BRPI0815821A2 - Composições e métodos que empregam antagonistas nmda para alcançar um efeito poupador de anestésico. - Google Patents
Composições e métodos que empregam antagonistas nmda para alcançar um efeito poupador de anestésico.Info
- Publication number
- BRPI0815821A2 BRPI0815821A2 BRPI0815821-5A2A BRPI0815821A BRPI0815821A2 BR PI0815821 A2 BRPI0815821 A2 BR PI0815821A2 BR PI0815821 A BRPI0815821 A BR PI0815821A BR PI0815821 A2 BRPI0815821 A2 BR PI0815821A2
- Authority
- BR
- Brazil
- Prior art keywords
- anesthetics
- compositions
- achieve
- methods
- saving effect
- Prior art date
Links
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 title 1
- 229940035674 anesthetics Drugs 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 239000003193 general anesthetic agent Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96823607P | 2007-08-27 | 2007-08-27 | |
| PCT/US2008/074317 WO2009029618A1 (en) | 2007-08-27 | 2008-08-26 | Compositions and methods employing nmda antagonists for achieving an anesthetic-sparing effect |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0815821A2 true BRPI0815821A2 (pt) | 2015-02-18 |
Family
ID=39797439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0815821-5A2A BRPI0815821A2 (pt) | 2007-08-27 | 2008-08-26 | Composições e métodos que empregam antagonistas nmda para alcançar um efeito poupador de anestésico. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090061024A1 (pt) |
| EP (1) | EP2195031A1 (pt) |
| JP (1) | JP2010537999A (pt) |
| KR (1) | KR20100049663A (pt) |
| CN (1) | CN101896205A (pt) |
| AR (1) | AR068350A1 (pt) |
| AU (1) | AU2008293622A1 (pt) |
| BR (1) | BRPI0815821A2 (pt) |
| CA (1) | CA2697739A1 (pt) |
| CL (1) | CL2008002523A1 (pt) |
| MX (1) | MX2010002191A (pt) |
| TW (1) | TW200918077A (pt) |
| WO (1) | WO2009029618A1 (pt) |
| ZA (1) | ZA201001252B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010226479A1 (en) | 2009-03-19 | 2011-09-22 | Wyeth Llc | Methods for the preparation of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7) -en-2-yl)ethyl]phosphonic acid and precursors thereof |
| US11083696B2 (en) * | 2011-09-21 | 2021-08-10 | University College Cardiff Consultants Limited | Dispersion anaesthetic device |
| KR20150036535A (ko) | 2012-07-10 | 2015-04-07 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 마취를 유도하는 방법 |
| FR2998892B1 (fr) | 2012-12-04 | 2015-01-02 | Pf Medicament | Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments |
| WO2015149066A1 (en) * | 2014-03-28 | 2015-10-01 | University Of Virginia Patent Foundation | General anesthetics that are not neurotoxic |
| WO2015187918A2 (en) | 2014-06-05 | 2015-12-10 | The Regents Of The University Of California | Halogenated ether compounds and methods of inducing anesthesia |
| FR3022456B1 (fr) * | 2014-06-20 | 2016-07-15 | Air Liquide | Xenon associe a un antagoniste des recepteurs nmda pour lutter contre une proliferation tumorale dans le systeme nerveux central |
| US20200297734A1 (en) | 2015-06-19 | 2020-09-24 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| US10391102B2 (en) * | 2015-06-19 | 2019-08-27 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| US10555952B2 (en) | 2015-06-19 | 2020-02-11 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| CN106176770A (zh) * | 2016-07-11 | 2016-12-07 | 孙剑 | 一种男性发育期注射麻醉剂 |
| CN106109468A (zh) * | 2016-07-11 | 2016-11-16 | 孙剑 | 一种女性发育期注射麻醉剂 |
| CN106166159A (zh) * | 2016-07-11 | 2016-11-30 | 孙剑 | 一种复方注射麻醉剂 |
| CN109794292B (zh) * | 2019-01-10 | 2021-12-07 | 天津大学 | Z-选择性钌卡宾烯烃复分解催化剂及其制备方法与应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168103A (en) * | 1991-01-22 | 1992-12-01 | American Home Products Corporation | [[2-(amino-3,4-dioxo-1-cyclobuten-1-yl) amino]alkyl]-acid derivatives |
| US5124319A (en) * | 1991-10-11 | 1992-06-23 | American Home Products Corporation | Benzimidazole phosphono-amino acids |
| US5990307A (en) * | 1997-08-01 | 1999-11-23 | American Home Products Corporation | Process for the preparation of [2-((8.9)-Dioxo-2,6-Diazabicyclo [5.2.0]-Non-1(7)-en-2yl) Ethyl]Phosphonic acid |
| US6225343B1 (en) * | 1999-06-16 | 2001-05-01 | Nastech Pharmaceutical Company, Inc. | Compositions and methods comprising morphine gluconate |
| US7089200B2 (en) * | 1999-12-21 | 2006-08-08 | Third Millennium Management Pty Ltd | Payroll management method and apparatus |
| UA78529C2 (en) * | 2001-10-10 | 2007-04-10 | Wyeth Corp | Derivatives of [[2-(amino-3,4-dioxo-1-cyclobutene-1-yl)amino]alkyl] acid for treating pain |
| US20040082543A1 (en) * | 2002-10-29 | 2004-04-29 | Pharmacia Corporation | Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain |
| CN1802161A (zh) * | 2003-04-09 | 2006-07-12 | 惠氏公司 | [2-(8,9-二氧代-2,6-二氮杂双环[5.2.0]壬-1(7)-烯-2-基)烷基]-膦酸及其衍生物的鼻内给药药用组合物及用法 |
| ATE481103T1 (de) * | 2003-04-09 | 2010-10-15 | Wyeth Llc | Derivate von 2-(8,9-dioxo-2,6- diazabicyclo(5.2.0)non-1(7)-en-2- yl)alkylphosphonsäure und deren verwendung als n- methyl-d-aspartat- (nmda-) rezeptorantagonisten |
| US20050142192A1 (en) * | 2003-10-15 | 2005-06-30 | Wyeth | Oral administration of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and derivatives |
| EP1797104B1 (en) * | 2004-10-08 | 2009-11-25 | Wyeth | Derivatives of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl]phosphonic acid and method of making them |
-
2008
- 2008-08-26 AU AU2008293622A patent/AU2008293622A1/en not_active Abandoned
- 2008-08-26 JP JP2010523089A patent/JP2010537999A/ja not_active Withdrawn
- 2008-08-26 CN CN2008801134468A patent/CN101896205A/zh active Pending
- 2008-08-26 BR BRPI0815821-5A2A patent/BRPI0815821A2/pt not_active IP Right Cessation
- 2008-08-26 CA CA2697739A patent/CA2697739A1/en not_active Abandoned
- 2008-08-26 MX MX2010002191A patent/MX2010002191A/es not_active Application Discontinuation
- 2008-08-26 WO PCT/US2008/074317 patent/WO2009029618A1/en not_active Ceased
- 2008-08-26 US US12/198,489 patent/US20090061024A1/en not_active Abandoned
- 2008-08-26 EP EP08828330A patent/EP2195031A1/en not_active Withdrawn
- 2008-08-26 KR KR1020107006600A patent/KR20100049663A/ko not_active Ceased
- 2008-08-27 AR ARP080103731A patent/AR068350A1/es not_active Application Discontinuation
- 2008-08-27 CL CL200802523A patent/CL2008002523A1/es unknown
- 2008-08-27 TW TW097132752A patent/TW200918077A/zh unknown
-
2010
- 2010-02-22 ZA ZA2010/01252A patent/ZA201001252B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20090061024A1 (en) | 2009-03-05 |
| CA2697739A1 (en) | 2009-03-05 |
| WO2009029618A1 (en) | 2009-03-05 |
| JP2010537999A (ja) | 2010-12-09 |
| KR20100049663A (ko) | 2010-05-12 |
| CN101896205A (zh) | 2010-11-24 |
| TW200918077A (en) | 2009-05-01 |
| EP2195031A1 (en) | 2010-06-16 |
| MX2010002191A (es) | 2010-03-17 |
| CL2008002523A1 (es) | 2008-10-10 |
| AR068350A1 (es) | 2009-11-11 |
| AU2008293622A1 (en) | 2009-03-05 |
| ZA201001252B (en) | 2011-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |