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BRPI0906045A2 - "composição farmacêutica para administração nasal" - Google Patents

"composição farmacêutica para administração nasal"

Info

Publication number
BRPI0906045A2
BRPI0906045A2 BRPI0906045-6A BRPI0906045A BRPI0906045A2 BR PI0906045 A2 BRPI0906045 A2 BR PI0906045A2 BR PI0906045 A BRPI0906045 A BR PI0906045A BR PI0906045 A2 BRPI0906045 A2 BR PI0906045A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
nasal administration
nasal
administration
pharmaceutical
Prior art date
Application number
BRPI0906045-6A
Other languages
English (en)
Inventor
Mariko Morishita
Kozo Takayama
Nobuo Ida
Reiji Nishio
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of BRPI0906045A2 publication Critical patent/BRPI0906045A2/pt
Publication of BRPI0906045B1 publication Critical patent/BRPI0906045B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • C07K14/43581Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies from Drosophila

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BRPI0906045-6A 2008-02-28 2009-02-27 Composição farmacêutica para administração nasal BRPI0906045B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008-048300 2008-02-28
JP2008048300 2008-02-28
PCT/JP2009/053648 WO2009107766A1 (ja) 2008-02-28 2009-02-27 経鼻投与用医薬組成物

Publications (2)

Publication Number Publication Date
BRPI0906045A2 true BRPI0906045A2 (pt) 2015-07-07
BRPI0906045B1 BRPI0906045B1 (pt) 2022-01-25

Family

ID=41016151

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906045-6A BRPI0906045B1 (pt) 2008-02-28 2009-02-27 Composição farmacêutica para administração nasal

Country Status (13)

Country Link
US (1) US8895503B2 (pt)
EP (1) EP2253326B1 (pt)
JP (2) JP4711013B2 (pt)
KR (1) KR101585046B1 (pt)
CN (1) CN101959532B (pt)
AU (1) AU2009218060B2 (pt)
BR (1) BRPI0906045B1 (pt)
CA (1) CA2716565C (pt)
ES (1) ES2671024T3 (pt)
MX (1) MX2010009148A (pt)
PL (1) PL2253326T3 (pt)
RU (1) RU2470666C2 (pt)
WO (1) WO2009107766A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2433953T3 (pl) * 2009-05-20 2015-12-31 Toray Industries Peptydy o zdolności przenikania przez błonę komórkową
JP2014502953A (ja) * 2010-08-16 2014-02-06 ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク 細胞透過性治療薬の鼻腔内送達
CN112313749B (zh) * 2018-04-13 2025-02-07 香港理工大学 使用肽的数据存储
CN112367974A (zh) * 2018-05-15 2021-02-12 DNALite治疗学公司 粘液穿透肽、递送媒介和治疗方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153689A (en) * 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
JPS6068176A (ja) * 1983-09-26 1985-04-18 Kobe Steel Ltd 厚板Cr―Mo―V系耐熱鋼の突合わせ溶接方法
US4789660A (en) * 1987-09-10 1988-12-06 American Home Products Corporation Insulin administration using methyl and propyl paraben
JPH0242027A (ja) 1988-08-02 1990-02-13 Minofuaagen Seiyaku Honpo:Goushi 経粘膜吸収促進剤及びこれを用いた経鼻投与剤
CA2135642C (en) 1992-08-21 1999-12-14 James G. Barsoum Tat-derived transport polypeptides
ATE285212T1 (de) * 1993-10-07 2005-01-15 Odontex Inc Absorptionsförderer für topische pharmazeutische formulierungen
KR19990063632A (ko) * 1995-09-21 1999-07-26 디 헤이쓰, 산드라 우드 약물 운송용 트란스사이토시스 매개체 및 상승제
JP3770666B2 (ja) 1996-09-20 2006-04-26 株式会社ティ・ティ・エス技術研究所 経粘膜吸収製剤用組成物
GB9814527D0 (en) 1998-07-03 1998-09-02 Cyclacel Ltd Delivery system
ATE331532T1 (de) * 1998-08-26 2006-07-15 Teijin Ltd Pulverförmige pernasale mittel
ATE419273T1 (de) 1998-11-13 2009-01-15 Cyclacel Ltd Translokationsvektoren abgeleitet von der antennapedia homeodomain helix 3
US6960431B2 (en) * 2001-08-22 2005-11-01 Myriad Genetics, Inc. Therapeutic compositions and methods for treating viral infection
US20040254146A1 (en) * 2002-05-21 2004-12-16 Nastech Pharmaceutical Company Inc. Carboxylate salts of galantamine and their pharmaceutical use
KR20050049525A (ko) 2002-10-11 2005-05-25 가부시키가이샤산와카가쿠켄큐쇼 Glp-1 유도체 및 그의 경점막 흡수형 제제
US7166575B2 (en) * 2002-12-17 2007-01-23 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity
US20040147027A1 (en) * 2003-01-28 2004-07-29 Troy Carol M. Complex for facilitating delivery of dsRNA into a cell and uses thereof
US7329638B2 (en) * 2003-04-30 2008-02-12 The Regents Of The University Of Michigan Drug delivery compositions
CN101018560A (zh) * 2004-09-15 2007-08-15 大塚制药株式会社 经粘膜用组合物及提高经粘膜吸收的方法
US7442682B2 (en) 2004-10-19 2008-10-28 Nitto Denko Corporation Transepithelial delivery of peptides with incretin hormone activities
JP5103748B2 (ja) * 2005-02-16 2012-12-19 東レ株式会社 医薬組成物
KR100729830B1 (ko) * 2005-03-24 2007-06-19 바이오스펙트럼 주식회사 페너트라틴을 이용하여 단백질의 세포투과를 증진시키는대장균용발현벡터
WO2006112738A1 (en) * 2005-04-19 2006-10-26 Auckland Uniservices Limited Novel peptides and methods for the treatment of inflammatory disorders
NZ566281A (en) * 2005-07-27 2010-08-27 Mdrna Inc Tight junction modulating peptide comprising the amino acid seqeunce CNGRCGGKKKLKLLLKLL and combinations thereof with therapeutic agents
KR20080084937A (ko) * 2005-11-04 2008-09-22 포휴먼텍(주) 융합 폴리펩타이드를 세포로 전달하는 방법
CA2646833C (en) * 2005-12-30 2019-07-30 Evonik Roehm Gmbh Peptides useful as cell-penetrating peptides
CA2654207A1 (en) * 2006-06-08 2007-12-21 Cpex Pharmaceuticals, Inc. Insulin composition
JP5076374B2 (ja) * 2006-06-28 2012-11-21 東レ株式会社 医薬組成物
US20080076701A1 (en) * 2006-08-18 2008-03-27 Nastech Pharmaceutical Company Inc. Dicer substrate rna peptide conjugates and methods for rna therapeutics

Also Published As

Publication number Publication date
EP2253326A4 (en) 2013-01-09
BRPI0906045B1 (pt) 2022-01-25
WO2009107766A1 (ja) 2009-09-03
MX2010009148A (es) 2010-12-06
ES2671024T3 (es) 2018-06-04
EP2253326A1 (en) 2010-11-24
JPWO2009107766A1 (ja) 2011-07-07
CN101959532B (zh) 2013-02-27
JP5212492B2 (ja) 2013-06-19
JP4711013B2 (ja) 2011-06-29
US8895503B2 (en) 2014-11-25
RU2470666C2 (ru) 2012-12-27
KR101585046B1 (ko) 2016-01-13
EP2253326B1 (en) 2018-04-04
AU2009218060B2 (en) 2014-08-28
KR20100135730A (ko) 2010-12-27
CA2716565A1 (en) 2009-09-03
US20110020280A1 (en) 2011-01-27
CN101959532A (zh) 2011-01-26
AU2009218060A1 (en) 2009-09-03
RU2010139769A (ru) 2012-04-10
JP2011084581A (ja) 2011-04-28
CA2716565C (en) 2017-09-12
PL2253326T3 (pl) 2018-09-28

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/02/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 15A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2763 DE 19-12-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.