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BRPI0815613A2 - Composições lipossômicas para administração in vivo de compostos de ácido borônico. - Google Patents

Composições lipossômicas para administração in vivo de compostos de ácido borônico.

Info

Publication number
BRPI0815613A2
BRPI0815613A2 BRPI0815613A BRPI0815613A2 BR PI0815613 A2 BRPI0815613 A2 BR PI0815613A2 BR PI0815613 A BRPI0815613 A BR PI0815613A BR PI0815613 A2 BRPI0815613 A2 BR PI0815613A2
Authority
BR
Brazil
Prior art keywords
boronic acid
acid compounds
vivo administration
liposomal compositions
liposomal
Prior art date
Application number
Other languages
English (en)
Inventor
Zhang Yuanpeng
Anthony Huang
Bing Luo
Jinkang Wang
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0815613A2 publication Critical patent/BRPI0815613A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • A61K9/1278Post-loading, e.g. by ion or pH gradient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0815613 2007-08-21 2008-08-21 Composições lipossômicas para administração in vivo de compostos de ácido borônico. BRPI0815613A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95704507P 2007-08-21 2007-08-21
PCT/US2008/073840 WO2009026427A2 (en) 2007-08-21 2008-08-21 Liposome compositions for in vivo administration of boronic acid compounds

Publications (1)

Publication Number Publication Date
BRPI0815613A2 true BRPI0815613A2 (pt) 2015-03-24

Family

ID=39772942

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815613 BRPI0815613A2 (pt) 2007-08-21 2008-08-21 Composições lipossômicas para administração in vivo de compostos de ácido borônico.

Country Status (13)

Country Link
US (1) US20090092661A1 (pt)
EP (1) EP2190411A2 (pt)
JP (1) JP2010536874A (pt)
KR (1) KR20100095507A (pt)
CN (1) CN101795671A (pt)
AU (1) AU2008288917A1 (pt)
BR (1) BRPI0815613A2 (pt)
CA (1) CA2697042A1 (pt)
CO (1) CO6260056A2 (pt)
EA (1) EA201070296A1 (pt)
EC (1) ECSP109981A (pt)
MX (1) MX2010002100A (pt)
WO (1) WO2009026427A2 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2748921A1 (en) * 2009-01-09 2010-08-12 Sun Pharma Advanced Research Company Limited Bortezumib containing pharmaceutical composition
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
US8263578B2 (en) 2010-03-18 2012-09-11 Innopharma, Inc. Stable bortezomib formulations
WO2011116286A2 (en) * 2010-03-18 2011-09-22 Innopharma, Llc Stable bortezomib formulations
GB201020860D0 (en) * 2010-12-09 2011-01-26 Univ Wolverhampton Disulfiram formulation and uses thereof
WO2013086526A1 (en) * 2011-12-09 2013-06-13 The Regents Of The University Of California Liposomal drug encapsulation
CA2866135A1 (en) * 2012-03-02 2014-09-06 Dr. Reddy's Laboratories Limited Pharmaceutical compositions comprising boronic acid compounds
MX2015000813A (es) * 2012-07-18 2015-09-07 Onyx Therapeutics Inc Composiciones liposómicas de inhibidores de proteasoma basadas en epoxicetona.
KR102310786B1 (ko) * 2013-02-01 2021-10-12 존원 파마, 인코포레이티드 리포좀 내로 난수용성 약물의 원격 부하
CN103142509B (zh) * 2013-03-06 2018-01-02 石药集团中奇制药技术(石家庄)有限公司 一种注射用硼替佐米药物组合物
CA2913023C (en) 2013-05-30 2021-06-08 Nanobiotix Pharmaceutical composition, preparation and uses thereof
EP3102585B1 (en) * 2014-02-03 2021-05-19 Ohio State Innovation Foundation Boronic acid esters and pharmaceutical formulations thereof
CA2962709C (en) 2014-08-04 2023-09-19 Zoneone Pharma, Inc. Remote loading of sparingly water-soluble drugs into lipid vesicles
UA123665C2 (uk) * 2014-11-25 2021-05-12 Кюрадігм Сас Фармацевтична композиція, її одержання і застосування
EP3223796B1 (en) 2014-11-25 2021-07-21 Curadigm Sas Pharmaceutical compositions, preparation and uses thereof
AR102781A1 (es) 2014-11-25 2017-03-22 Nanobiotix Composición farmacéutica que combina al menos dos nanopartículas distintas y un compuesto farmacéutico, su preparación y sus usos
WO2016171446A1 (ko) * 2015-04-20 2016-10-27 동아에스티 주식회사 펩타이드 붕소산 화합물을 함유하는 안정화 약학 제제
EA201792560A1 (ru) 2015-05-28 2018-06-29 Нанобиотикс Наночастицы для применения в качестве терапевтической вакцины
CN106265536B (zh) * 2016-08-24 2019-01-11 江苏豪森药业集团有限公司 硼替佐米药物组合物及其制备方法
CN109045272A (zh) * 2018-08-01 2018-12-21 厦门市壳聚糖生物科技有限公司 一种硼替佐米磷脂复合物及其制备方法与应用
CN112915094A (zh) * 2021-03-26 2021-06-08 东南大学 一种硼替佐米脂质体制剂的制备方法
TW202415382A (zh) * 2022-09-30 2024-04-16 大陸商上海濟煜醫藥科技有限公司 脂質體藥物組合物及其製備方法和用途
WO2024067840A1 (zh) * 2022-09-30 2024-04-04 上海济煜医药科技有限公司 一种脂质体及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0661044A1 (en) * 1991-07-03 1995-07-05 NeXstar Pharmaceuticals, Inc. Drug-containing liposomes
EP0825852B1 (en) * 1995-04-18 2004-07-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Liposome drug-loading method and composition
US7351427B2 (en) * 1998-06-18 2008-04-01 Busulipo Ab Pharmaceutical composition, a method of preparing it and a method of treatment by use thereof
AU2001258106A1 (en) * 2000-05-11 2001-11-20 Celator Technologies Inc. Lipid carrier compositions for improved drug retention
EP1396269A1 (en) * 2002-09-09 2004-03-10 Trigen Limited Boronic acid salts of multivalent metals used in the preparation of a medicament for treating thrombosis
TW200618820A (en) * 2004-11-05 2006-06-16 Alza Corp Liposome formulations of boronic acid compounds

Also Published As

Publication number Publication date
CN101795671A (zh) 2010-08-04
CA2697042A1 (en) 2009-02-26
KR20100095507A (ko) 2010-08-31
EA201070296A1 (ru) 2010-08-30
AU2008288917A1 (en) 2009-02-26
MX2010002100A (es) 2010-03-26
US20090092661A1 (en) 2009-04-09
ECSP109981A (es) 2010-04-30
WO2009026427A2 (en) 2009-02-26
WO2009026427A3 (en) 2009-09-24
JP2010536874A (ja) 2010-12-02
EP2190411A2 (en) 2010-06-02
CO6260056A2 (es) 2011-03-22

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 9/127 (2006.01), A61K 31/69 (2006.01), A61K 4