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BRPI0905707A2 - Método para aumentar a solubilidade aquosa de um composto ativo e composição compreendendo um composto ativo - Google Patents

Método para aumentar a solubilidade aquosa de um composto ativo e composição compreendendo um composto ativo

Info

Publication number
BRPI0905707A2
BRPI0905707A2 BRPI0905707-2A BRPI0905707A BRPI0905707A2 BR PI0905707 A2 BRPI0905707 A2 BR PI0905707A2 BR PI0905707 A BRPI0905707 A BR PI0905707A BR PI0905707 A2 BRPI0905707 A2 BR PI0905707A2
Authority
BR
Brazil
Prior art keywords
active compound
increasing
composition
aqueous solubility
solubility
Prior art date
Application number
BRPI0905707-2A
Other languages
English (en)
Inventor
David Bradley Wurm
David A Wilson
Bruce A Barner
Cynthia L Rand
Matthew D Miller
Michael J Johnson
Original Assignee
Dow Global Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies Inc filed Critical Dow Global Technologies Inc
Publication of BRPI0905707A2 publication Critical patent/BRPI0905707A2/pt
Publication of BRPI0905707B1 publication Critical patent/BRPI0905707B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0905707-2A 2008-01-18 2009-01-05 Método para aumentar a solubilidade aquosa de um composto ativo e composição compreendendo um composto ativo BRPI0905707B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2193508P 2008-01-18 2008-01-18
US61/021,935 2008-01-18
PCT/US2009/030071 WO2009091622A1 (en) 2008-01-18 2009-01-05 Method to enhance aqueous solubility of poorly soluble actives using methoxypolyethylene glycol

Publications (2)

Publication Number Publication Date
BRPI0905707A2 true BRPI0905707A2 (pt) 2015-07-14
BRPI0905707B1 BRPI0905707B1 (pt) 2024-02-27

Family

ID=40545939

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0905707-2A BRPI0905707B1 (pt) 2008-01-18 2009-01-05 Método para aumentar a solubilidade aquosa de um composto ativo e composição compreendendo um composto ativo

Country Status (6)

Country Link
US (1) US8497303B2 (pt)
EP (1) EP2252262B1 (pt)
JP (1) JP2011510005A (pt)
CN (1) CN101909601B (pt)
BR (1) BRPI0905707B1 (pt)
WO (1) WO2009091622A1 (pt)

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TW200932107A (en) * 2008-01-18 2009-08-01 Dow Global Technologies Inc Stable, low VOC, low viscous biocidal formulations and method of making such formulations
CN102805080B (zh) * 2012-08-24 2014-10-15 广西田园生化股份有限公司 一种可用于防治农业病虫害的可溶性粒剂
JP6539274B2 (ja) 2013-08-12 2019-07-03 ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド 押出成形された即放性乱用抑止性丸剤
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
EP3169315B1 (en) 2014-07-17 2020-06-24 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
US20160106737A1 (en) 2014-10-20 2016-04-21 Pharmaceutical Manufacturing Research Services, Inc. Extended Release Abuse Deterrent Liquid Fill Dosage Form
CN106983734B (zh) * 2017-06-01 2018-09-14 海南妙音春制药有限公司 一种布洛芬缓释胶囊及其制备方法
CN107184565B (zh) * 2017-06-01 2018-04-03 海南妙音春制药有限公司 一种布洛芬缓释胶囊的制备方法

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Also Published As

Publication number Publication date
US20100286277A1 (en) 2010-11-11
CN101909601B (zh) 2013-06-26
BRPI0905707B1 (pt) 2024-02-27
EP2252262B1 (en) 2020-03-18
EP2252262A1 (en) 2010-11-24
CN101909601A (zh) 2010-12-08
JP2011510005A (ja) 2011-03-31
WO2009091622A1 (en) 2009-07-23
US8497303B2 (en) 2013-07-30

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/01/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.