BRPI0813127A8 - Rosa contendo flavona e malvidina e método para produção da mesma - Google Patents
Rosa contendo flavona e malvidina e método para produção da mesmaInfo
- Publication number
- BRPI0813127A8 BRPI0813127A8 BRPI0813127A BRPI0813127A BRPI0813127A8 BR PI0813127 A8 BRPI0813127 A8 BR PI0813127A8 BR PI0813127 A BRPI0813127 A BR PI0813127A BR PI0813127 A BRPI0813127 A BR PI0813127A BR PI0813127 A8 BRPI0813127 A8 BR PI0813127A8
- Authority
- BR
- Brazil
- Prior art keywords
- gene
- flavone
- malvidine
- scrophulariaceae
- family
- Prior art date
Links
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 title abstract 4
- 229930003944 flavone Natural products 0.000 title abstract 4
- 150000002212 flavone derivatives Chemical class 0.000 title abstract 4
- 235000011949 flavones Nutrition 0.000 title abstract 4
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 title abstract 4
- 241000220317 Rosa Species 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 101710130467 Flavone synthase Proteins 0.000 abstract 5
- 241000013557 Plantaginaceae Species 0.000 abstract 4
- KZMACGJDUUWFCH-UHFFFAOYSA-O malvidin Chemical compound COC1=C(O)C(OC)=CC(C=2C(=CC=3C(O)=CC(O)=CC=3[O+]=2)O)=C1 KZMACGJDUUWFCH-UHFFFAOYSA-O 0.000 abstract 4
- 108010062650 Flavonoid 3',5'-hydroxylase Proteins 0.000 abstract 3
- 108060004795 Methyltransferase Proteins 0.000 abstract 3
- 241000960400 Torenia Species 0.000 abstract 2
- 244000225942 Viola tricolor Species 0.000 abstract 2
- 235000004031 Viola x wittrockiana Nutrition 0.000 abstract 2
- 229930002877 anthocyanin Natural products 0.000 abstract 2
- 235000010208 anthocyanin Nutrition 0.000 abstract 2
- 239000004410 anthocyanin Substances 0.000 abstract 2
- 150000004636 anthocyanins Chemical class 0.000 abstract 2
- 235000009584 malvidin Nutrition 0.000 abstract 2
- 241000207875 Antirrhinum Species 0.000 abstract 1
- 238000012239 gene modification Methods 0.000 abstract 1
- 230000005017 genetic modification Effects 0.000 abstract 1
- 235000013617 genetically modified food Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/825—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
- C12Y114/11022—Flavone synthase (1.14.11.22)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
- C12Y114/13088—Flavonoid 3',5'-hydroxylase (1.14.13.88)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/01—Methyltransferases (2.1.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
ROSA CONTENDO FLAVONA E MALVIDINA E MÉTODO PARA PRODUÇÃO DA MESMA. A presente invenção refere-se a uma rosa caracterizada por compreender uma flavona e malvidina adicionadas por um método de modificação genética. A flavona e malvidina são tipicamente produzidas por expressão de um gene de flavona sintase transferido, gene de flavonóide 3',5'-hidroxilase de amor-perfeito e gene de antocianina metiltransferase. O gene de flavona sintase é, por exemplo, um gene de flavona sintase da família Scrophulariaceae, e especificamente pode ser o gene de flavona sintase de boca-de-leão da família Scrophulariaceae, ou o gene de flavona sintase de torenia da família Scrophulariaceae. O gene de flavonóide 3',5'-hidroxilase é, por exemplo, o gene de flavonóide 3',5'-hidroxilase de amor-perfeito. O gene de antocianina metiltransferase é, por exemplo, o gene de metiltransferase de torenia da família Scrophulariaceae.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007162959 | 2007-06-20 | ||
| PCT/JP2008/061593 WO2008156206A1 (ja) | 2007-06-20 | 2008-06-19 | フラボン及びマルビジンを含むバラ及びその生産方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0813127A2 BRPI0813127A2 (pt) | 2014-10-14 |
| BRPI0813127A8 true BRPI0813127A8 (pt) | 2016-06-07 |
Family
ID=40156355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0813127A BRPI0813127A8 (pt) | 2007-06-20 | 2008-06-19 | Rosa contendo flavona e malvidina e método para produção da mesma |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20100281575A1 (pt) |
| EP (1) | EP2163619B1 (pt) |
| JP (1) | JP5057349B2 (pt) |
| KR (1) | KR101168421B1 (pt) |
| CN (1) | CN101679972B (pt) |
| AU (1) | AU2008264434B2 (pt) |
| BR (1) | BRPI0813127A8 (pt) |
| CA (1) | CA2690754C (pt) |
| CO (1) | CO6170374A2 (pt) |
| EC (1) | ECSP099814A (pt) |
| ES (1) | ES2385416T3 (pt) |
| IL (1) | IL202818A (pt) |
| RU (1) | RU2463348C2 (pt) |
| TW (1) | TWI440430B (pt) |
| WO (1) | WO2008156206A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100287667A1 (en) * | 2007-06-20 | 2010-11-11 | International Flower Developments Proprietary Ltd | Rose containing flavone, and method for production thereof |
| JPWO2008156214A1 (ja) * | 2007-06-20 | 2010-08-26 | インターナショナル フラワー ディベロプメンツ プロプライアタリー リミティド | フラボン及びデルフィニジンを含むバラ及びその生産方法 |
| KR101659525B1 (ko) * | 2009-03-27 | 2016-09-23 | 산토리 홀딩스 가부시키가이샤 | 파란 장미에 함유되는 신규 화합물 |
| JP5697041B2 (ja) | 2009-04-24 | 2015-04-08 | 独立行政法人農業・食品産業技術総合研究機構 | 修飾されたアントシアニンを花弁に含有するキク植物を生産する方法 |
| CN105349553B (zh) * | 2015-12-17 | 2018-09-07 | 海南大学 | 一种花色调节基因VwMYB29及其应用 |
| CA3018690A1 (en) * | 2016-03-31 | 2017-10-05 | Suntory Holdings Limited | Plant having blue flower color and breeding method therefor |
| CN106754989B (zh) * | 2016-12-21 | 2020-04-21 | 广东药科大学 | 布渣叶黄烷酮-2-羟基化酶及其编码基因与应用 |
| CA3078387A1 (en) * | 2017-10-03 | 2019-04-11 | Suntory Holdings Limited | Transformed plant having blue flower color, and method for creating same |
| KR102010833B1 (ko) * | 2017-11-08 | 2019-08-16 | 대한민국 | 화훼식물의 꽃잎, 암술기관 및 화심 색 변형 기능 매발톱꽃 유래 신규 유전자 및 이의 용도 |
| CA3135580A1 (en) * | 2019-03-29 | 2020-10-08 | Suntory Holdings Limited | Flavone 7-o-methyltransferase gene and use for same |
| EP4039804A4 (en) * | 2019-10-01 | 2024-01-24 | Suntory Holdings Limited | Buckwheat-derived c-glycosyltransferase gene and utilization thereof |
| US20240010998A1 (en) * | 2020-11-18 | 2024-01-11 | Suntory Holdings Limited | Flavone 4'-o-methyltransferase gene and use for same |
| CN115094066B (zh) * | 2022-05-06 | 2023-11-14 | 上海师范大学 | 一种调控月季花瓣颜色的基因RcTTG1及其应用 |
| CN118557490A (zh) * | 2024-08-01 | 2024-08-30 | 湖州嘉亨实业有限公司 | 一种玫瑰提取复合物的制备方法及组合物 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5480789A (en) * | 1991-04-01 | 1996-01-02 | Florigene Europe B.V. | Genetically transformed rose plants and methods for their production |
| US5948955A (en) * | 1991-07-13 | 1999-09-07 | International Flower Developments Pty Ltd | Transgenic plants having altered anthocyann levels |
| WO1993018155A1 (fr) * | 1992-03-02 | 1993-09-16 | Kyowa Hakko Kogyo Co., Ltd. | Nouveau gene vegetal |
| US20010007157A1 (en) * | 1993-11-18 | 2001-07-05 | Ebrahim Firoozabady | Genetically transformed rose plants and methods for their production |
| US5568832A (en) * | 1994-10-18 | 1996-10-29 | Eddy; Zonell | Skylight shade |
| JPH0970290A (ja) * | 1995-02-17 | 1997-03-18 | Suntory Ltd | アシル基転移活性を有する蛋白質をコードする遺伝子 |
| AUPN298895A0 (en) * | 1995-05-16 | 1995-06-08 | International Flower Developments Pty Ltd | Transgenic plants exhibiting altered flower colour and methods for producing same |
| RO122151B1 (ro) * | 1998-01-22 | 2009-01-30 | National Research Council Of Canada | Procedeu de modificare a nivelurilor concentraţiilor de compuşi metabolici secundari, din plante |
| JP4368005B2 (ja) * | 1999-01-29 | 2009-11-18 | インターナショナル フラワー ディベロプメンツ プロプライアタリー リミティド | フラボン合成酵素をコードする遺伝子 |
| AUPS017402A0 (en) * | 2002-01-25 | 2002-02-14 | International Flower Developments Pty Ltd | Genetic sequences and uses therefor |
| KR100440332B1 (ko) * | 2002-06-28 | 2004-07-15 | 현대자동차주식회사 | 유압 회로용 투웨이 오리피스 첵밸브 장치 |
| US7612257B2 (en) * | 2002-08-30 | 2009-11-03 | International Flower Developments Pty. Ltd. | Flavonoid 3′,5′ hydroxylase gene sequences and uses therefor |
| JP4378676B2 (ja) * | 2003-06-03 | 2009-12-09 | 日本電気株式会社 | 電力制御方法および電力制御回路 |
| CN1836039B (zh) | 2003-08-13 | 2010-05-26 | 国际花卉开发有限公司 | 改变了花色的蔷薇的制造方法 |
| JPWO2008156214A1 (ja) * | 2007-06-20 | 2010-08-26 | インターナショナル フラワー ディベロプメンツ プロプライアタリー リミティド | フラボン及びデルフィニジンを含むバラ及びその生産方法 |
-
2008
- 2008-06-19 EP EP08777606A patent/EP2163619B1/en not_active Not-in-force
- 2008-06-19 ES ES08777606T patent/ES2385416T3/es active Active
- 2008-06-19 TW TW097122851A patent/TWI440430B/zh not_active IP Right Cessation
- 2008-06-19 BR BRPI0813127A patent/BRPI0813127A8/pt not_active Application Discontinuation
- 2008-06-19 WO PCT/JP2008/061593 patent/WO2008156206A1/ja not_active Ceased
- 2008-06-19 AU AU2008264434A patent/AU2008264434B2/en not_active Ceased
- 2008-06-19 JP JP2009520624A patent/JP5057349B2/ja active Active
- 2008-06-19 CN CN2008800209289A patent/CN101679972B/zh active Active
- 2008-06-19 RU RU2010101626/10A patent/RU2463348C2/ru active
- 2008-06-19 US US12/664,998 patent/US20100281575A1/en not_active Abandoned
- 2008-06-19 KR KR1020097027554A patent/KR101168421B1/ko not_active Expired - Fee Related
- 2008-06-19 CA CA2690754A patent/CA2690754C/en active Active
-
2009
- 2009-12-17 IL IL202818A patent/IL202818A/en active IP Right Grant
- 2009-12-18 CO CO09145330A patent/CO6170374A2/es active IP Right Grant
- 2009-12-18 EC EC2009009814A patent/ECSP099814A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TWI440430B (zh) | 2014-06-11 |
| ES2385416T3 (es) | 2012-07-24 |
| IL202818A0 (en) | 2011-08-01 |
| EP2163619A4 (en) | 2010-11-03 |
| IL202818A (en) | 2015-08-31 |
| WO2008156206A1 (ja) | 2008-12-24 |
| KR20100017986A (ko) | 2010-02-16 |
| AU2008264434B2 (en) | 2012-03-08 |
| EP2163619B1 (en) | 2012-05-16 |
| US20100281575A1 (en) | 2010-11-04 |
| EP2163619A1 (en) | 2010-03-17 |
| CO6170374A2 (es) | 2010-06-18 |
| RU2463348C2 (ru) | 2012-10-10 |
| JP5057349B2 (ja) | 2012-10-24 |
| KR101168421B1 (ko) | 2012-07-25 |
| TW200911109A (en) | 2009-03-16 |
| CN101679972A (zh) | 2010-03-24 |
| RU2010101626A (ru) | 2011-07-27 |
| BRPI0813127A2 (pt) | 2014-10-14 |
| CA2690754C (en) | 2014-09-23 |
| CN101679972B (zh) | 2013-09-04 |
| AU2008264434A1 (en) | 2008-12-24 |
| JPWO2008156206A1 (ja) | 2010-08-26 |
| CA2690754A1 (en) | 2008-12-24 |
| ECSP099814A (es) | 2010-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: SUNTORY HOLDINGS LIMITED (JP) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |