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BRPI0820520B8 - processo para a fabricação de formas de dosagem mastigáveis para a liberação de fármacos e produtos dos mesmos - Google Patents

processo para a fabricação de formas de dosagem mastigáveis para a liberação de fármacos e produtos dos mesmos

Info

Publication number
BRPI0820520B8
BRPI0820520B8 BRPI0820520A BRPI0820520A BRPI0820520B8 BR PI0820520 B8 BRPI0820520 B8 BR PI0820520B8 BR PI0820520 A BRPI0820520 A BR PI0820520A BR PI0820520 A BRPI0820520 A BR PI0820520A BR PI0820520 B8 BRPI0820520 B8 BR PI0820520B8
Authority
BR
Brazil
Prior art keywords
drugs
release
manufacture
products
dosage forms
Prior art date
Application number
BRPI0820520A
Other languages
English (en)
Inventor
Coffee Michael
E Paulsen Neil
Johnson Roland
Original Assignee
Piedmont Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40639740&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0820520(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Piedmont Pharmaceuticals Llc filed Critical Piedmont Pharmaceuticals Llc
Publication of BRPI0820520A2 publication Critical patent/BRPI0820520A2/pt
Publication of BRPI0820520B1 publication Critical patent/BRPI0820520B1/pt
Publication of BRPI0820520B8 publication Critical patent/BRPI0820520B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

processo para a fabricação de formas de dosagem mastigáveis para a liberação de fármacos e produtos dos mesmos. a presente invenção refere-se a um veículo de medicação mastigável macio comestível palatável para a liberação de um ingrediente ativo farmaceuticaamente aceitável tal como um fármaco a um animal ou ser humano. os mastigáveis macios comestíveis contêm apenas ingredientes de grau alimentício, ou melhor, inativos, e preferivelmente não contêm ingredientes de origem animal. os processos para a fabricação dos mastigáveis macios comestíveis não requerem o uso de calor ou adição de água durante a mistura de ingredientes ativos e inativos, fornecem concentrações estáveis do ingrediente ativo, e produzem mastigáveis de peso e textura consistentes.
BRPI0820520A 2007-11-14 2008-11-13 processo para a fabricação de formas de dosagem mastigáveis para a liberação de fármacos e produtos dos mesmos BRPI0820520B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/940,106 US7955632B2 (en) 2005-12-07 2007-11-14 Process for manufacturing chewable dosage forms for drug delivery and products thereof
US11/940,106 2007-11-14
PCT/US2008/083373 WO2009064859A1 (en) 2007-11-14 2008-11-13 Process for manufacturing chewable dosage forms for drug delivery and products thereof

Publications (3)

Publication Number Publication Date
BRPI0820520A2 BRPI0820520A2 (pt) 2017-05-23
BRPI0820520B1 BRPI0820520B1 (pt) 2020-10-06
BRPI0820520B8 true BRPI0820520B8 (pt) 2021-05-25

Family

ID=40639740

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0820520A BRPI0820520B8 (pt) 2007-11-14 2008-11-13 processo para a fabricação de formas de dosagem mastigáveis para a liberação de fármacos e produtos dos mesmos

Country Status (10)

Country Link
US (5) US7955632B2 (pt)
EP (2) EP2656838A1 (pt)
JP (1) JP2011503197A (pt)
CN (1) CN101909605B (pt)
AU (3) AU2008320992B2 (pt)
BR (1) BRPI0820520B8 (pt)
CA (1) CA2705724C (pt)
RU (1) RU2519670C2 (pt)
WO (1) WO2009064859A1 (pt)
ZA (2) ZA201003245B (pt)

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US8114455B2 (en) 2012-02-14
AU2015203843B2 (en) 2018-05-31
US7955632B2 (en) 2011-06-07
US8865240B2 (en) 2014-10-21
AU2008320992B2 (en) 2015-04-09
EP2656838A1 (en) 2013-10-30
AU2015203843A1 (en) 2015-07-30
EP2219626A1 (en) 2010-08-25
BRPI0820520B1 (pt) 2020-10-06
BRPI0820520A2 (pt) 2017-05-23
AU2008320992A1 (en) 2009-05-22
AU2018223006A1 (en) 2018-09-20
US20150224052A1 (en) 2015-08-13
CN101909605A (zh) 2010-12-08
US20120141574A1 (en) 2012-06-07
RU2519670C2 (ru) 2014-06-20
US20130331348A1 (en) 2013-12-12
US20080075759A1 (en) 2008-03-27
WO2009064859A1 (en) 2009-05-22
CN101909605B (zh) 2013-07-24
EP2219626A4 (en) 2012-11-21
CA2705724A1 (en) 2009-05-22
US9381155B2 (en) 2016-07-05
US8512787B2 (en) 2013-08-20
CA2705724C (en) 2016-04-05
JP2011503197A (ja) 2011-01-27
US20110223234A1 (en) 2011-09-15
ZA201105604B (en) 2013-03-27
RU2010123868A (ru) 2011-12-20

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