[go: up one dir, main page]

BRPI0601725A - compostos de fenilpiridilpiperazina, um processo para sua preparação e composições farmacêuticas contendo-os - Google Patents

compostos de fenilpiridilpiperazina, um processo para sua preparação e composições farmacêuticas contendo-os

Info

Publication number
BRPI0601725A
BRPI0601725A BRPI0601725-8A BRPI0601725A BRPI0601725A BR PI0601725 A BRPI0601725 A BR PI0601725A BR PI0601725 A BRPI0601725 A BR PI0601725A BR PI0601725 A BRPI0601725 A BR PI0601725A
Authority
BR
Brazil
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
compounds
group
Prior art date
Application number
BRPI0601725-8A
Other languages
English (en)
Inventor
Patrice Desos
Alexis Cordi
Pierre Lestage
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of BRPI0601725A publication Critical patent/BRPI0601725A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

COMPOSTOS DE FENILPIRIDILPIPERAZINA, UM PROCESSO PARA SUA PREPARAçãO E COMPOSIçõES FARMACêUTICAS CONTENDO-OS. Compostos de fórmula (i): em que: R~ 1~ representa um grupo de NR~ 3~SO~ 2~R~ 4~ em que: R~ 3~ representa um átomo de hidrogênio ou um grupo de alquila, R~ 4~ representa um grupo de alquila, grupo de arila ou grupo de NR~ 5~R~ 6~, R~ 2~ representa um grupo de alquila, cicloalquila ou cicloalquilalquila. Medicamentos.
BRPI0601725-8A 2005-05-12 2006-05-12 compostos de fenilpiridilpiperazina, um processo para sua preparação e composições farmacêuticas contendo-os BRPI0601725A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0504757A FR2885615B1 (fr) 2005-05-12 2005-05-12 Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BRPI0601725A true BRPI0601725A (pt) 2007-05-08

Family

ID=35677562

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0601725-8A BRPI0601725A (pt) 2005-05-12 2006-05-12 compostos de fenilpiridilpiperazina, um processo para sua preparação e composições farmacêuticas contendo-os

Country Status (20)

Country Link
US (1) US7494995B2 (pt)
EP (1) EP1721896A1 (pt)
JP (1) JP2006342158A (pt)
KR (1) KR100807482B1 (pt)
CN (1) CN100540536C (pt)
AR (1) AR054120A1 (pt)
AU (1) AU2006201993A1 (pt)
BR (1) BRPI0601725A (pt)
CA (1) CA2546387A1 (pt)
EA (1) EA011165B1 (pt)
FR (1) FR2885615B1 (pt)
GE (1) GEP20084503B (pt)
MA (1) MA28325A1 (pt)
MY (1) MY140963A (pt)
NO (1) NO20062100L (pt)
NZ (1) NZ547121A (pt)
SG (1) SG127800A1 (pt)
UA (1) UA87283C2 (pt)
WO (1) WO2006120348A1 (pt)
ZA (1) ZA200603809B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
US8501739B2 (en) 2005-07-04 2013-08-06 High Point Pharmaceuticals, Llc Medicaments
AU2007267197B2 (en) 2006-05-29 2011-12-01 High Point Pharmaceuticals, Llc 3- (1, 3-Benzodioxol-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine H3 receptor antagonist
EP2014656A3 (en) 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
CN103209960A (zh) 2010-07-26 2013-07-17 百时美施贵宝公司 用作cyp17抑制剂的磺酰胺化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019574A (en) * 1988-09-30 1991-05-28 Chugai Seiyaku Kabushiki Kaisha 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function
JP2563402Y2 (ja) * 1989-09-28 1998-02-25 株式会社小松製作所 ディーゼルエンジンのピストン
JPH06501019A (ja) * 1990-09-13 1994-01-27 スミスクライン・ビーチャム・コーポレイション ピリジルチオまたはピリジルオキシアルカン酸
WO1998015548A1 (en) * 1996-10-04 1998-04-16 Novo Nordisk A/S 1,4-disubstituted piperazines
US6340759B1 (en) * 1997-10-02 2002-01-22 Eisai Co., Ltd. Fused pyridine derivatives
SK285198B6 (sk) * 1997-10-27 2006-08-03 Neurosearch A/S Homopiperazínový derivát, farmaceutická kompozícia obsahujúca tento derivát a jeho použitie
GB9919776D0 (en) * 1998-08-31 1999-10-27 Zeneca Ltd Compoujnds
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines

Also Published As

Publication number Publication date
CN100540536C (zh) 2009-09-16
FR2885615A1 (fr) 2006-11-17
NZ547121A (en) 2007-05-31
EP1721896A1 (fr) 2006-11-15
NO20062100L (no) 2006-11-13
JP2006342158A (ja) 2006-12-21
US7494995B2 (en) 2009-02-24
WO2006120348A1 (fr) 2006-11-16
ZA200603809B (en) 2007-08-29
CA2546387A1 (fr) 2006-11-12
MY140963A (en) 2010-02-12
UA87283C2 (ru) 2009-07-10
CN1896062A (zh) 2007-01-17
FR2885615B1 (fr) 2007-06-22
MA28325A1 (fr) 2006-12-01
HK1096097A1 (zh) 2007-05-25
GEP20084503B (en) 2008-10-10
KR100807482B1 (ko) 2008-02-25
KR20060117262A (ko) 2006-11-16
EA200600761A1 (ru) 2006-12-29
US20060258671A1 (en) 2006-11-16
EA011165B1 (ru) 2009-02-27
AR054120A1 (es) 2007-06-06
SG127800A1 (en) 2006-12-29
AU2006201993A1 (en) 2006-11-30

Similar Documents

Publication Publication Date Title
EA200701176A1 (ru) Новые соединения нафталина, способ их получения и фармацевтические композиции, содержащие их
BRPI0900983A2 (pt) compostos de diometina, processo para sua preparação e composições farmacêuticas contendo os mesmos
BRPI0417708A (pt) derivados organofosfóricos dos indazóis e sua utilização como inibidores das proteìnas quinases
BR0314379A (pt) Quinazolinonas espirocondensadas e a sua utilização como inibidores de fosfodiesterase
BR0206433A (pt) Composto, composição farmacêutica, processo para a prepapação de um composto, e, uso de um composto
BR0212185A (pt) Compostos e métodos para a preparação de compostos
BRPI0418031A (pt) inibidores de quinase fosfonato-substituìdos
BRPI0510410A (pt) compostos orgánicos
BRPI0508047A (pt) derivados de alquilpiperazina-e alquil-homopiperazina-carboxilatos, o respectivo preparo e a respectiva aplicação como inibidores da enzima faah
BRPI0416287A (pt) compostos, processo para a manufatura dos mesmos, composições farmacêuticas que os compreendem, método para o tratamento e/ou prevenção de enfermidades que são moduladas por inibidores de accß e sua utilização
BRPI0601725A (pt) compostos de fenilpiridilpiperazina, um processo para sua preparação e composições farmacêuticas contendo-os
BRPI0403028A (pt) Compostos heterocìclicos de oxima, processo para sua preparação e composições farmacêuticas contendo os mesmos
BRPI0508102A (pt) inibidores de caspase e usos dos mesmos
BRPI0510221A (pt) composto de aril cetona, composição, forma de dosagem unitária, uso da composição e método para preparar uma composição
BR0016921A (pt) Tetrahidropiridinas, processo para sua preparação e composições farmacêuticas que as contêm
BR0111669A (pt) Novos compostos
BR0308807A (pt) Compostos tiazol-2-il-imina como inibidores de pde-7
BRPI0412826A (pt) n-[3-(3-substituìdo-pirazolo[1,5-a]pirimidin-7-il)fenil]-s ulfonamidas e compositions e métodos relacionados a ele
BR0106248A (pt) Inibidores de metaloprotease, processo para a sua preparação e composições farmacêuticas contendo os mesmos
BRPI0504780A (pt) compostos de benzotiadiazina, processo para sua preparação e composições farmacêuticas contendo os mesmos
EA200000068A3 (ru) Новые цианоиндольные соединения, являющиеся ингибиторами повторного захвата серотонина, способ их получения и фармацевтические композиции, содержащие их
BR0304575A (pt) Compostos [3,4-a:3,4-c]carbazol, processo para sua preparação e composições farmacêuticas contendo os mesmos
EA200600760A1 (ru) Новые соединения фенилпиридилпиперазина, способ их получения и фармацевтические композиции, содержащие их
UA91646C2 (ru) Соединения индола, способ их получения и фармацевтическая композиция (варианты), которая их содержит
BR0202674A (pt) Compostos de benzenossulfonamida, processo para a sua preparação e composições farmacêuticas contendo os mesmos

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.