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BR9911140A - Membrana ou matriz para controlar a velocidade de permeação de farmacos - Google Patents

Membrana ou matriz para controlar a velocidade de permeação de farmacos

Info

Publication number
BR9911140A
BR9911140A BR9911140-3A BR9911140A BR9911140A BR 9911140 A BR9911140 A BR 9911140A BR 9911140 A BR9911140 A BR 9911140A BR 9911140 A BR9911140 A BR 9911140A
Authority
BR
Brazil
Prior art keywords
membrane
matrix
rate
control
elastomeric composition
Prior art date
Application number
BR9911140-3A
Other languages
English (en)
Other versions
BR9911140B1 (pt
Inventor
Harri Jukarainen
Tommi Markkula
Juha Ala-Sorvari
Matti Lehtinen
Jarkko Ruohonen
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of BR9911140A publication Critical patent/BR9911140A/pt
Publication of BR9911140B1 publication Critical patent/BR9911140B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/10—Block- or graft-copolymers containing polysiloxane sequences
    • C08L83/12—Block- or graft-copolymers containing polysiloxane sequences containing polyether sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Silicon Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Wrappers (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Materials For Medical Uses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

''MEMBRANA OU MATRIZ PARA CONTROLAR A VELOCIDADE DE PERMEAçãO DE FáRMACOS''. A invenção refere-se a uma membrana ou matriz para controlar a velocidade de permeação de um fármaco, em que a dita membrana ou matriz compreende uma composição elastomérica baseada em siloxano, que compreende pelo menos um elastómero e possivelmente um polímero não reticulado. A composição elastomérica compreende grupos polioxialquilênicos, e os grupos polioxialquilênicos estão presentes no elastómero ou no polímero como enxertos terminados com alcóxi das unidades de polissiloxano, ou como blocos, sendo que os ditos enxertos ou blocos estão ligados às unidades de polissiloxano por ligações silício-carbono, ou como uma mistura dessas formas. A invenção refere-se também a métodos para preparar a composição elastomérica a ser usada na dita membrana ou matriz.
BRPI9911140-3A 1998-06-30 1999-06-11 membrana ou matriz para controlar a velocidade de permeação de fármacos e método para preparação de um elastÈmero. BR9911140B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI981506A FI107339B (fi) 1998-06-30 1998-06-30 Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi
PCT/FI1999/000511 WO2000000550A1 (en) 1998-06-30 1999-06-11 A membrane or matrix for controlling the permeation rate of drugs

Publications (2)

Publication Number Publication Date
BR9911140A true BR9911140A (pt) 2001-03-06
BR9911140B1 BR9911140B1 (pt) 2009-08-11

Family

ID=8552104

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9911140-3A BR9911140B1 (pt) 1998-06-30 1999-06-11 membrana ou matriz para controlar a velocidade de permeação de fármacos e método para preparação de um elastÈmero.

Country Status (28)

Country Link
EP (1) EP1124902B1 (pt)
JP (1) JP2002519467A (pt)
KR (1) KR100599868B1 (pt)
CN (2) CN1176999C (pt)
AR (1) AR018952A1 (pt)
AT (1) ATE290049T1 (pt)
AU (1) AU752895B2 (pt)
BG (1) BG65148B1 (pt)
BR (1) BR9911140B1 (pt)
CA (1) CA2336149C (pt)
CO (1) CO5060523A1 (pt)
CZ (1) CZ299613B6 (pt)
DE (1) DE69923992T2 (pt)
EE (1) EE04685B1 (pt)
ES (1) ES2237120T3 (pt)
FI (1) FI107339B (pt)
HU (1) HU229159B1 (pt)
NO (1) NO327955B1 (pt)
NZ (1) NZ508275A (pt)
PE (1) PE20000935A1 (pt)
PL (1) PL193485B1 (pt)
PT (1) PT1124902E (pt)
RU (1) RU2201794C2 (pt)
SK (1) SK285325B6 (pt)
TW (1) TWI237571B (pt)
UA (1) UA71566C2 (pt)
WO (1) WO2000000550A1 (pt)
ZA (1) ZA200006986B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476079B1 (en) 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
AU2002210580A1 (en) * 2000-10-20 2002-04-29 Leiras Oy Drug delivery system
EP1438942A1 (en) 2003-01-17 2004-07-21 Schering Oy An otorhinological drug delivery device
EP1799754B1 (en) * 2004-08-25 2008-03-19 Union Carbide Chemicals & Plastics Technology Corporation Polymeric film
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
CA2675585C (en) 2007-03-12 2015-10-06 Bayer Schering Pharma Oy Use of tocopherol as a co-catalyst for ring opening polymerization of cyclic siloxanes
EP2140860A1 (en) 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
FI20080523A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
US11992431B2 (en) 2008-09-17 2024-05-28 Bayer Oy Inserter
FI20080524A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
HRP20130510T4 (hr) 2008-09-17 2016-10-21 Bayer Oy Aplikator za umetanje
FI122579B (fi) 2010-10-29 2012-03-30 Bayer Oy Insertteri
CN102008909B (zh) * 2010-12-13 2012-10-10 大连欧科膜技术工程有限公司 一种气体分离复合膜的制备方法
CN102068914B (zh) * 2010-12-13 2012-10-10 大连欧科膜技术工程有限公司 一种气体分离复合膜的制备方法
TW201350122A (zh) 2012-04-23 2013-12-16 Bayer Pharma AG １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途
KR20150005548A (ko) 2012-04-23 2015-01-14 바이엘 파마 악티엔게젤샤프트 월경과다증의 치료에서의 18-메틸-15β,16β-메틸렌-19-노르-20-스피록스-4-엔-3-온 시스템의 용도, 및 자궁 출혈 장애의 치료를 위한 18-메틸-15β,16β-메틸렌-19-노르-20-스피록스-4-엔-3-온을 함유하는 자궁내 시스템
TN2016000134A1 (en) * 2013-10-18 2017-10-06 Bayer Oy Intrauterine delivery system.
CA2985717A1 (en) 2015-05-13 2016-11-17 Bayer Oy A long acting drug delivery device and its use in contraception
WO2018202574A1 (en) 2017-05-04 2018-11-08 Bayer Oy Intravaginal drug delivery system, method for manufacturing such system and its use in gynecological therapies and contraception
CA3085959A1 (en) 2017-12-22 2019-06-27 Alyra Biotech Pty Ltd Treatment of pain and/or pain related symptoms associated with dysmenorrhea
ES2834450T3 (es) * 2018-03-05 2021-06-17 Evonik Operations Gmbh Copolímeros en bloques de poliéter-siloxano reticulados, así como su empleo para la producción de espumas de poliuretano
WO2020237325A1 (en) 2019-05-31 2020-12-03 Alyra Biotech Pty Ltd Methods, compositions and devices for treating neuroinflammatory conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889108A (en) * 1997-06-02 1999-03-30 Dow Corning Corporation Thickening solvents with elastomeric silicone polyethers

Also Published As

Publication number Publication date
RU2201794C2 (ru) 2003-04-10
NZ508275A (en) 2002-09-27
CA2336149C (en) 2007-01-02
CN1308653A (zh) 2001-08-15
CN1269909C (zh) 2006-08-16
UA71566C2 (uk) 2004-12-15
CZ20004749A3 (cs) 2001-10-17
HU229159B1 (hu) 2013-09-30
DE69923992T2 (de) 2006-04-13
PL193485B1 (pl) 2007-02-28
PT1124902E (pt) 2005-07-29
CZ299613B6 (cs) 2008-09-17
NO20006581L (no) 2000-12-29
NO20006581D0 (no) 2000-12-21
JP2002519467A (ja) 2002-07-02
AU752895B2 (en) 2002-10-03
AR018952A1 (es) 2001-12-12
FI981506L (fi) 1999-12-31
SK18942000A3 (sk) 2001-07-10
EE200000788A (et) 2002-04-15
HUP0102600A3 (en) 2004-04-28
CO5060523A1 (es) 2001-07-30
BR9911140B1 (pt) 2009-08-11
PE20000935A1 (es) 2000-09-18
CA2336149A1 (en) 2000-01-06
BG65148B1 (bg) 2007-04-30
CN1488678A (zh) 2004-04-14
SK285325B6 (sk) 2006-11-03
DE69923992D1 (de) 2005-04-07
AU4783999A (en) 2000-01-17
ES2237120T3 (es) 2005-07-16
WO2000000550A1 (en) 2000-01-06
BG105081A (en) 2001-09-28
CN1176999C (zh) 2004-11-24
PL345103A1 (en) 2001-12-03
EE04685B1 (et) 2006-08-15
ZA200006986B (en) 2001-05-23
ATE290049T1 (de) 2005-03-15
FI107339B (fi) 2001-07-13
HUP0102600A2 (hu) 2001-11-28
TWI237571B (en) 2005-08-11
NO327955B1 (no) 2009-10-26
FI981506A0 (fi) 1998-06-30
KR100599868B1 (ko) 2006-07-12
KR20010053346A (ko) 2001-06-25
EP1124902A1 (en) 2001-08-22
EP1124902B1 (en) 2005-03-02
HK1038939A1 (en) 2002-04-04

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 22/09/2009, OBSERVADAS AS CONDICOES LEGAIS.

B25D Requested change of name of applicant approved

Owner name: SCHERING OY (FI)

Free format text: ALTERADO DE: LEIRAS OY

B25D Requested change of name of applicant approved

Owner name: BAYER SCHERING PHARMA OY (FI)

Free format text: ALTERADO DE: SCHERING OY

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 15A ANUIDADE.

B24D Patent annual fee: restoration after fee payment
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 17A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.