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BR9914419A - Perception improvement therapy - Google Patents

Perception improvement therapy

Info

Publication number
BR9914419A
BR9914419A BR9914419-0A BR9914419A BR9914419A BR 9914419 A BR9914419 A BR 9914419A BR 9914419 A BR9914419 A BR 9914419A BR 9914419 A BR9914419 A BR 9914419A
Authority
BR
Brazil
Prior art keywords
perception
alzheimer
disease
effect
active ingredient
Prior art date
Application number
BR9914419-0A
Other languages
Portuguese (pt)
Inventor
Paul Leonce Irma De Nijs
Wim Louis Julien Prays
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BR9914419A publication Critical patent/BR9914419A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Patente de Invenção: <B>"TERAPIA PARA MELHORIA DA PERCEPçãO"<D>. A presente invenção refere-se a composições farmacêuticas, que compreendem um veículo e como um primeiro ingrediente ativo um agente antipsicótico atípico (I) e como segundo ingrediente ativo um inibidor de acetilcolinesterase (II), cada um em uma quantidade que produz um efeito terapeuticamente benéfico em pacientes que sofrem de psicose, de doença de Alzheimer ou de demências correlatas. O dito efeito terapeuticamente benéfico pode ser um efeito sinergístico sobre o funcionamento perceptivo de pacientes que sofrem da doença de Alzheimer ou de demências correlatas ou na prevenção de uma posterior deterioração da percepção nos ditos pacientes ou na redução de efeitos adversos associados a um dos ingredientes ativos através de outro dos ingredientes ativos.Invention Patent: <B> "THERAPY FOR IMPROVING PERCEPTION" <D>. The present invention relates to pharmaceutical compositions, which comprise a carrier and an atypical antipsychotic agent (I) as a first active ingredient and an acetylcholinesterase (II) inhibitor as a second active ingredient, each in an amount that produces a therapeutically effect. beneficial in patients suffering from psychosis, Alzheimer's disease or related dementias. Said therapeutically beneficial effect may be a synergistic effect on the perceptual functioning of patients suffering from Alzheimer's disease or related dementias or in preventing further deterioration of perception in said patients or in reducing adverse effects associated with one of the active ingredients. through another of the active ingredients.

BR9914419-0A 1998-10-16 1999-10-12 Perception improvement therapy BR9914419A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98203454 1998-10-16
PCT/EP1999/007804 WO2000023057A2 (en) 1998-10-16 1999-10-12 Atypical antiphsychotic in combination with acetylcholinesterase inhibitor for improving cognition

Publications (1)

Publication Number Publication Date
BR9914419A true BR9914419A (en) 2001-06-26

Family

ID=8234219

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914419-0A BR9914419A (en) 1998-10-16 1999-10-12 Perception improvement therapy

Country Status (20)

