BR9915984A - Método de tratar púrpura trombocitopênica e sìndrome urêmica hemolìtica - Google Patents
Método de tratar púrpura trombocitopênica e sìndrome urêmica hemolìticaInfo
- Publication number
- BR9915984A BR9915984A BR9915984-8A BR9915984A BR9915984A BR 9915984 A BR9915984 A BR 9915984A BR 9915984 A BR9915984 A BR 9915984A BR 9915984 A BR9915984 A BR 9915984A
- Authority
- BR
- Brazil
- Prior art keywords
- thrombocytopenic purpura
- uremic syndrome
- hemolytic uremic
- provides
- treating thrombocytopenic
- Prior art date
Links
- 208000032759 Hemolytic-Uremic Syndrome Diseases 0.000 title abstract 3
- 206010043561 Thrombocytopenic purpura Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 206010062713 Haemorrhagic diathesis Diseases 0.000 abstract 1
- 101800004937 Protein C Proteins 0.000 abstract 1
- 102100036546 Salivary acidic proline-rich phosphoprotein 1/2 Human genes 0.000 abstract 1
- 101800001700 Saposin-D Proteins 0.000 abstract 1
- 201000007023 Thrombotic Thrombocytopenic Purpura Diseases 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127090 anticoagulant agent Drugs 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000031169 hemorrhagic disease Diseases 0.000 abstract 1
- 229960000856 protein c Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4866—Protein C (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- External Artificial Organs (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Patente de Invenção: <B>"MéTODO DE TRATAR PúRPURA TROMBOCITOPêNICA E SìNDROME URêMICA HEMOLìTICA"<D>. A presente invenção provê um método para tratar púrpura trombocitopênica trombótica (TTP) e síndrome urêmica hemolítica (HUS) com proteína C. A invenção reivindicada provê uma terapia necessária para um distúrbio potencialmente grave e debilitante ao mesmo tempo que evitando complicações tais como tendência a sangrar, toxicidade, e efeitos colaterais gerais de permuta plasmática ou dos agentes anticoagulantes atualmente disponíveis.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11177098P | 1998-12-10 | 1998-12-10 | |
| PCT/US1999/028433 WO2000033867A1 (en) | 1998-12-10 | 1999-12-01 | Method of treating thrombocytopenic purpura and hemolytic uremic syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9915984A true BR9915984A (pt) | 2001-09-04 |
Family
ID=22340356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9915984-8A BR9915984A (pt) | 1998-12-10 | 1999-12-01 | Método de tratar púrpura trombocitopênica e sìndrome urêmica hemolìtica |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20010003740A1 (pt) |
| EP (1) | EP1137432B1 (pt) |
| JP (1) | JP2002531519A (pt) |
| CN (1) | CN1329503A (pt) |
| AT (1) | ATE264113T1 (pt) |
| AU (1) | AU1838500A (pt) |
| BR (1) | BR9915984A (pt) |
| CA (1) | CA2351555A1 (pt) |
| DE (1) | DE69916493T2 (pt) |
| ES (1) | ES2219094T3 (pt) |
| IL (1) | IL142249A0 (pt) |
| WO (1) | WO2000033867A1 (pt) |
| ZA (1) | ZA200102730B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2002028416A1 (ja) * | 2000-09-30 | 2004-02-12 | 持田製薬株式会社 | 溶血性貧血の予防・治療剤 |
| US20100284997A1 (en) * | 2006-10-31 | 2010-11-11 | Griffin John H | Dosing regimen of activated protein c and variants having reduced anticoagulant activity |
| CN111035754A (zh) * | 2016-03-23 | 2020-04-21 | 兆科药业（合肥）有限公司 | 抗血小板溶栓素在制备治疗血栓性血小板减少性紫癜的药物中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516650A (en) * | 1985-06-27 | 1996-05-14 | Zymogenetics, Inc. | Production of activated protein C |
| CO4940438A1 (es) * | 1997-04-28 | 2000-07-24 | Lilly Co Eli | Metodos mejorados para el procesamiento de proteina c acti- vada |
-
1999
- 1999-12-01 AT AT99961896T patent/ATE264113T1/de not_active IP Right Cessation
- 1999-12-01 BR BR9915984-8A patent/BR9915984A/pt not_active Application Discontinuation
- 1999-12-01 IL IL14224999A patent/IL142249A0/xx unknown
- 1999-12-01 CN CN99814123A patent/CN1329503A/zh active Pending
- 1999-12-01 WO PCT/US1999/028433 patent/WO2000033867A1/en not_active Ceased
- 1999-12-01 CA CA002351555A patent/CA2351555A1/en not_active Abandoned
- 1999-12-01 AU AU18385/00A patent/AU1838500A/en not_active Abandoned
- 1999-12-01 ES ES99961896T patent/ES2219094T3/es not_active Expired - Lifetime
- 1999-12-01 EP EP99961896A patent/EP1137432B1/en not_active Expired - Lifetime
- 1999-12-01 DE DE69916493T patent/DE69916493T2/de not_active Expired - Fee Related
- 1999-12-01 JP JP2000586357A patent/JP2002531519A/ja not_active Withdrawn
-
2000
- 2000-12-07 US US09/731,467 patent/US20010003740A1/en not_active Abandoned
-
2001
- 2001-04-03 ZA ZA200102730A patent/ZA200102730B/en unknown
-
2003
- 2003-06-24 US US10/602,936 patent/US20040087643A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2351555A1 (en) | 2000-06-15 |
| US20010003740A1 (en) | 2001-06-14 |
| ATE264113T1 (de) | 2004-04-15 |
| EP1137432B1 (en) | 2004-04-14 |
| WO2000033867A1 (en) | 2000-06-15 |
| ZA200102730B (en) | 2002-07-03 |
| ES2219094T3 (es) | 2004-11-16 |
| DE69916493D1 (de) | 2004-05-19 |
| JP2002531519A (ja) | 2002-09-24 |
| AU1838500A (en) | 2000-06-26 |
| EP1137432A1 (en) | 2001-10-04 |
| IL142249A0 (en) | 2002-03-10 |
| DE69916493T2 (de) | 2005-03-24 |
| CN1329503A (zh) | 2002-01-02 |
| US20040087643A1 (en) | 2004-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69626660D1 (en) | 2-alkylpyrrolidine | |
| PT817627E (pt) | Inibidores da proteina cinase c | |
| DK1481682T3 (da) | Præparat som indeholder oligosaccharider og probiotika | |
| WO1999037340A3 (en) | Biological fluid treatment system | |
| DK0840606T3 (da) | Små di- og trivalente molekyler som selectininhibitorer | |
| NO984928D0 (no) | Pyrazinontrombininhibitorer | |
| DK1355889T3 (da) | Substituerede triazoldiaminderivater som kinaseinhibitorer | |
| BG101984A (en) | Botulinum toxin derivatives able to modify peripheral sensory afferent functions | |
| BR9610838A (pt) | Processo para tratar um indivìduo tendo uma condição patológica envolvendo neovascularização. | |
| AU1565300A (en) | Anti-germinating method for tubers and bulbs using eugenol and/or isoeugenol | |
| DK0766682T3 (da) | Proteinkinase-C-inhibitorer | |
| IL142220A0 (en) | Method of treating viral hemorrhagic fever | |
| WO1999036064A3 (en) | Methods of treating tardive dyskinesia and other movement disorders | |
| WO2021195470A3 (en) | Identification and use of compounds in the treatment or prevention of severe acute respiratory syndrome coronavirus 2 | |
| HK1039449A1 (zh) | 治疗多发性硬化的方法 | |
| AU1171102A (en) | Uridine therapy for patients with elevated purine levels | |
| DE69813200D1 (de) | Verbesserung der wundheilung mit cm101/gbs-toxin | |
| BR9915984A (pt) | Método de tratar púrpura trombocitopênica e sìndrome urêmica hemolìtica | |
| MY113431A (en) | Substituted benzenesulfonylureas and -thioureas, process for their preparation, their use as a medicament or diagnostic, and medicament containing them | |
| HU9700024D0 (en) | Imidazopyridin-azolidinones | |
| BR9915317A (pt) | Método de tratar trombocitopenia induzida por heparina | |
| ZA200102727B (en) | Method of treating sickle cell disease or thalassemia. | |
| AU2001276629A1 (en) | Modulation of tetraspanin function | |
| ZA981558B (en) | Inclusion complexes in aqueous solution | |
| UA42749C2 (uk) | N,n-діетил-8,8-дипропіл-2-азаспіро[4,5]декан-2-пропанамін дималеат, фармацевтична композиція, спосіб лікування |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |