BRPI0813966A2 - Usos de mdl-1 - Google Patents

Usos de mdl-1

Info

Publication number: BRPI0813966A2
Authority: BR; Brazil
Prior art keywords: cdm
Prior art date: 2007-06-29

Application number

BRPI0813966-0A2A

Other languages

English (en)

Inventor

Michael E Bigler

Daniel J Cua

Barbara Joyce-Shaikh

Joseph H Phillips

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-29

Filing date

2008-06-24

Publication date

2015-01-06

2008-06-24 Application filed by Schering Corp filed Critical Schering Corp

2015-01-06 Publication of BRPI0813966A2 publication Critical patent/BRPI0813966A2/pt

2016-02-10 Publication of BRPI0813966A8 publication Critical patent/BRPI0813966A8/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Mycology (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BRPI0813966A 2007-06-29 2008-06-24 Usos de mdl-1 BRPI0813966A8 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US94731407P	2007-06-29	2007-06-29
PCT/US2008/068042 WO2009006112A1 (en)	2007-06-29	2008-06-24	Mdl-1 uses

Publications (2)

Publication Number	Publication Date
BRPI0813966A2 true BRPI0813966A2 (pt)	2015-01-06
BRPI0813966A8 BRPI0813966A8 (pt)	2016-02-10

Family

ID=39712082

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0813966A BRPI0813966A8 (pt)	2007-06-29	2008-06-24	Usos de mdl-1

Country Status (10)

Country	Link
US (2)	US20100221252A1 (pt)
EP (1)	EP2176294B1 (pt)
JP (2)	JP5171948B2 (pt)
CN (1)	CN101802011A (pt)
AU (1)	AU2008270710A1 (pt)
BR (1)	BRPI0813966A8 (pt)
CA (1)	CA2691618A1 (pt)
ES (1)	ES2540854T3 (pt)
WO (1)	WO2009006112A1 (pt)
ZA (1)	ZA201000393B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK2009101T3 (en)	2006-03-31	2018-01-15	Chugai Pharmaceutical Co Ltd	Antibody modification method for purification of a bispecific antibody
JP5166398B2 (ja)	2006-04-07	2013-03-21	エアーピオセラピューティクスインコーポレイテッド	ヒトタンパク質チロシンホスファターゼβ（ＨＰＴＰβ）に結合する抗体及びその使用
WO2011053630A1 (en) *	2009-10-30	2011-05-05	Schering Corporation	Uses of a mammalian cytokine
PT2647707T (pt)	2010-11-30	2018-11-15	Chugai Pharmaceutical Co Ltd	Agente terapêutico indutor de toxicidade
EP2675467A4 (en) *	2011-02-18	2014-06-25	Merck Sharp & Dohme	USE OF MDL-1 ANTAGONISTS FOR THE TREATMENT OF SPONDYLARTHROPATHY
WO2013043516A1 (en)	2011-09-23	2013-03-28	Merck Sharp & Dohme Corp.	Mdl-1 ligand
EP2766044B1 (en)	2011-10-13	2019-12-11	Aerpio Therapeutics, Inc.	Treatment of ocular disease
EP3505182A1 (en)	2011-10-13	2019-07-03	Aerpio Therapeutics, Inc.	Methods for treating vascular leak syndrome and cancer
KR102398736B1 (ko)	2011-10-31	2022-05-16	추가이 세이야쿠 가부시키가이샤	중쇄와 경쇄의 회합이 제어된 항원 결합 분자
DK2780373T3 (da)	2011-11-16	2019-11-04	Boehringer Ingelheim Int	Anti-IL-36R-antistoffer
AU2015244814B2 (en)	2014-04-07	2020-12-24	Chugai Seiyaku Kabushiki Kaisha	Immunoactivating antigen-binding molecule
EA201692287A1 (ru)	2014-05-13	2017-06-30	Чугаи Сеияку Кабушики Каиша	Антигенсвязывающая молекула, перенаправляющая т-клетки на клетки, обладающие иммуносупрессорной функцией
MA40764A (fr)	2014-09-26	2017-08-01	Chugai Pharmaceutical Co Ltd	Agent thérapeutique induisant une cytotoxicité
WO2017086367A1 (ja)	2015-11-18	2017-05-26	中外製薬株式会社	免疫抑制機能を有する細胞に対するｔ細胞リダイレクト抗原結合分子を用いた併用療法
JP6925278B2 (ja)	2015-11-18	2021-08-25	中外製薬株式会社	液性免疫応答の増強方法
CN108368166B (zh)	2015-12-28	2023-03-28	中外制药株式会社	提高含fc区多肽纯化效率的方法
TW202342540A (zh)	2016-03-14	2023-11-01	日商中外製藥股份有限公司	用於癌之治療的細胞傷害誘導治療劑
MX2020009544A (es)	2018-03-14	2020-10-05	Boehringer Ingelheim Int	Uso de anticuerpos anti-il-36r para el tratamiento de la psoriasis pustulosa generalizada.
US10894824B2 (en)	2018-09-24	2021-01-19	Aerpio Pharmaceuticals, Inc.	Multispecific antibodies that target HPTP-β (VE-PTP) and VEGF
BR112021016198A2 (pt)	2019-03-08	2021-11-03	Boehringer Ingelheim Int	Formulações de anticorpo anti-il-36r
WO2021006328A1 (en)	2019-07-10	2021-01-14	Chugai Seiyaku Kabushiki Kaisha	Claudin-6 binding molecules and uses thereof
JP2023534955A (ja)	2020-07-17	2023-08-15	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	好中球性皮膚症の処置のための抗ｉｌ－３６ｒ抗体
CN115779071B (zh) *	2022-11-04	2024-12-24	济宁医学院附属医院	Mdl-1在制备缺血性脑卒中后脑保护药物中的应用
TW202517686A (zh) *	2023-07-13	2025-05-01	大陸商深圳澤安生物醫藥有限公司	多特異性抗體及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6416973B1 (en) *	1997-08-01	2002-07-09	Schering Corporation	Nucleic acids encoding mammalian cell membrane protein MDL-1
WO2005027848A2 (en) *	2003-09-19	2005-03-31	Barnes-Jewish Hospital	Methods for screening osteogenic compounds targeting syk kinase and/or vav3 and uses of syk modulators and/or vav modulators
AR059193A1 (es)	2006-01-31	2008-03-12	Bayer Schering Pharma Ag	Modulacion de la actividad de mdl-1 para el tratamiento de enfermedades inflamatorias
JP2010526066A (ja) *	2007-04-23	2010-07-29	シェーリングコーポレイション	抗ｍｄｌ−１抗体

2008
- 2008-06-24 AU AU2008270710A patent/AU2008270710A1/en not_active Abandoned
- 2008-06-24 JP JP2010515038A patent/JP5171948B2/ja not_active Expired - Fee Related
- 2008-06-24 US US12/665,009 patent/US20100221252A1/en not_active Abandoned
- 2008-06-24 BR BRPI0813966A patent/BRPI0813966A8/pt not_active IP Right Cessation
- 2008-06-24 ES ES08771835.9T patent/ES2540854T3/es active Active
- 2008-06-24 EP EP20080771835 patent/EP2176294B1/en active Active
- 2008-06-24 WO PCT/US2008/068042 patent/WO2009006112A1/en not_active Ceased
- 2008-06-24 CA CA002691618A patent/CA2691618A1/en not_active Abandoned
- 2008-06-24 CN CN200880106199A patent/CN101802011A/zh active Pending
2010
- 2010-01-19 ZA ZA2010/00393A patent/ZA201000393B/en unknown
2012
- 2012-03-23 US US13/428,929 patent/US20120177647A1/en not_active Abandoned
- 2012-08-28 JP JP2012187524A patent/JP2012233008A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
CA2691618A1 (en)	2009-01-08
JP2010532369A (ja)	2010-10-07
JP5171948B2 (ja)	2013-03-27
ZA201000393B (en)	2014-03-26
WO2009006112A1 (en)	2009-01-08
EP2176294A1 (en)	2010-04-21
AU2008270710A1 (en)	2009-01-08
ES2540854T3 (es)	2015-07-14
JP2012233008A (ja)	2012-11-29
EP2176294B1 (en)	2015-05-20
CN101802011A (zh)	2010-08-11
US20100221252A1 (en)	2010-09-02
US20120177647A1 (en)	2012-07-12
BRPI0813966A8 (pt)	2016-02-10

Publication	Publication Date	Title
BRPI0813966A2 (pt)	2015-01-06	Usos de mdl-1
BRPI0818380A2 (pt)	2014-10-07	Combinação de herbicida-protetor
BRPI0813707A2 (pt)	2014-12-30	Derivados de pirimidinil-piridazinona
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
EP2170350A4 (en)	2011-09-28	SUBSTITUTED IMIDAZOHETEROCYCLES
ATE542825T1 (de)	2012-02-15	Substituierte piperidino-dihydrothienopyrimidine
DK2203462T4 (da)	2024-12-16	Nukleosid-phosphoramidat-prodrugs
BRPI0810191A2 (pt)	2014-12-30	Escova de dentes
DE602008006301D1 (de)	2011-06-01	Koaxialnadelanordnung
BRPI0812155A2 (pt)	2019-09-24	derivados de espiroindolinona
BRPI0821573A2 (pt)	2016-08-09	benzofuropirimidonas
BRPI0817935A2 (pt)	2015-04-07	Derivados de biarila
DK2514750T3 (da)	2013-12-02	Bromphenylsubstituerede thiazolyldihydropyrimidiner
BRPI0814236A2 (pt)	2015-01-06	Derivados de quinazolinamida
EP2152479A4 (en)	2015-03-25	TREE SHEAR
DE112008003636A5 (de)	2010-10-21	Mehrzuggruppierer
BRPI0812518A2 (pt)	2015-03-31	Derivados de indazolamida
EP2165942A4 (en)	2012-01-11	Plug structure
EP2160187A4 (en)	2011-08-03	SPIROINDALONE
BRPI0820649A2 (pt)	2015-06-16	Derivados de isoxazalo-pirazina
EP2149500A4 (en)	2010-09-08	Electron beam sterilizer
EP2211752A4 (en)	2013-10-02	biopulp
BRPI0812994A2 (pt)	2014-12-23	Microbiocidas

Legal Events

Date	Code	Title	Description
2015-10-13	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2016-02-10	B25D	Requested change of name of applicant approved	Owner name: MERCK SHARP AND DOHME CORP. (US)
2016-02-23	B25G	Requested change of headquarter approved	Owner name: MERCK SHARP AND DOHME CORP. (US)
2016-03-29	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.