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BRPI0813710A2 - Enzimas que produzem acetil-coa em levedura - Google Patents

Enzimas que produzem acetil-coa em levedura

Info

Publication number
BRPI0813710A2
BRPI0813710A2 BRPI0813710-2A2A BRPI0813710A BRPI0813710A2 BR PI0813710 A2 BRPI0813710 A2 BR PI0813710A2 BR PI0813710 A BRPI0813710 A BR PI0813710A BR PI0813710 A2 BRPI0813710 A2 BR PI0813710A2
Authority
BR
Brazil
Prior art keywords
coa
yeast
enzymes
produce acetyl
acetyl
Prior art date
Application number
BRPI0813710-2A2A
Other languages
English (en)
Inventor
Ulrike Maria Mueller
Liang Wu
Lourina Madeleine Raamsdonk
Aaron Adriaan Winkler
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of BRPI0813710A2 publication Critical patent/BRPI0813710A2/pt
Publication of BRPI0813710B1 publication Critical patent/BRPI0813710B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0813710A 2007-07-23 2008-07-11 método de identificar um polipeptídeo heterólogo tendo atividade enzimática para converter piruvato, acetaldeído ou acetato em acetil-coa no citosol de uma célula de levedura, vetor para a expressão de polipeptídeos heterólogos em levedura, célula de levedura recombinante e método de produzir um produto de fermentação BRPI0813710B1 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US93503107P 2007-07-23 2007-07-23
EP07112956 2007-07-23
EP07123976 2007-12-21
US6412008P 2008-02-19 2008-02-19
EP08101747 2008-02-19
PCT/EP2008/059119 WO2009013159A2 (en) 2007-07-23 2008-07-11 Acetyl-coa producing enzymes in yeast

Publications (2)

Publication Number Publication Date
BRPI0813710A2 true BRPI0813710A2 (pt) 2014-10-07
BRPI0813710B1 BRPI0813710B1 (pt) 2018-10-09

Family

ID=40281027

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813710A BRPI0813710B1 (pt) 2007-07-23 2008-07-11 método de identificar um polipeptídeo heterólogo tendo atividade enzimática para converter piruvato, acetaldeído ou acetato em acetil-coa no citosol de uma célula de levedura, vetor para a expressão de polipeptídeos heterólogos em levedura, célula de levedura recombinante e método de produzir um produto de fermentação

Country Status (6)

Country Link
US (4) US20100248233A1 (pt)
EP (1) EP2173881B1 (pt)
CN (2) CN101939433B (pt)
BR (1) BRPI0813710B1 (pt)
PL (1) PL2173881T3 (pt)
WO (2) WO2009013157A1 (pt)

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SG181607A1 (en) 2009-12-10 2012-07-30 Genomatica Inc Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
US9605269B2 (en) * 2010-05-05 2017-03-28 Lallemand Hungary Liquidity Management Llc Detoxification of biomass derived acetate via metabolic conversion to ethanol, acetone, isopropanol, or ethyl acetate
WO2011149353A1 (en) * 2010-05-27 2011-12-01 C5 Yeast Company B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
EP2580341A4 (en) * 2010-06-11 2014-04-23 Univ California SYNTHETIC STRIPS FOR BIOFUEL SYNTHESIS
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
ES2645680T3 (es) * 2010-11-22 2017-12-07 Cargill, Incorporated Células de levadura y proceso para convertir acetaldehído en etanol
AU2012273177A1 (en) * 2011-06-22 2013-05-02 Genomatica, Inc. Microorganisms for producing 1,3-butanediol and methods related thereto
WO2013071172A1 (en) 2011-11-09 2013-05-16 Amyris, Inc. Production of acetyl-coenzyme a derived isoprenoids
US20140322779A1 (en) * 2011-11-11 2014-10-30 Genomatica, Inc. Eukaryotic organisms and methods for increasing the availability of cytosolic acetyl-coa, and for the producing 1,3-butanediol
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IN2015DN01041A (pt) * 2012-08-28 2015-06-26 Dsm Ip Assets Bv
WO2014033019A1 (en) * 2012-08-28 2014-03-06 Dsm Ip Assets B.V. Yeast strains engineered to produce ethanol from acetate
CA2884266C (en) 2012-09-14 2022-05-24 Myriant Corporation Production of organic acids by fermentation at low ph
PL2958986T3 (pl) 2013-02-22 2023-01-02 Dsm Ip Assets B.V. Rekombinowany mikroorganizm do zastosowania w sposobie o zwiększonej wydajności produktu
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EP2971027B1 (en) 2013-03-15 2019-01-30 Amyris, Inc. Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds
EP3008178A1 (en) * 2013-06-14 2016-04-20 Technical University of Denmark Microbial production of 3-hydroxypropionic acid
WO2014207113A1 (en) 2013-06-26 2014-12-31 Abengoa Bioenergia Nuevas Tecnologias S.A. Yeasts engineered for the production of valuable chemicals from sugars
US9663759B2 (en) 2013-07-03 2017-05-30 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
AR097480A1 (es) 2013-08-29 2016-03-16 Dsm Ip Assets Bv Células de levadura convertidoras de glicerol y ácido acético con una conversión de ácido acético mejorada
WO2015057154A2 (en) 2013-10-18 2015-04-23 Biopetrolia Ab ENGINEERING OF ACETYL-CoA METABOLISM IN YEAST
KR101577134B1 (ko) 2014-05-09 2015-12-14 씨제이제일제당 (주) 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
JP6034332B2 (ja) * 2014-05-30 2016-11-30 トヨタ自動車株式会社 組換え微生物及び当該組換え微生物を用いた物質製造方法
BR112017004069B1 (pt) * 2014-08-29 2024-02-06 Sk Innovation Co., Ltd Levedura recombinante produzindo ácido 3-hidroxipropiônico e método para produzir ácido 3-hidroxipropiônico usando o mesmo
WO2016191734A1 (en) * 2015-05-28 2016-12-01 University Of California Berkeley Monofunctional aldehyde and alcohol dehydrogenases for production of fuels and commodity chemicals
US10155967B2 (en) 2015-06-12 2018-12-18 Cj Cheiljedang Corporation Microorganism having enhanced productivity of lactic acid and a process for producing lactic acid using the same
ES2767728T3 (es) 2015-10-06 2020-06-18 Dsm Ip Assets Bv Célula eucariota con elevada producción de producto de fermentación
WO2017216136A1 (en) 2016-06-14 2017-12-21 Dsm Ip Assets B.V. Recombinant yeast cell
ES2924108T3 (es) 2016-12-20 2022-10-04 Dsm Ip Assets Bv Cepas de levadura mejoradas para la producción de etanol
CN110088275A (zh) 2016-12-23 2019-08-02 帝斯曼知识产权资产管理有限公司 改进的无甘油的乙醇生产
US20200024619A1 (en) * 2017-03-21 2020-01-23 Dsm Ip Assets B.V. Improved glycerol free ethanol production
CN111032854A (zh) 2017-06-13 2020-04-17 帝斯曼知识产权资产管理有限公司 重组酵母细胞
EP3730145A1 (en) * 2017-07-11 2020-10-28 Trait Biosciences, Inc. Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter
UY37835A (es) * 2017-08-08 2019-03-29 Danisco Us Inc Producción incrementada de etanol por levaduras que albergan alelos del activador de transcripción constitutivo mal
CN111133111A (zh) 2017-09-26 2020-05-08 帝斯曼知识产权资产管理有限公司 消耗乙酸的菌株
US20200283805A1 (en) 2017-09-26 2020-09-10 Dsm Ip Assets B.V. Improved process for ethanol production
US11384368B2 (en) 2017-09-29 2022-07-12 Dsm Ip Assets B.V. Glycerol free ethanol production
WO2019067412A1 (en) * 2017-09-29 2019-04-04 Dow Global Technologies Llc GENETICALLY MODIFIED ISOPROPYLMALATE ISOMERASE ENZYME COMPLEXES AND METHODS FOR PREPARING ELONGATE 2-CÉTOACIDES AND C5-C10 COMPOUNDS THEREWITH
CN111148840B (zh) 2017-09-29 2024-08-30 丹尼斯科美国公司 改进的无甘油乙醇生产
US10310281B1 (en) * 2017-12-05 2019-06-04 K Laser Technology, Inc. Optical projector with off-axis diffractive element
WO2019110491A1 (en) 2017-12-08 2019-06-13 Dsm Ip Assets B.V. Recombinant yeast cell
WO2019110492A1 (en) 2017-12-08 2019-06-13 Dsm Ip Assets B.V. Recombinant yeast cell
WO2020043497A1 (en) 2018-08-28 2020-03-05 Dsm Ip Assets B.V. Process for the production of ethanol
BR112022007870A2 (pt) 2019-11-08 2022-07-12 Dsm Ip Assets Bv Processo para produzir etanol
CN110951660B (zh) * 2019-12-19 2021-12-03 江南大学 一株固定co2产苹果酸的大肠杆菌工程菌的构建及应用
CN113528366B (zh) * 2021-07-15 2023-12-08 洛阳华荣生物技术有限公司 一种产beta-丙氨酸酵母菌及其构建方法
CN114181964B (zh) * 2021-11-02 2023-06-09 云南大学 一种表达盒组合、重组载体和重组酿酒酵母及其应用
CN115011616B (zh) * 2022-01-26 2023-07-21 昆明理工大学 一种乙醛脱氢酶基因rkaldh及其应用
CN116376995B (zh) * 2022-04-02 2024-01-26 元素驱动(杭州)生物科技有限公司 一种利用苏氨酸制备甘氨酸、乙酰辅酶a及乙酰辅酶a衍生物的方法
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Also Published As

Publication number Publication date
EP2173881A2 (en) 2010-04-14
WO2009013157A1 (en) 2009-01-29
BRPI0813710B1 (pt) 2018-10-09
WO2009013159A2 (en) 2009-01-29
US20240191277A1 (en) 2024-06-13
CN101939433B (zh) 2015-05-20
EP2173881B1 (en) 2016-09-28
CN104789638A (zh) 2015-07-22
US20210054433A1 (en) 2021-02-25
US20100248233A1 (en) 2010-09-30
WO2009013159A3 (en) 2009-04-23
CN101939433A (zh) 2011-01-05
PL2173881T3 (pl) 2017-05-31
US20140030730A1 (en) 2014-01-30
US10927399B2 (en) 2021-02-23

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/10/2018, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: DANISCO US INC. (US)