BRPI0817567A2 - Filamento à base de ácido hialurônico sob forma ácida livre e seu método de obtenção - Google Patents

Filamento à base de ácido hialurônico sob forma ácida livre e seu método de obtenção

Info

Publication number: BRPI0817567A2
Authority: BR; Brazil
Prior art keywords: obtaining; based filament; hyaluronic acid; free acid; acid form
Prior art date: 2007-09-28

Application number

Other languages

English (en)

Inventor

Alain Domard

Laurent David

Florence Dupasquier

Original Assignee

Univ Claude Bernard Lyon

Centre Nat Rech Scient

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-28

Filing date

2008-09-26

Publication date

2015-04-07

2008-09-26 Application filed by Univ Claude Bernard Lyon, Centre Nat Rech Scient filed Critical Univ Claude Bernard Lyon

2015-04-07 Publication of BRPI0817567A2 publication Critical patent/BRPI0817567A2/pt

2018-07-24 Publication of BRPI0817567B1 publication Critical patent/BRPI0817567B1/pt

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
229920002674 hyaluronan Polymers 0.000 title 1
229960003160 hyaluronic acid Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/06—Coating with compositions not containing macromolecular substances
- C08J7/065—Low-molecular-weight organic substances, e.g. absorption of additives in the surface of the article
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/06—Wet spinning methods
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F11/00—Chemical after-treatment of artificial filaments or the like during manufacture
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
- D06M13/10—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing oxygen
- D06M13/184—Carboxylic acids; Anhydrides, halides or salts thereof
- D06M13/1845—Aromatic mono- or polycarboxylic acids
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
- D06M15/03—Polysaccharides or derivatives thereof
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
- D06M15/15—Proteins or derivatives thereof
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/19—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with synthetic macromolecular compounds
- D06M15/21—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
- D06M15/227—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds of hydrocarbons, or reaction products thereof, e.g. afterhalogenated or sulfochlorinated
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
- C08J2305/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M16/00—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M2101/00—Chemical constitution of the fibres, threads, yarns, fabrics or fibrous goods made from such materials, to be treated
- D06M2101/02—Natural fibres, other than mineral fibres
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2913—Rod, strand, filament or fiber
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2913—Rod, strand, filament or fiber
- Y10T428/2933—Coated or with bond, impregnation or core
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2913—Rod, strand, filament or fiber
- Y10T428/298—Physical dimension

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Textile Engineering (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Mechanical Engineering (AREA)
Polymers & Plastics (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Bioinformatics & Cheminformatics (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Materials For Medical Uses (AREA)
Artificial Filaments (AREA)

BRPI0817567-5A 2007-09-28 2008-09-26 Filamento à base de ácido hialurônico sob forma ácida livre, seu processo de preparação por fiação via úmida e utilização do mesmo BRPI0817567B1 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0757957A FR2921675B1 (fr)	2007-09-28	2007-09-28	Filament a base d'acide hyaluronique et son procede d'obtention.
FR0757957		2007-09-28
PCT/FR2008/051729 WO2009050389A2 (fr)	2007-09-28	2008-09-26	Filament a base d'acide hyaluronique sous forme acide libre et son procede d'obtention

Publications (2)

Publication Number	Publication Date
BRPI0817567A2 true BRPI0817567A2 (pt)	2015-04-07
BRPI0817567B1 BRPI0817567B1 (pt)	2018-07-24

Family

ID=39444490

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0817567-5A BRPI0817567B1 (pt)	2007-09-28	2008-09-26	Filamento à base de ácido hialurônico sob forma ácida livre, seu processo de preparação por fiação via úmida e utilização do mesmo

Country Status (5)

Country	Link
US (2)	US8753671B2 (pt)
EP (1)	EP2193228A2 (pt)
BR (1)	BRPI0817567B1 (pt)
FR (1)	FR2921675B1 (pt)
WO (1)	WO2009050389A2 (pt)

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ES2658609T3 (es)	2008-09-02	2018-03-12	Tautona Group Lp	Hilos de ácido hialurónico y/o derivados de los mismos, métodos para fabricar los mismos, y usos de los mismos
CZ302504B6 (cs)	2009-12-11	2011-06-22	Contipro C A.S.	Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace
CZ2009835A3 (cs)	2009-12-11	2011-06-22	Contipro C A.S.	Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
ES2376680B8 (es) *	2010-08-16	2013-04-30	Nylstar, S.A.	Fibra textil cosmética, procedimiento de obtención y su empleo.
CZ20101001A3 (cs) *	2010-12-31	2012-02-08	Cpn S.R.O.	Hyaluronová vlákna, zpusob jejich prípravy a použití
CN102813961A (zh) *	2011-06-10	2012-12-12	冯淑芹	一种含有亚微米级透明质酸微球的注射凝胶与制备方法
CZ303879B6 (cs)	2012-02-28	2013-06-05	Contipro Biotech S.R.O.	Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
CZ2012282A3 (cs)	2012-04-25	2013-11-06	Contipro Biotech S.R.O.	Zesítovaný derivát hyaluronanu, zpusob jeho prípravy, hydrogel a mikrovlákna na jeho bázi
CZ304651B6 (cs)	2012-05-11	2014-08-20	Contipro Biotech S.R.O.	Způsob přípravy mikrovláken, způsob výroby krytů ran, kryty ran a zařízení pro přípravu polysacharidových vláken
CZ304512B6 (cs)	2012-08-08	2014-06-11	Contipro Biotech S.R.O.	Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
CZ2012843A3 (cs)	2012-11-27	2014-02-05	Contipro Biotech S.R.O.	Nekonečná vlákna na bázi hyaluronanu, selektivně oxidovaného v poloze 6 N-acetyl-D-glukosaminové části, jejich příprava, použití, nitě, střiže, příze, textilie a způsob jejich úpravy
CZ304654B6 (cs)	2012-11-27	2014-08-20	Contipro Biotech S.R.O.	Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
CZ2012841A3 (cs)	2012-11-27	2014-02-19	Contipro Biotech S.R.O.	Vlákna založená na hydrofobizovaném hyaluronanu, způsob jejich přípravy a použití, textilie na jejich bázi a použití
CZ305153B6 (cs)	2014-03-11	2015-05-20	Contipro Biotech S.R.O.	Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
CZ2014451A3 (cs)	2014-06-30	2016-01-13	Contipro Pharma A.S.	Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
CZ309295B6 (cs)	2015-03-09	2022-08-10	Contipro A.S.	Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
CN104771780B (zh) *	2015-04-09	2017-04-12	中国工程物理研究院核物理与化学研究所	一种用于敷料的高分子水凝胶的制备方法
CZ2015398A3 (cs)	2015-06-15	2017-02-08	Contipro A.S.	Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs)	2015-06-26	2017-04-26	Contipro A.S.	Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
KR101709608B1 (ko) *	2015-09-03	2017-03-09	(주)진우바이오	용융 방사에 의한 히알루론산염 파이버의 제조방법 및 이로부터 제조된 히알루론산염 파이버
CZ306354B6 (cs)	2015-10-09	2016-12-14	Contipro A.S.	Nekonečná vlákna typu jádro-obal zahrnující kombinaci nativního a C11-C18 acylovaného hyaluronanu nebo C11-C18 acylovaných hyaluronanů, způsob jejich přípravy a použití, střiž, příze a textilie z těchto vláken a jejich použití
CZ308106B6 (cs)	2016-06-27	2020-01-08	Contipro A.S.	Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití
CN108144119B (zh) *	2018-01-12	2021-02-23	郑州大学	一种在生物镁合金表面磷灰石涂层上制备抗菌透明质酸钠及壳聚糖双分子层的方法
CN108660741B (zh) *	2018-04-26	2020-08-11	海斯摩尔生物科技有限公司	一种抗菌壳聚糖纤维的制备方法
KR102245629B1 (ko) *	2019-04-10	2021-04-30	주식회사 제네웰	히알루론산계 녹는 필름, 이의 제조방법 및 이에 사용되는 이형지
BR112023004156A2 (pt)	2020-09-22	2023-04-04	Swimc Llc	Composição de revestimento, artigo revestido, e, método para produzir uma composição de revestimento
JP7346551B2 (ja) *	2020-11-26	2023-09-19	ジンウバイオカンパニーリミテッド	ヒアルロン酸塩ファイバーおよびその製造方法
KR102834415B1 (ko)	2022-07-22	2025-07-17	주식회사 블리스팩	나노섬유와 고분자량 수용성 중합체로 이루어진 매트릭스를 포함하는 모노 필라멘트 및 그 제조방법

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2007
- 2007-09-28 FR FR0757957A patent/FR2921675B1/fr not_active Expired - Fee Related
2008
- 2008-09-26 WO PCT/FR2008/051729 patent/WO2009050389A2/fr not_active Ceased
- 2008-09-26 BR BRPI0817567-5A patent/BRPI0817567B1/pt not_active IP Right Cessation
- 2008-09-26 EP EP08839182A patent/EP2193228A2/fr not_active Withdrawn
- 2008-09-26 US US12/680,257 patent/US8753671B2/en not_active Expired - Fee Related
2014
- 2014-05-05 US US14/269,315 patent/US9044410B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US8753671B2 (en)	2014-06-17
WO2009050389A3 (fr)	2009-11-26
BRPI0817567B1 (pt)	2018-07-24
US20100310631A1 (en)	2010-12-09
FR2921675B1 (fr)	2010-03-19
EP2193228A2 (fr)	2010-06-09
FR2921675A1 (fr)	2009-04-03
US20140242146A1 (en)	2014-08-28
US9044410B2 (en)	2015-06-02
WO2009050389A2 (fr)	2009-04-23

Publication	Publication Date	Title
BRPI0817567A2 (pt)	2015-04-07	Filamento à base de ácido hialurônico sob forma ácida livre e seu método de obtenção
BRPI0923760A2 (pt)	2016-01-26	artigos nanoestruturados e métodos para fabricação de artigos nanoestruturados
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