BRPI0819902A2 - C2-c5-alquil-imidazol-bifosfonatos - Google Patents

C2-c5-alquil-imidazol-bifosfonatos

Info

Publication number: BRPI0819902A2
Authority: BR; Brazil
Prior art keywords: bisphosphonates; alkyl imidazole; imidazole; alkyl; imidazole bisphosphonates
Prior art date: 2007-11-30

Application number

BRPI0819902-7A

Other languages

English (en)

Inventor

Sven Weiler

Leo Widler

Jean-Michel Rondeau

Simona Cotesta

Wolfgang Jahnke

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-11-30

Filing date

2008-11-26

Publication date

2015-05-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39154111&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0819902(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-11-26 Application filed by Novartis Ag filed Critical Novartis Ag

2015-05-19 Publication of BRPI0819902A2 publication Critical patent/BRPI0819902A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Physical Education & Sports Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI0819902-7A 2007-11-30 2008-11-26 C2-c5-alquil-imidazol-bifosfonatos BRPI0819902A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07122016		2007-11-30
PCT/EP2008/066245 WO2009068567A1 (en)	2007-11-30	2008-11-26	C2-c5-alkyl-imidazole-bisphosphonates

Publications (1)

Publication Number	Publication Date
BRPI0819902A2 true BRPI0819902A2 (pt)	2015-05-19

Family

ID=39154111

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0819902-7A BRPI0819902A2 (pt)	2007-11-30	2008-11-26	C2-c5-alquil-imidazol-bifosfonatos

Country Status (24)

Country	Link
US (2)	US7977323B2 (pt)
EP (1)	EP2225252B1 (pt)
JP (1)	JP5244917B2 (pt)
KR (1)	KR20100092035A (pt)
CN (1)	CN101835787A (pt)
AR (1)	AR069437A1 (pt)
AU (1)	AU2008328797B2 (pt)
BR (1)	BRPI0819902A2 (pt)
CA (1)	CA2701516A1 (pt)
CL (1)	CL2008003545A1 (pt)
CO (1)	CO6280421A2 (pt)
CR (1)	CR11362A (pt)
EA (1)	EA201000860A1 (pt)
EC (1)	ECSP10010321A (pt)
ES (1)	ES2386851T3 (pt)
IL (1)	IL204657A0 (pt)
MA (1)	MA31895B1 (pt)
MX (1)	MX2010005786A (pt)
NZ (1)	NZ584219A (pt)
PE (1)	PE20091038A1 (pt)
TN (1)	TN2010000138A1 (pt)
TW (1)	TW200932248A (pt)
WO (1)	WO2009068567A1 (pt)
ZA (1)	ZA201001992B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20110005837A (ko) *	2008-04-04	2011-01-19	노파르티스 아게	비스포스포네이트를 갖는 제약 조성물
US9169279B2 (en)	2009-07-31	2015-10-27	Thar Pharmaceuticals, Inc.	Crystallization method and bioavailability
US20160016982A1 (en)	2009-07-31	2016-01-21	Thar Pharmaceuticals, Inc.	Crystallization method and bioavailability
AU2010278860B2 (en)	2009-07-31	2016-05-26	Thar Pharma, Llc	Crystallization method and bioavailability
WO2011147038A1 (en)	2010-05-28	2011-12-01	The Royal Institution For The Advancement Of Learning/Mcgill University	Heterocyclyl-pyridinyl-based biphosphonic acid, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof
US9290526B2 (en)	2010-05-28	2016-03-22	The Royal Institution For The Advancement Of Learning/Mcgill University	Heterocyclyl-pyridinyl-based biphosphonic acid, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof
US9340565B2 (en)	2010-11-24	2016-05-17	Thar Pharmaceuticals, Inc.	Crystalline forms
CN102659840B (zh) *	2012-05-10	2013-08-14	苏州普瑞诺药物技术有限公司	咪唑双膦酸类化合物及其可药用盐及药物用途
US10195218B2 (en)	2016-05-31	2019-02-05	Grunenthal Gmbh	Crystallization method and bioavailability
KR20200066690A (ko)	2017-10-16	2020-06-10	칭화대학교	메발로네이트 경로 억제제 및 이의 약제학적 조성물
CN112980809B (zh) *	2021-03-17	2023-04-11	云南中烟工业有限责任公司	一种烟草法尼基焦磷酸合酶基因及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10199052I1 (de)	1986-11-21	2002-01-10	Novartis Ag	Neue substituierte Alkandiphosphonsaeuren
EP0573604B1 (en) *	1991-02-26	1995-03-15	PROCTER & GAMBLE PHARMACEUTICALS, INC. (an Ohio corp.)	Methods for the treatment of osteoporosis
GB9324143D0 (en)	1993-11-24	1994-01-12	Schering Agrochemicals Ltd	Triazole phosphonate pesticides
GB0029018D0 (en) *	2000-11-28	2001-01-10	Strakan Group Plc	Dermatological formulations
GB0029111D0 (en)	2000-11-29	2001-01-10	Novartis Ag	Organic compounds
WO2006039721A2 (en)	2004-10-08	2006-04-13	The Board Of Trustees Of The University Of Illinois	Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases
US8012949B2 (en)	2004-10-08	2011-09-06	The Board Of Trustees Of The University Of Illinois	Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS
WO2008040763A1 (en)	2006-10-05	2008-04-10	Novartis Ag	Pharmaceutical compositions comprising bisphosphonates
EP2139888A2 (en)	2007-03-28	2010-01-06	Array Biopharma, Inc.	Imidazoý1,2-a¨pyridine compounds as receptor tyrosine kinase inhibitors

2008
- 2008-11-26 EP EP08854485A patent/EP2225252B1/en active Active
- 2008-11-26 MX MX2010005786A patent/MX2010005786A/es active IP Right Grant
- 2008-11-26 NZ NZ584219A patent/NZ584219A/en not_active IP Right Cessation
- 2008-11-26 ES ES08854485T patent/ES2386851T3/es active Active
- 2008-11-26 CA CA2701516A patent/CA2701516A1/en not_active Abandoned
- 2008-11-26 EA EA201000860A patent/EA201000860A1/ru unknown
- 2008-11-26 WO PCT/EP2008/066245 patent/WO2009068567A1/en not_active Ceased
- 2008-11-26 BR BRPI0819902-7A patent/BRPI0819902A2/pt not_active IP Right Cessation
- 2008-11-26 JP JP2010535369A patent/JP5244917B2/ja active Active
- 2008-11-26 US US12/323,696 patent/US7977323B2/en not_active Expired - Fee Related
- 2008-11-26 KR KR1020107014395A patent/KR20100092035A/ko not_active Ceased
- 2008-11-26 AU AU2008328797A patent/AU2008328797B2/en not_active Ceased
- 2008-11-26 CN CN200880112351A patent/CN101835787A/zh active Pending
- 2008-11-27 AR ARP080105163A patent/AR069437A1/es active IP Right Grant
- 2008-11-27 PE PE2008001990A patent/PE20091038A1/es not_active Application Discontinuation
- 2008-11-28 CL CL2008003545A patent/CL2008003545A1/es unknown
- 2008-11-28 TW TW097146484A patent/TW200932248A/zh unknown
2010
- 2010-03-19 ZA ZA2010/01992A patent/ZA201001992B/en unknown
- 2010-03-22 IL IL204657A patent/IL204657A0/en unknown
- 2010-03-26 TN TNP2010000138A patent/TN2010000138A1/fr unknown
- 2010-04-09 CR CR11362A patent/CR11362A/es unknown
- 2010-05-26 CO CO10063351A patent/CO6280421A2/es not_active Application Discontinuation
- 2010-05-31 MA MA32880A patent/MA31895B1/fr unknown
- 2010-06-30 EC EC2010010321A patent/ECSP10010321A/es unknown
2011
- 2011-05-26 US US13/116,671 patent/US20110224173A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2011504908A (ja)	2011-02-17
AU2008328797B2 (en)	2011-11-03
KR20100092035A (ko)	2010-08-19
AR069437A1 (es)	2010-01-20
US20090143337A1 (en)	2009-06-04
TN2010000138A1 (en)	2011-09-26
TW200932248A (en)	2009-08-01
NZ584219A (en)	2012-03-30
PE20091038A1 (es)	2009-08-19
CA2701516A1 (en)	2009-06-04
ECSP10010321A (es)	2010-08-31
EA201000860A1 (ru)	2010-12-30
CR11362A (es)	2010-06-14
ZA201001992B (en)	2010-12-29
US7977323B2 (en)	2011-07-12
ES2386851T3 (es)	2012-09-03
CN101835787A (zh)	2010-09-15
EP2225252A1 (en)	2010-09-08
US20110224173A1 (en)	2011-09-15
CL2008003545A1 (es)	2009-06-05
MX2010005786A (es)	2010-06-09
JP5244917B2 (ja)	2013-07-24
CO6280421A2 (es)	2011-05-20
EP2225252B1 (en)	2012-06-27
WO2009068567A1 (en)	2009-06-04
MA31895B1 (fr)	2010-12-01
AU2008328797A1 (en)	2009-06-04
IL204657A0 (en)	2010-11-30

Publication	Publication Date	Title
BRPI0819902A2 (pt)	2015-05-19	C2-c5-alquil-imidazol-bifosfonatos
BRPI0922904A2 (pt)	2018-05-29	"compostos"
FR17C1014I2 (fr)	2018-05-04	Compositions fongicides
BRPI0910229A2 (pt)	2015-09-01	Tetramatos de 4';4'-dioxaspiro espirociclicamente substituídos
BRPI1015540A2 (pt)	2019-09-24	''composto de 1-cianoetil-heterociclilcarboxamida substituídos 750''
EP2280916A4 (en)	2014-07-23	HYDROCHLORFLUOROLEFINZUSAMMENSETZUNGEN
BRPI0914746A2 (pt)	2019-09-24	composições fungicidas
ATE502948T1 (de)	2011-04-15	Substituierte bicyclolactamverbindungen
BRPI1007878A2 (pt)	2015-09-01	"compostos inseticidas"
EP2183614A4 (en)	2011-03-16	DISTANCE ESTIMATING
ATE554776T1 (de)	2012-05-15	Antivirale phosphinatverbindungen
BRPI0914533A2 (pt)	2015-12-15	"métodos"
BRPI0914759A2 (pt)	2015-10-20	derivado de alquil pirimidin-4-ona substituída
DK2308869T3 (da)	2012-10-08	Azolforbindelse
BRPI0811433A2 (pt)	2016-03-22	compostos do tipo triazolil aminopirimidina
EP2208972A4 (en)	2011-06-01	COMBINATION SCALE
BRPI0720097A2 (pt)	2014-10-07	Compostos de fosfonato
EP2258697A4 (en)	2011-08-03	HYDROXYCHINOXALINCARBOXAMIDDERIVAT
EP2537831A4 (en)	2013-09-04	imidazole
EP2344503A4 (en)	2012-07-11	5-azaindole bisphosphonates
MA30860B1 (fr)	2009-11-02	Myrtillier denomme "c97-390"
BRPI0811860A2 (pt)	2014-11-18	Compostos de (fenil)imidazolil)metilheteroarila
BRPI0924887A2 (pt)	2015-07-07	Compostos de fenilalquil-imidazol-bifosfonato
FR2936764B1 (fr)	2010-11-05	Couloir d'intercirculation
ES1068308Y (es)	2009-01-01	Zapatilla de baño

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.