[go: up one dir, main page]

BRPI0516819A - triazolopyridine derivatives and antibacterial agents - Google Patents

triazolopyridine derivatives and antibacterial agents

Info

Publication number
BRPI0516819A
BRPI0516819A BRPI0516819-8A BRPI0516819A BRPI0516819A BR PI0516819 A BRPI0516819 A BR PI0516819A BR PI0516819 A BRPI0516819 A BR PI0516819A BR PI0516819 A BRPI0516819 A BR PI0516819A
Authority
BR
Brazil
Prior art keywords
antibacterial agents
triazolopyridine derivatives
triazolopyridine
derivatives
antimicrobial
Prior art date
Application number
BRPI0516819-8A
Other languages
Portuguese (pt)
Inventor
David Charles Donnell Butler
Huifen Chen
Vishnumurthy Ramachandra Hegde
Chris Limberakis
Ravindra Madhukar Rasne
Richard John Sciotti
Jeremy Tyson Starr
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BRPI0516819A publication Critical patent/BRPI0516819A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

DERIVADOS DE TRIAZOLOPIRIDINA E AGENTES ANTIBACTERIANOS. A presente invenção diz respeito a uma classe inédita de derivados de triazolopiridina, ao seu uso como antimicrobiano e aos produtos farmacêuticos contendo esses compostos.Triazolopyridine derivatives and anti-bacterial agents. The present invention relates to an unprecedented class of triazolopyridine derivatives, their use as an antimicrobial and pharmaceuticals containing such compounds.

BRPI0516819-8A 2004-10-07 2005-09-23 triazolopyridine derivatives and antibacterial agents BRPI0516819A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61693104P 2004-10-07 2004-10-07
US71059205P 2005-08-24 2005-08-24
PCT/IB2005/003112 WO2006038116A2 (en) 2004-10-07 2005-09-23 Triazolopyridine derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
BRPI0516819A true BRPI0516819A (en) 2008-09-23

Family

ID=35998551

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516819-8A BRPI0516819A (en) 2004-10-07 2005-09-23 triazolopyridine derivatives and antibacterial agents

Country Status (7)

Country Link
US (1) US7524860B2 (en)
EP (1) EP1799680A2 (en)
JP (1) JP2008515874A (en)
BR (1) BRPI0516819A (en)
CA (1) CA2582482A1 (en)
MX (1) MX2007004179A (en)
WO (1) WO2006038116A2 (en)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572807B2 (en) 2005-06-09 2009-08-11 Bristol-Myers Squibb Company Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
US7579360B2 (en) 2005-06-09 2009-08-25 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
CA2656855A1 (en) * 2006-07-12 2008-01-17 Christoph Luthy Triazolopyridine derivatives as herbicides
EP1894931A1 (en) * 2006-08-30 2008-03-05 Cellzome Ag Triazole derivatives as kinase inhibitors
SG174086A1 (en) * 2006-08-30 2011-09-29 Cellzome Ltd Triazole derivatives as kinase inhibitors
EP2096923B1 (en) * 2006-11-27 2014-01-22 H. Lundbeck A/S Heteroaryl amide derivatives
UA96964C2 (en) 2006-12-04 2011-12-26 Астразенека Аб Antibacterial polycyclic urea compounds
CN101772498A (en) 2007-04-10 2010-07-07 H.隆德贝克有限公司 Heteroarylamide analogs as P2X7 antagonists
US8829190B2 (en) 2007-04-16 2014-09-09 Leo Pharma A/S Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases
CN101801966A (en) * 2007-07-18 2010-08-11 诺瓦提斯公司 Bicyclic heteroaryl compounds and their use as kinase inhibitors
US8119658B2 (en) 2007-10-01 2012-02-21 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
EA201000797A1 (en) 2007-11-27 2011-02-28 Целльзом Лимитид AMINOTRIAZOLES AS PI3K INHIBITORS
US20110105457A1 (en) * 2008-04-18 2011-05-05 Shionogi & Co., Ltd. Heterocyclic compound having inhibitory activity on pi3k
CA2727036C (en) 2008-06-20 2017-03-21 Genentech, Inc. Triazolopyridine jak inhibitor compounds and methods
SG178807A1 (en) 2008-06-20 2012-03-29 Genentech Inc Triazolopyridine jak inhibitor compounds and methods
JPWO2009157423A1 (en) 2008-06-24 2011-12-15 財団法人乙卯研究所 Oxazolidinone derivatives having fused rings
WO2010007100A1 (en) * 2008-07-15 2010-01-21 Cellzome Ltd 7-substituted amino triazoles as pi3k inhibitors
JO3041B1 (en) 2008-07-25 2016-09-05 Galapagos Nv Novel compounds useful for the treatment of degenerative and inflammatory diseases
WO2010010189A1 (en) * 2008-07-25 2010-01-28 Galapagos Nv Novel compounds useful for the treatment of degenerative and inflammatory diseases
WO2010010184A1 (en) * 2008-07-25 2010-01-28 Galapagos Nv [1, 2, 4] triazolo [1, 5-a] pyridines as jak inhibitors
WO2010010187A1 (en) * 2008-07-25 2010-01-28 Galapagos Nv Novel compounds useful for the treatment of degenerative and inflammatory diseases
TWI453207B (en) 2008-09-08 2014-09-21 Signal Pharm Llc Aminotriazolopyridines, compositions thereof, and methods of treatment therewith
WO2010057877A1 (en) * 2008-11-18 2010-05-27 Cellzome Limited 7-pyridinyl- or phenyl- substituted triazolo [1, 5 -a] pyridines as pi3k inhibitors
WO2010092015A1 (en) 2009-02-10 2010-08-19 Cellzome Limited Urea triazololo [1, 5-a] pyridine derivatives as pi3k inhibitors
BRPI1009637A2 (en) 2009-06-05 2019-04-30 Cephalon, Inc compound, composition and use of a compound
TWI462920B (en) 2009-06-26 2014-12-01 葛萊伯格有限公司 Novel compound useful for the treatment of degenerative and inflammatory diseases
JO3030B1 (en) 2009-06-26 2016-09-05 Galapagos Nv Novel Compound Useful for the Treatment of Degenerative and Inflammatory Diseases
EP2343297A1 (en) 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
EP2343294A1 (en) 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
MX2012010666A (en) 2010-03-31 2012-10-05 Actelion Pharmaceuticals Ltd Antibacterial isoquinolin-3-ylurea derivatives.
WO2012068096A2 (en) 2010-11-15 2012-05-24 Exelixis, Inc. Benzoxazepines as inhibitors of pi3k/mtor and methods of their use and manufacture
AR088729A1 (en) 2011-03-29 2014-07-02 Actelion Pharmaceuticals Ltd DERIVATIVES OF 3-UREIDOISOQUINOLIN-8-ILO AND A PHARMACEUTICAL COMPOSITION
ES2605946T3 (en) 2012-03-14 2017-03-17 Bayer Intellectual Property Gmbh Imidazopyridazines substituted
WO2013149118A1 (en) * 2012-03-30 2013-10-03 Monsanto Technology Llc Alcohol reformer for reforming alcohol to mixture of gas including hydrogen
BR112015000308A2 (en) * 2012-07-10 2017-06-27 Bayer Pharma AG method for preparing substituted triazolopyridines
IN2015DN00202A (en) 2012-07-12 2015-06-12 Chiesi Farma Spa
JP2016526534A (en) 2013-06-11 2016-09-05 バイエル・ファルマ・アクティエンゲゼルシャフト Prodrug derivatives of substituted triazolopyridines
GB201402070D0 (en) 2014-02-07 2014-03-26 Galapagos Nv Pharmaceutical compositions for the treatment of inflammatory disorders
GB201402071D0 (en) 2014-02-07 2014-03-26 Galapagos Nv Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
SG10201806849WA (en) 2014-02-13 2018-09-27 Incyte Corp Cyclopropylamines as lsd1 inhibitors
CN106488915B (en) 2014-02-13 2020-10-02 因赛特公司 Cyclopropylamines as LSD1 inhibitors
US9527835B2 (en) 2014-02-13 2016-12-27 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
TW201613860A (en) 2014-02-13 2016-04-16 Incyte Corp Cyclopropylamines as LSD1 inhibitors
US9758523B2 (en) 2014-07-10 2017-09-12 Incyte Corporation Triazolopyridines and triazolopyrazines as LSD1 inhibitors
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
US9695167B2 (en) 2014-07-10 2017-07-04 Incyte Corporation Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors
US9695168B2 (en) 2014-07-10 2017-07-04 Incyte Corporation Substituted imidazo[1,5-α]pyridines and imidazo[1,5-α]pyrazines as LSD1 inhibitors
US9944647B2 (en) 2015-04-03 2018-04-17 Incyte Corporation Heterocyclic compounds as LSD1 inhibitors
CN105175411B (en) * 2015-05-06 2017-08-15 西安交通大学 The synthetic method of a kind of carbamide compounds and its salt compounds and application
UA126277C2 (en) 2015-08-12 2022-09-14 Інсайт Корпорейшн LSD1 INHIBITOR SALTS
BR112018071585B1 (en) 2016-04-22 2024-01-02 Incyte Corporation FORMULATIONS OF AN LSD1 INHIBITOR, THEIR USES AND METHOD OF PREPARATION THEREOF
RU2019133662A (en) 2017-03-24 2021-04-26 Тайсо Фармасьютикал Ко., Лтд. DERIVATIVE OF 2 (1H) -QUINOLINONE
GB201808575D0 (en) 2018-05-24 2018-07-11 Galapagos Nv Methods for the treatment of psoriatic arthrits
US10968200B2 (en) 2018-08-31 2021-04-06 Incyte Corporation Salts of an LSD1 inhibitor and processes for preparing the same
AU2020246313B2 (en) * 2019-03-22 2022-08-04 Genfleet Therapeutics (Shanghai) Inc. Substituted heterocyclic amide compound and preparation method therefor and pharmaceutical use thereof
CN119841829A (en) * 2023-10-18 2025-04-18 中国科学院合肥物质科学研究院 Compounds for the treatment of PI3K gamma mediated diseases and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
DK1330458T3 (en) * 2000-11-03 2009-09-21 Dow Agrosciences Llc N- (1,2,4-triazoloazinyl) thiophenesulfonamide compounds as herbicides
EP1341769B1 (en) 2000-12-15 2007-10-17 Vertex Pharmaceuticals Incorporated Bacterial gyrase inhibitors and uses thereof
WO2004014908A1 (en) 2002-08-13 2004-02-19 Warner-Lambert Company Llc Heterobicylcic metalloproteinase inhibitors

Also Published As

Publication number Publication date
US20080021059A1 (en) 2008-01-24
JP2008515874A (en) 2008-05-15
EP1799680A2 (en) 2007-06-27
WO2006038116A3 (en) 2006-07-13
WO2006038116A2 (en) 2006-04-13
US7524860B2 (en) 2009-04-28
CA2582482A1 (en) 2006-04-13
MX2007004179A (en) 2007-06-07

Similar Documents

Publication Publication Date Title
BRPI0516819A (en) triazolopyridine derivatives and antibacterial agents
MA33782B1 (en) INSECTICIDE COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES
BR112014017968A8 (en) AMIDINE SUBSTITUTED BETA-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS
CL2011000939A1 (en) Compounds derived from cephalosporins substituted by a catechol group, with antimicrobial activity against gram-negative bacteria that produce beta-lactamase; pharmaceutical composition that includes them; use in the treatment of infectious diseases.
BRPI0717266A2 (en) OXINDOL DERIVATIVES
NO20090313L (en) Derivatives and analogs of N-ethylquinolones and N-ethyllazakinolones
UY32840A (en) FUNGICIDE COMPOUNDS BASED ON HETEROCICLES CONTAINING NITROGEN REPLACED WITH AN AROMATIC RING OF SIX MEMBERS
UY31038A1 (en) COMPOUNDS
DOP2011000176A (en) ORGANIC COMPOUNDS
ECSP099451A (en) ANTIBACTERIAL POLICE POLICYCLES OF UREA
CO6470837A2 (en) SUBSTITUTED KINAZOLINS AS FUNGICIDES
DK1954697T3 (en) Pericondensed tricyclic compounds useful as antibacterial agents
CR8986A (en) ISOXAZOLS REPLACED AS FUNGICIDES
CR11057A (en) NEW NITROGEN HETEROCICLIC COMPOUNDS, ITS PREPARATION AND ITS USE AS ANTIBACTERIAL MEDICINES
CL2011000784A1 (en) Substituted 7-h-pyrazoli [3,4-e] -diasepine-6 (5h) -one derivative compounds; preparation procedure; pharmaceutical composition, useful as antibacterial agents.
CR10344A (en) 2- (PIRIDIN) -2-IL) -PIRIMIDINAS AS FUNGICIDES
DOP2006000268A (en) ANTIBACTERIAL AGENTS
CR20110294A (en) PIPERIDINE ESPIRO PIRROLIDINONA AND PIPERIDINONA REPLACED, ITS PREPARATION AND THERAPEUTIC USE
BRPI0707117B8 (en) Mutilin derivatives, their use, and pharmaceutical composition
ECSP088922A (en) DERIVATIVES OF AMINO-TIAZOL AND ITS USES AS ANTIBACTERIAL AGENTS
ECSP055980A (en) INDEXOX OXAZOLIDINONES AND DERIVATIVES OF THE SAME
ME00582A (en) Tricyclic compound and pharmaceutical use thereof
BRPI0616111B8 (en) carboxamide derivatives, pharmaceutical composition, use thereof and combination
AR105177A2 (en) CRYSTAL FORM OF ACID 8-CIANO-1-CYCLOPROPIL-7- (1S, 6S-2,8-DIAZABICICLO- (4.3.0) NONAN-8-IL) -6-FLUOR-1,4-DIHYDRO-4-OXO -3-CHINOLINCARBOXYL
UY31143A1 (en) DERIVATIVES OF [1,10] -FENANTROLINE FOR THE TREATMENT OF NEURODEGENERATIVE OR HEMATOLOGICAL DISEASES

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.