BRPI0816426A2 - Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico. - Google Patents
Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico.Info
- Publication number
- BRPI0816426A2 BRPI0816426A2 BRPI0816426-6A2A BRPI0816426A BRPI0816426A2 BR PI0816426 A2 BRPI0816426 A2 BR PI0816426A2 BR PI0816426 A BRPI0816426 A BR PI0816426A BR PI0816426 A2 BRPI0816426 A2 BR PI0816426A2
- Authority
- BR
- Brazil
- Prior art keywords
- investigating
- molecula
- molecule
- nucleic acid
- molecules
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
- 239000000758 substrate Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/701—Integrated with dissimilar structures on a common substrate
- Y10S977/702—Integrated with dissimilar structures on a common substrate having biological material component
- Y10S977/704—Nucleic acids, e.g. DNA or RNA
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/724—Devices having flexible or movable element
- Y10S977/733—Nanodiaphragm
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/778—Nanostructure within specified host or matrix material, e.g. nanocomposite films
- Y10S977/781—Possessing nonosized surface openings that extend partially into or completely through the host material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0717150.7A GB0717150D0 (en) | 2007-09-04 | 2007-09-04 | Apparatus and method |
| PCT/GB2008/050783 WO2009030953A1 (en) | 2007-09-04 | 2008-09-04 | Apparatus and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0816426A2 true BRPI0816426A2 (pt) | 2015-03-03 |
Family
ID=38640188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0816426-6A2A BRPI0816426A2 (pt) | 2007-09-04 | 2008-09-04 | Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico. |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8865455B2 (pt) |
| EP (1) | EP2188618B1 (pt) |
| JP (2) | JP2010538290A (pt) |
| CN (2) | CN103087904A (pt) |
| BR (1) | BRPI0816426A2 (pt) |
| CA (1) | CA2698876A1 (pt) |
| ES (1) | ES2617089T3 (pt) |
| GB (1) | GB0717150D0 (pt) |
| WO (1) | WO2009030953A1 (pt) |
Families Citing this family (49)
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| US9121843B2 (en) | 2007-05-08 | 2015-09-01 | Trustees Of Boston University | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof |
| GB0717150D0 (en) * | 2007-09-04 | 2007-10-17 | Univ Warwick | Apparatus and method |
| EP2196796A1 (en) * | 2008-12-09 | 2010-06-16 | Imec | Single molecule optical spectroscopy in solid-state nanopores in a transmission-based approach |
| EP2483680A4 (en) | 2009-09-30 | 2014-01-01 | Quantapore Inc | ULTRASOUND SEQUENCING OF BIOLOGICAL POLYMERS WITH THE HELP OF A MARKED NANOPORE |
| US8748091B2 (en) * | 2009-12-18 | 2014-06-10 | The Board Of Trustees Of The University Of Illinois | Characterizing stretched polynucleotides in a synthetic nanopassage |
| KR101802541B1 (ko) * | 2010-02-23 | 2017-11-30 | 크리스토퍼 고든 앳우드 | 생물학적 관련 분자 및 이들의 상호작용 특징을 검출하는 방법 |
| US10010272B2 (en) | 2010-05-27 | 2018-07-03 | Profusa, Inc. | Tissue-integrating electronic apparatus |
| EP2402738A3 (en) * | 2010-07-02 | 2012-01-11 | Imec | Spectroscopy using nanopore cavities |
| CN103069267B (zh) * | 2010-09-29 | 2016-05-11 | 株式会社日立高新技术 | 生物聚合物的光学的解析装置以及方法 |
| CA2813041C (en) | 2010-10-06 | 2018-08-21 | Natalie Ann Wisniewski | Tissue-integrating sensors |
| US9274053B2 (en) * | 2011-05-18 | 2016-03-01 | Uvic Industry Partnerships Inc. | Flow through metallic nanohole arrays |
| JPWO2012165400A1 (ja) * | 2011-06-03 | 2015-02-23 | 株式会社日立ハイテクノロジーズ | 生体ポリマーの光学的解析装置及び方法 |
| GB2493397A (en) | 2011-08-05 | 2013-02-06 | Base4 Innovation Ltd | Pulse counter for single photon events |
| US9007576B2 (en) | 2011-08-12 | 2015-04-14 | Savannah River Nuclear Solutions, Llc | Surface enhanced Raman scattering spectroscopic waveguide |
| WO2013039778A2 (en) | 2011-09-12 | 2013-03-21 | The University Of North Carolina At Chapel Hill | Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods |
| WO2013074546A1 (en) * | 2011-11-14 | 2013-05-23 | The Regents Of The University Of California | Two- chamber dual-pore device |
| GB2497784A (en) | 2011-12-20 | 2013-06-26 | Base4 Innovation Ltd | Identification of polymers using nanopore devices |
| JP6339024B2 (ja) * | 2012-02-10 | 2018-06-06 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill | 流体ナノファンネルを有する装置、関連する方法、製造及び解析システム |
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| US10816550B2 (en) | 2012-10-15 | 2020-10-27 | Nanocellect Biomedical, Inc. | Systems, apparatus, and methods for sorting particles |
| US9651539B2 (en) | 2012-10-28 | 2017-05-16 | Quantapore, Inc. | Reducing background fluorescence in MEMS materials by low energy ion beam treatment |
| GB201301178D0 (en) * | 2013-01-23 | 2013-03-06 | Dynamic Biosensors Gmbh | Method for sequencing a template nucleic acid immobilized on a substrate |
| US10261065B2 (en) | 2013-02-28 | 2019-04-16 | The University Of North Carolina At Chapel Hill | Nanofluidic devices with integrated components for the controlled capture, trapping, and transport of macromolecules and related methods of analysis |
| NZ711033A (en) | 2013-03-13 | 2020-03-27 | Univ North Carolina Chapel Hill | Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis |
| US20160003732A1 (en) * | 2013-03-14 | 2016-01-07 | Hewlett-Packard Development Company, L.P. | Devices to detect a substance and methods of producing such a device |
| BR112015022216A2 (pt) | 2013-03-14 | 2017-07-18 | Profusa Inc | método e dispositivo para correção de sinais ópticos |
| GB201306447D0 (en) * | 2013-04-09 | 2013-05-22 | Base4 Innovation Ltd | Plasmonic detector |
| GB201306446D0 (en) * | 2013-04-09 | 2013-05-22 | Base4 Innovation Ltd | Nanopore plasmonic detector |
| DK3004378T3 (en) | 2013-05-24 | 2018-03-26 | Illumina Cambridge Ltd | Pyrophosphorolytic sequencing using nanopores |
| CA2910019A1 (en) | 2013-05-24 | 2014-11-27 | Quantapore, Inc. | Nanopore-based nucleic acid analysis with mixed fret detection |
| JP2014235043A (ja) * | 2013-05-31 | 2014-12-15 | キヤノン株式会社 | 検査器具、検査システム、および検査方法 |
| CN111544011B (zh) | 2013-06-06 | 2023-06-06 | 普罗菲尤萨股份有限公司 | 用于探测来自植入传感器的光信号的设备和方法 |
| WO2015081294A2 (en) * | 2013-11-26 | 2015-06-04 | Stc.Unm | Innovative nanopore sequencing technology |
| US10612084B2 (en) * | 2014-04-08 | 2020-04-07 | International Business Machines Corporation | Reduction of entropic barrier of polyelectrolyte molecules in a nanopore device with agarose gel |
| EP2995934A1 (en) | 2014-09-15 | 2016-03-16 | Base4 Innovation Ltd | Improved nanopore plasmonic analyser |
| EP2995933A1 (en) | 2014-09-15 | 2016-03-16 | Base4 Innovation Ltd | Improved nanopore plasmonic analyser |
| WO2016057829A1 (en) | 2014-10-10 | 2016-04-14 | Quantapore, Inc. | Nanopore-based polymer analysis with mutually-quenching fluorescent labels |
| WO2016065339A1 (en) | 2014-10-24 | 2016-04-28 | Quantapore, Inc. | Efficient optical analysis of polymers using arrays of nanostructures |
| JP2018505414A (ja) * | 2015-02-02 | 2018-02-22 | ツー ポア ガイズ インコーポレイテッド | サンプルバックグラウンドからの標的ポリヌクレオチドのナノ細孔検出方法 |
| US10471428B2 (en) | 2015-05-11 | 2019-11-12 | The University Of North Carolina At Chapel Hill | Fluidic devices with nanoscale manifolds for molecular transport, related systems and methods of analysis |
| JP6559187B2 (ja) * | 2016-07-01 | 2019-08-14 | ツィンファ ユニバーシティ | 単一分子検出用のキャリア及び単一分子検出装置 |
| CN107561053B (zh) * | 2016-07-01 | 2020-04-28 | 清华大学 | 一种单分子检测方法 |
| CN109477813A (zh) | 2016-07-05 | 2019-03-15 | 昆塔波尔公司 | 基于光学的纳米孔测序 |
| WO2018119400A1 (en) | 2016-12-22 | 2018-06-28 | Profusa, Inc. | System and single-channel luminescent sensor for and method of determining analyte value |
| CA3064273C (en) | 2017-06-20 | 2023-02-21 | Illumina, Inc. | Nanopore sequencers |
| EP3441143B1 (en) * | 2017-08-08 | 2022-04-13 | Roche Diagnostics GmbH | Laboratory instrument base plate |
| CN114846130A (zh) * | 2019-12-03 | 2022-08-02 | 国立研究开发法人科学技术振兴机构 | 纳米孔结构体及包含纳米孔结构体的碱基序列分析装置 |
| US11982626B2 (en) | 2021-01-29 | 2024-05-14 | Armonica Technologies, Inc. | Enhancement structures for surface-enhanced Raman scattering |
| JP7759631B2 (ja) * | 2021-11-19 | 2025-10-24 | 国立大学法人北海道大学 | 微粒子試料のスペクトルデータの生成方法、微粒子の解析方法、微粒子の判別方法、がん細胞由来のエクソソームの有無の判定方法、微粒子のスペクトル計測用基板、微粒子のスペクトル計測用デバイスおよび微粒子のスペクトル計測用装置 |
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-
2007
- 2007-09-04 GB GBGB0717150.7A patent/GB0717150D0/en not_active Ceased
-
2008
- 2008-09-04 CN CN2012102917016A patent/CN103087904A/zh active Pending
- 2008-09-04 CA CA2698876A patent/CA2698876A1/en not_active Abandoned
- 2008-09-04 CN CN2008801144811A patent/CN101842692B/zh not_active Expired - Fee Related
- 2008-09-04 BR BRPI0816426-6A2A patent/BRPI0816426A2/pt not_active IP Right Cessation
- 2008-09-04 WO PCT/GB2008/050783 patent/WO2009030953A1/en not_active Ceased
- 2008-09-04 EP EP08788753.5A patent/EP2188618B1/en not_active Not-in-force
- 2008-09-04 US US12/676,472 patent/US8865455B2/en not_active Expired - Fee Related
- 2008-09-04 JP JP2010523597A patent/JP2010538290A/ja active Pending
- 2008-09-04 ES ES08788753.5T patent/ES2617089T3/es active Active
-
2012
- 2012-04-30 US US13/459,612 patent/US8440403B2/en not_active Expired - Fee Related
-
2014
- 2014-03-12 JP JP2014048399A patent/JP5827360B2/ja not_active Expired - Fee Related
- 2014-09-19 US US14/490,935 patent/US20150001085A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP5827360B2 (ja) | 2015-12-02 |
| JP2010538290A (ja) | 2010-12-09 |
| US20150001085A1 (en) | 2015-01-01 |
| ES2617089T3 (es) | 2017-06-15 |
| US8865455B2 (en) | 2014-10-21 |
| CA2698876A1 (en) | 2009-03-12 |
| CN101842692A (zh) | 2010-09-22 |
| EP2188618B1 (en) | 2016-10-26 |
| CN103087904A (zh) | 2013-05-08 |
| WO2009030953A1 (en) | 2009-03-12 |
| GB0717150D0 (en) | 2007-10-17 |
| US8440403B2 (en) | 2013-05-14 |
| US20110036994A1 (en) | 2011-02-17 |
| CN101842692B (zh) | 2012-09-12 |
| JP2014145771A (ja) | 2014-08-14 |
| EP2188618A1 (en) | 2010-05-26 |
| US20120237940A1 (en) | 2012-09-20 |
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