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BRPI0908229A2 - método para dispensar iontoforeticamente um corticoesteróide, derivado de corticoesteróide, pró-droga ou sal no olho de um paciente, kit para dispensar iontoforeticamente dexametasona no olho de um paciente, formulação de dexametasona, dispositivo para dispensar dexametasona, e, método para tratar uma doença oftálmica sensível a corticoesteróide em um mamífero. - Google Patents

método para dispensar iontoforeticamente um corticoesteróide, derivado de corticoesteróide, pró-droga ou sal no olho de um paciente, kit para dispensar iontoforeticamente dexametasona no olho de um paciente, formulação de dexametasona, dispositivo para dispensar dexametasona, e, método para tratar uma doença oftálmica sensível a corticoesteróide em um mamífero.

Info

Publication number
BRPI0908229A2
BRPI0908229A2 BRPI0908229A BRPI0908229A BRPI0908229A2 BR PI0908229 A2 BRPI0908229 A2 BR PI0908229A2 BR PI0908229 A BRPI0908229 A BR PI0908229A BR PI0908229 A BRPI0908229 A BR PI0908229A BR PI0908229 A2 BRPI0908229 A2 BR PI0908229A2
Authority
BR
Brazil
Prior art keywords
corticosteroid
dexamethasone
dispensing
iontophoretically
eye
Prior art date
Application number
BRPI0908229A
Other languages
English (en)
Inventor
Cook Gary
Jaffe Mike
Patane Mike
Calias Perry
Original Assignee
Eyegate Pharma S A S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eyegate Pharma S A S filed Critical Eyegate Pharma S A S
Publication of BRPI0908229A2 publication Critical patent/BRPI0908229A2/pt
Publication of BRPI0908229A8 publication Critical patent/BRPI0908229A8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Steroid Compounds (AREA)
BRPI0908229A 2008-02-25 2009-02-24 Uso de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste, kit e dispositivo para dispensar iontoforeticamente um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente para tratar um distúrbio ocular mediado por inflamação no referido paciente, e, formulação apropriada para dispensação iontoforética ocular de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente BRPI0908229A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3126708P 2008-02-25 2008-02-25
US4795008P 2008-04-25 2008-04-25
PCT/US2009/034977 WO2009108626A2 (en) 2008-02-25 2009-02-24 Enhanced delivery of a therapeutic to ocular tissues through iontophoresis

Publications (2)

Publication Number Publication Date
BRPI0908229A2 true BRPI0908229A2 (pt) 2017-06-13
BRPI0908229A8 BRPI0908229A8 (pt) 2017-10-10

Family

ID=41016683

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908229A BRPI0908229A8 (pt) 2008-02-25 2009-02-24 Uso de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste, kit e dispositivo para dispensar iontoforeticamente um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente para tratar um distúrbio ocular mediado por inflamação no referido paciente, e, formulação apropriada para dispensação iontoforética ocular de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente

Country Status (10)

Country Link
US (4) US20090306579A1 (pt)
EP (1) EP2249921B1 (pt)
JP (1) JP2011512903A (pt)
CN (1) CN101970042A (pt)
AU (1) AU2009219426B2 (pt)
BR (1) BRPI0908229A8 (pt)
CA (1) CA2716390C (pt)
IL (1) IL207014A0 (pt)
MX (1) MX2010009157A (pt)
WO (1) WO2009108626A2 (pt)

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WO2010078246A1 (en) * 2008-12-31 2010-07-08 Eyegate Pharma S.A.S. System and method for ocular iontophoresis with buffering
WO2012095877A1 (en) * 2011-01-12 2012-07-19 Sooft Italia Spa Corneal delivery of cross-linking agents by iontophoresis for the treatment of keratoconus and related ophthalmic compositions
WO2012162459A1 (en) * 2011-05-26 2012-11-29 Pepose Jay Device and method for administering eye medications
JP5463511B1 (ja) * 2013-05-13 2014-04-09 株式会社メディカル・アート イオン泳動式皮膚感染症治療装置
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015164626A2 (en) * 2014-04-23 2015-10-29 Seros Medical, Llc Vacuum-assisted drug delivery device and method
KR20170046146A (ko) * 2014-08-13 2017-04-28 더 존스 홉킨스 유니버시티 각막 동종이식 거부 및 신혈관 형성의 예방을 위한 글루코 코르티코이드-로딩된 나노입자
ES2874562T3 (es) * 2014-12-19 2021-11-05 Kemin Ind Inc Suministro intraocular de moléculas bioactivas mediante el uso de iontoforesis
EP3247452A4 (en) 2015-01-22 2018-11-14 Eyegate Pharmaceuticals, Inc. Iontophoretic contact lens
MY186271A (en) 2015-03-05 2021-07-01 Auckland Uniservices Ltd Ophthalmic compositions and methods of use therefor
WO2019089537A1 (en) 2017-10-31 2019-05-09 Tusker Medical, Inc. Systems, apparatus, and methods for delivery of therapeutic substance to nasal cavity
EP3883562A4 (en) 2018-11-21 2022-08-03 Tremeau Pharmaceuticals, Inc. PURIFIED FORMS OF ROFECOXIB AND METHODS OF MAKING AND USING
US11161833B1 (en) 2021-04-09 2021-11-02 Tremeau Pharmaceuticals, Inc. Deuterated etoricoxib, methods of manufacture, and use thereof

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Also Published As

Publication number Publication date
AU2009219426B2 (en) 2015-12-03
AU2009219426A1 (en) 2009-09-03
BRPI0908229A8 (pt) 2017-10-10
US20090306579A1 (en) 2009-12-10
MX2010009157A (es) 2010-09-24
US20140046242A1 (en) 2014-02-13
US10376463B2 (en) 2019-08-13
WO2009108626A2 (en) 2009-09-03
JP2011512903A (ja) 2011-04-28
EP2249921B1 (en) 2020-06-17
US9820935B2 (en) 2017-11-21
CN101970042A (zh) 2011-02-09
US20120283231A1 (en) 2012-11-08
IL207014A0 (en) 2010-12-30
CA2716390C (en) 2016-08-23
US20160263024A1 (en) 2016-09-15
EP2249921A4 (en) 2015-02-11
US9149525B2 (en) 2015-10-06
EP2249921A2 (en) 2010-11-17
CA2716390A1 (en) 2009-09-03
WO2009108626A3 (en) 2010-01-07

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: EYEGATE PHARMACEUTICALS, INC. (US)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: A61N 1/30

Ipc: A61N 1/04 (1968.09), A61K 9/00 (1968.09), A61K 31/

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61N 1/04 , A61K 9/00 , A61K 31/573 , A61N 1/30 , A61K 41/00 , A61F 9/00

Ipc: A61K 31/573 (2006.01), A61K 9/00 (2006.01), A61N 1

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL