BR9910639A - Drogas anti-angiogênicas compreendendo peptìdeo - Google Patents
Drogas anti-angiogênicas compreendendo peptìdeoInfo
- Publication number
- BR9910639A BR9910639A BR9910639-6A BR9910639A BR9910639A BR 9910639 A BR9910639 A BR 9910639A BR 9910639 A BR9910639 A BR 9910639A BR 9910639 A BR9910639 A BR 9910639A
- Authority
- BR
- Brazil
- Prior art keywords
- peptide
- angiogenic drugs
- acyl
- angiogenic
- drugs
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 239000004037 angiogenesis inhibitor Substances 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Peptides Or Proteins (AREA)
Abstract
"DROGAS ANTI-ANGIOGêNICAS COMPREENDENDO PEPTìDEO". Peptídeos tendo a fórmula: A~ 0~-A~ 1~-A~ 2~-A~ 3~-A~ 4~-A~ 5~-A~ 6~-A~ 7~A~ 8~-A~ 9~-A~ 10~ em que A~ 0~ é selecionado dentre hidrogênio ou um grupamento acila; A~ 10~ é um grupamento hidroxila ou uma amino ácido amida; e A~ 1~, A~ 2~, A~ 3~, A~ 4~, A~ 5~, A~ 6~, A~ 7~, A~ 8~, A~ 9~ são resíduos amino acila conforme definido no presente documento.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8374598A | 1998-05-22 | 1998-05-22 | |
| US25057499A | 1999-02-16 | 1999-02-16 | |
| US27746699A | 1999-03-26 | 1999-03-26 | |
| PCT/US1999/011448 WO1999061476A1 (en) | 1998-05-22 | 1999-05-21 | Peptide antiangiogenic drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9910639A true BR9910639A (pt) | 2002-01-15 |
Family
ID=27374598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9910639-6A BR9910639A (pt) | 1998-05-22 | 1999-05-21 | Drogas anti-angiogênicas compreendendo peptìdeo |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1078002B1 (pt) |
| JP (3) | JP3753612B2 (pt) |
| KR (1) | KR100447696B1 (pt) |
| CN (1) | CN1311796A (pt) |
| AR (1) | AR018371A1 (pt) |
| AT (1) | ATE396204T1 (pt) |
| AU (1) | AU764277B2 (pt) |
| BG (1) | BG65065B1 (pt) |
| BR (1) | BR9910639A (pt) |
| CA (1) | CA2329250C (pt) |
| CO (1) | CO5080726A1 (pt) |
| CY (1) | CY1109118T1 (pt) |
| CZ (1) | CZ299639B6 (pt) |
| DE (1) | DE69938782D1 (pt) |
| ES (1) | ES2307337T3 (pt) |
| HU (1) | HUP0102579A3 (pt) |
| NO (1) | NO326871B1 (pt) |
| NZ (1) | NZ507912A (pt) |
| PL (1) | PL200471B1 (pt) |
| PT (1) | PT1078002E (pt) |
| SI (1) | SI1078002T1 (pt) |
| SK (1) | SK286554B6 (pt) |
| TR (1) | TR200003442T2 (pt) |
| TW (1) | TWI247748B (pt) |
| WO (1) | WO1999061476A1 (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6774211B1 (en) | 1998-05-22 | 2004-08-10 | Abbott Laboratories | Peptide antiangiogenic drugs |
| JP4439120B2 (ja) | 1998-10-16 | 2010-03-24 | 大塚製薬株式会社 | 新生血管特異的ペプチド |
| DK2319928T3 (da) | 1998-10-23 | 2013-06-24 | Kirin Amgen Inc | Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet |
| US7488590B2 (en) | 1998-10-23 | 2009-02-10 | Amgen Inc. | Modified peptides as therapeutic agents |
| US20020183242A1 (en) * | 2001-04-11 | 2002-12-05 | Jack Henkin | Peptide antiangiogenic drugs |
| US20030050246A1 (en) * | 2001-07-26 | 2003-03-13 | Fortuna Haviv | Peptides having antiangiogenic activity |
| US7001984B2 (en) | 2001-10-31 | 2006-02-21 | Abbott Laboratories | Di-, tri-, and tetra-peptides having antiangiogenic activity |
| US20030119746A1 (en) * | 2001-10-31 | 2003-06-26 | Fortuna Haviv | Hepta-and octapeptides having antiangiogenic activity |
| US7067490B2 (en) | 2001-10-31 | 2006-06-27 | Abbott Laboratories | Hepta-, Octa-and nonapeptides having antiangiogenic activity |
| US7169888B2 (en) | 2001-10-31 | 2007-01-30 | Abbott Laboratories | Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity |
| US20030105025A1 (en) * | 2001-10-31 | 2003-06-05 | Fortuna Haviv | Tri-and tetrapeptides having antiangiogenic activity |
| US20030125259A1 (en) | 2001-10-31 | 2003-07-03 | Fortuna Haviv | Octa- and nonapeptides having antiangiogenic activity |
| IL161527A0 (en) * | 2001-10-31 | 2004-09-27 | Abbott Lab | Hepta-, octa-and nonapeptides having antiangiogenic activity |
| US7122625B2 (en) | 2001-10-31 | 2006-10-17 | Abbott Laboratories | Hexa-, hepta-, and octapeptides having antiangiogenic activity |
| US20030125260A1 (en) * | 2001-10-31 | 2003-07-03 | Fortuna Haviv | Tetra-and pentapeptides having antiangiogenic activity |
| US7037897B2 (en) | 2001-10-31 | 2006-05-02 | Abbott Laboratories | TRI-, TETRA-, and penta-peptides having antiangiogenic activity |
| UY27523A1 (es) * | 2001-10-31 | 2003-05-30 | Abbott Lab | Tetra-, penta-, hexa-y heptapéptidos con actividad antiangiogénica |
| US7629318B2 (en) | 2002-03-22 | 2009-12-08 | Gpc Biotech Ag | Immunosuppressant compounds, methods and uses related thereto |
| US20030228365A1 (en) * | 2002-06-07 | 2003-12-11 | Fortuna Haviv | Pharmaceutical formulation |
| US7432245B2 (en) | 2002-06-07 | 2008-10-07 | Abbott Laboratories Inc. | Pharmaceutical formulation comprising a peptide angiogenesis inhibitor |
| CN101103045B (zh) | 2004-09-24 | 2015-11-25 | 安姆根有限公司 | 修饰的Fc分子 |
| EP1853294A4 (en) | 2005-03-03 | 2010-01-27 | Covx Technologies Ireland Ltd | ANTIANGIOGENIC COMPOUNDS |
| US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
| JP2007255910A (ja) * | 2006-03-20 | 2007-10-04 | Hokkaido Univ | Ｎｍｒシグナルの帰属方法 |
| JO3324B1 (ar) | 2006-04-21 | 2019-03-13 | Amgen Inc | مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية |
| WO2008003013A2 (en) * | 2006-06-29 | 2008-01-03 | Abbott Laboratories | Antitumorigenic drug combination comprising an hdac inhibitor and a tsp-1 peptidomimetic |
| CN104004057B (zh) * | 2013-02-25 | 2016-08-24 | 上海市第一人民医院 | 一类抑制新生血管的小肽及其应用 |
| CN107778355B (zh) * | 2016-08-25 | 2021-04-20 | 成都圣诺生物制药有限公司 | 一种合成西曲瑞克的方法 |
| JP2025001049A (ja) * | 2021-09-01 | 2025-01-08 | 積水メディカル株式会社 | アルギニン誘導体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200397A (en) * | 1990-02-22 | 1993-04-06 | W. R. Grace & Co.-Conn. | Use of peptide analogs of thrombospondin for the inhibition of angiogenic activity |
| WO1993016716A1 (en) * | 1992-02-24 | 1993-09-02 | Northwestern University | Method and composition for inhibiting angiogenesis |
| HU224827B1 (hu) * | 1996-05-03 | 2006-02-28 | Abbott Lab | Új antiangiogén peptidek, azokat kódoló polinukleotidok, és eljárások angiogenezis gátlására |
| EP0918795B1 (en) * | 1997-03-17 | 2004-10-27 | Abbott Laboratories | Antiangiogenic drug to treat cancer, arthritis and retinopathy |
-
1999
- 1999-05-21 AR ARP990102445A patent/AR018371A1/es active IP Right Grant
- 1999-05-21 CN CN99809104A patent/CN1311796A/zh active Pending
- 1999-05-21 NZ NZ507912A patent/NZ507912A/xx not_active IP Right Cessation
- 1999-05-21 PL PL344415A patent/PL200471B1/pl not_active IP Right Cessation
- 1999-05-21 CA CA2329250A patent/CA2329250C/en not_active Expired - Fee Related
- 1999-05-21 BR BR9910639-6A patent/BR9910639A/pt active Search and Examination
- 1999-05-21 PT PT99927091T patent/PT1078002E/pt unknown
- 1999-05-21 SI SI9931014T patent/SI1078002T1/sl unknown
- 1999-05-21 WO PCT/US1999/011448 patent/WO1999061476A1/en not_active Ceased
- 1999-05-21 TR TR2000/03442T patent/TR200003442T2/xx unknown
- 1999-05-21 EP EP99927091A patent/EP1078002B1/en not_active Expired - Lifetime
- 1999-05-21 JP JP2000550879A patent/JP3753612B2/ja not_active Expired - Fee Related
- 1999-05-21 AT AT99927091T patent/ATE396204T1/de active
- 1999-05-21 DE DE69938782T patent/DE69938782D1/de not_active Expired - Lifetime
- 1999-05-21 TW TW088108392A patent/TWI247748B/zh not_active IP Right Cessation
- 1999-05-21 ES ES99927091T patent/ES2307337T3/es not_active Expired - Lifetime
- 1999-05-21 HU HU0102579A patent/HUP0102579A3/hu unknown
- 1999-05-21 KR KR10-2000-7013153A patent/KR100447696B1/ko not_active Expired - Fee Related
- 1999-05-21 CO CO99031377A patent/CO5080726A1/es unknown
- 1999-05-21 AU AU44075/99A patent/AU764277B2/en not_active Ceased
- 1999-05-21 SK SK1763-2000A patent/SK286554B6/sk not_active IP Right Cessation
- 1999-05-21 CZ CZ20004327A patent/CZ299639B6/cs not_active IP Right Cessation
-
2000
- 2000-11-21 NO NO20005890A patent/NO326871B1/no not_active IP Right Cessation
- 2000-12-18 BG BG105064A patent/BG65065B1/bg unknown
-
2005
- 2005-05-02 JP JP2005134080A patent/JP3795906B2/ja not_active Expired - Fee Related
-
2006
- 2006-03-10 JP JP2006065255A patent/JP2006232840A/ja active Pending
-
2008
- 2008-07-29 CY CY20081100792T patent/CY1109118T1/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: ABBVIE INC. (US) |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 16A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2309 DE 07/04/2015. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |