BRPI0605918A2 - rosuvastatina cálcica com um baixo conteúdo de sal - Google Patents
rosuvastatina cálcica com um baixo conteúdo de salInfo
- Publication number
- BRPI0605918A2 BRPI0605918A2 BRPI0605918-0A BRPI0605918A BRPI0605918A2 BR PI0605918 A2 BRPI0605918 A2 BR PI0605918A2 BR PI0605918 A BRPI0605918 A BR PI0605918A BR PI0605918 A2 BRPI0605918 A2 BR PI0605918A2
- Authority
- BR
- Brazil
- Prior art keywords
- low salt
- salt calcium
- calcium rosuvastatin
- rosuvastatin
- calcium
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 title 1
- 229960000672 rosuvastatin Drugs 0.000 title 1
- 229960004796 rosuvastatin calcium Drugs 0.000 abstract 2
- LALFOYNTGMUKGG-BGRFNVSISA-L rosuvastatin calcium Chemical compound [Ca+2].CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O.CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O LALFOYNTGMUKGG-BGRFNVSISA-L 0.000 abstract 2
- 239000006227 byproduct Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
ROSUVASTATINA CáLCICA COM UM BAIXO CONTEúDO DE SAL. São fornecidos rosuvastatina cálcica com um baixo conteúdo de subproduto de sal e processos para preparação dessa rosuvastatina cálcica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70906505P | 2005-08-16 | 2005-08-16 | |
| PCT/US2006/032165 WO2007022366A2 (en) | 2005-08-16 | 2006-08-16 | Rosuvastatin calcium with a low salt by-product content |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0605918A2 true BRPI0605918A2 (pt) | 2009-05-26 |
Family
ID=37507612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0605918-0A BRPI0605918A2 (pt) | 2005-08-16 | 2006-08-16 | rosuvastatina cálcica com um baixo conteúdo de sal |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20070099994A1 (pt) |
| EP (1) | EP1919880A2 (pt) |
| JP (1) | JP2008513520A (pt) |
| KR (2) | KR20090108671A (pt) |
| BR (1) | BRPI0605918A2 (pt) |
| CA (1) | CA2619867A1 (pt) |
| IL (1) | IL188648A0 (pt) |
| MX (1) | MX2007004423A (pt) |
| TW (1) | TW200800918A (pt) |
| WO (1) | WO2007022366A2 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070099994A1 (en) * | 2005-08-16 | 2007-05-03 | Valerie Niddam-Hildesheim | Rosuvastatin calcium with a low salt content |
| EP2079712A2 (en) * | 2006-10-31 | 2009-07-22 | Aurobindo Pharma Limited | An improved process for preparing rosuvastatin calcium |
| ATE553098T1 (de) * | 2007-02-08 | 2012-04-15 | Aurobindo Pharma Ltd | Verfahren zur herstellung von rosuvastatin- calcium |
| EP2172471B1 (en) * | 2007-04-18 | 2013-03-27 | Teva Pharmaceutical Industries, Ltd. | A process for preparing intermediates of HMG-CoA reductase inhibitors |
| WO2009009153A1 (en) * | 2007-07-12 | 2009-01-15 | Teva Pharmaceutical Industries Ltd. | Purification of rosuvastatin intermediate by thin film evaporation and chemical method |
| US8716305B2 (en) | 2011-04-18 | 2014-05-06 | Basf Se | Multicomponent crystalline system of rosuvastatin calcium salt and vanillin |
| KR102059995B1 (ko) | 2017-09-20 | 2019-12-27 | 주식회사 큐브인스트루먼트 | 저온 멸균 장치를 이용한 멸균 방법 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2732309A (en) * | 1952-08-28 | 1956-01-24 | Process for the production of cold | |
| JP2648897B2 (ja) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | ピリミジン誘導体 |
| US6777552B2 (en) * | 2001-08-16 | 2004-08-17 | Teva Pharmaceutical Industries, Ltd. | Processes for preparing calcium salt forms of statins |
| WO2003097614A2 (en) * | 2002-05-21 | 2003-11-27 | Ranbaxy Laboratories Limited | Process for the preparation of rosuvastatin |
| GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
| GB0312896D0 (en) * | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
| CA2657076A1 (en) * | 2003-08-28 | 2005-03-17 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of rosuvastatin calcium |
| US20070191318A1 (en) * | 2003-10-22 | 2007-08-16 | Yatendra Kumar | Process for the preparation of amorphous rosuvastatin calcium |
| WO2005054207A1 (en) | 2003-12-04 | 2005-06-16 | Glenmark Pharmaceuticals Limited | Process for the preparation of pyrimidine derivatives |
| US20070099994A1 (en) * | 2005-08-16 | 2007-05-03 | Valerie Niddam-Hildesheim | Rosuvastatin calcium with a low salt content |
-
2006
- 2006-08-16 US US11/506,062 patent/US20070099994A1/en not_active Abandoned
- 2006-08-16 BR BRPI0605918-0A patent/BRPI0605918A2/pt not_active IP Right Cessation
- 2006-08-16 CA CA002619867A patent/CA2619867A1/en not_active Abandoned
- 2006-08-16 KR KR1020097019784A patent/KR20090108671A/ko not_active Ceased
- 2006-08-16 EP EP06801755A patent/EP1919880A2/en not_active Withdrawn
- 2006-08-16 TW TW095130086A patent/TW200800918A/zh unknown
- 2006-08-16 WO PCT/US2006/032165 patent/WO2007022366A2/en not_active Ceased
- 2006-08-16 JP JP2007532703A patent/JP2008513520A/ja active Pending
- 2006-08-16 KR KR1020077007698A patent/KR20070065359A/ko not_active Ceased
- 2006-08-16 MX MX2007004423A patent/MX2007004423A/es not_active Application Discontinuation
-
2008
- 2008-01-08 IL IL188648A patent/IL188648A0/en unknown
-
2009
- 2009-05-04 US US12/387,605 patent/US20090240054A1/en not_active Abandoned
- 2009-05-04 US US12/387,634 patent/US20090215806A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL188648A0 (en) | 2008-08-07 |
| US20070099994A1 (en) | 2007-05-03 |
| US20090240054A1 (en) | 2009-09-24 |
| WO2007022366A8 (en) | 2007-12-06 |
| JP2008513520A (ja) | 2008-05-01 |
| EP1919880A2 (en) | 2008-05-14 |
| CA2619867A1 (en) | 2007-02-22 |
| WO2007022366A2 (en) | 2007-02-22 |
| MX2007004423A (es) | 2007-06-14 |
| KR20070065359A (ko) | 2007-06-22 |
| WO2007022366B1 (en) | 2007-07-12 |
| TW200800918A (en) | 2008-01-01 |
| KR20090108671A (ko) | 2009-10-15 |
| WO2007022366A3 (en) | 2007-05-31 |
| US20090215806A1 (en) | 2009-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2267 DE 17/06/2014. |