BRPI0820960A2 - composição - Google Patents
composiçãoInfo
- Publication number
- BRPI0820960A2 BRPI0820960A2 BRPI0820960A BRPI0820960A BRPI0820960A2 BR PI0820960 A2 BRPI0820960 A2 BR PI0820960A2 BR PI0820960 A BRPI0820960 A BR PI0820960A BR PI0820960 A BRPI0820960 A BR PI0820960A BR PI0820960 A2 BRPI0820960 A2 BR PI0820960A2
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99246007P | 2007-12-05 | 2007-12-05 | |
| PCT/IB2008/003945 WO2009101475A2 (en) | 2007-12-05 | 2008-12-05 | Compositions for and methods of enhancing the immune response to antigens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0820960A2 true BRPI0820960A2 (pt) | 2017-05-09 |
| BRPI0820960B1 BRPI0820960B1 (pt) | 2020-04-07 |
| BRPI0820960B8 BRPI0820960B8 (pt) | 2021-05-25 |
Family
ID=40788916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0820960A BRPI0820960B8 (pt) | 2007-12-05 | 2008-12-05 | composição, composição farmacêutica, e uso da composição |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8211861B2 (pt) |
| EP (1) | EP2231145B1 (pt) |
| JP (1) | JP5813953B2 (pt) |
| KR (1) | KR101566847B1 (pt) |
| CN (1) | CN101917985B (pt) |
| AU (1) | AU2008350531B2 (pt) |
| BR (1) | BRPI0820960B8 (pt) |
| CA (1) | CA2708246C (pt) |
| DK (1) | DK2231145T3 (pt) |
| ES (1) | ES2525127T3 (pt) |
| PT (1) | PT2231145E (pt) |
| RU (1) | RU2537188C2 (pt) |
| WO (1) | WO2009101475A2 (pt) |
| ZA (1) | ZA201003964B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8916164B2 (en) * | 2007-08-29 | 2014-12-23 | Abivax | Methods of enhancing adjuvaticity of vaccine compositions |
| EP2058011A1 (en) * | 2007-11-07 | 2009-05-13 | Wittycell | Nkt cell activating gycolipids covalently bound antigens and/or drug |
| CN104379592B (zh) | 2012-04-26 | 2017-12-29 | 独立行政法人理化学研究所 | 新的氨基甲酸酯糖脂及其用途 |
| HUE054034T2 (hu) | 2014-03-13 | 2021-08-30 | Univ Basel | Mielin asszociált glikoprotein elleni IgM antitestekhez kapcsódó szénhidrát ligandumok |
| EP3350193B1 (en) | 2015-09-16 | 2020-12-23 | Universität Basel | Carbohydrate ligands that bind to antibodies against glycoepitopes of glycosphingolipids |
| MX2019002947A (es) | 2016-09-14 | 2019-07-22 | Abivax | Combinaciones que incluyen abx196 para el tratamiento de cancer. |
| WO2019053142A1 (en) * | 2017-09-13 | 2019-03-21 | Abivax | ABX196 FOR USE IN THE TREATMENT OF BLADDER CANCER |
| CN110241060B (zh) * | 2019-08-02 | 2020-10-09 | 青岛农业大学 | 一种水貂肺炎克雷伯氏菌及其应用 |
| EP4301374A4 (en) | 2021-03-01 | 2025-09-10 | Deciduous Therapeutics Inc | COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242800A (en) * | 1990-01-30 | 1993-09-07 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Receptor for pathogenic fungi |
| US5936076A (en) | 1991-08-29 | 1999-08-10 | Kirin Beer Kabushiki Kaisha | αgalactosylceramide derivatives |
| TW261533B (pt) * | 1992-07-16 | 1995-11-01 | Kirin Brewery | |
| JP3717512B2 (ja) | 1992-10-22 | 2005-11-16 | 麒麟麦酒株式会社 | 新規スフィンゴ糖脂質およびその使用 |
| KR100281265B1 (ko) * | 1993-04-15 | 2001-02-01 | 마나배 게이사꾸 | 신규한 스핀고당지질 및 그의 사용 |
| CA2162478A1 (en) | 1993-05-14 | 1994-11-24 | Shawn A. Defrees | Sialyl lex analogues as inhibitors of cellular adhesion |
| US5785975A (en) * | 1995-06-26 | 1998-07-28 | Research Triangle Pharmaceuticals | Adjuvant compositions and vaccine formulations comprising same |
| EP0821068A3 (en) * | 1996-03-29 | 1999-06-02 | Rohm And Haas Company | Novel sphingolipids and a process thereto |
| US6417167B1 (en) | 1997-02-05 | 2002-07-09 | Kirin Beer Kabushiki Kaisha | Lyophilized compositions containing shingoglycolipid and process for preparing them |
| DE69824301T2 (de) | 1997-02-05 | 2005-06-02 | Kirin Beer K.K. | Glycosphingolipide enthaltende gefriergetrocknete zusammensetzung |
| ID23495A (id) | 1997-04-10 | 2000-04-27 | Kirin Brewery | Zat-zat pengaktif sel nkt yang mengandung alpha-glikosilseramida |
| EP1049477A1 (en) | 1997-12-30 | 2000-11-08 | A+ Science Invest AB | Galactosylceramide, glucosylceramide, lactosylceramide, and specific catchers therefor for use in the prophylaxis or therapy of prediabetes, diabetes and/or associated complications |
| WO1999041266A1 (en) | 1998-02-12 | 1999-08-19 | Emory University | Sphingolipid derivatives and their methods of use |
| AU2001252599A1 (en) * | 2000-04-28 | 2001-11-12 | Orient Cancer Therapy Co., Ltd. | Remedies for cancer |
| JP4410913B2 (ja) * | 2000-06-12 | 2010-02-10 | 壽製薬株式会社 | 新規糖脂質誘導体の製造方法 |
| US20020115624A1 (en) * | 2000-06-22 | 2002-08-22 | Behar Samuel M. | Alpha gylcosylceramides for treating bacterial and fungal infections |
| AU2001286636A1 (en) * | 2000-08-25 | 2002-03-13 | Lysometrix Corporation | Method for assaying the activity of lysosomal enzymes |
| CA2453880A1 (en) * | 2001-07-25 | 2003-02-06 | New York University | Use of glycosylceramides as adjuvants for vaccines against infections and cancer |
| KR100549866B1 (ko) | 2001-08-22 | 2006-02-08 | 고려대학교 산학협력단 | 암치료 및 예방 제제 |
| WO2003039568A1 (fr) | 2001-11-06 | 2003-05-15 | Orient Cancer Therary Co.,Ltd. | Compositions anticancereuses |
| US7273853B2 (en) * | 2002-05-13 | 2007-09-25 | Enanta Pharmaceuticals, Inc. | 6-11 bicyclic ketolide derivatives |
| JP2005533057A (ja) | 2002-06-13 | 2005-11-04 | ニューヨーク・ユニバーシティ | 合成ｃ−糖脂質、ならびに癌、感染性疾患および自己免疫疾患を処置するための合成ｃ−糖脂質の使用 |
| US7645873B2 (en) * | 2003-03-20 | 2010-01-12 | The Scripps Research Institute | 6″-amino-6″-deoxygalactosylceramides |
| GB0314682D0 (en) | 2003-06-24 | 2003-07-30 | Isis Innovation | Materials and methods relating to the modulation of T cell response to soluble antigen |
| US7771726B2 (en) | 2003-10-08 | 2010-08-10 | New York University | Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases |
| EP1732384A4 (en) | 2004-03-31 | 2008-04-23 | Univ New York State Res Found | NOVEL SYNTHETIC C-GLYCOLIPIDES, THEIR SYNTHESIS AND USE FOR THE TREATMENT OF INFECTIONS, CANCER AND AUTOIMMUNE DISEASES |
| WO2006029010A2 (en) | 2004-09-03 | 2006-03-16 | The University Of Chicago | Methods of activating nkt cells |
| CA2591232C (en) | 2004-12-28 | 2014-10-21 | The Rockefeller University | Glycolipids and analogues thereof as antigens for nk t cells |
| AU2006211485B2 (en) | 2005-01-28 | 2011-04-14 | Brigham Young University | Bacterial glycolipid activation of CD1d-restricted NKT cells |
| KR100764678B1 (ko) | 2005-07-13 | 2007-10-09 | 재단법인서울대학교산학협력재단 | 알파-갈락토실세라마이드를 아쥬반트로 포함하는 비강투여용 백신 조성물 |
| EP1776963A1 (en) * | 2005-10-19 | 2007-04-25 | Gbf-Gesellschaft Für Biotechnologische Forschung Mbh | Hexosylceramides as adjuvants and their uses in pharmaceutical compositions |
| EP1945651B1 (en) | 2005-10-25 | 2014-06-25 | The Ludwig Institute for Cancer Research | Analogs of alpha galactosylceramide and uses thereof |
| CA2661789C (en) | 2006-04-07 | 2014-06-03 | The Scripps Research Institute | Modified .alpha.-galactosyl ceramides for staining and stimulating natural killer t cells |
| CN101426523B (zh) | 2006-04-27 | 2013-03-27 | 财团法人首尔大学校产学协力财团 | 基于负载了天然杀伤t细胞的配体、和抗原的b细胞的疫苗 |
| CA2655947C (en) | 2006-06-30 | 2016-08-02 | The Scripps Research Institute | Compositions comprising nkt cell agonist compounds and methods of use |
| EP1938836A1 (en) * | 2006-12-28 | 2008-07-02 | Universite Rene Descartes (Paris V) | Compositions comprising a B subunit of shiga toxin and a means stimulating NKT cells |
| KR100868959B1 (ko) | 2006-12-30 | 2008-11-17 | 재단법인서울대학교산학협력재단 | 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물 |
| US8916164B2 (en) | 2007-08-29 | 2014-12-23 | Abivax | Methods of enhancing adjuvaticity of vaccine compositions |
| EP2058011A1 (en) | 2007-11-07 | 2009-05-13 | Wittycell | Nkt cell activating gycolipids covalently bound antigens and/or drug |
| EP2341931A1 (en) | 2008-10-08 | 2011-07-13 | Wittycell | Vaccine composition for use against influenza |
-
2008
- 2008-12-05 ES ES08872320.0T patent/ES2525127T3/es active Active
- 2008-12-05 WO PCT/IB2008/003945 patent/WO2009101475A2/en not_active Ceased
- 2008-12-05 CA CA2708246A patent/CA2708246C/en active Active
- 2008-12-05 US US12/746,488 patent/US8211861B2/en active Active
- 2008-12-05 RU RU2010127339/15A patent/RU2537188C2/ru active
- 2008-12-05 DK DK08872320.0T patent/DK2231145T3/en active
- 2008-12-05 US US12/315,702 patent/US8207135B2/en active Active
- 2008-12-05 PT PT88723200T patent/PT2231145E/pt unknown
- 2008-12-05 EP EP08872320.0A patent/EP2231145B1/en active Active
- 2008-12-05 JP JP2010536551A patent/JP5813953B2/ja active Active
- 2008-12-05 BR BRPI0820960A patent/BRPI0820960B8/pt active IP Right Grant
- 2008-12-05 CN CN200880119602.1A patent/CN101917985B/zh active Active
- 2008-12-05 AU AU2008350531A patent/AU2008350531B2/en active Active
- 2008-12-05 KR KR1020107014861A patent/KR101566847B1/ko active Active
-
2010
- 2010-06-03 ZA ZA2010/03964A patent/ZA201003964B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2231145B1 (en) | 2014-09-17 |
| US8211861B2 (en) | 2012-07-03 |
| CA2708246C (en) | 2016-05-24 |
| KR101566847B1 (ko) | 2015-11-06 |
| AU2008350531B2 (en) | 2014-01-23 |
| JP2011506306A (ja) | 2011-03-03 |
| RU2010127339A (ru) | 2012-01-10 |
| AU2008350531A1 (en) | 2009-08-20 |
| DK2231145T3 (en) | 2014-12-08 |
| BRPI0820960B1 (pt) | 2020-04-07 |
| US8207135B2 (en) | 2012-06-26 |
| PT2231145E (pt) | 2014-12-23 |
| JP5813953B2 (ja) | 2015-11-17 |
| US20090162385A1 (en) | 2009-06-25 |
| WO2009101475A2 (en) | 2009-08-20 |
| CN101917985B (zh) | 2014-07-02 |
| BRPI0820960B8 (pt) | 2021-05-25 |
| CN101917985A (zh) | 2010-12-15 |
| ES2525127T3 (es) | 2014-12-17 |
| KR20100094556A (ko) | 2010-08-26 |
| WO2009101475A3 (en) | 2009-10-22 |
| US20100322952A1 (en) | 2010-12-23 |
| CA2708246A1 (en) | 2009-08-20 |
| ZA201003964B (en) | 2011-02-23 |
| EP2231145A2 (en) | 2010-09-29 |
| RU2537188C2 (ru) | 2014-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: ABIVAX (FR) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 07/04/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/12/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |