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BRPI0815110A2 - Sistemas de distribuição para soulubilização de ingredientes farmaceuticamente ativos insolúveis em água - Google Patents

Sistemas de distribuição para soulubilização de ingredientes farmaceuticamente ativos insolúveis em água

Info

Publication number
BRPI0815110A2
BRPI0815110A2 BRPI0815110-5A2A BRPI0815110A BRPI0815110A2 BR PI0815110 A2 BRPI0815110 A2 BR PI0815110A2 BR PI0815110 A BRPI0815110 A BR PI0815110A BR PI0815110 A2 BRPI0815110 A2 BR PI0815110A2
Authority
BR
Brazil
Prior art keywords
soulubilization
insolble
ingredients
distribution systems
pharmaceutically
Prior art date
Application number
BRPI0815110-5A2A
Other languages
English (en)
Inventor
Flavia Giuliana Tinti
Vladimir Matha
Carlo Oliani
Marcia Cristina Breitkreitz
Original Assignee
Ems Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ems Sa filed Critical Ems Sa
Publication of BRPI0815110A2 publication Critical patent/BRPI0815110A2/pt
Publication of BRPI0815110A8 publication Critical patent/BRPI0815110A8/pt
Publication of BRPI0815110B1 publication Critical patent/BRPI0815110B1/pt
Publication of BRPI0815110B8 publication Critical patent/BRPI0815110B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0815110A 2007-08-09 2008-08-11 sistemas de distribuição para solubilização de ingredientes farmaceuticamente ativos insolúveis em água BRPI0815110B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0715493A GB2451811A (en) 2007-08-09 2007-08-09 Delivery composition for solubilising water-insoluble pharmaceutical active ingredients
GB0715493.3 2007-08-09
PCT/IB2008/002552 WO2009019604A2 (en) 2007-08-09 2008-08-11 Delivery systems for solubilising water-insoluble pharmaceutical active ingredients

Publications (4)

Publication Number Publication Date
BRPI0815110A2 true BRPI0815110A2 (pt) 2015-01-27
BRPI0815110A8 BRPI0815110A8 (pt) 2019-01-29
BRPI0815110B1 BRPI0815110B1 (pt) 2021-03-23
BRPI0815110B8 BRPI0815110B8 (pt) 2021-05-25

Family

ID=38543271

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815110A BRPI0815110B8 (pt) 2007-08-09 2008-08-11 sistemas de distribuição para solubilização de ingredientes farmaceuticamente ativos insolúveis em água

Country Status (7)

Country Link
US (1) US9278065B2 (pt)
EP (1) EP2190454B1 (pt)
BR (1) BRPI0815110B8 (pt)
ES (1) ES2663271T3 (pt)
GB (1) GB2451811A (pt)
TR (1) TR201802799T4 (pt)
WO (1) WO2009019604A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2950253B1 (fr) * 2009-09-24 2011-09-23 Ethypharm Sa Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
GB201006038D0 (en) 2010-04-12 2010-05-26 Unilever Plc Improvements relating to antiviral compositions
US20120003162A1 (en) 2010-06-30 2012-01-05 Mcneil-Ppc, Inc. Methods of Preparing Non-Alcohol Bioactive Esential Oil Mouth Rinses
US9084902B2 (en) 2010-06-30 2015-07-21 Mcneil-Ppc, Inc. Non-alchohol bioactive essential oil mouth rinses
ES2969933T3 (es) * 2012-12-31 2024-05-23 Jrx Biotechnology Inc Formulaciones farmacéuticas tópicas líquidas en nanoemulsión
BR112018005315A2 (pt) 2015-09-17 2018-10-09 Jrx Biotechnology Inc abordagens para aprimorar hidratação ou umidificação de pele
WO2021257913A1 (en) * 2020-06-20 2021-12-23 Chavan Neha Compositions for solubilizing water-insoluble active ingredients
CA3248958A1 (en) * 2022-04-15 2023-10-19 Mark Michael MENNING EMULSION FORMULATIONS OF COMPOUNDS THAT ARE SLIGHTLY SOLUBBLE IN WATER

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI65914C (fi) 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
GB8903804D0 (en) 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
US5756450A (en) 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
CA1326995C (en) 1988-01-29 1994-02-15 Kozo Kurihara Cyclosporin compositions
HU201567B (en) 1988-07-21 1990-11-28 Gyogyszerkutato Intezet Process for production of intravenous medical compositions containing cyclosphorin
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
EP1142568A1 (en) 1992-09-25 2001-10-10 Novartis AG Pharmaceutical compositions containing cyclosporins
US20020107183A1 (en) 1993-04-20 2002-08-08 Monika Petszulat Pharmaceutical preparations comprising cyclosporin for oral administration
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
DE4418155A1 (de) 1993-06-01 1994-12-08 Basf Ag Verfahren zur Herstellung von N,N-disubstituierten 3-Aminoacrylsäureestern
WO1996003113A1 (en) 1994-07-22 1996-02-08 G.D. Searle & Co. Self-emulsifying drug delivery system
KR0167613B1 (ko) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 사이클로스포린-함유 연질캅셀제 조성물
KR970064620A (ko) * 1996-03-05 1997-10-13 임성기 사이클로스포린-함유 외용약제 조성물
GB9721367D0 (en) * 1997-10-09 1997-12-10 Univ Liverpool Delivery system
AU4989299A (en) 1998-07-14 2000-02-07 Em Industries, Inc. Microdisperse drug delivery systems
CA2356959C (en) 1998-12-22 2009-03-31 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Water-insoluble drug delivery system
DK1154759T3 (da) * 1998-12-30 2008-12-08 Dexcel Ltd Dispergerbart koncentrat til indgift af cyclosporin
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
US6623765B1 (en) 2000-08-01 2003-09-23 University Of Florida, Research Foundation, Incorporated Microemulsion and micelle systems for solubilizing drugs
GB0029843D0 (en) 2000-12-07 2001-01-24 Univ Belfast Drug delivery system
KR100441167B1 (ko) * 2001-12-27 2004-07-21 씨제이 주식회사 마이크로에멀젼 예비 농축액 조성물
US20040033959A1 (en) * 2002-07-19 2004-02-19 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical compositions for hepatitis C viral protease inhibitors
KR20040015624A (ko) * 2002-08-13 2004-02-19 대한뉴팜(주) 플로르페니콜을 활성성분으로 함유하는 경구투여용약제학적 조성물
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
KR20050108420A (ko) * 2003-04-02 2005-11-16 베링거 인겔하임 인터내셔날 게엠베하 C형 간염 바이러스 프로테아제 억제제를 위한 약제학적조성물
US20060094692A1 (en) * 2004-10-28 2006-05-04 Bionumerik Pharmaceuticals, Inc. Pharmaceutical formulations of camptothecins and process for making same
KR20100028537A (ko) * 2007-04-27 2010-03-12 쉐링-프라우 리미티드 사이클로덱스트린을 사용하여 플로르페니콜 및 구조적으로 관련된 항생제의 용해도를 증진시키기 위한 화합물 및 방법

Also Published As

Publication number Publication date
WO2009019604A3 (en) 2009-07-23
US9278065B2 (en) 2016-03-08
EP2190454A2 (en) 2010-06-02
WO2009019604A2 (en) 2009-02-12
GB2451811A (en) 2009-02-18
BRPI0815110B1 (pt) 2021-03-23
ES2663271T3 (es) 2018-04-11
BRPI0815110B8 (pt) 2021-05-25
TR201802799T4 (tr) 2018-03-21
GB0715493D0 (en) 2007-09-19
US20120177692A1 (en) 2012-07-12
EP2190454B1 (en) 2017-12-20
BRPI0815110A8 (pt) 2019-01-29

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B04C Request for examination: application reinstated [chapter 4.3 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 23/03/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 11/08/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF