[go: up one dir, main page]

BRPI0808574B8 - sistema de controle para pelo menos uma bomba para envio de um fluido em um aparelho de perfusão para pelo menos um órgão - Google Patents

sistema de controle para pelo menos uma bomba para envio de um fluido em um aparelho de perfusão para pelo menos um órgão

Info

Publication number
BRPI0808574B8
BRPI0808574B8 BRPI0808574A BRPI0808574A BRPI0808574B8 BR PI0808574 B8 BRPI0808574 B8 BR PI0808574B8 BR PI0808574 A BRPI0808574 A BR PI0808574A BR PI0808574 A BRPI0808574 A BR PI0808574A BR PI0808574 B8 BRPI0808574 B8 BR PI0808574B8
Authority
BR
Brazil
Prior art keywords
portal vein
hepatic artery
organ
sending
pump
Prior art date
Application number
BRPI0808574A
Other languages
English (en)
Inventor
Brassil John
Original Assignee
Lifeline Scient Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifeline Scient Inc filed Critical Lifeline Scient Inc
Publication of BRPI0808574A2 publication Critical patent/BRPI0808574A2/pt
Publication of BRPI0808574B1 publication Critical patent/BRPI0808574B1/pt
Publication of BRPI0808574B8 publication Critical patent/BRPI0808574B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)

Abstract

regulagem de perfusão. a presente invenção refere-se a um sistema e um método para a regulagem de forma cooperativa das pressões e dos fluxos de vasos de entrada, tais como a veia porta e a artéria hepática para o fígado. esta invenção resolve problemas de fluxo de veia porta abaixo do terapêutico, durante uma preservação de perfusão pela implementação de uma regulagem cooperativa entre as entradas, por exemplo, os sistemas de bombeamento de veia porta e de artéria hepática, em um aparelho de preservação de órgão. ele inclui um algoritmo que se adapta à situação em que a veia porta atingiu um fluxo mínimo e uma pressão máxima. o algoritmo de regulagem cooperativa detecta o problema com a veia porta e o resolve pelo ajuste das condições de fluxo da artéria hepática.
BRPI0808574A 2007-03-01 2008-02-29 sistema de controle para pelo menos uma bomba para envio de um fluido em um aparelho de perfusão para pelo menos um órgão BRPI0808574B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90419007P 2007-03-01 2007-03-01
US60/904,190 2007-03-01
PCT/US2008/002734 WO2008108996A1 (en) 2007-03-01 2008-02-29 Perfusion regulation

Publications (3)

Publication Number Publication Date
BRPI0808574A2 BRPI0808574A2 (pt) 2014-09-09
BRPI0808574B1 BRPI0808574B1 (pt) 2019-11-12
BRPI0808574B8 true BRPI0808574B8 (pt) 2021-06-22

Family

ID=39738585

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0808574A BRPI0808574B8 (pt) 2007-03-01 2008-02-29 sistema de controle para pelo menos uma bomba para envio de um fluido em um aparelho de perfusão para pelo menos um órgão

Country Status (8)

Country Link
US (2) US8986978B2 (pt)
EP (1) EP2131650B1 (pt)
JP (1) JP5704818B2 (pt)
CN (1) CN101677526B (pt)
BR (1) BRPI0808574B8 (pt)
CA (1) CA2679827C (pt)
ES (1) ES2659970T3 (pt)
WO (1) WO2008108996A1 (pt)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
NZ554543A (en) 2004-10-07 2011-03-31 Transmedics Inc Systems for ex-vivo organ care
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US8420380B2 (en) 2008-01-31 2013-04-16 Transmedics, Inc. Systems and methods for ex vivo lung care
US20130323708A1 (en) 2009-07-01 2013-12-05 Massachusetts Institute Of Technology Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
WO2011140241A2 (en) 2010-05-04 2011-11-10 The General Hospital Corporation Methods and compositions for preserving tissues and organs
CN101865878A (zh) * 2010-06-09 2010-10-20 中国科学院南京地理与湖泊研究所 一种智能电泳控温槽及时间温度-凝胶梯度电泳系统
US12096765B1 (en) 2011-03-15 2024-09-24 Paragonix Technologies, Inc. System for hypothermic transport of samples
US9253976B2 (en) 2011-03-15 2016-02-09 Paragonix Technologies, Inc. Methods and devices for preserving tissues
US8828710B2 (en) 2011-03-15 2014-09-09 Paragonix Technologies, Inc. System for hypothermic transport of samples
US8835158B2 (en) 2011-03-15 2014-09-16 Paragonix Technologics, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
US9426979B2 (en) 2011-03-15 2016-08-30 Paragonix Technologies, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
US12279610B2 (en) 2011-03-15 2025-04-22 Paragonix Technonogies, Inc. System for hypothermic transport of samples
US9867368B2 (en) 2011-03-15 2018-01-16 Paragonix Technologies, Inc. System for hypothermic transport of samples
US11178866B2 (en) 2011-03-15 2021-11-23 Paragonix Technologies, Inc. System for hypothermic transport of samples
CN109997836B (zh) 2011-04-14 2022-02-08 特兰斯迈迪茨公司 用于供体肺的离体机器灌注的器官护理溶液
BR112013031607B1 (pt) 2011-06-09 2021-12-21 Lifeline Scientific, Inc. Método de determinação de parâmetros para manter a viabilidade de um fígado ou um rim e método de transporte e/ou armazenamento de pelo menos um fígado
JP2013075888A (ja) * 2011-09-15 2013-04-25 Tokyo Metropolitan Univ 臓器保存装置
US9725687B2 (en) * 2011-12-09 2017-08-08 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
WO2013106908A1 (en) 2012-01-17 2013-07-25 University Of Manitoba Apparatus for testing, assessment, and maintenance of harvested hearts for transplanting
US11439143B2 (en) 2012-07-10 2022-09-13 Lifeline Scientific, Inc. Temperature sensing in organ preservation apparatus
US10602740B2 (en) 2012-07-10 2020-03-31 Lifeline Scientific, Inc. Organ perfusion apparatus with downstream flow control
US9560846B2 (en) 2012-08-10 2017-02-07 Paragonix Technologies, Inc. System for hypothermic transport of biological samples
US8785116B2 (en) 2012-08-10 2014-07-22 Paragonix Technologies, Inc. Methods for evaluating the suitability of an organ for transplant
US10433538B2 (en) 2012-10-12 2019-10-08 University of Pittsburgh—of the Commonwealth System of Higher Education Compositions and methods for organ preservation
CN102986649B (zh) * 2012-12-18 2014-07-16 武汉大学 一种用于自体肝移植术的离体连续灌注装置
CN107526936A (zh) * 2012-12-30 2017-12-29 上海联影医疗科技有限公司 肝灌注的定量测试方法
WO2015138832A1 (en) 2014-03-13 2015-09-17 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
ES3036002T3 (en) 2014-03-26 2025-09-11 Transmedics Inc Apparatus for maintenance of harvested hearts for transplanting
JP2017518301A (ja) 2014-06-02 2017-07-06 トランスメディクス， インク．Ｔｒａｎｓｍｅｄｉｃｓ， Ｉｎｃ． ｅｘ−ｖｉｖｏでの臓器管理システム
EP3177140B1 (en) * 2014-07-29 2022-07-06 21St Century Medicine, Inc. Method of introduction and removal of high concentrations of cryoprotectants by vascular perfusion
USD765874S1 (en) 2014-10-10 2016-09-06 Paragonix Technologies, Inc. Transporter for a tissue transport system
US11083191B2 (en) 2014-12-12 2021-08-10 Tevosol, Inc. Apparatus and method for organ perfusion
JP6934005B2 (ja) 2015-09-09 2021-09-08 トランスメディクス，インコーポレイテッド エキソビボ臓器管理システムのための大動脈カニューレ
US10091986B2 (en) 2016-05-09 2018-10-09 Xor-Labs Toronto Inc. Organ perfusion device and method
DK3462861T5 (da) 2016-05-30 2024-01-08 Transmedics Inc Fremgangsmåde til ex vivo-lungeventilati on med et varierende udvendigt tryk
EP3487295B1 (en) * 2016-07-22 2020-11-04 ETH Zürich Perfusion loop assembly for an ex-vivo liver perfusion
US11617832B2 (en) * 2016-08-17 2023-04-04 International Business Machines Corporation Portal system-based bionic pancreas
CN106508890A (zh) * 2016-10-28 2017-03-22 中山大学附属第医院 多器官保存装置
WO2018226993A1 (en) 2017-06-07 2018-12-13 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
US12058996B2 (en) 2017-06-14 2024-08-13 The General Hospital Corporation High subzero cryopreservation
WO2019141809A1 (en) 2018-01-19 2019-07-25 ETH Zürich Perfusion loop assembly for an ex-vivo liver perfusion and a method for ex-vivo liver perfusion
US10342737B1 (en) * 2018-03-22 2019-07-09 Maxq Research Llc Active monitoring system for thermally-managed transportation and storage of specific perishable products
US12167729B2 (en) 2018-05-30 2024-12-17 The General Hospital Corporation Cryopreservation of tissues and organs
WO2020252148A1 (en) 2019-06-11 2020-12-17 Paragonix Technologies, Inc. Organ transport container with antiviral therapy
JP7278898B2 (ja) * 2019-07-25 2023-05-22 株式会社Ｓｃｒｅｅｎホールディングス 灌流装置
CN110663680A (zh) * 2019-10-25 2020-01-10 上海长海医院 一种供肾的机器灌注保存及转运仪器
US11632951B2 (en) 2020-01-31 2023-04-25 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
JP7406211B2 (ja) * 2020-10-14 2023-12-27 株式会社島津製作所 臓器灌流装置および制御方法
IT202100022808A1 (it) * 2021-09-03 2023-03-03 Maria Cecilia Hospital S P A Dispositivo per il trattamento di tessuti biologici
USD1031028S1 (en) 2022-09-08 2024-06-11 Paragonix Technologies, Inc. Tissue suspension adaptor
WO2024261171A1 (en) 2023-06-22 2024-12-26 Aatec Medical Gmbh Recombinant aat from yeast to treat transplants
US12357533B2 (en) 2023-08-25 2025-07-15 Paragonix Technologies, Inc. Systems and methods for maintaining organ pressure
US12410408B2 (en) 2024-02-02 2025-09-09 Paragonix Technologies, Inc. Method for hypothermic transport of biological samples
USD1087382S1 (en) 2025-01-30 2025-08-05 Paragonix Technologies, Inc. Device for transporting a biological sample
CN120299665B (zh) * 2025-06-10 2025-09-16 四川省肿瘤医院 基于图像识别的肝脏灌注调控方法及系统

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE755423A (fr) 1969-10-06 1971-02-01 Baxter Laboratories Inc Procede et appareil pour la conservation d'organes
US3892628A (en) 1969-10-06 1975-07-01 Baxter Laboratories Inc Preservation of organs
US3995444A (en) * 1974-11-08 1976-12-07 American Hospital Supply Corporation Organ perfusion system
US4629686A (en) * 1982-02-19 1986-12-16 Endotronics, Inc. Apparatus for delivering a controlled dosage of a chemical substance
US4745759A (en) 1986-12-23 1988-05-24 Bauer Dan O Kidney preservation machine
US5051352A (en) 1987-10-07 1991-09-24 The Regents Of The University Of California Apparatus and method of preserving the viability of animal organs
US5069662A (en) * 1988-10-21 1991-12-03 Delcath Systems, Inc. Cancer treatment
JPH0653160B2 (ja) 1989-08-18 1994-07-20 呉羽化学工業株式会社 拍動発生方法及び装置
FR2667297B1 (fr) * 1990-09-28 1994-05-27 Electrolux Sarl Conteneur medical climatise.
US5157930A (en) 1991-04-22 1992-10-27 Mcghee Samuel C Organ preservation apparatus
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US5338662A (en) * 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
US5586438A (en) 1995-03-27 1996-12-24 Organ, Inc. Portable device for preserving organs by static storage or perfusion
AU728233B2 (en) * 1997-09-23 2001-01-04 Department Of Veteran Affairs, The Compositions, methods and devices for maintaining an organ
US6100082A (en) * 1997-09-23 2000-08-08 Hassanein; Waleed H. Perfusion apparatus and method including chemical compositions for maintaining an organ
US6014864A (en) 1998-03-16 2000-01-18 Life Science Holdings, Inc. Cryogenic fluid heat exchanger method and apparatus
EP2308296A3 (en) * 1998-09-29 2011-08-24 Organ Recovery Systems, Inc. System and method for holding an organ
US6209343B1 (en) 1998-09-29 2001-04-03 Life Science Holdings, Inc. Portable apparatus for storing and/or transporting biological samples, tissues and/or organs
US6673594B1 (en) 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US6977140B1 (en) * 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
US7749693B2 (en) * 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
GB9908335D0 (en) * 1999-04-12 1999-06-09 Univ Cambridge Tech Methods and means for extracorporeal organ perfusion
US6582953B2 (en) * 1999-04-14 2003-06-24 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US6492103B1 (en) * 2000-01-31 2002-12-10 Organ Recovery Systems, Inc. System for organ and tissue preservation and hypothermic blood substitution
JP2004529938A (ja) * 2001-05-04 2004-09-30 ブレオニクス，インコーポレーティッド 血液を含まない代謝支持システム用の器官室
JP2003206201A (ja) * 2001-12-28 2003-07-22 Katsutoshi Naruse 臓器収納装置を含む移植用臓器保存装置および該収納装置を含む人工臓器システム
JP4588633B2 (ja) * 2002-08-23 2010-12-01 オーガン リカヴァリー システムズ インコーポレイテッド 臓器移植用コネクタ
PL1613153T3 (pl) * 2003-04-04 2021-11-29 Organ Recovery Systems, Inc. Sposoby i aparat do perfuzji, diagnostyki, przechowywania i/lub transportu narządu lub tkanek
WO2004089085A2 (en) 2003-04-04 2004-10-21 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
CN1251586C (zh) 2003-11-20 2006-04-19 鞠烽炽 便携式肝脏体外灌注保存装置
US8741555B2 (en) * 2004-05-14 2014-06-03 Organ Recovery Systems, Inc. Apparatus and method for perfusion and determining the viability of an organ

Also Published As

Publication number Publication date
CN101677526A (zh) 2010-03-24
BRPI0808574B1 (pt) 2019-11-12
US20150189866A1 (en) 2015-07-09
JP2010520207A (ja) 2010-06-10
US20100028850A1 (en) 2010-02-04
EP2131650A1 (en) 2009-12-16
EP2131650B1 (en) 2017-11-29
WO2008108996A1 (en) 2008-09-12
BRPI0808574A2 (pt) 2014-09-09
US8986978B2 (en) 2015-03-24
EP2131650A4 (en) 2015-02-18
US9661843B2 (en) 2017-05-30
CA2679827A1 (en) 2008-09-12
JP5704818B2 (ja) 2015-04-22
HK1141679A1 (en) 2010-11-19
CN101677526B (zh) 2014-07-09
ES2659970T3 (es) 2018-03-20
CA2679827C (en) 2014-11-25

Similar Documents

Publication Publication Date Title
BRPI0808574B8 (pt) sistema de controle para pelo menos uma bomba para envio de um fluido em um aparelho de perfusão para pelo menos um órgão
MX394780B (es) Sistema, método y aparato para el monitoreo, regulación o control de flujo de fluido.
BR112018067685A2 (pt) conjunto, refrigerador, sistema para fornecer café, e, método para limpar um conjunto
BR112012033193A2 (pt) sistema de regulação da pressão de fluidos de barreira de motor e bomba, controlado por pressão diferencial.
WO2013001425A3 (en) Methods, circuits, devices, apparatuses, encasements and systems for identifying if a medical infusion system is decalibrated
EA201290747A1 (ru) Устройство и способ для регулирования расхода текучей среды
BR112015000496A2 (pt) aparelho de perfusão de órgão com controle de fluxo a jusante
MX2023005766A (es) Sistemas, dispositivos y metodos para bombeo de fluido, intercambio de calor, deteccion termica y deteccion de conductividad.
BR112016003170A2 (pt) aparelhos de bombeamento submarino e métodos relacionados
MX2023014904A (es) Sistema de hemodialisis
CL2014001632A1 (es) Un aparato para la regulación del caudal del fluido para su utilización en aplicaciones medicas, comprende un miembro de soporte alargado y curvado, elásticamente deformable, y un miembro de soporte opuesto configurado para posicionar el tubo contra el miembro de soporte alargado y curvado; sistema; método.
BRPI0907668B8 (pt) bomba de pressão reduzida acionada manualmente, aparelho de tratamento por pressão reduzida e sistema de tratamento por pressão reduzida
BRPI1015092B8 (pt) meio funcional externo, e, sistema com um aparelho de tratamento de sangue e pelo menos um meio funcional externo
BR112015016879A2 (pt) regulador fluido com válvula de desvio de pressurização rápida integrada
BR112015014944A2 (pt) válvula de retenção de excedente autorregulável
BR112017002576A2 (pt) sistema de circulação sanguínea.
BRPI0910750A2 (pt) conjunto de diafragma, regulador de pressão, e, dispositivo de controle de fluido.
BR112017022016A2 (pt) unidade para a regulagem ou controle de uma pressão de fluido
BR112015017587A2 (pt) desvio de fluxo em um sistema de circulação de fluido de perfuração para regular pressão de fluido de perfuração
BRPI0811580A2 (pt) Método para regular a pressão de um fluido de barreira e um dispositivo de bombeamento para um método deste tipo
BR112018010053A2 (pt) sistemas de avaliação de confiabilidade para acionar dispositivos hidraulicamente acionados e métodos relacionados
CO2019008695A2 (es) Técnica de compensación de velocidad de flujo en función del volumen para terapia de infusión
BR102017016863A8 (pt) Sistema de variação de fluxo
MX2017016166A (es) Valvula de aguja.
BR112014027703A2 (pt) aparelho, sistemas e métodos de amostragem de ambiente de formação

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A01N 1/00 , A01N 1/02

Ipc: A61M 1/10 (1985.01), A61N 1/02 (1968.09), A61N 1/0

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/11/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/11/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 29/02/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO