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BRPI0411825A - inibidores de p38 quinase a base de heterociclo de 5 elementos - Google Patents

inibidores de p38 quinase a base de heterociclo de 5 elementos

Info

Publication number
BRPI0411825A
BRPI0411825A BRPI0411825-1A BRPI0411825A BRPI0411825A BR PI0411825 A BRPI0411825 A BR PI0411825A BR PI0411825 A BRPI0411825 A BR PI0411825A BR PI0411825 A BRPI0411825 A BR PI0411825A
Authority
BR
Brazil
Prior art keywords
kinase
kinase inhibitors
element heterocycle
inhibitors
disorders
Prior art date
Application number
BRPI0411825-1A
Other languages
English (en)
Inventor
Olga M Fryszman
Hengyuan Lang
Jiong Lan
Edcon Chang
Yunfeng Fang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34108816&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0411825(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0411825A publication Critical patent/BRPI0411825A/pt
Publication of BRPI0411825B1 publication Critical patent/BRPI0411825B1/pt
Publication of BRPI0411825B8 publication Critical patent/BRPI0411825B8/pt

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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

"INIBIDORES DE p38 QUINASE A BASE DE HETEROCICLO DE 5 ELEMENTOS". A presente invenção refere-se a inibidores de p38 quinase a base de heterociclo de cinco elementos. São também providos, adicionalmente, inibidores de p38 quinase a base de pirazol e imidazol, incluindo p38<244> e p38<225>. As composições farmacêuticas contendo os compostos são também providas. Os métodos de uso dos compostos e composições são também providos, incluindo método de tratamento, prevenção ou alívio de um ou mais sintomas de doenças ou distúrbios mediados por p38 quinase, incluindo, porém não limitado às doenças e distúrbios inflamatórios.
BRPI0411825A 2003-06-26 2004-06-24 inibidores de p38 quinase a base de heterociclo de 5 elementos, seus processos de preparação e seus usos, bem como composição farmacêutica BRPI0411825B8 (pt)

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US49905403P 2003-08-29 2003-08-29
US56048104P 2004-04-07 2004-04-07
PCT/US2004/020384 WO2005009973A1 (en) 2003-06-26 2004-06-24 5-membered heterocycle-based p38 kinase inhibitors

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