BRPI0812865A2 - Derivados de 6-anilinopurina substituída como inibidores de citoquinina oxidase/desidrogenase e preparações contendo esses derivados. - Google Patents

Derivados de 6-anilinopurina substituída como inibidores de citoquinina oxidase/desidrogenase e preparações contendo esses derivados.

Info

Publication number: BRPI0812865A2
Authority: BR; Brazil
Prior art keywords: derivatives; anylinopurine; cytokinine; oxidase; preparations containing
Prior art date: 2007-07-04

Application number

BRPI0812865-0A2A

Other languages

English (en)

Inventor

Lukas Spichal

Marketa Gemrotova

Marek Zatloukal

Jitka Frebortova

Petr Galuszka

Tomas Werner

Thomas Schmulling

Karel Dolezal

Miroslav Strnad

Original Assignee

Univ Berlin Freie

Univerzita Palackecho V Olomouci

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-07-04

Filing date

2008-07-02

Publication date

2014-10-07

2008-07-02 Application filed by Univ Berlin Freie, Univerzita Palackecho V Olomouci filed Critical Univ Berlin Freie

2014-10-07 Publication of BRPI0812865A2 publication Critical patent/BRPI0812865A2/pt

2019-09-03 Publication of BRPI0812865B1 publication Critical patent/BRPI0812865B1/pt

2022-09-20 Publication of BRPI0812865B8 publication Critical patent/BRPI0812865B8/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Wood Science & Technology (AREA)
Agronomy & Crop Science (AREA)
Pest Control & Pesticides (AREA)
Plant Pathology (AREA)
Dentistry (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Dermatology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

BRPI0812865A 2007-07-04 2008-07-02 derivados de 6-anilinopurina substituída BRPI0812865B8 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CZ20070453A CZ302225B6 (cs)	2007-07-04	2007-07-04	Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny
PCT/CZ2008/000074 WO2009003428A2 (en)	2007-07-04	2008-07-02	Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase/dehydrogenase and preparations containing these derivatives

Publications (3)

Publication Number	Publication Date
BRPI0812865A2 true BRPI0812865A2 (pt)	2014-10-07
BRPI0812865B1 BRPI0812865B1 (pt)	2019-09-03
BRPI0812865B8 BRPI0812865B8 (pt)	2022-09-20

Family

ID=40226563

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0812865A BRPI0812865B8 (pt)	2007-07-04	2008-07-02	derivados de 6-anilinopurina substituída

Country Status (13)

