BRPI0810309A2 - "peptide, chimeric polypeptide, isolated nucleic acid molecules, vector, infectious viral particle, host cell, pharmaceutical composition, uses of a chimeric polypeptide, a nucleic acid molecule, a vector, an infectious viral particle, a host cell and peptides methods for recombinantly producing a polypeptide, for directing expression of a polypeptide of interest and for directing expression of a polypeptide. - Google Patents
"peptide, chimeric polypeptide, isolated nucleic acid molecules, vector, infectious viral particle, host cell, pharmaceutical composition, uses of a chimeric polypeptide, a nucleic acid molecule, a vector, an infectious viral particle, a host cell and peptides methods for recombinantly producing a polypeptide, for directing expression of a polypeptide of interest and for directing expression of a polypeptide.Info
- Publication number
- BRPI0810309A2 BRPI0810309A2 BRPI0810309A BRPI0810309A BRPI0810309A2 BR PI0810309 A2 BRPI0810309 A2 BR PI0810309A2 BR PI0810309 A BRPI0810309 A BR PI0810309A BR PI0810309 A BRPI0810309 A BR PI0810309A BR PI0810309 A2 BRPI0810309 A2 BR PI0810309A2
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- nucleic acid
- vector
- host cell
- infectious viral
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 23
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 20
- 229920001184 polypeptide Polymers 0.000 title abstract 15
- 208000015181 infectious disease Diseases 0.000 title abstract 5
- 230000002458 infectious effect Effects 0.000 title abstract 5
- 102000039446 nucleic acids Human genes 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 5
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 239000002245 particle Substances 0.000 title abstract 5
- 239000013598 vector Substances 0.000 title abstract 5
- 230000003612 virological effect Effects 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- -1 host cell Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 3
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 1
- 238000004873 anchoring Methods 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 108091006116 chimeric peptides Proteins 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
Landscapes
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
peptídeo, polipeptídeo quimérico, moléculas de ácido nucleico isoladas, vetor, partícula viral infecciosa, célula hospedeira, composição farmacêutica, usos de um polipeptídeo quimérico, uma molécula de ácido nucleico, um vetor, uma partícula viral infecciosa, uma célula hospedeira e de peptídeos, métodos para produzir de forma recombinante um polipeptídeo, para direcionar a expressão de um polipeptídeo de interesse e para direcionar a expressão de um polipeptídeo a presente invenção fornece novos peptídeos de sequência especificada e sua utilizção como um peptídeo sinal ou peptídeo de ancoragem à membrana. também refere-se a polipeptídeos quiméricos compreendendo um ou mais destes peptídeos e um polipeptídeo de interesse, bem como moléculas de ácido nucleico, vetores, partículas virais infecciosas e células hospedeiras que codificam tais peptídeos e polipeptídeos quiméricos. a presente invenção também se refere a uma composição farmacêutica compreendendo tais elementos e um veículo farmaceuticamente aceitável. a presente invenção também fornece um método para produzir um polipeptídeo recombinante utilizando tais peptídeos, especialmente para direcionar extracelularmente a expressão de um polipeptídeo de interesse ou torná-lo ancorado na superfície da membrana plasmática.peptide, chimeric polypeptide, isolated nucleic acid molecules, vector, infectious viral particle, host cell, pharmaceutical composition, uses of a chimeric polypeptide, a nucleic acid molecule, a vector, an infectious viral particle, a host cell and peptides, Methods for Recombinantly Producing a Polypeptide, for Directing Expression of a Polypeptide of Interest and for Directing Expression of a Polypeptide The present invention provides novel peptides of specified sequence and their use as a signal peptide or membrane anchor peptide. also refers to chimeric polypeptides comprising one or more of these peptides and a polypeptide of interest, as well as nucleic acid molecules, vectors, infectious viral particles and host cells encoding such chimeric peptides and polypeptides. The present invention also relates to a pharmaceutical composition comprising such elements and a pharmaceutically acceptable carrier. The present invention also provides a method for producing a recombinant polypeptide using such peptides, especially for extracellularly directing expression of a polypeptide of interest or anchoring it to the surface of the plasma membrane.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP73600207 | 2007-05-15 | ||
| PCT/EP2008/051035 WO2008138649A2 (en) | 2007-05-15 | 2008-01-29 | Signaling peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0810309A2 true BRPI0810309A2 (en) | 2019-07-30 |
Family
ID=67432469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0810309A BRPI0810309A2 (en) | 2007-05-15 | 2008-01-29 | "peptide, chimeric polypeptide, isolated nucleic acid molecules, vector, infectious viral particle, host cell, pharmaceutical composition, uses of a chimeric polypeptide, a nucleic acid molecule, a vector, an infectious viral particle, a host cell and peptides methods for recombinantly producing a polypeptide, for directing expression of a polypeptide of interest and for directing expression of a polypeptide. |
Country Status (1)
| Country | Link |
|---|---|
| BR (1) | BRPI0810309A2 (en) |
-
2008
- 2008-01-29 BR BRPI0810309A patent/BRPI0810309A2/en not_active IP Right Cessation
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2535 DE 06-08-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] |