BR9913329A - Manipulação de nìveis de tocoferol em plantas transgênicas - Google Patents
Manipulação de nìveis de tocoferol em plantas transgênicasInfo
- Publication number
- BR9913329A BR9913329A BR9913329-6A BR9913329A BR9913329A BR 9913329 A BR9913329 A BR 9913329A BR 9913329 A BR9913329 A BR 9913329A BR 9913329 A BR9913329 A BR 9913329A
- Authority
- BR
- Brazil
- Prior art keywords
- methyl
- transgenic plants
- solanylplastoquinol
- methyltransferase
- tocopherol
- Prior art date
Links
- 229930003799 tocopherol Natural products 0.000 title abstract 6
- 239000011732 tocopherol Substances 0.000 title abstract 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 title abstract 4
- 229960001295 tocopherol Drugs 0.000 title abstract 4
- 235000010384 tocopherol Nutrition 0.000 title abstract 4
- 230000009261 transgenic effect Effects 0.000 title abstract 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title abstract 4
- 241000196324 Embryophyta Species 0.000 abstract 7
- 108060004795 Methyltransferase Proteins 0.000 abstract 4
- 102000016397 Methyltransferase Human genes 0.000 abstract 4
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 230000002068 genetic effect Effects 0.000 abstract 2
- 230000000243 photosynthetic effect Effects 0.000 abstract 2
- 235000019149 tocopherols Nutrition 0.000 abstract 2
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 abstract 2
- 108091026890 Coding region Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- WKFUDLTXRQQGHB-UHFFFAOYSA-N plastoquinol-1 Chemical class CC(C)=CCC1=CC(O)=C(C)C(C)=C1O WKFUDLTXRQQGHB-UHFFFAOYSA-N 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"MANIPULAçãO DE NìVEIS DE TOCOFEROL EM PLANTAS TRANSGêNICAS". é aqui descrita uma seq³ência de gene que foi identificada com codificadora de 2-metil-6-fitilplas-toquinol/2-metil-6-solanilplastoquinol-9 metiltransferase da partir de organismos fotossintéticos. A enzima 2-metil-6-fitilplastoquinol/ 2-metil-6-solanilplastoqui-nol-9-metil-transferase é uma enzima fundamental na produção de tocoferóis e plastoquinóis em plantas superiores. Acredita-se que a 2-metil-6-fitilplastoquinil/2-metil-6-solanilplastoquinol-9 metiltransferase esteja envolvida na regulação das quantidades relativas dos vários tocoferóis presentes em organismos fotossintéticos. Por meio da introdução de uma construção genética tendo uma seq³ência genética de codificação de 2-metil-6-fitilplastoquinol/2-metil-6-solanilplas-toquinol-9 metiltransferase sob o controle de um promotor de planta em uma planta, podem ser feitas plantas transgênicas tendo a expressão de 2-metil-6-fitilplastoquinol/2-metil-6-solanilplastoquinol-9 metiltransferase para efetuar alterações no perfil de tocoferol da planta. Plantas transgênicas podem ser feitas tendo níveis alterados de tocoferol em seus tecidos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9786398P | 1998-08-25 | 1998-08-25 | |
| PCT/US1999/019483 WO2000010380A1 (en) | 1998-08-25 | 1999-08-25 | Manipulation of tocopherol levels in transgenic plants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9913329A true BR9913329A (pt) | 2002-01-15 |
Family
ID=22265494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9913329-6A BR9913329A (pt) | 1998-08-25 | 1999-08-25 | Manipulação de nìveis de tocoferol em plantas transgênicas |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6448475B1 (pt) |
| EP (1) | EP1107662A4 (pt) |
| JP (1) | JP2002525038A (pt) |
| CN (1) | CN1324211A (pt) |
| AU (1) | AU775589B2 (pt) |
| BR (1) | BR9913329A (pt) |
| CA (1) | CA2340857A1 (pt) |
| IL (1) | IL141616A0 (pt) |
| MX (1) | MXPA01001989A (pt) |
| WO (1) | WO2000010380A1 (pt) |
| ZA (1) | ZA200101561B (pt) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6642434B1 (en) * | 1997-07-25 | 2003-11-04 | University Of Community College System Of Nevada | Transgenic plants with γ-tocopherol methyltransferase |
| CA2372120A1 (en) * | 1999-04-12 | 2000-10-19 | Monsanto Company | Transgenic plants containing altered levels of sterol compounds and tocopherols |
| EP1190068B1 (en) | 1999-04-15 | 2006-01-25 | Calgene LLC | Nucleic acid sequences to proteins involved in tocopherol synthesis |
| US6787683B1 (en) | 1999-05-07 | 2004-09-07 | Pioneer Hi-Bred International, Inc. | Phytyl/prenyltransferase nucleic acids, polypeptides and uses thereof |
| DE19931834A1 (de) * | 1999-07-09 | 2001-01-11 | Sungene Gmbh & Co Kgaa | Identifizierung und Überexpression einer DNA-Sequenz codierend für eine 2-Methyl-6-phytylhydrochinon-methyltransferase in Pflanzen |
| AU5354301A (en) * | 2000-04-14 | 2001-10-30 | Monsanto Technology Llp | Nucleic acid sequences to proteins involved in tocopherol synthesis |
| US6872815B1 (en) | 2000-10-14 | 2005-03-29 | Calgene Llc | Nucleic acid sequences to proteins involved in tocopherol synthesis |
| AU9052201A (en) | 2000-08-07 | 2002-02-18 | Monsanto Technology Llc | Methyl-d-erythritol phosphate pathway genes |
| DE10046462A1 (de) * | 2000-09-19 | 2002-05-29 | Sungene Gmbh & Co Kgaa | Verbesserte Verfahren zur Vitamin E Biosynthese |
| WO2002090506A2 (en) * | 2001-05-09 | 2002-11-14 | Monsanto Technology Llc | Metabolite transporters |
| DE60230608D1 (de) | 2001-05-09 | 2009-02-12 | Monsanto Technology Llc | Tyra-gene und ihre verwendung |
| EP1950305A1 (en) | 2001-05-09 | 2008-07-30 | Monsanto Technology, LLC | Tyr a genes and uses thereof |
| EP1897952A3 (en) * | 2001-08-17 | 2009-12-09 | Monsanto Technology, LLC | Methyltransferasegenes and uses thereof |
| AU2002329759A1 (en) | 2001-08-17 | 2003-03-03 | Monsanto Technology Llc | Methyltransferase genes and uses thereof |
| PT1440151E (pt) * | 2001-09-05 | 2008-03-17 | Monsanto Technology Llc | Promotor 7s alfa específico da semente para expressar genes em plantas |
| AU2002342114B2 (en) * | 2001-10-25 | 2008-07-31 | Monsanto Technology Llc | Aromatic methyltransferases and uses thereof |
| US20030144219A1 (en) | 2001-11-15 | 2003-07-31 | Phinney Stephen Dodge | Formulations and methods for treatment or amelioration of inflammatory conditions |
| BRPI0308740B1 (pt) | 2002-03-19 | 2018-11-21 | Monsanto Technology Llc | molécula de ácido nucléico codificando uma homogentisato prenil transferase (“hpt”) e método de produzir planta tendo semente com nível de tocoferol aumentado |
| EP2216405A1 (en) | 2002-05-03 | 2010-08-11 | Monsanto Technology LLC | Speed specific USP promoters for expressing genes in plants |
| AU2003245914A1 (en) * | 2002-06-07 | 2003-12-22 | Sungene Gmbh And Co. Kgaa | Transgenic expression constructs and method for increasing the vitamin e content in plant organisms |
| EP1546334A4 (en) * | 2002-08-05 | 2007-01-03 | Monsanto Technology Llc | GENES ASSOCIATED WITH TOCOPHEROL BIOSYNTHESIS AND USES THEREOF |
| US7078234B2 (en) | 2002-12-18 | 2006-07-18 | Monsanto Technology Llc | Maize embryo-specific promoter compositions and methods for use thereof |
| WO2004087878A2 (en) | 2003-03-28 | 2004-10-14 | Monsanto Technology, Llc | Novel plant promoters for use in early seed development |
| ES2233174B1 (es) * | 2003-04-10 | 2006-10-01 | Consejo Sup. Investig. Cientificas | Aceite de semilla de girasol con alto contenido en delta-tocoferol. |
| ES2232276B1 (es) * | 2003-04-10 | 2006-10-01 | Consejo Sup. Investig. Cientificas | Aceite de semilla de girasol con alto contenido en beta-tocoferol. |
| CN101128591B (zh) | 2005-02-26 | 2013-02-13 | 巴斯福植物科学有限公司 | 用于植物中种子偏好性表达的表达盒 |
| ATE552343T1 (de) | 2005-04-19 | 2012-04-15 | Basf Plant Science Gmbh | Endosperm-spezifische expression und/oder expression in keimenden embryos monokotyledoner pflanzen |
| EP1882037A2 (en) | 2005-05-10 | 2008-01-30 | BASF Plant Science GmbH | Expression cassettes for seed-preferential expression in plants |
| CN101631868B (zh) | 2007-02-16 | 2016-02-10 | 巴斯福植物科学有限公司 | 用于在单子叶植物中调节胚特异性表达的核酸序列 |
| CN101565712B (zh) * | 2008-11-27 | 2010-12-08 | 上海交通大学 | 生菜mpbq mt蛋白编码序列 |
| CA2758824A1 (en) | 2009-04-17 | 2010-10-21 | Basf Plant Science Company Gmbh | Plant promoter operable in endosperm and uses thereof |
| BR112012000448A2 (pt) | 2009-07-10 | 2015-10-06 | Basf Plant Science Gmbh | cassete de expressão para a regulação da expressão semente-específica de um polinucleotídeo de interesse, vetor, célula hospedeira, tecido de planta, órgão de planta, planta ou semente transgênicos, metodo para expressar um polinucleotídeo de interesse em uma célula hospedeira, métodos para produzir um tecido vegetal, órgão de planta, planta, ou semente transgênicos e uso do cassete de expressão |
| CA2782290A1 (en) | 2009-12-03 | 2011-06-09 | Basf Plant Science Company Gmbh | Expression cassettes for embryo-specific expression in plants |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6087563A (en) * | 1996-01-29 | 2000-07-11 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Cloned arabidopsis p-hydroxyphenyl pyruvic acid dioxygenase DNA |
-
1999
- 1999-08-25 AU AU57861/99A patent/AU775589B2/en not_active Expired - Fee Related
- 1999-08-25 US US09/382,906 patent/US6448475B1/en not_active Expired - Fee Related
- 1999-08-25 CA CA002340857A patent/CA2340857A1/en not_active Abandoned
- 1999-08-25 CN CN99812505.9A patent/CN1324211A/zh active Pending
- 1999-08-25 BR BR9913329-6A patent/BR9913329A/pt not_active IP Right Cessation
- 1999-08-25 EP EP99945207A patent/EP1107662A4/en not_active Withdrawn
- 1999-08-25 MX MXPA01001989A patent/MXPA01001989A/es unknown
- 1999-08-25 IL IL14161699A patent/IL141616A0/xx unknown
- 1999-08-25 WO PCT/US1999/019483 patent/WO2000010380A1/en not_active Ceased
- 1999-08-25 JP JP2000565715A patent/JP2002525038A/ja active Pending
-
2001
- 2001-02-26 ZA ZA200101561A patent/ZA200101561B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1107662A4 (en) | 2003-07-02 |
| CN1324211A (zh) | 2001-11-28 |
| EP1107662A1 (en) | 2001-06-20 |
| WO2000010380A1 (en) | 2000-03-02 |
| MXPA01001989A (es) | 2002-10-31 |
| JP2002525038A (ja) | 2002-08-13 |
| ZA200101561B (en) | 2001-09-17 |
| IL141616A0 (en) | 2002-03-10 |
| AU5786199A (en) | 2000-03-14 |
| CA2340857A1 (en) | 2000-03-02 |
| US6448475B1 (en) | 2002-09-10 |
| AU775589B2 (en) | 2004-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 3,5 A 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007. |