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BRPI0812185B8 - new compounds - Google Patents

new compounds

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Publication number
BRPI0812185B8
BRPI0812185B8 BRPI0812185A BRPI0812185A BRPI0812185B8 BR PI0812185 B8 BRPI0812185 B8 BR PI0812185B8 BR PI0812185 A BRPI0812185 A BR PI0812185A BR PI0812185 A BRPI0812185 A BR PI0812185A BR PI0812185 B8 BRPI0812185 B8 BR PI0812185B8
Authority
BR
Brazil
Prior art keywords
compounds
formula
preparation
metabolic syndrome
new compounds
Prior art date
Application number
BRPI0812185A
Other languages
Portuguese (pt)
Inventor
Kasundra Ashok
Dutt C
Tuli Davinder
Chhipa Laxmikant
Amir Siddiqui M
Gupta Ramesh
Munshi Siralee
Pukharaj Zambad Shitalkumar
Bhattamisra Subrat
Chauthaiwale Vijay
Original Assignee
Torrent Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd filed Critical Torrent Pharmaceuticals Ltd
Priority claimed from PCT/IN2008/000345 external-priority patent/WO2008149379A2/en
Publication of BRPI0812185A2 publication Critical patent/BRPI0812185A2/en
Publication of BRPI0812185B1 publication Critical patent/BRPI0812185B1/en
Publication of BRPI0812185B8 publication Critical patent/BRPI0812185B8/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

novos compostos. a presente invenção divulga novos compostos semelhantes à tireóide de fórmula (i), em que r1, r2, r2, r4 e z são conforme definido na especificação, um método para seu preparo, composição contendo tais compostos e uso de tais compostos e da composição como medicamento. ainda, compostos de fórmula (i) têm afinidade de ligação significativamente baixa por receptores de tiróide e, assim, são consideravelmente desprovidos de efeitos tirotóxicos. a invenção também se refere ao uso do composto de fórmula (i) para o preparo de um medicamento para tratamento de várias condições doentias, tais como obesidade, dislipidemia, síndrome metabólica e comorbidades associadas à síndrome metabólica.new compounds. the present invention discloses novel thyroid-like compounds of formula (I), wherein r1, r2, r2, r4 and z are as defined in the specification, a method for their preparation, composition containing such compounds and use of such compounds and the composition as medicine. furthermore, compounds of formula (I) have significantly low binding affinity for thyroid receptors and thus are considerably devoid of thyrotoxic effects. the invention also relates to the use of the compound of formula (I) for the preparation of a medicament for treating various disease conditions such as obesity, dyslipidemia, metabolic syndrome and comorbidities associated with metabolic syndrome.

BRPI0812185A 2007-06-06 2008-06-02 new compounds BRPI0812185B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN875/KOL/2007 2007-06-06
IN875KO2007 2007-06-06
PCT/IN2008/000345 WO2008149379A2 (en) 2007-06-06 2008-06-02 Novel compounds

Publications (3)

Publication Number Publication Date
BRPI0812185A2 BRPI0812185A2 (en) 2015-08-11
BRPI0812185B1 BRPI0812185B1 (en) 2019-09-17
BRPI0812185B8 true BRPI0812185B8 (en) 2021-05-25

Family

ID=53801759

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812185A BRPI0812185B8 (en) 2007-06-06 2008-06-02 new compounds

Country Status (1)

Country Link
BR (1) BRPI0812185B8 (en)

Also Published As

Publication number Publication date
BRPI0812185A2 (en) 2015-08-11
BRPI0812185B1 (en) 2019-09-17

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Legal Events

Date Code Title Description
B08E Application fees: payment of additional fee required [chapter 8.5 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/09/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/09/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/06/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 16A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2777 DE 26-03-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.