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BRPI0817052A2 - Métodos para o tratamento de uma doença auto-imune e distúrbio, método de inibição de atividade biológica, método para aumentar uma atividade biológica, método para a detecção de uma doença auto-imune, população de células t cd4+, método para isolar uma população de células t cd4+, kit, uso de um modulador crtam, modulador crtam e anticorpo. - Google Patents

Métodos para o tratamento de uma doença auto-imune e distúrbio, método de inibição de atividade biológica, método para aumentar uma atividade biológica, método para a detecção de uma doença auto-imune, população de células t cd4+, método para isolar uma população de células t cd4+, kit, uso de um modulador crtam, modulador crtam e anticorpo.

Info

Publication number
BRPI0817052A2
BRPI0817052A2 BRPI0817052A BRPI0817052A2 BR PI0817052 A2 BRPI0817052 A2 BR PI0817052A2 BR PI0817052 A BRPI0817052 A BR PI0817052A BR PI0817052 A2 BRPI0817052 A2 BR PI0817052A2
Authority
BR
Brazil
Prior art keywords
crtam
modulator
biological activity
autoimmune disease
population
Prior art date
Application number
Other languages
English (en)
Inventor
Andrew Chan
Jung-Hua Yeh
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BRPI0817052A2 publication Critical patent/BRPI0817052A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P17/00—Drugs for dermatological disorders
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C12N2799/00—Uses of viruses
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    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

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BRPI0817052 2007-08-30 2008-08-29 Métodos para o tratamento de uma doença auto-imune e distúrbio, método de inibição de atividade biológica, método para aumentar uma atividade biológica, método para a detecção de uma doença auto-imune, população de células t cd4+, método para isolar uma população de células t cd4+, kit, uso de um modulador crtam, modulador crtam e anticorpo. BRPI0817052A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96905907P 2007-08-30 2007-08-30
US3402108P 2008-03-05 2008-03-05
PCT/US2008/074908 WO2009029883A2 (en) 2007-08-30 2008-08-29 Methods and compositions for modulating t cells

Publications (1)

Publication Number Publication Date
BRPI0817052A2 true BRPI0817052A2 (pt) 2015-03-24

Family

ID=39929595

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0817052 BRPI0817052A2 (pt) 2007-08-30 2008-08-29 Métodos para o tratamento de uma doença auto-imune e distúrbio, método de inibição de atividade biológica, método para aumentar uma atividade biológica, método para a detecção de uma doença auto-imune, população de células t cd4+, método para isolar uma população de células t cd4+, kit, uso de um modulador crtam, modulador crtam e anticorpo.

Country Status (10)

Country Link
US (1) US20100247430A1 (pt)
EP (1) EP2190468A2 (pt)
JP (1) JP2010538018A (pt)
KR (1) KR20100067089A (pt)
CN (1) CN101854949A (pt)
AU (1) AU2008292854A1 (pt)
BR (1) BRPI0817052A2 (pt)
CA (1) CA2715305A1 (pt)
MX (1) MX2010002028A (pt)
WO (1) WO2009029883A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2625259T3 (es) 2006-08-29 2017-07-19 Oxford Biotherapeutics Ltd Identificación de proteína asociada con carcinoma hepatocelular, glioblastoma y cáncer de pulmón
EA028336B1 (ru) 2009-03-05 2017-11-30 МЕДАРЕКС Л.Л.Си. Полностью человеческие антитела, специфические в отношении cadm1
KR101317507B1 (ko) * 2010-08-30 2013-10-15 가톨릭대학교 산학협력단 레바미피드를 유효성분으로 포함하는 암 또는 면역질환의 예방 또는 치료용 조성물
LT3351936T (lt) * 2011-06-29 2025-02-25 QIAGEN Australia Holding Pty. Ltd. Padidinto jautrumo ląstelinio imuninio atsako tyrimas
US10260089B2 (en) 2012-10-29 2019-04-16 The Research Foundation Of The State University Of New York Compositions and methods for recognition of RNA using triple helical peptide nucleic acids
KR102654784B1 (ko) * 2014-07-18 2024-04-04 사이아스 가부시키가이샤 다능성 줄기세포로부터 세포-기반 면역요법용 t 세포를 유도하는 방법
JP2018500006A (ja) 2014-10-31 2018-01-11 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 改変ｔ細胞における遺伝子発現の改変およびその使用
US20170022286A1 (en) * 2015-03-23 2017-01-26 The Board Of Trustees Of The Leland Stanford Junior University Medical uses of crtam agonists
JP6536944B2 (ja) * 2015-06-05 2019-07-03 株式会社膠原病研究所 自己免疫疾患の発症に関与する細胞を判定する方法及びその利用
HUE053674T2 (hu) * 2015-12-23 2021-07-28 Medigene Immunotherapies Gmbh Antigén-specifikus TCR receptorok új generációja
WO2019086878A1 (en) * 2017-11-02 2019-05-09 Oxford Biotherapeutics Ltd Antibodies and methods of use
US20230131219A1 (en) * 2019-11-08 2023-04-27 The University Of North Carolina At Chapel Hill Use of agonists to augment car t function in solid tumors
CN116194480A (zh) 2020-08-13 2023-05-30 百时美施贵宝公司 将il-2重定向到目的靶细胞的方法
TW202317631A (zh) * 2021-06-30 2023-05-01 大陸商南京聖和藥業股份有限公司 抗crtam抗體及其應用
CN115807070A (zh) * 2021-09-15 2023-03-17 首都医科大学附属北京胸科医院 一种结核分枝杆菌记忆样nk细胞筛查的标志物及其应用
CN114966057B (zh) * 2022-06-13 2025-10-28 上海市肺科医院 一种结核病的免疫标志物及其应用
AU2023308064A1 (en) 2022-07-11 2025-02-27 Genuv Inc. Cytokine fusion protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1648935A2 (en) * 2003-07-25 2006-04-26 Amgen Inc. Antagonists and agonists of ldcam and methods of use

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Publication number Publication date
CA2715305A1 (en) 2009-03-05
WO2009029883A3 (en) 2009-11-05
MX2010002028A (es) 2010-03-15
JP2010538018A (ja) 2010-12-09
KR20100067089A (ko) 2010-06-18
WO2009029883A2 (en) 2009-03-05
AU2008292854A1 (en) 2009-03-05
EP2190468A2 (en) 2010-06-02
CN101854949A (zh) 2010-10-06
US20100247430A1 (en) 2010-09-30

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