BRPI0816784A2 - Fatores neuro-endócrinos para o tratamento de doenças degenerativas - Google Patents

Fatores neuro-endócrinos para o tratamento de doenças degenerativas

Info

Publication number: BRPI0816784A2
Authority: BR; Brazil
Prior art keywords: treatment; degenerative diseases; neuroendocrine factors; neuroendocrine; factors
Prior art date: 2007-09-14

Application number

Other languages

English (en)

Inventor

Anja Bosserhoff

Thomas Schubert

Elisabeth Hustert

Original Assignee

Scil Technology Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-14

Filing date

2008-09-12

Publication date

2015-03-24

2007-09-14 Priority claimed from EP07018131A external-priority patent/EP2036921A1/en

2008-09-12 Application filed by Scil Technology Gmbh filed Critical Scil Technology Gmbh

2015-03-24 Publication of BRPI0816784A2 publication Critical patent/BRPI0816784A2/pt

2016-01-19 Publication of BRPI0816784A8 publication Critical patent/BRPI0816784A8/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Toxicology (AREA)
Physical Education & Sports Medicine (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Dispersion Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

BRPI0816784A 2007-09-14 2008-09-12 Fatores neuro-endócrinos para o tratamento de doenças degenerativas BRPI0816784A8 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP07018131A EP2036921A1 (en)	2007-09-14	2007-09-14	Use of Slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases
EP08006810		2008-04-03
PCT/EP2008/007579 WO2009033715A2 (en)	2007-09-14	2008-09-12	Neuroendocrine factors for treatment of degenerative diseases

Publications (2)

Publication Number	Publication Date
BRPI0816784A2 true BRPI0816784A2 (pt)	2015-03-24
BRPI0816784A8 BRPI0816784A8 (pt)	2016-01-19

Family

ID=40452588

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0816784A BRPI0816784A8 (pt)	2007-09-14	2008-09-12	Fatores neuro-endócrinos para o tratamento de doenças degenerativas

Country Status (13)

Country	Link
US (1)	US20110002972A1 (pt)
EP (1)	EP2212344B1 (pt)
JP (1)	JP2010539123A (pt)
KR (1)	KR20100075493A (pt)
CN (1)	CN101821283A (pt)
AU (1)	AU2008297889A1 (pt)
BR (1)	BRPI0816784A8 (pt)
CA (1)	CA2699411A1 (pt)
MX (1)	MX2010002716A (pt)
NZ (1)	NZ583851A (pt)
RU (1)	RU2496790C2 (pt)
WO (1)	WO2009033715A2 (pt)
ZA (1)	ZA201001644B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1400024B1 (it) *	2010-05-21	2013-05-17	Uni Politecnica Delle Marche	Uso farmaceutico di semaforine.
UY33833A (es) *	2010-12-23	2012-07-31	Sanofi Sa	Proteína de fusión Robo1-Fc para su uso en el tratamiento del hepatocarcinoma
ES3013463T3 (en) *	2011-07-04	2025-04-14	Mesoblast Inc	Treating or preventing rheumatic disease
KR101617497B1 (ko) *	2012-06-15	2016-05-03	재단법인 아산사회복지재단	Slit3의 lrr2 유전자 또는 그 발현 단백질을 유효성분으로 함유하는 골절 또는 골다공증 예방 또는 치료용 약학적 조성물
ES2442242B1 (es) *	2012-08-09	2014-11-25	Biotechnology Institute, I Mas D, S.L.	Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación.
CN104119446A (zh) *	2013-04-26	2014-10-29	李华顺	含有富含亮氨酸重复序列的融合蛋白及其制法和应用
CN104119447A (zh) *	2013-04-26	2014-10-29	李华顺	含有富含亮氨酸重复序列的融合蛋白及其制法和应用
CN104119448A (zh) *	2013-04-26	2014-10-29	李华顺	含有富含亮氨酸重复序列的融合蛋白及其制法和应用
CN104119445A (zh) *	2013-04-26	2014-10-29	李华顺	含有富含亮氨酸重复序列的融合蛋白及其制法和应用
WO2015072527A1 (ja) *	2013-11-13	2015-05-21	国立大学法人大阪大学	ネトリン１含有破骨細胞形成抑制剤
WO2015138874A1 (en)	2014-03-14	2015-09-17	The Research Foundation For The State University Of New York	Neurogenic regulation of bone growth and bone degradation
US11052175B2 (en)	2015-08-19	2021-07-06	Musculoskeletal Transplant Foundation	Cartilage-derived implants and methods of making and using same
US20200397860A1 (en) *	2018-02-14	2020-12-24	Cornell University	Slit and bone growth modulation
JP7340027B2 (ja) *	2019-02-27	2023-09-06	デウンファーマシューティカルカンパニーリミテッド	アルブミンと結合したＳｌｉｔ３タンパク質のＬＲＲＤ２を含む骨関連疾患の予防または治療用組成物
JP2022547305A (ja) *	2019-09-13	2022-11-11	ラトガース，ザステートユニバーシティオブニュージャージー	Ａａｖ適合性ラミニン－リンカー重合タンパク質
CN110772632B (zh) *	2019-11-19	2023-08-11	四川大学华西医院	神经导向因子semaphorin 3a在制备治疗骨关节炎药物中的用途
CN110841057B (zh) *	2019-11-19	2023-08-01	四川大学华西医院	一种神经导向因子Sema在制备治疗骨关节炎巴布膏剂中的应用
CN110684805B (zh) *	2019-11-19	2023-08-01	四川大学华西医院	神经导向因子Sema基因重组慢病毒载体在制备治疗骨关节炎药物中的应用
CN110694051B (zh) *	2019-11-19	2023-08-01	四川大学华西医院	一种神经导向因子Sema在制备治疗骨关节炎注射剂中的应用
CN110721308B (zh) *	2019-11-19	2023-08-01	四川大学华西医院	一种用于治疗骨关节炎的药物复方制剂及其制备方法
CN110711244B (zh) *	2019-11-19	2023-08-01	四川大学华西医院	一种神经导向因子Sema在制备治疗骨关节炎搽剂中的应用
US20240277861A1 (en) *	2021-07-26	2024-08-22	Purotech Bio, Inc.	Anti-hepatitis b virus agent targeting host factor lipg

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2700117B1 (fr) *	1993-01-07	1995-02-03	Rhone Poulenc Rorer Sa	Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens.
JPH1116490A (ja) *	1997-06-26	1999-01-22	Kyocera Corp	プラズマディスプレイパネル用隔壁の製造方法及びプラズマディスプレイパネル用基板
US20030032057A1 (en) *	1997-08-26	2003-02-13	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6342370B1 (en) *	1997-10-31	2002-01-29	Osiris Therapeutics, Inc.	Human slit polypeptide and polynucleotides encoding same
JPH11164690A (ja) *	1997-12-05	1999-06-22	Asahi Chem Ind Co Ltd	脊椎動物スリット蛋白質
US20030096955A1 (en) *	1998-09-01	2003-05-22	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1163336A2 (en) *	1999-03-17	2001-12-19	Washington University	Vertebrate protein slit, dna sequence encoding it and uses thereof
AU2001278655A1 (en) *	2000-07-18	2002-01-30	Compugen Ltd.	Novel nucleic acid and amino acid sequences
CA2416732C (en) *	2000-08-02	2016-02-09	Brad St. Croix	Endothelial cell expression patterns
WO2002012346A2 (en) *	2000-08-10	2002-02-14	Pharmacia Corporation	A new slit-like protein obtained from a cdna library from hs-5 stromal cell line
US20040265808A1 (en) *	2001-04-05	2004-12-30	Teresa Garcia	Genes involved in osteogenesis, and methods of use
US20050014680A1 (en) *	2003-04-15	2005-01-20	Crabtree Gerald R.	Methods and compositions for enhancing neuron growth and survival
US20060025335A1 (en) *	2004-01-30	2006-02-02	Kinane Thomas B	Netrin compositions and methods of using the same
BRPI0720038A2 (pt) *	2006-12-11	2013-12-24	Univ Utah Res Found	Métodos para inibir a permeabilidade vascular em tecido, para triar ou avaliar um agente que inibe a permeabilidade vascular, para tratar ou prevenir a síndrome da angústia respiratória, a retinopatia de prematuridade, a retinopatia diabética e a degeneração macular úmida em um indivíduo, para tratar indivíduos com sugestões repulsivas ou miméticos e para promover a angiogênese em um tecido, polipeptídeo isolado, ácido nucleico isolado, e, vetor

2008
- 2008-09-12 CA CA2699411A patent/CA2699411A1/en not_active Abandoned
- 2008-09-12 RU RU2010114713/10A patent/RU2496790C2/ru not_active IP Right Cessation
- 2008-09-12 CN CN200880111279A patent/CN101821283A/zh active Pending
- 2008-09-12 KR KR1020107007806A patent/KR20100075493A/ko not_active Withdrawn
- 2008-09-12 US US12/677,830 patent/US20110002972A1/en not_active Abandoned
- 2008-09-12 BR BRPI0816784A patent/BRPI0816784A8/pt not_active IP Right Cessation
- 2008-09-12 MX MX2010002716A patent/MX2010002716A/es not_active Application Discontinuation
- 2008-09-12 NZ NZ583851A patent/NZ583851A/en not_active IP Right Cessation
- 2008-09-12 AU AU2008297889A patent/AU2008297889A1/en not_active Abandoned
- 2008-09-12 WO PCT/EP2008/007579 patent/WO2009033715A2/en not_active Ceased
- 2008-09-12 JP JP2010524408A patent/JP2010539123A/ja active Pending
- 2008-09-12 EP EP08802131.6A patent/EP2212344B1/en active Active
2010
- 2010-03-08 ZA ZA2010/01644A patent/ZA201001644B/en unknown

Also Published As

Publication number	Publication date
JP2010539123A (ja)	2010-12-16
US20110002972A1 (en)	2011-01-06
EP2212344A2 (en)	2010-08-04
BRPI0816784A8 (pt)	2016-01-19
NZ583851A (en)	2012-06-29
CN101821283A (zh)	2010-09-01
WO2009033715A2 (en)	2009-03-19
RU2496790C2 (ru)	2013-10-27
CA2699411A1 (en)	2009-03-19
MX2010002716A (es)	2010-07-05
KR20100075493A (ko)	2010-07-02
RU2010114713A (ru)	2011-10-20
EP2212344B1 (en)	2014-03-26
AU2008297889A1 (en)	2009-03-19
ZA201001644B (en)	2011-03-30
WO2009033715A3 (en)	2010-03-18

Publication	Publication Date	Title
BRPI0816784A2 (pt)	2015-03-24	Fatores neuro-endócrinos para o tratamento de doenças degenerativas
BRPI1015569A2 (pt)	2016-08-16	compostos úteis para o tratamento de doenças degenerativas e inflamatórias.
BRPI0716844A2 (pt)	2013-10-22	Inidores de quinase úteis para o tratamento de doenças proliferativas
BRPI0916862A2 (pt)	2016-02-10	compostos úteis para o tratamento de doenças degenerativas e inflamatórias
CR11019A (es)	2009-10-20	3-imidazolil-indoles para el tratamiento de enfermedades proliferativas
BRPI0817096A2 (pt)	2017-05-02	análogos de tiazolidinodiona para o tratamento de hipertensão
HUS1600048I1 (hu)	2017-01-30	Készítmény Fabry-kór kezelésére
HUE054495T2 (hu)	2021-09-28	Rák kezelésére szolgáló készítmény
BRPI0908026A2 (pt)	2015-07-21	Métodos para o tratamento de doenças do intestino
BRPI0921321A2 (pt)	2018-10-16	métodos para o tratamento de indwcções e tumores
PL3354276T3 (pl)	2020-09-21	Kompozycje do leczenia zapalenia przewodu pokarmowego
BRPI1014759A2 (pt)	2016-04-19	composto útil para o tratamento de doenças degenerativas e inflamatórias
BRPI0813725A2 (pt)	2014-12-30	Métodos e composições para tratamento de doenças
DK2504005T3 (da)	2014-01-13	Anvendelse af 1,3-diphenylprop-2-en-1-on-derivater til behandling af lever-sygdomme
DK2154971T3 (da)	2012-04-02	Synergistisk farmaceutisk kombination til behandling af cancer
BRPI0911577A2 (pt)	2016-01-05	derivados espiro-indol para o tratamento de doenças parasíticas.
DK2056842T3 (da)	2013-01-14	Modificeret galactosylceramid til behandling af cancerøse sygdomme
BRPI0813670A2 (pt)	2014-12-30	Compostos para tratamento
BRPI0812040A2 (pt)	2014-10-21	Indicações para terapia de anti-il-i-beta
BR112012004836A2 (pt)	2019-09-24	pirazinilpiridinas úteis para o tratamento de doenças proliferativas
BRPI1007995A2 (pt)	2019-09-24	orto-aminoamidas para o tratamento de cãncer.
BRPI1009783A2 (pt)	2016-03-08	compostos para o tratamento de distúrbios metabólicos.
BRPI0818170A2 (pt)	2017-05-16	5-cianotienopiridinas para o tratamento de tumores.
BRPI1009448A2 (pt)	2016-03-01	combinações farmacêuticas compreendendo edea119/bay 869766 para o tratamento de cânceres específicos
DK2117565T3 (da)	2012-11-19	Anvendelse af chitosaner til behandlingen af negleinflammatoriske sygdomme

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2016-01-19	B25A	Requested transfer of rights approved	Owner name: FORMYCON GMBH (DE)
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.