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BR9914221A - Derivados de glicopeptìdeos e composições farmacêuticas contendo os mesmos - Google Patents

Derivados de glicopeptìdeos e composições farmacêuticas contendo os mesmos

Info

Publication number
BR9914221A
BR9914221A BR9914221-0A BR9914221A BR9914221A BR 9914221 A BR9914221 A BR 9914221A BR 9914221 A BR9914221 A BR 9914221A BR 9914221 A BR9914221 A BR 9914221A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
compositions containing
same
derivatives
glycopeptide
Prior art date
Application number
BR9914221-0A
Other languages
English (en)
Other versions
BRPI9914221B8 (pt
BR9914221B1 (pt
Inventor
J Kevin Judice
Paul Ross Fatheree
Bernice M T Lam
Michael Leadbetter
Martin Sheringham Linsell
Yongqi Mu
Yan Zhu
Sean Gary Trapp
Guang Yang
Original Assignee
Advanced Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Medicine Inc filed Critical Advanced Medicine Inc
Publication of BR9914221A publication Critical patent/BR9914221A/pt
Publication of BR9914221B1 publication Critical patent/BR9914221B1/pt
Publication of BRPI9914221B8 publication Critical patent/BRPI9914221B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

<B>DERIVADOS DE GLICOPEPTìDEOS E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS<D> São revelados derivados de compostos de glicopeptídeos tendo pelo menos um substituinte de fórmula: -R^ a^-Y-R^ b^- (Z) ~ x~ onde R^ a^, R^ b^, Y, Z, e x são como definido, e composições farmacêuticas contendo tais derivados de glicopeptídeos. Os derivados de glicopeptídeos revelados são úteis como agentes antibacterianos.
BRPI9914221A 1998-12-23 1999-12-22 derivados de glicopeptídeos e composições farmacêuticas contendo os mesmos BRPI9914221B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11372898P 1998-12-23 1998-12-23
US12931399P 1999-04-14 1999-04-14
US16402499P 1999-11-04 1999-11-04
US16997899P 1999-12-10 1999-12-10
PCT/US1999/030543 WO2000039156A1 (en) 1998-12-23 1999-12-22 Glycopeptide derivatives and pharmaceutical compositions containing the same

Publications (3)

Publication Number Publication Date
BR9914221A true BR9914221A (pt) 2001-06-26
BR9914221B1 BR9914221B1 (pt) 2013-12-31
BRPI9914221B8 BRPI9914221B8 (pt) 2021-05-25

Family

ID=27493926

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9914221A BRPI9914221B8 (pt) 1998-12-23 1999-12-22 derivados de glicopeptídeos e composições farmacêuticas contendo os mesmos

Country Status (23)

Country Link
US (9) US6392012B1 (pt)
EP (1) EP1140993B1 (pt)
JP (1) JP4362017B2 (pt)
KR (1) KR100665204B1 (pt)
CN (1) CN1249081C (pt)
AT (1) ATE242783T1 (pt)
AU (1) AU768204B2 (pt)
BR (1) BRPI9914221B8 (pt)
CA (1) CA2336445C (pt)
CZ (1) CZ301184B6 (pt)
DE (1) DE69908819T2 (pt)
DK (1) DK1140993T3 (pt)
ES (1) ES2201825T3 (pt)
HK (1) HK1040721B (pt)
HU (1) HU230190B1 (pt)
IL (2) IL140093A0 (pt)
NO (1) NO326066B1 (pt)
NZ (1) NZ508594A (pt)
PL (1) PL198311B1 (pt)
PT (1) PT1140993E (pt)
SI (1) SI1140993T1 (pt)
WO (1) WO2000039156A1 (pt)
ZA (1) ZA200007222B (pt)

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WO2001083520A2 (en) * 2000-05-02 2001-11-08 Theravance,Inc Polyacid glycopeptide derivatives
DE60133198T2 (de) 2000-06-22 2009-03-12 Theravance, Inc., South San Francisco Glykopeptidderivate mit carboxysacchariden
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WO2001098329A1 (en) * 2000-06-22 2001-12-27 Theravance, Inc. Polyhydroxy glycopeptide derivatives
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TWI335332B (en) * 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
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US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
JP5192384B2 (ja) 2005-09-22 2013-05-08 メディバス エルエルシー ビス−（α−アミノ）−ジオール−ジエステル含有ポリ（エステルアミド）およびポリ（エステルウレタン）組成物および使用の方法
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
WO2007084507A2 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [ψ[CH2NH]PG4] GLYCOPEPTIDE ANTIBIOTIC ANALOGS
TW200808818A (en) 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
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GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
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CN109072271A (zh) * 2016-01-15 2018-12-21 汉堡大学 用于制备鼠李糖基化类黄酮的方法
CA3012176A1 (en) * 2016-01-28 2017-08-03 ACatechol, Inc. Photo-cleavable primer compositions and methods of use
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
AU2018273887B2 (en) * 2017-05-22 2022-09-08 Insmed Incorporated Lipo-glycopeptide cleavable derivatives and uses thereof
CN107987131B (zh) * 2017-11-16 2021-03-09 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的化合物、其制备方法和应用
CN108409837B (zh) 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
NL2023883B1 (en) * 2019-09-24 2021-04-26 Univ Leiden Antibiotic compounds
CN111620931B (zh) * 2020-06-12 2021-12-17 苏州博源医疗科技有限公司 万古霉素衍生物及其制备方法和应用
CN114213284B (zh) * 2022-01-04 2023-08-01 丽珠集团福州福兴医药有限公司 (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法

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Also Published As

Publication number Publication date
US6949681B2 (en) 2005-09-27
PT1140993E (pt) 2003-10-31
PL348451A1 (en) 2002-05-20
JP4362017B2 (ja) 2009-11-11
CN1249081C (zh) 2006-04-05
US8030445B2 (en) 2011-10-04
HU230190B1 (hu) 2015-09-28
DE69908819D1 (de) 2003-07-17
US20060241024A1 (en) 2006-10-26
NO20006323L (no) 2001-02-12
HK1040721B (en) 2003-10-17
DK1140993T3 (da) 2003-10-06
US6962970B2 (en) 2005-11-08
DE69908819T2 (de) 2004-05-06
KR20010085857A (ko) 2001-09-07
US20040204346A1 (en) 2004-10-14
CZ301184B6 (cs) 2009-12-02
CA2336445C (en) 2011-07-19
US6455669B1 (en) 2002-09-24
JP2002533472A (ja) 2002-10-08
US20050239690A1 (en) 2005-10-27
NO20006323D0 (no) 2000-12-12
US20030060598A1 (en) 2003-03-27
ATE242783T1 (de) 2003-06-15
US7723470B2 (en) 2010-05-25
WO2000039156A1 (en) 2000-07-06
HUP0400887A2 (hu) 2004-08-30
HUP0400887A3 (en) 2012-09-28
US20090215982A1 (en) 2009-08-27
EP1140993B1 (en) 2003-06-11
US6392012B1 (en) 2002-05-21
NZ508594A (en) 2003-05-30
IL140093A (en) 2006-06-11
IL140093A0 (en) 2002-02-10
PL198311B1 (pl) 2008-06-30
AU768204B2 (en) 2003-12-04
SI1140993T1 (en) 2003-12-31
CA2336445A1 (en) 2000-07-06
ES2201825T3 (es) 2004-03-16
CZ200122A3 (en) 2001-06-13
BRPI9914221B8 (pt) 2021-05-25
NO326066B1 (no) 2008-09-08
BR9914221B1 (pt) 2013-12-31
EP1140993A1 (en) 2001-10-10
US7351791B2 (en) 2008-04-01
US6444786B1 (en) 2002-09-03
US7101964B2 (en) 2006-09-05
ZA200007222B (en) 2002-03-06
KR100665204B1 (ko) 2007-01-04
AU3127300A (en) 2000-07-31
HK1040721A1 (en) 2002-06-21
CN1315961A (zh) 2001-10-03
US20080103292A1 (en) 2008-05-01

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

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