BRPI0417116A - usos de uma quantidade eficaz de ondansetron e composição para tratamento tópico de uma inflamação - Google Patents
usos de uma quantidade eficaz de ondansetron e composição para tratamento tópico de uma inflamaçãoInfo
- Publication number
- BRPI0417116A BRPI0417116A BRPI0417116-0A BRPI0417116A BRPI0417116A BR PI0417116 A BRPI0417116 A BR PI0417116A BR PI0417116 A BRPI0417116 A BR PI0417116A BR PI0417116 A BRPI0417116 A BR PI0417116A
- Authority
- BR
- Brazil
- Prior art keywords
- ondansetron
- composition
- inflammation
- effective amount
- topical treatment
- Prior art date
Links
- 229960005343 ondansetron Drugs 0.000 title abstract 4
- FELGMEQIXOGIFQ-CYBMUJFWSA-N (3r)-9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1h-carbazol-4-one Chemical compound CC1=NC=CN1C[C@@H]1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 FELGMEQIXOGIFQ-CYBMUJFWSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 206010061218 Inflammation Diseases 0.000 title abstract 2
- 230000004054 inflammatory process Effects 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FELGMEQIXOGIFQ-UHFFFAOYSA-N Ondansetron Chemical compound CC1=NC=CN1CC1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 FELGMEQIXOGIFQ-UHFFFAOYSA-N 0.000 abstract 1
- 241001303601 Rosacea Species 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 201000004700 rosacea Diseases 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
Abstract
"USOS DE UMA QUANTIDADE EFICAZ DE ONDANSETRON E COMPOSIçãO PARA TRATAMENTO TóPICO DE UMA INFLAMAçãO". A presente invenção trata em geral do uso do ondansetron, seus sais e base, como um princípio ativo na fabricação de composições farmacêuticas, mais particularmente composições dermatológicas, destinadas ao tratamento antiinflamatório curativo e/ou profilático pela via tópica. Mais especificamente, a presente invenção preconiza o uso do Ondansetron, seus sais e base para tratar topicamente a rosácea, um distúrbio inflamatório da pele.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52858703P | 2003-12-10 | 2003-12-10 | |
| EP04291328A EP1600158A1 (en) | 2004-05-26 | 2004-05-26 | Use of ondansetron for the treatment of inflammation, and pharmaceutical compositions thereof |
| PCT/EP2004/013841 WO2005058312A1 (en) | 2003-12-10 | 2004-12-06 | Use of ondansetron for the treatment of inflammation, and pharmaceutical compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0417116A true BRPI0417116A (pt) | 2007-03-06 |
Family
ID=34931124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0417116-0A BRPI0417116A (pt) | 2003-12-10 | 2004-12-06 | usos de uma quantidade eficaz de ondansetron e composição para tratamento tópico de uma inflamação |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070148197A1 (pt) |
| EP (2) | EP1600158A1 (pt) |
| JP (1) | JP2007513907A (pt) |
| AU (1) | AU2004298317A1 (pt) |
| BR (1) | BRPI0417116A (pt) |
| CA (1) | CA2545760A1 (pt) |
| MX (1) | MXPA06006360A (pt) |
| WO (1) | WO2005058312A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ553329A (en) * | 2004-07-22 | 2010-09-30 | Ptc Therapeutics Inc | Thienopyridines for treating hepatitis C |
| WO2007054822A2 (en) * | 2005-09-30 | 2007-05-18 | Galderma S.A. | Use of at least one avermectin or milbemycin in the treatment of ophthalmic pathologies |
| EP1993542A1 (en) * | 2006-03-01 | 2008-11-26 | Galderma Research & Development, S.N.C. | Method of treating inflammatory skin diseases using tropisetron, and pharmaceutical compositions thereof |
| FR2901702A1 (fr) * | 2006-05-31 | 2007-12-07 | Galderma Res & Dev S N C Snc | Utilisation de granisetron pour le traitement de sous-types de la rosacee, et compositions pharmaceutiques |
| FR2901703B1 (fr) * | 2006-05-31 | 2012-12-07 | Galderma Res & Dev | Utilisation de zatosetron pour le traitement de la rosacee, et compositions pharmaceutiques |
| FR2901704A1 (fr) * | 2006-05-31 | 2007-12-07 | Galderma Res & Dev S N C Snc | Utilisation de l'azasetron pour le traitement de la rosacee, et compositions pharmaceutiques |
| WO2008022484A2 (de) * | 2006-08-24 | 2008-02-28 | Novasearch Ag | Kombinationen von 5-ht3-rezeptor-antagonisten zur topischen behandlung von hauterkrankungen |
| EP2116237A1 (en) * | 2008-08-05 | 2009-11-11 | Polichem SA | Compositions for treating rosacea comprising chitosan and a dicarboxylic acid |
| CL2008002730A1 (es) * | 2008-09-12 | 2008-10-24 | Roberto Figueroa Liza Patricio | Composicion farmaceutica dermatologica, de aplicacion topica, en forma de crema, gel, unguento, solucion, emulsion que comprende 1a 99% de pentoxifilina, 0,1 a 80% de crema base y 0,1 a 75% de liposomas, util para rosacea, trastornos con fotosensibil |
| US9782425B2 (en) | 2013-07-08 | 2017-10-10 | Galderma S.A. | Treatment of papulopustular rosacea with ivermectin |
| US9233118B2 (en) | 2013-07-08 | 2016-01-12 | Galderma S.A. | Treatment of papulopustular rosacea with ivermectin |
| US12161752B2 (en) * | 2019-08-20 | 2024-12-10 | Vishwanath Padmanabhan | Compositions and methods for the treatment of anterior blepharitis and posterior blepharitis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2728165A1 (fr) * | 1994-12-19 | 1996-06-21 | Oreal | Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene |
| AU2672500A (en) * | 1999-02-18 | 2000-09-04 | Novartis Ag | Systemic use of 5-ht3 receptor antagonists against rheumatic inflammatory processes |
| DE19929197A1 (de) * | 1999-06-25 | 2000-12-28 | Novosis Pharma Ag | Transdermalsysteme zur Abgabe von 5-HT3-Rezeptor-Antagonisten und ihre Verwendung zur antiemitischen Behandlung |
| KR100393478B1 (ko) * | 2000-03-29 | 2003-08-06 | 주식회사종근당 | 자가유화 매트릭스형 경점막·경피흡수제제 |
| US7643874B2 (en) * | 2001-10-24 | 2010-01-05 | Power Paper Ltd. | Dermal patch |
-
2004
- 2004-05-26 EP EP04291328A patent/EP1600158A1/en not_active Withdrawn
- 2004-12-06 JP JP2006543452A patent/JP2007513907A/ja active Pending
- 2004-12-06 AU AU2004298317A patent/AU2004298317A1/en not_active Abandoned
- 2004-12-06 EP EP04820418A patent/EP1696908A1/en not_active Withdrawn
- 2004-12-06 BR BRPI0417116-0A patent/BRPI0417116A/pt not_active IP Right Cessation
- 2004-12-06 WO PCT/EP2004/013841 patent/WO2005058312A1/en not_active Ceased
- 2004-12-06 MX MXPA06006360A patent/MXPA06006360A/es not_active Application Discontinuation
- 2004-12-06 CA CA002545760A patent/CA2545760A1/en not_active Abandoned
-
2006
- 2006-06-12 US US11/450,390 patent/US20070148197A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20070148197A1 (en) | 2007-06-28 |
| CA2545760A1 (en) | 2005-06-30 |
| AU2004298317A2 (en) | 2005-06-30 |
| JP2007513907A (ja) | 2007-05-31 |
| WO2005058312A1 (en) | 2005-06-30 |
| AU2004298317A1 (en) | 2005-06-30 |
| EP1600158A1 (en) | 2005-11-30 |
| MXPA06006360A (es) | 2006-08-23 |
| EP1696908A1 (en) | 2006-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |