BRPI0606976A2 - processo para preparação de intermediários - Google Patents
processo para preparação de intermediáriosInfo
- Publication number
- BRPI0606976A2 BRPI0606976A2 BRPI0606976-2A BRPI0606976A BRPI0606976A2 BR PI0606976 A2 BRPI0606976 A2 BR PI0606976A2 BR PI0606976 A BRPI0606976 A BR PI0606976A BR PI0606976 A2 BRPI0606976 A2 BR PI0606976A2
- Authority
- BR
- Brazil
- Prior art keywords
- intermediates
- formula
- preparation
- azeotropic distillation
- intermediate compounds
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000010533 azeotropic distillation Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N N-phenyl amine Natural products NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 abstract 1
- 125000002490 anilino group Chemical class [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 238000006193 diazotization reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000197 pyrolysis Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
- C07C25/02—Monocyclic aromatic halogenated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B39/00—Halogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCESSO PARA A PREPARAçãO DE INTERMEDIáRIOS. A presente invenção refere-se a um processo para a produção de compostos intermediários de fórmula I no qual os substituintes são conforme definidos acima. O processo compreende reagir uma anilina substituida com HX aquoso, seguido pela remoção de água por destilação azeotrópica e diazotização e pirólise com um nitrito orgânico em temperaturas elevadas na auséncia de um catalisador de cobre. Alternativamente, HX gasoso pode ser usado para substituir HX aquoso no processo. Conseqúentemente, uma etapa de remoção de água por destilação azeotrópica pode ser eliminada, Os compostos intermediários de fórmula 1 são adequados como intermediários na preparação de derivados de 3-hidróxi-4-aril-5-oxopirazolina herbicidamente ativos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65117505P | 2005-02-09 | 2005-02-09 | |
| PCT/EP2006/001068 WO2006084663A1 (en) | 2005-02-09 | 2006-02-07 | Process for the preparation of intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0606976A2 true BRPI0606976A2 (pt) | 2009-07-28 |
| BRPI0606976B1 BRPI0606976B1 (pt) | 2015-12-08 |
Family
ID=36390191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0606976A BRPI0606976B1 (pt) | 2005-02-09 | 2006-02-07 | processo para a preparação de intermediários |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8030529B2 (pt) |
| EP (1) | EP1848678B1 (pt) |
| JP (2) | JP5254625B2 (pt) |
| KR (1) | KR101355873B1 (pt) |
| CN (2) | CN102603444A (pt) |
| AR (1) | AR053123A1 (pt) |
| AU (1) | AU2006212397B2 (pt) |
| BR (1) | BRPI0606976B1 (pt) |
| CA (1) | CA2596590C (pt) |
| DK (1) | DK1848678T3 (pt) |
| EA (1) | EA013842B1 (pt) |
| ES (1) | ES2546960T3 (pt) |
| HU (1) | HUE027652T2 (pt) |
| IL (1) | IL184715A (pt) |
| MX (1) | MX2007009341A (pt) |
| PL (1) | PL1848678T3 (pt) |
| PT (1) | PT1848678E (pt) |
| TW (1) | TWI360533B (pt) |
| UA (1) | UA89218C2 (pt) |
| WO (1) | WO2006084663A1 (pt) |
| ZA (1) | ZA200705880B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101492343B (zh) * | 2008-12-30 | 2011-08-10 | 中钢集团鞍山热能研究院有限公司 | 3,5-二甲基溴苯的制备方法 |
| CN102395546B (zh) | 2009-03-12 | 2014-03-12 | 拜耳作物科学公司 | 制备氯代和溴代芳烃的方法 |
| WO2012165648A1 (en) | 2011-05-30 | 2012-12-06 | Sumitomo Chemical Company, Limited | Cyclohexanone compounds and herbicides comprising the same |
| AU2013342504B2 (en) | 2012-11-08 | 2016-07-28 | Sumitomo Chemical Company, Limited | Herbicide composition |
| CN109476588A (zh) | 2016-07-22 | 2019-03-15 | 先正达参股股份有限公司 | 制备苯基丙二酸二腈的方法 |
| CN109336762B (zh) * | 2018-11-30 | 2021-03-16 | 江苏富鼎化学有限公司 | 2-(2,6-二乙基-4-甲基苯)丙二酸二乙酯的合成方法 |
| CN114907181B (zh) * | 2021-02-09 | 2024-04-23 | 北京颖泰嘉和生物科技股份有限公司 | 用于桑德迈尔反应的装置和连续制备2,6-二乙基-4-甲基溴苯的方法 |
| WO2023044364A1 (en) | 2021-09-15 | 2023-03-23 | Enko Chem, Inc. | Protoporphyrinogen oxidase inhibitors |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE600706C (de) | 1933-03-24 | 1934-07-30 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung aromatischer, im Kern fluorierter Verbindungen |
| DE1695659B1 (de) | 1967-12-18 | 1971-12-16 | Ruetgerswerke Ag | Verfahren zur Herstellung von 2-Chlorpyridinen |
| JPS59112965A (ja) | 1982-12-20 | 1984-06-29 | Koei Chem Co Ltd | ４−クロルピリジン塩酸塩の製造法 |
| FR2586247B1 (fr) | 1985-08-19 | 1987-11-20 | Rhone Poulenc Spec Chim | Procede de preparation de composes aromatiques fluores |
| US4822927A (en) * | 1987-11-24 | 1989-04-18 | Mallinckrodt, Inc. | Continuous decomposition of diazonium fluorides |
| JPH01283230A (ja) | 1988-05-09 | 1989-11-14 | Mitsui Toatsu Chem Inc | 芳香族弗素化合物の製造方法 |
| CA2106302A1 (en) | 1991-03-19 | 1992-09-20 | Frederik Cederbaum | Herbicidally, acaricidally and insecticidally active compounds |
| DE4109208A1 (de) | 1991-03-21 | 1992-09-24 | Bayer Ag | 3-hydroxy-4-aryl-5-oxo-pyrazolin-derivate |
| DE4111214A1 (de) | 1991-04-06 | 1992-10-08 | Bayer Ag | Verfahren zur herstellung von 2-chlorpyridinen |
| AU7072694A (en) | 1993-07-05 | 1995-02-06 | Bayer Aktiengesellschaft | Substituted aryl-keto-enolic heterocycles |
| CA2210286A1 (en) * | 1995-01-13 | 1996-07-18 | Novartis Ag | 4-aryl- and 4-heteroaryl -5-oxopyrazoline derivatives having pesticidal properties |
| ES2224156T3 (es) | 1995-02-13 | 2005-03-01 | Bayer Cropscience Ag | 1,2-cetoenoles heterociclicos 2-fenil- substituidos como herbicidas y pesticidas. |
| DE19517186A1 (de) * | 1995-05-11 | 1996-11-14 | Bayer Ag | Verfahren zur Herstellung substituierter 2-Fluor-pyrimidine |
| EP0835243B1 (de) | 1995-06-30 | 2003-01-29 | Bayer CropScience AG | Dialkyl-halogenphenylsubstituierte ketoenole zur verwendung als herbizide und pestizide |
| CZ301369B6 (cs) | 1998-03-13 | 2010-02-03 | Syngenta Participations Ag | Herbicidne aktivní deriváty 3-hydroxy-4-aryl-5-oxopyrazolinu |
| UA73511C2 (en) | 1999-06-16 | 2005-08-15 | Syngenta Participations Ag | Herbicide compounds, a method for the preparation thereof and intermediary compounds |
| CA2368827A1 (en) | 1999-06-16 | 2000-12-28 | Syngenta Participations Ag | New intermediates |
| DE60220658T2 (de) | 2001-04-05 | 2008-02-21 | Sumitomo Chemical Co., Ltd. | Verfahren zur produktion von 2,6-dihalogenopurinen |
| AR042282A1 (es) | 2002-12-05 | 2005-06-15 | Syngenta Participations Ag | Proceso para la preparacion de dinitrilos de acido fenilmalonico |
-
2006
- 2006-02-07 PT PT67044438T patent/PT1848678E/pt unknown
- 2006-02-07 TW TW095103994A patent/TWI360533B/zh active
- 2006-02-07 PL PL06704443T patent/PL1848678T3/pl unknown
- 2006-02-07 KR KR1020077018180A patent/KR101355873B1/ko not_active Expired - Lifetime
- 2006-02-07 CN CN2012100205799A patent/CN102603444A/zh active Pending
- 2006-02-07 ES ES06704443.8T patent/ES2546960T3/es not_active Expired - Lifetime
- 2006-02-07 MX MX2007009341A patent/MX2007009341A/es active IP Right Grant
- 2006-02-07 UA UAA200709950A patent/UA89218C2/ru unknown
- 2006-02-07 CA CA2596590A patent/CA2596590C/en not_active Expired - Lifetime
- 2006-02-07 US US11/815,458 patent/US8030529B2/en active Active
- 2006-02-07 HU HUE06704443A patent/HUE027652T2/en unknown
- 2006-02-07 AU AU2006212397A patent/AU2006212397B2/en not_active Expired
- 2006-02-07 EA EA200701616A patent/EA013842B1/ru not_active IP Right Cessation
- 2006-02-07 JP JP2007553565A patent/JP5254625B2/ja not_active Expired - Lifetime
- 2006-02-07 DK DK06704443.8T patent/DK1848678T3/en active
- 2006-02-07 EP EP06704443.8A patent/EP1848678B1/en not_active Expired - Lifetime
- 2006-02-07 BR BRPI0606976A patent/BRPI0606976B1/pt active IP Right Grant
- 2006-02-07 AR ARP060100436A patent/AR053123A1/es active IP Right Grant
- 2006-02-07 CN CN2006800044338A patent/CN101115704B/zh not_active Expired - Lifetime
- 2006-02-07 WO PCT/EP2006/001068 patent/WO2006084663A1/en not_active Ceased
-
2007
- 2007-07-18 ZA ZA200705880A patent/ZA200705880B/xx unknown
- 2007-07-19 IL IL184715A patent/IL184715A/en active IP Right Grant
-
2012
- 2012-06-04 JP JP2012127185A patent/JP5411319B2/ja not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/02/2006, OBSERVADAS AS CONDICOES LEGAIS. |