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BR9916746A - Compostos anti-inflamatórios que inibem adesão de célula - Google Patents

Compostos anti-inflamatórios que inibem adesão de célula

Info

Publication number
BR9916746A
BR9916746A BR9916746-8A BR9916746A BR9916746A BR 9916746 A BR9916746 A BR 9916746A BR 9916746 A BR9916746 A BR 9916746A BR 9916746 A BR9916746 A BR 9916746A
Authority
BR
Brazil
Prior art keywords
cell adhesion
inhibit cell
compounds
antiinflammatory compounds
formula
Prior art date
Application number
BR9916746-8A
Other languages
English (en)
Inventor
David L Arendsen
Pramila Bhatia
Steven A Boyd
Kevin R Condroski
Jennifer C Freeman
Indrani W Gunawardana
Kraig Lartey
Catherine M Mccarty
Nicholas A Mort
Meena V Patel
Michael A Staeger
Andrew O Stewart
David M Stout
Gui-Dong Zhu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/325,336 external-priority patent/US6232320B1/en
Application filed by Abbott Lab filed Critical Abbott Lab
Priority claimed from PCT/US1999/014596 external-priority patent/WO2000075145A1/en
Publication of BR9916746A publication Critical patent/BR9916746A/pt

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"COMPOSTOS ANTIINFLAMATóRIOS QUE INIBEM ADESãO DE CéLULA". Os compostos possuindo a fórmula (I) são úteis para o tratamento de inflamação. Também são reveladas composições farmacêuticas compreendendo os compostos da fórmula (I) e processos para inibir/tratar doenças inflamatórias em um mamífero.
BR9916746-8A 1999-06-03 1999-06-28 Compostos anti-inflamatórios que inibem adesão de célula BR9916746A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/325,336 US6232320B1 (en) 1998-06-04 1999-06-03 Cell adhesion-inhibiting antiinflammatory compounds
PCT/US1999/014596 WO2000075145A1 (en) 1999-06-03 1999-06-28 Cell adhesion-inhibiting antiinflammatory compounds

Publications (1)

Publication Number Publication Date
BR9916746A true BR9916746A (pt) 2005-01-11

Family

ID=56289920

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9916746-8A BR9916746A (pt) 1999-06-03 1999-06-28 Compostos anti-inflamatórios que inibem adesão de célula

Country Status (3)

Country Link
JP (1) JP2004509059A (pt)
BR (1) BR9916746A (pt)
CA (1) CA2390948A1 (pt)

Families Citing this family (33)

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KR100796965B1 (ko) * 2004-05-04 2008-01-22 에프. 호프만-라 로슈 아게 Ｉｋｋ 저해제로서의 티에노피리딘
TW200611695A (en) 2004-06-09 2006-04-16 Glaxo Group Ltd Pyrrolopyridine derivatives
AU2005270068B2 (en) * 2004-07-02 2012-04-19 Exelixis, Inc. C-Met modulators and method of use
GB0420719D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
KR20140008471A (ko) * 2004-10-21 2014-01-21 다우 아그로사이언시즈 엘엘씨 살진균 활성을 갖는 티에노-피리미딘 화합물
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KR20100065191A (ko) 2007-09-14 2010-06-15 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 １,３-이치환된 ４-(아릴-ｘ-페닐)-１ｈ-피리딘-２-온
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CN102232074B (zh) 2008-11-28 2014-12-03 奥梅-杨森制药有限公司 作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物
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CA2814998C (en) 2010-11-08 2019-10-29 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
ES2552455T3 (es) 2010-11-08 2015-11-30 Janssen Pharmaceuticals, Inc. Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
US8993591B2 (en) 2010-11-08 2015-03-31 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors
JP6218848B2 (ja) * 2012-11-20 2017-10-25 プロキナーゼ ゲゼルシャフト ミット ベシュレンクテル ハフツング プロテインキナーゼ阻害剤としてのチオエーテル誘導体
SG11201505878UA (en) * 2013-02-19 2015-09-29 Pfizer Azabenzimidazole compounds as inhibitors of pde4 isozymes for the treatment of cns and other disorders
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JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
PH12019500127B1 (en) 2014-01-21 2022-05-04 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
SMT201900545T1 (it) 2014-01-21 2019-11-13 Janssen Pharmaceutica Nv Combinazioni comprendenti modulatori allosterici positivi o agonisti ortosterici del recettore glutammatergico metabotropico sottotipo 2 e loro utilizzo
KR101551313B1 (ko) * 2014-07-28 2015-09-09 충남대학교산학협력단 신규한 인덴 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 망막 질환의 예방 또는 치료용 약학적 조성물
GB201520499D0 (en) 2015-11-20 2016-01-06 Medical Res Council Technology Compounds
CN113855670B (zh) * 2021-11-03 2023-06-09 上海市肺科医院 A205804在制备治疗脓毒症药物中的应用
CN114950492B (zh) * 2022-05-31 2023-09-08 安徽大学 一种用于光电催化杀灭细菌的1,2-二氨基蒽醌-二硫化钼复合抗菌材料
CN117682974B (zh) * 2024-02-02 2024-04-16 济南悟通生物科技有限公司 一种2-丙酰基-1-吡咯啉的制备方法

Also Published As

Publication number Publication date
JP2004509059A (ja) 2004-03-25
CA2390948A1 (en) 2000-12-14

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired