-21 Toray Industries Kanserin tedavisi ve/veya önlenmesi amacına yönelik ilaç bileşimi.
BR112014002618B1 (pt) * 2011-08-04 2022-09-20 Toray Industries, Inc Anticorpo, composição farmacêutica, dna, uso de um anticorpo e uso de uma composição farmacêutica
IN2014KN01715A (pt) 2012-02-21 2015-10-23 Toray Industries
HUE045461T2 (hu) * 2012-02-21 2019-12-30 Toray Industries Gyógyászati készítmény rák kezelésére
WO2013125636A1 (ja) * 2012-02-21 2013-08-29 東レ株式会社 癌の治療及び/又は予防用医薬組成物
CN104114581B (zh) * 2012-02-21 2018-11-30 东丽株式会社 癌的治疗和/或预防用药物组合物
ES2656620T3 (es) * 2012-03-30 2018-02-27 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la prevención del cáncer de hígado
JP6107655B2 (ja) * 2012-03-30 2017-04-05 東レ株式会社 胆嚢癌の治療及び/又は予防用医薬組成物
JP6244912B2 (ja) * 2012-07-19 2017-12-13 東レ株式会社 癌の検出方法
HUE043162T2 (hu) 2012-07-19 2019-08-28 Toray Industries Eljárás rák detektálására
TR201819812T4 (tr) 2013-08-09 2019-01-21 Toray Industries Kanserin Tedavisi Ve/Veya Önlenmesi Amacına Yönelik Farmasötik Bileşim
WO2016084912A1 (ja) * 2014-11-27 2016-06-02 公立大学法人横浜市立大学 卵巣明細胞腺癌の検査方法及び検査薬
RU2611896C1 (ru) * 2016-03-10 2017-03-01 Федеральное государственное бюджетное учреждение здравоохранения Клиническая больница N 122 имени Л.Г. Соколова Федерального медико-биологического агентства (ФГБУЗ КБ N 122 им. Л.Г. Соколова ФМБА России) Способ диагностики лейомиомы мочевого пузыря
TWI782000B (zh) * 2017-03-30 2022-11-01 日商第一三共股份有限公司 抗gpr20抗體、其製造方法及其應用
WO2018187512A1 (en) * 2017-04-04 2018-10-11 Corvus Pharmaceuticals, Inc. Methods for treating cd73hi tumors
RU2677064C1 (ru) * 2017-10-13 2019-01-15 Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ определения границ резекции при лечении остеосаркомы
JP6875451B2 (ja) * 2018-09-26 2021-05-26 株式会社レナテック 犬のがんリスク評価方法及びがんリスク評価システム
WO2020067261A1 (ja) * 2018-09-26 2020-04-02 株式会社レナテック 犬のがんリスク評価方法及びがんリスク評価システム
KR20250166224A (ko) 2023-03-28 2025-11-27 도레이 카부시키가이샤 세포막 단백질을 검출하는 방법
JPWO2024204685A1 (pt) 2023-03-31 2024-10-03

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9102074D0 (sv) 1991-07-03 1991-07-03 Kabi Pharmacia Ab Tomour antigen specific antibody
ES2336976T3 (es) 1994-09-19 2010-04-19 Ricardo J. Moro Deteccion de cancer.
US5698396A (en) 1995-06-07 1997-12-16 Ludwig Institute For Cancer Research Method for identifying auto-immunoreactive substances from a subject
US20030118599A1 (en) * 1999-04-02 2003-06-26 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
TW200532020A (en) 1998-07-14 2005-10-01 Corixa Corp Compositions and methods for therapy and diagnosis of prostate cancer
RU2234942C2 (ru) * 1998-07-14 2004-08-27 Корикса Корпорейшн Выделенный опухолевый полипептид предстательной железы и кодирующий его полинуклеотид
GB9815909D0 (en) 1998-07-21 1998-09-16 Btg Int Ltd Antibody preparation
US6969518B2 (en) 1998-12-28 2005-11-29 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
WO2000052204A2 (en) * 1999-02-22 2000-09-08 Orntoft Torben F Gene expression in bladder tumors
US6444425B1 (en) 1999-04-02 2002-09-03 Corixa Corporation Compounds for therapy and diagnosis of lung cancer and methods for their use
WO2000060077A2 (en) 1999-04-02 2000-10-12 Corixa Corporation Compounds for therapy and diagnosis of lung cancer and methods for their use
DK1176195T3 (da) 1999-04-09 2013-06-24 Kyowa Hakko Kirin Co Ltd Fremgangsmåde til at kontrollere aktiviteten af immunologisk funktionelt molekyle
US6949245B1 (en) 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
CA2388822A1 (en) * 1999-10-29 2001-05-10 Human Genome Sciences, Inc. 27 human secreted proteins
CA2404233A1 (en) * 2000-03-29 2001-10-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US7919467B2 (en) 2000-12-04 2011-04-05 Immunotope, Inc. Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US7408041B2 (en) 2000-12-08 2008-08-05 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US20040029114A1 (en) * 2001-01-24 2004-02-12 Eos Technology, Inc. Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer
RU2306952C2 (ru) 2001-01-31 2007-09-27 Байоджен Айдек Инк. Лечение в-клеточных злокачественных опухолей с использованием комбинации применений, связанных с антителами, уменьшающими количество b-клеток, и с иммуномодулирующими антителами
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
WO2002083070A2 (en) 2001-04-10 2002-10-24 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
WO2002092001A2 (en) 2001-05-11 2002-11-21 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US20030190640A1 (en) * 2001-05-31 2003-10-09 Mary Faris Genes expressed in prostate cancer
IL159894A0 (en) 2001-07-17 2004-06-20 Res Dev Foundation Therapeutic agents comprising pro-apoptotic proteins
RU2319709C2 (ru) 2001-07-17 2008-03-20 Рисерч Дивелопмент Фаундейшн Терапевтические агенты, содержащие проапоптозные белки
US20040142325A1 (en) 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
EP1575480A4 (en) 2002-02-22 2008-08-06 Genentech Inc COMPOSITIONS AND METHODS OF TREATING IMMUNE-INFLAMMATORY DISEASES
US20050003390A1 (en) * 2002-05-17 2005-01-06 Axenovich Sergey A. Targets for controlling cellular growth and for diagnostic methods
US20040126379A1 (en) 2002-08-21 2004-07-01 Boehringer Ingelheim International Gmbh Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents
US20060121029A1 (en) 2002-08-30 2006-06-08 Hiroshi Shiku Method and composition for regulating the activity of regulatory t cells
JP3869352B2 (ja) 2002-11-12 2007-01-17 日鉱金属株式会社 金属箔の熱量測定方法、表面特性の調整方法、レーザー穴開け方法又は熱量測定装置
WO2004047728A2 (en) 2002-11-26 2004-06-10 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2004076682A2 (en) * 2003-02-26 2004-09-10 Surromed, Inc. Targets for controlling cellular growth and for diagnostic methods
WO2004097051A2 (en) 2003-04-29 2004-11-11 Wyeth Methods for diagnosing aml and mds differential gene expression
EP1639090A4 (en) * 2003-06-09 2008-04-16 Univ Michigan COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
WO2005007830A2 (en) * 2003-07-14 2005-01-27 Mayo Foundation For Medical Education And Research Methods and compositions for diagnosis, staging and prognosis of prostate cancer
US20050032113A1 (en) 2003-07-17 2005-02-10 Mitsubishi Pharma Corporation Membrane protein library for proteome analysis and method for preparing same
WO2005116076A2 (en) 2004-01-26 2005-12-08 Debiovision Inc. Neoplasm-specific polypeptides and their uses
EP2332990A1 (en) 2004-03-19 2011-06-15 Imclone LLC Human anti-epidermal growth factor receptor antibody
WO2005100998A2 (en) 2004-04-16 2005-10-27 Europroteome Ag Membrane markers for use in cancer diagnosis and therapy
DE102004026135A1 (de) 2004-05-25 2006-01-05 Immatics Biotechnologies Gmbh An MHC-Moleküle bindende Tumor-assoziierte Peptide
WO2006002378A2 (en) * 2004-06-23 2006-01-05 Avalon Pharmaceuticals Determining cancer-linked genes and therapeutic targets using molecular cytogenetic methods
RU2391982C2 (ru) 2005-01-19 2010-06-20 Зериа Фармасьютикал Ко., Лтд. Противоопухолевое средство
PL1846030T3 (pl) 2005-01-21 2019-05-31 Genentech Inc Ustalone dawkowanie przeciwciał her
US7858324B2 (en) 2005-02-18 2010-12-28 Children's Medical Center Corporation Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin
CN101189516A (zh) * 2005-03-11 2008-05-28 赛弗吉生物系统公司 卵巢癌及子宫内膜癌的生物标记:抗菌蛋白(hepcidin)
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Herceptin(登録商標)補助療法
US8014957B2 (en) * 2005-12-15 2011-09-06 Fred Hutchinson Cancer Research Center Genes associated with progression and response in chronic myeloid leukemia and uses thereof
JP5490413B2 (ja) 2006-01-05 2014-05-14 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション 膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロrna発現異常
CA2642342A1 (en) 2006-02-14 2007-08-23 Dana-Farber Cancer Institute, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer
US20100015724A1 (en) * 2006-08-17 2010-01-21 Peter Hornbeck Lysine acetylation sites
US20080107668A1 (en) * 2006-08-30 2008-05-08 Immunotope, Inc. Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
WO2008031041A2 (en) 2006-09-07 2008-03-13 H. Lee Moffitt Cancer Center And Research Institute, Inc. Melanoma gene signature
WO2008059252A2 (en) 2006-11-15 2008-05-22 Oxford Biomedica (Uk) Limited Methods and composition fro t cell receptors which recognize 5t4 antigen
JP4958580B2 (ja) 2007-02-21 2012-06-20 鹿島建設株式会社 シールド機、シールド機とセグメントの間のクリアランス測定方法
PT2207037T (pt) 2007-10-25 2016-12-09 Toray Industries Método para a deteção de cancro
JP5663834B2 (ja) 2008-03-14 2015-02-04 東ソー株式会社 遺伝子組換え抗体の製造方法
NZ621433A (en) 2008-03-18 2015-10-30 Genentech Inc Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
CN102170907A (zh) 2008-08-05 2011-08-31 东丽株式会社 用于治疗和预防癌症的药物组合物
BRPI0911925B8 (pt) 2008-08-05 2024-02-06 Toray Industries Método para detectar um câncer
ES2619322T3 (es) 2008-08-05 2017-06-26 Toray Industries, Inc. Agente inductor de inmunidad
EP2467401B1 (en) 2009-08-19 2017-01-18 Merck Patent GmbH Antibodies for the detection of integrin complexes in ffpe material
MX2012003404A (es) 2009-09-22 2012-09-12 Volker Sandig Procedimiento para producir moleculas que contienen estructuras de glicano especializadas.
MX2012008991A (es) 2010-02-04 2012-09-07 Toray Industries Medicamento para tratar y/o prevenir el cancer.
PL2532743T3 (pl) 2010-02-04 2015-09-30 Toray Industries Kompozycja farmaceutyczna do leczenia i/lub zapobiegania raka
EP2532366B1 (en) 2010-02-04 2016-09-07 Toray Industries, Inc. Pharmaceutical composition for treating and/or preventing cancer
ES2583777T3 (es) 2010-02-04 2016-09-22 Toray Industries, Inc. Composición farmacéutica que comprende anticuerpos anti CAPRIN-1 para el tratamiento y/o la prevención del cáncer
JP5742714B2 (ja) 2010-02-04 2015-07-01 東レ株式会社 癌の治療及び/又は予防用医薬組成物
JP5845899B2 (ja) 2010-02-04 2016-01-20 東レ株式会社 癌の治療及び/又は予防用医薬組成物
WO2012005550A2 (ko) 2010-07-08 2012-01-12 강원대학교산학협력단 담낭암 치료용 약제학적 조성물 및 이를 이용한 담낭암의 성장, 전이 억제 및 치료 방법
CN103261224B (zh) 2010-07-26 2015-10-07 瑟维尔实验室 用于肝癌治疗的方法和组合物
RU2610428C2 (ru) 2011-08-04 2017-02-10 Торэй Индастриз, Инк. Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли
DK2740489T3 (en) 2011-08-04 2017-01-16 Toray Industries Pharmaceutical composition for the treatment and / or prevention of pancreatic cancer
WO2013018883A1 (ja) 2011-08-04 2013-02-07 東レ株式会社 癌の治療及び/又は予防用医薬組成物
BR112014002618B1 (pt) 2011-08-04 2022-09-20 Toray Industries, Inc Anticorpo, composição farmacêutica, dna, uso de um anticorpo e uso de uma composição farmacêutica
ES2634249T3 (es) 2011-08-04 2017-09-27 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la profilaxis del cáncer
EP2741085B1 (en) 2011-08-04 2017-04-05 Toray Industries, Inc. Method for detecting pancreatic cancer
TR201802089T4 (tr) 2011-08-04 2018-03-21 Toray Industries Kanserin tedavisi ve/veya önlenmesi amacına yönelik ilaç bileşimi.
CN104114581B (zh) 2012-02-21 2018-11-30 东丽株式会社 癌的治疗和/或预防用药物组合物
IN2014KN01715A (pt) 2012-02-21 2015-10-23 Toray Industries
WO2013125636A1 (ja) 2012-02-21 2013-08-29 東レ株式会社 癌の治療及び/又は予防用医薬組成物
HUE045461T2 (hu) 2012-02-21 2019-12-30 Toray Industries Gyógyászati készítmény rák kezelésére
ES2656620T3 (es) 2012-03-30 2018-02-27 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la prevención del cáncer de hígado
JP6107655B2 (ja) 2012-03-30 2017-04-05 東レ株式会社 胆嚢癌の治療及び/又は予防用医薬組成物
HUE043162T2 (hu) 2012-07-19 2019-08-28 Toray Industries Eljárás rák detektálására
JP6244912B2 (ja) 2012-07-19 2017-12-13 東レ株式会社 癌の検出方法
TR201819812T4 (tr) 2013-08-09 2019-01-21 Toray Industries Kanserin Tedavisi Ve/Veya Önlenmesi Amacına Yönelik Farmasötik Bileşim

Also Published As

Publication number Publication date
RU2671497C2 (ru) 2018-11-01
AU2015238877A1 (en) 2015-10-29
WO2010016527A1 (ja) 2010-02-11
KR20160039295A (ko) 2016-04-08
CA2732980C (en) 2017-08-15
AU2009278387B2 (en) 2015-07-09
EP2733492B1 (en) 2016-02-24
RU2011108258A (ru) 2012-09-10
KR20110052665A (ko) 2011-05-18
MX337991B (es) 2016-03-30
ES2471379T3 (es) 2014-06-26
JP5825386B2 (ja) 2015-12-02
CA2732980A1 (en) 2010-02-11
AU2009278387A1 (en) 2010-02-11
RU2519089C2 (ru) 2014-06-10
KR101606779B1 (ko) 2016-03-28
BRPI0911925B1 (pt) 2024-01-30
AU2015238877B2 (en) 2017-02-16
EP2733492A1 (en) 2014-05-21
CN102171570A (zh) 2011-08-31
RU2014111182A (ru) 2015-09-27
CN102171570B (zh) 2014-10-15
US11137401B2 (en) 2021-10-05
DK2325648T3 (da) 2014-07-28
PT2325648E (pt) 2014-06-24
EP2325648A1 (en) 2011-05-25
JPWO2010016527A1 (ja) 2012-01-26
MX2011001445A (es) 2011-04-05
JP5644110B2 (ja) 2014-12-24
US20110136121A1 (en) 2011-06-09
PL2325648T3 (pl) 2014-09-30
HUE027332T2 (en) 2016-09-28
DK2733492T3 (en) 2016-04-25
PL2733492T3 (pl) 2016-08-31
ES2570731T3 (es) 2016-05-20
JP2014134550A (ja) 2014-07-24
BRPI0911925A2 (pt) 2016-09-20
EP2325648B1 (en) 2014-04-23
EP2325648A4 (en) 2011-09-28

Similar Documents

Publication Publication Date Title
BRPI0911925B8 (pt) Método para detectar um câncer
EP3978927A2 (en) Methods and reagents for diagnosis of sars-cov-2 infection
CA2844033C (en) Method for detecting pancreatic cancer
MX2015000684A (es) Metodo para detectar cancer.
NZ603492A (en) Humanized anti-factor d antibodies and uses thereof
BR112015014833A2 (pt) anticorpo isolado ou fragmento de ligação de antígeno deste, ácido nucléico isolado, célula hospedeira, método de ensaiar uma amostra de tecido removido de um humano para expressão de pd-l1, estojo, e, composição de anticorpo que compreende uma mistura de moléculas do anticorpo
NZ600828A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ599105A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
BR112014020213A2 (pt) biomarcadores para o diagnóstico, o prognóstico, a avaliação e a estratificação de terapia de síncope
WO2008012362A3 (en) New protein isoforms and uses thereof
WO2010083252A3 (en) Ratio based biomarkers and methods of use thereof
EA201370063A1 (ru) Фосфолипидом рака
EA201001874A1 (ru) Способ диагностики злокачественных новообразований, экспрессирующих рецептор her2 или его укороченные варианты
EP2569635A4 (en) METHOD FOR DIAGNOSIS AND / OR TREATMENT OF ENZEPHALITIS OR EPILEPSY
MX2015000686A (es) Metodo para detectar cancer.
MX349996B (es) Metodos y composiciones para diagnostico y tratamiento del cancer.
WO2010046443A3 (en) Methods for detection and diagnosis of a bone or cartilage disorder
EP2074427A4 (en) Diagnostic biomolecule(s)
US20230417742A1 (en) Improved assays to detect nucleosome modifications using antibody-targeted enzyme digestion
JP2012501318A5 (pt)
MX2009010751A (es) Composiciones y metodos de deteccion.
NZ593392A (en) Biomarker for detecting bladder cancer
ATE468535T1 (de) Verwendung von nnmt als marker für lungenkrebs
PE20120592A1 (es) Metodo con biomarcadores para el seguimiento de un tratamiento
EP1930445A4 (en) KIT AND METHOD FOR DETECTING UROTHEL CARCINOMA

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/08/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REFERENTE A RPI 2769 DE 30/01/2024, QUANTO AO ITEM (30) PRIORIDADE UNIONISTA.