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BR9913850A - Gene ly6h - Google Patents

Gene ly6h

Info

Publication number
BR9913850A
BR9913850A BR9913850-6A BR9913850A BR9913850A BR 9913850 A BR9913850 A BR 9913850A BR 9913850 A BR9913850 A BR 9913850A BR 9913850 A BR9913850 A BR 9913850A
Authority
BR
Brazil
Prior art keywords
gene
expression vector
product
disease
ly6h gene
Prior art date
Application number
BR9913850-6A
Other languages
English (en)
Inventor
Masato Horie
Keiichi Okutomi
Yoshihiro Taniguchi
Mikio Suzuki
Yutaka Ohbuchi
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BR9913850A publication Critical patent/BR9913850A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)

Abstract

Patente de Invenção: "GENE LY6H". A presente invenção proporciona um gene específico de cérebro, de utilidade no tratamento, por exemplo, da doença de Alzheimer, que compreende uma seq³ência de nucleotídeo de acordo com a seq³ência de aminoácido mostrada na SEQ ID N°: 1 e de fragmentos da mesma; um vetor de expressão que compreende o gene; uma célula hospedeira compreendendo o vetor de expressão; um produto de expressão do gene; um anticorpo contra o produto; uma composição terapêutica e profilática para doença neurodegenerativa; e similares.
BR9913850-6A 1998-09-17 1999-09-16 Gene ly6h BR9913850A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26355098 1998-09-17
PCT/JP1999/005039 WO2000017345A1 (en) 1998-09-17 1999-09-16 Ly6h gene

Publications (1)

Publication Number Publication Date
BR9913850A true BR9913850A (pt) 2001-10-23

Family

ID=17391112

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9913850-6A BR9913850A (pt) 1998-09-17 1999-09-16 Gene ly6h

Country Status (16)

Country Link
US (4) US7432363B2 (pt)
EP (1) EP1114861B8 (pt)
JP (1) JP4403443B2 (pt)
KR (1) KR100640265B1 (pt)
CN (1) CN1240834C (pt)
AT (1) ATE346923T1 (pt)
AU (1) AU767878B2 (pt)
BR (1) BR9913850A (pt)
CA (1) CA2342770C (pt)
CY (1) CY1107552T1 (pt)
DE (1) DE69934239T8 (pt)
DK (1) DK1114861T3 (pt)
ES (1) ES2276531T3 (pt)
ID (1) ID29573A (pt)
PT (1) PT1114861E (pt)
WO (1) WO2000017345A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1114861T3 (da) * 1998-09-17 2007-03-19 Otsuka Pharma Co Ltd LY6H-gen
CA2459161A1 (en) * 2001-08-31 2003-03-13 The Rockefeller University Phosphodiesterase activity and regulation of phosphodiesterase 1b-mediated signaling in brain
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
EP1976877B2 (en) 2005-11-30 2016-10-05 AbbVie Inc. Monoclonal antibodies against amyloid beta protein and uses thereof
CA2628703C (en) 2005-11-30 2019-10-29 Abbott Laboratories Anti-a.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
EP2140021B1 (en) * 2007-02-22 2012-01-11 Genentech, Inc. Methods for detecting inflammatory bowel disease
EP2124952A2 (en) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Method for the treatment of amyloidoses
SG10201507362TA (en) 2009-08-05 2015-10-29 Intra Cellular Therapies Inc Novel Regulatory Proteins And Inhibitors
US8987419B2 (en) 2010-04-15 2015-03-24 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
MX358739B (es) 2010-08-14 2018-09-03 Abbvie Inc Star Proteinas de union a amiloide beta.
US20140286910A1 (en) * 2013-03-19 2014-09-25 Nikolai Tankovich Stem cells and methods incorporating environmental factors as a means for enhancing stem cell proliferation and plasticity
CN105385754B (zh) * 2015-10-28 2018-11-06 北京泱深生物信息技术有限公司 一种与胆管癌相关的分子标记物
WO2019006162A1 (en) * 2017-06-28 2019-01-03 Bluefin Biomedicine, Inc. ANTI-LY6H ANTIBODIES AND CONJUGATES ANTIBODY-MEDICINE
CA3070446A1 (en) 2017-07-25 2019-01-31 Immutics, Inc. Treating cancer by blocking the interaction of tim-3 and its ligand
KR102232200B1 (ko) * 2019-03-13 2021-03-25 아주대학교산학협력단 알츠하이머치매 진단 바이오마커
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
KR20230016186A (ko) 2020-05-26 2023-02-01 트루바인딩 아이엔씨. 갈렉틱-3 차단에 의한 염증성 질환의 치료 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011912A (en) * 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
JPH0348696A (ja) * 1989-07-14 1991-03-01 Toray Ind Inc ヒトリンパ球表面抗原およびそれをコードする遺伝子
AU4594696A (en) * 1995-11-13 1997-06-05 Human Genome Sciences, Inc. Human stem cell antigen 2
AU2095299A (en) * 1997-12-31 1999-07-19 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
DK1114861T3 (da) * 1998-09-17 2007-03-19 Otsuka Pharma Co Ltd LY6H-gen

Also Published As

Publication number Publication date
EP1114861B8 (en) 2008-10-01
CY1107552T1 (el) 2013-03-13
HK1038380A1 (en) 2002-03-15
EP1114861A1 (en) 2001-07-11
KR100640265B1 (ko) 2006-10-31
CA2342770A1 (en) 2000-03-30
US7582732B2 (en) 2009-09-01
ATE346923T1 (de) 2006-12-15
DK1114861T3 (da) 2007-03-19
PT1114861E (pt) 2007-01-31
KR20010085801A (ko) 2001-09-07
DE69934239D1 (de) 2007-01-11
CN1240834C (zh) 2006-02-08
ID29573A (id) 2001-09-06
US7432363B2 (en) 2008-10-07
EP1114861A4 (en) 2004-10-13
EP1114861B1 (en) 2006-11-29
AU767878B2 (en) 2003-11-27
US20090017479A1 (en) 2009-01-15
DE69934239T8 (de) 2007-12-06
US20100261880A1 (en) 2010-10-14
WO2000017345A1 (en) 2000-03-30
AU5651899A (en) 2000-04-10
US20080275218A1 (en) 2008-11-06
US20040254340A1 (en) 2004-12-16
JP4403443B2 (ja) 2010-01-27
CA2342770C (en) 2011-06-21
ES2276531T3 (es) 2007-06-16
CN1318099A (zh) 2001-10-17
DE69934239T2 (de) 2007-06-28

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (IX), 13, 15 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.