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BRPI0819056A2 - "processo para a preparação de 5-(2-etil-diidro-1h-inden-2-il)-1h-imidazol e seus sais" - Google Patents

"processo para a preparação de 5-(2-etil-diidro-1h-inden-2-il)-1h-imidazol e seus sais"

Info

Publication number
BRPI0819056A2
BRPI0819056A2 BRPI0819056A BRPI0819056A2 BR PI0819056 A2 BRPI0819056 A2 BR PI0819056A2 BR PI0819056 A BRPI0819056 A BR PI0819056A BR PI0819056 A2 BRPI0819056 A2 BR PI0819056A2
Authority
BR
Brazil
Prior art keywords
inden
dihydro
imidazole
salts
ethyl
Prior art date
Application number
Other languages
English (en)
Inventor
Viesturs Lusis
Dzintra Muceniece
Inese Reine
Armands Zandersons
Original Assignee
Grindeks Jsc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grindeks Jsc filed Critical Grindeks Jsc
Publication of BRPI0819056A2 publication Critical patent/BRPI0819056A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
BRPI0819056 2007-12-05 2008-12-03 "processo para a preparação de 5-(2-etil-diidro-1h-inden-2-il)-1h-imidazol e seus sais" BRPI0819056A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07122400 2007-12-05
PCT/EP2008/066709 WO2009071584A1 (en) 2007-12-05 2008-12-03 Process for the preparation of 5-(2-ethyl-dihydro-1h-inden-2-yl)-1h-imidazole and salts thereof

Publications (1)

Publication Number Publication Date
BRPI0819056A2 true BRPI0819056A2 (pt) 2015-05-05

Family

ID=39092917

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819056 BRPI0819056A2 (pt) 2007-12-05 2008-12-03 "processo para a preparação de 5-(2-etil-diidro-1h-inden-2-il)-1h-imidazol e seus sais"

Country Status (15)

Country Link
US (1) US8431717B2 (pt)
EP (1) EP2225209B1 (pt)
JP (1) JP2011506284A (pt)
KR (1) KR20100086029A (pt)
CN (1) CN101889003A (pt)
AR (1) AR069759A1 (pt)
AT (1) ATE551327T1 (pt)
AU (1) AU2008333261A1 (pt)
BR (1) BRPI0819056A2 (pt)
CA (1) CA2706340C (pt)
CL (1) CL2008003553A1 (pt)
EA (1) EA016832B1 (pt)
MX (1) MX2010006253A (pt)
NZ (1) NZ586521A (pt)
WO (1) WO2009071584A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108403692B (zh) * 2018-03-26 2019-08-16 中国人民解放军军事科学院军事医学研究院 盐酸阿替美唑作为非特异性p450酶抑制剂的应用
CN112225700B (zh) * 2020-11-12 2023-11-17 湖南新合新生物医药有限公司 一种阿替美唑的制备方法
LU103072B1 (en) 2023-02-15 2024-08-19 Univ Ljubljani N,N-DIALKYL-4-(2-ETHYLINDAN-2-YL)-lH-IMIDAZOLE-l-CARBOXAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES
EP4658639A1 (en) 2023-02-01 2025-12-10 Univerza V Ljubljani N,n-dialkyl-4-(2-ethylindan-2-yl)-1h-imidazole-1-carboxamides and related compounds for treatment of neurodegenerative diseases
CN117186010A (zh) * 2023-08-15 2023-12-08 厦门欧瑞捷生物科技有限公司 一种盐酸阿替美唑的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1170188A (en) * 1967-09-15 1969-11-12 Bayer Ag N-trityl-imidazoles and salts and uses thereof
US3872095A (en) * 1967-09-15 1975-03-18 Bayer Ag N-trityl-imidazoles and their production
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
FI81092C (fi) * 1986-05-15 1990-09-10 Farmos Oy Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.
GB9425211D0 (en) * 1994-12-14 1995-02-15 Ucb Sa Substituted 1H-imidazoles
FI116292B (fi) * 2003-01-08 2005-10-31 Juvantia Pharma Ltd Oy Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita
HRP20050895B1 (hr) * 2003-03-12 2014-06-06 Kudos Pharmaceuticals Limited Ftalazinon derivati
FI20050657A0 (fi) * 2005-06-17 2005-06-17 Orion Corp Atipametsolin kiteytysmenetelmä

Also Published As

Publication number Publication date
ATE551327T1 (de) 2012-04-15
US20110028733A1 (en) 2011-02-03
AR069759A1 (es) 2010-02-17
US8431717B2 (en) 2013-04-30
KR20100086029A (ko) 2010-07-29
MX2010006253A (es) 2010-08-18
CA2706340A1 (en) 2009-06-11
WO2009071584A1 (en) 2009-06-11
CN101889003A (zh) 2010-11-17
JP2011506284A (ja) 2011-03-03
EP2225209B1 (en) 2012-03-28
EA016832B1 (ru) 2012-07-30
CA2706340C (en) 2016-04-05
EP2225209A1 (en) 2010-09-08
NZ586521A (en) 2012-02-24
CL2008003553A1 (es) 2009-11-27
AU2008333261A1 (en) 2009-06-11
EA201000740A1 (ru) 2010-12-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.