Country Link
EP (1) EP1121131A2 (en)
JP (1) JP2002527469A (en)
KR (1) KR20010072878A (en)
CN (1) CN1367697A (en)
AU (1) AU6472799A (en)
BG (1) BG105302A (en)
BR (1) BR9914419A (en)
CA (1) CA2345767A1 (en)
EE (1) EE200100136A (en)
HK (1) HK1039745A1 (en)
HR (1) HRP20010262A2 (en)
HU (1) HUP0103781A3 (en)
ID (1) ID28441A (en)
IL (1) IL142588A0 (en)
NO (1) NO20011403D0 (en)
PL (1) PL348107A1 (en)
SK (1) SK4592001A3 (en)
TR (1) TR200101082T2 (en)
WO (1) WO2000023057A2 (en)
ZA (1) ZA200103081B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0102841D0 (en) * 2001-02-05 2001-03-21 Novartis Ag Organic compounds
AU2006201188B2 (en) * 2001-02-05 2007-11-15 Novartis Ag New use of iloperidone
EP2295058B1 (en) 2001-10-30 2013-09-04 Novartis AG Depot formulations of iloperidone with a polymer
GB0216416D0 (en) 2002-07-15 2002-08-21 Novartis Ag Organic compounds
US20040192754A1 (en) * 2003-03-24 2004-09-30 Shapira Nathan Andrew Methods for treating idiopathic hyperhidrosis and associated conditions
TW200501962A (en) * 2003-04-01 2005-01-16 Novartis Ag Use of carbamazepine derivatives for the treatment of agitation in dementia patients
EP1824848A1 (en) * 2004-12-10 2007-08-29 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
US20050232990A1 (en) * 2003-12-31 2005-10-20 Garth Boehm Donepezil formulations
JP5379692B2 (en) 2006-11-09 2013-12-25 プロビオドルグ エージー 3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcers, cancer and other diseases
EP2091948B1 (en) 2006-11-30 2012-04-18 Probiodrug AG Novel inhibitors of glutaminyl cyclase
EP2117540A1 (en) 2007-03-01 2009-11-18 Probiodrug AG New use of glutaminyl cyclase inhibitors
WO2008128985A1 (en) 2007-04-18 2008-10-30 Probiodrug Ag Thiourea derivatives as glutaminyl cyclase inhibitors
MX2007008642A (en) * 2007-07-16 2009-02-25 World Trade Imp Export Wtie Ag Pharmaceutical composition comprising the combination of a benzisoxazolic derived agent and a reversible inhibiting agent of the cholinesterase enzyme prescribed for the control and treatment of psychotic disorders and dementias.
EA202092673A3 (en) 2010-02-09 2021-05-31 Дзе Джонс Хопкинс Юниверсити METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
WO2011107530A2 (en) 2010-03-03 2011-09-09 Probiodrug Ag Novel inhibitors
ES2481823T3 (en) 2010-03-10 2014-07-31 Probiodrug Ag Heterocyclic glutaminyl cyclase inhibitors (QC, EC 2.3.2.5)
EP2560953B1 (en) 2010-04-21 2016-01-06 Probiodrug AG Inhibitors of glutaminyl cyclase
ES2570167T3 (en) 2011-03-16 2016-05-17 Probiodrug Ag Benzimidazole derivatives as glutaminyl cyclase inhibitors
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
JP6433482B2 (en) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド Methods and compositions for improving cognitive function
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
BR112017025031B1 (en) 2015-05-22 2023-03-21 Agenebio, Inc LEVETIRACETAM EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS
EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
NZ242744A (en) * 1991-05-14 1997-02-24 Ernir Snorrason Use of a cholinesterase inhibitor (eg a galanthamine derivative) for treating fatigue
JP4640888B2 (en) * 1997-08-11 2011-03-02 ザ ユニヴァーシティー オブ サウス フロリダ Nicotine antagonists for neuropsychiatric disorders
DK1073432T3 (en) * 1998-04-14 2007-12-17 Gen Hospital Corp Use of D serine or D alanine for the treatment of schizophrenia

Also Published As

Publication number Publication date
JP2002527469A (en) 2002-08-27
HUP0103781A3 (en) 2003-09-29
EP1121131A2 (en) 2001-08-08
NO20011403L (en) 2001-03-20
WO2000023057A2 (en) 2000-04-27
ZA200103081B (en) 2002-07-12
NO20011403D0 (en) 2001-03-20
HUP0103781A2 (en) 2002-03-28
PL348107A1 (en) 2002-05-06
IL142588A0 (en) 2002-03-10
WO2000023057A3 (en) 2000-07-27
CN1367697A (en) 2002-09-04
HK1039745A1 (en) 2002-05-10
BG105302A (en) 2001-11-30
SK4592001A3 (en) 2001-12-03
KR20010072878A (en) 2001-07-31
TR200101082T2 (en) 2001-09-21
CA2345767A1 (en) 2000-04-27
EE200100136A (en) 2002-06-17
AU6472799A (en) 2000-05-08
HRP20010262A2 (en) 2002-06-30
ID28441A (en) 2001-05-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.