Country	Link
US (1)	US8222260B2 (pt)
EP (1)	EP2173173B1 (pt)
JP (1)	JP5539866B2 (pt)
AU (1)	AU2008271800B2 (pt)
BR (1)	BRPI0812865B8 (pt)
CA (1)	CA2691625C (pt)
CZ (1)	CZ302225B6 (pt)
DK (1)	DK2173173T3 (pt)
ES (1)	ES2431926T3 (pt)
NZ (1)	NZ582642A (pt)
PL (1)	PL2173173T3 (pt)
PT (1)	PT2173173E (pt)
WO (1)	WO2009003428A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2351487A4 (en) *	2008-10-20	2012-09-05	Kumiai Chemical Industry Co	GROWTH REGULATOR FOR ADVENTIAL GRASSES
CZ306894B6 (cs)	2013-02-08	2017-08-30	Univerzita PalackĂ©ho v Olomouci	2-Substituované-6-biarylmethylamino-9-cyklopentyl-9H-purinové deriváty, jejich použití jako léčiva a farmaceutické přípravky tyto sloučeniny obsahující
US9938279B2 (en) *	2013-04-09	2018-04-10	Energenesis Biomedical Co., Ltd	Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)
ES2975192T3 (es)	2013-12-11	2024-07-03	Fine Agrochemicals Ltd	Concentrado para la regulación del crecimiento de plantas dispersable en agua y procesos para fabricar y usar el mismo
US10662194B2 (en)	2014-12-15	2020-05-26	Univerzita Palackeho V Olomouci	Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress
ITUB20153115A1 (it) *	2015-08-13	2017-02-13	Diapath S P A	Nuova composizione fissativa per campioni di materiale biologico.
GB201610264D0 (en) *	2016-06-13	2016-07-27	Syngenta Participations Ag	Pesticidal compositions
CN109310092B (zh) *	2016-06-14	2021-12-24	先正达参股股份有限公司	6-苯胺嘌呤衍生物用于提高稻秧的热胁迫耐受性的用途
JP7037508B2 (ja) *	2016-06-14	2022-03-16	シンジェンタパーティシペーションズアーゲー	非生物的ストレス耐性
CN110300590A (zh)	2016-10-21	2019-10-01	林伯士拉克许米公司	Tyk2抑制剂及其用途
WO2018217884A1 (en)	2017-05-23	2018-11-29	Regents Of The University Of Minnesota	Antibacterial agents including histidine kinase inhibitors
CU20200050A7 (es) *	2017-12-12	2021-03-11	Syngenta Participations Ag	Composición combinada de 2-fluoro-n-(3-metoxifenil)-9h-purin-6-amina y trinexapac-etilo útil en la regulación del crecimiento de plantas
CN108371662B (zh) *	2018-02-06	2023-03-03	中国药科大学	一种五元杂环并嘧啶类化合物的应用
CN110407836B (zh) *	2019-08-15	2022-03-29	沈阳化工研究院有限公司	一种9-（2-甲氧基乙基）-9h-嘌呤-6-胺衍生物及其应用
CN110642859B (zh) *	2019-10-11	2021-11-09	青岛科技大学	一种含嘧啶硫酮嘌呤类化合物及其用途
CZ309368B6 (cs) *	2020-05-17	2022-10-12	Univerzita Palackého v Olomouci	Mesylátové soli heterocyklických cytokininů, přípravky obsahující tyto deriváty a jejich použití
WO2022012702A1 (en)	2020-07-13	2022-01-20	Univerzita Palackeho V Olomouci	Nitrogen heterocyclic cytokinin derivatives, compositions containing these derivatives and use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3118753A (en) *	1961-04-14	1964-01-21	Shive William	Plant growth stimulating composition and method employing mixtures of a gibberellic acid and purine compound
EP0155911A1 (de) *	1984-03-19	1985-09-25	Ciba-Geigy Ag	Purinderivate zur Regulierung des Pflanzenwachstums
DE69131692T3 (de) *	1991-05-16	2004-09-23	Senetek, Plc	Verfahren und zusammensetzung zur verbesserung der ungünstigen auswirkungen des alterns
WO1993014103A1 (en) *	1992-01-06	1993-07-22	The Wellcome Foundation Limited	Therapeutic nucleosides
BR9611157A (pt) *	1995-11-01	1999-03-30	Novartis Ag	Derivados de purina e processos para sua preparação
EA001470B1 (ru)	1996-03-15	2001-04-23	Новартис Аг	Синергетическая гербицидная композиция и способ борьбы с сорняками
CZ294535B6 (cs) *	2001-08-02	2005-01-12	Ústav Experimentální Botaniky Avčr	Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
US20070161582A1 (en) *	2003-08-08	2007-07-12	Dusan Mijikovic	Pharmaceutical compositions and methods for metabolic modulation
JP2007502776A (ja) *	2003-08-15	2007-02-15	アイアールエム・リミテッド・ライアビリティ・カンパニー	Ｒｔｋ阻害剤としての６−置換アニリノプリン類
GB0407723D0 (en) *	2004-04-05	2004-05-12	Novartis Ag	Organic compounds

2007
- 2007-07-04 CZ CZ20070453A patent/CZ302225B6/cs unknown
2008
- 2008-07-02 CA CA2691625A patent/CA2691625C/en active Active
- 2008-07-02 DK DK08773244.2T patent/DK2173173T3/da active
- 2008-07-02 EP EP08773244.2A patent/EP2173173B1/en active Active
- 2008-07-02 JP JP2010513636A patent/JP5539866B2/ja active Active
- 2008-07-02 PT PT87732442T patent/PT2173173E/pt unknown
- 2008-07-02 US US12/666,189 patent/US8222260B2/en active Active
- 2008-07-02 WO PCT/CZ2008/000074 patent/WO2009003428A2/en not_active Ceased
- 2008-07-02 ES ES08773244T patent/ES2431926T3/es active Active
- 2008-07-02 PL PL08773244T patent/PL2173173T3/pl unknown
- 2008-07-02 NZ NZ582642A patent/NZ582642A/en unknown
- 2008-07-02 AU AU2008271800A patent/AU2008271800B2/en active Active
- 2008-07-02 BR BRPI0812865A patent/BRPI0812865B8/pt active IP Right Grant

Also Published As

Publication number	Publication date
ES2431926T3 (es)	2013-11-28
EP2173173A2 (en)	2010-04-14
WO2009003428A3 (en)	2009-09-03
BRPI0812865B8 (pt)	2022-09-20
WO2009003428A2 (en)	2009-01-08
AU2008271800B2 (en)	2013-10-17
CZ2007453A3 (cs)	2009-02-11
AU2008271800A1 (en)	2009-01-08
PL2173173T3 (pl)	2014-07-31
PT2173173E (pt)	2013-10-22
EP2173173B1 (en)	2013-07-24
CA2691625C (en)	2014-12-09
BRPI0812865B1 (pt)	2019-09-03
CA2691625A1 (en)	2009-01-08
JP2010531818A (ja)	2010-09-30
DK2173173T3 (da)	2013-11-04
US20100190806A1 (en)	2010-07-29
CZ302225B6 (cs)	2010-12-29
US8222260B2 (en)	2012-07-17
NZ582642A (en)	2011-06-30
JP5539866B2 (ja)	2014-07-02

Publication	Publication Date	Title
BRPI0812865A2 (pt)	2014-10-07	Derivados de 6-anilinopurina substituída como inibidores de citoquinina oxidase/desidrogenase e preparações contendo esses derivados.
LTPA2018510I1 (lt)	2018-09-25	Dioksa-biciklo[3.2.1]oktan-2,3,4-triolio dariniai
BRPI1015568A2 (pt)	2016-08-16	derivados de imidazolidin-2-ona 1,3-dissubstituído como inibidores de cyp 17.
GT200900014A (es)	2010-02-09	Derivados de i-(-d-glucopiranosil)-3-(4-ciclopropilfenilmetil)-4-halogeno indoly uso de los mismos como inhibidores de los transportadores de glucosa dependientes de sodio.
BRPI0718266A2 (pt)	2014-01-07	Compostos heterocíclicos como agentes anti-inflamatórios.
IL210195A0 (en)	2011-03-31	Benzoxazines, benzothazines, and related compounds having nos inhibitory activity
DK2545918T3 (da)	2014-11-10	Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer
SMAP201000115A (it)	2011-01-19	Nuovi composti eterociclici e loro usi.
MX2009004883A (es)	2009-05-21	Piridil sulfoximinas multi-substituidas y su uso como insecticidas.
BRPI1016150A2 (pt)	2016-04-19	compostos heterocíclicos e seus usos.
IL211889A (en)	2016-07-31	Pyrazolo pyridine derivatives, preparations containing them and their use as nadph oxidase inhibitors
BRPI0919328A2 (pt)	2015-12-29	derivados de pirazolo piridina como inibidores de nadph oxidase
WO2011084803A3 (en)	2011-11-24	Coloring agents and methods of use thereof
BR112013013790A2 (pt)	2016-09-13	compostos heterocíclos nitrogenosos 6,6-fundidos substituídos e usos dos mesmos
EP2183363A4 (en)	2010-12-29	NEW MUSHROOM CYMS
BRPI1015967A2 (pt)	2016-06-14	"unidade de dobradiça, e, peça de mobília."
BRPI1016117A8 (pt)	2018-01-02	derivados de isoxazol-isoxazol e isoxazol-isotiazol.
BRPI0807897A2 (pt)	2014-06-17	Derivados de pirimidina-2,4-diamina e seus usos como inibidores de jak2 quinase.
DK2108260T3 (da)	2013-07-08	Sammensætning med biocid aktivitet til vandige præparater
ATE545417T1 (de)	2012-03-15	Pyrazoloä3,4-büpyridin-derivate als phosphodiesterasehemmer
BRPI0917446A2 (pt)	2015-12-22	derivados de acilaminobenzamida.
DK2344486T3 (da)	2013-07-08	Alkylthiazolcarbamatderivater, fremstilling deraf og anvendelse deraf som hæmmere af enzymet FAAH
WO2011115809A3 (en)	2012-01-19	High energy radiation insensitive analyte sensors
BRPI0914584A2 (pt)	2015-08-04	Método, e, composição herbicida.
FR2932959B1 (fr)	2010-08-13	Piece protectrice contre le transfert de secretions corporelles.

Legal Events

Date	Code	Title	Description
2015-11-17	B25A	Requested transfer of rights approved	Owner name: UNIVERZITA PALACKECHO V OLOMOUCI (CZ)
2015-12-08	B25A	Requested transfer of rights approved	Owner name: SYNGENTA PARTICIPATIONS AG (CH)
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-02-12	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-04-16	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2019-08-06	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2019-09-03	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS
2021-05-25	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/07/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF
2021-08-24	B15V	Prolongation of time limit allowed
2022-05-03	B22E	Other requirements [chapter 22.5 patent gazette]	Free format text: FORMULADA EXIGENCIA PARA ADEQUACAO OU CUMPRIMENTO DE DISPOSICOES LEGAIS NO PRAZO DE 60 (SESSENTA) DIAS DESTA DATA.
2022-09-13	B16B	Notification of grant cancelled [chapter 16.2 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 16.3 NA RPI NO 2629 DE 25/05/2021 POR TER SIDO INDEVIDA.
2022-09-20	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: RETIFICACAO REF. RPI 2539, DE 03/09/2019. PRAZO DE VALIDADE: 10 ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME A ADI 5.529/DF, COM APOSTILAMENTO DO PRAZO DE VALIDADE DA PROTECAO DA MATERIA RELATIVA A PRODUTOS E PROCESSOS FARMACEUTICOS E EQUIPAMENTOS E/OU MATERIAIS DE USO EM SAUDE, PARA APLICACAO EM HUMANOS.
2025-07-29	B25A	Requested transfer of rights approved	Owner name: SYNGENTA CROP PROTECTION AG (CH)