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BR9910399A - Novos intermediários e processos para a preparação de derivados de ácido octanóico opticamente ativo - Google Patents

Novos intermediários e processos para a preparação de derivados de ácido octanóico opticamente ativo

Info

Publication number
BR9910399A
BR9910399A BR9910399-0A BR9910399A BR9910399A BR 9910399 A BR9910399 A BR 9910399A BR 9910399 A BR9910399 A BR 9910399A BR 9910399 A BR9910399 A BR 9910399A
Authority
BR
Brazil
Prior art keywords
processes
octanoic acid
preparation
optically active
acid derivatives
Prior art date
Application number
BR9910399-0A
Other languages
English (en)
Inventor
Hisashi Yamamoto
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of BR9910399A publication Critical patent/BR9910399A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

"NOVOS INTERMEDIáRIOS E PROCESSOS PARA A PREPARAçãO DE DERIVADOS DE áCIDO OCTANóICO OPTICAMENTE ATIVO" Novos intermediários, isto é, N-(2S-(2-propenil)octanoil - (1S) - (-)-2,10-canforsultam, N-(2S-(2-propinil) octanoil)-(1S)-(-)-2,10-canforsultam e N-(2R-(2-propil)octanoil)-(1S)-(-)-2,10-canforsultam; processos para preparação dos intermediários; e processos para preparação de ácido 2S-(2-propenil)octanóico, ácido 2S(2-propinil)octanóico e ácido 2R-propiloctanóico por uso dos mesmos. O ácido 2R-propiloctanóico opticamente ativo equivalente ou superior, em pureza óptica, ao preparado pelo processo da técnica anterior pode ser eficazmente preparado em etapas de reação mais curtas.
BR9910399-0A 1998-05-12 1999-05-11 Novos intermediários e processos para a preparação de derivados de ácido octanóico opticamente ativo BR9910399A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12890198 1998-05-12
PCT/JP1999/002427 WO1999058513A1 (en) 1998-05-12 1999-05-11 Novel intermediates and processes for the preparation of optically active octanoic acid derivatives

Publications (1)

Publication Number Publication Date
BR9910399A true BR9910399A (pt) 2001-01-30

Family

ID=14996168

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9910399-0A BR9910399A (pt) 1998-05-12 1999-05-11 Novos intermediários e processos para a preparação de derivados de ácido octanóico opticamente ativo

Country Status (20)

Country Link
US (2) US6333415B1 (pt)
EP (1) EP1078921B1 (pt)
JP (1) JP4147516B2 (pt)
KR (1) KR20010043514A (pt)
CN (1) CN1144796C (pt)
AT (1) ATE235475T1 (pt)
AU (1) AU748360B2 (pt)
BR (1) BR9910399A (pt)
CA (1) CA2331548A1 (pt)
DE (1) DE69906275T2 (pt)
DK (1) DK1078921T3 (pt)
ES (1) ES2195564T3 (pt)
HU (1) HUP0102401A3 (pt)
NO (1) NO20005660L (pt)
NZ (1) NZ508100A (pt)
PT (1) PT1078921E (pt)
TR (1) TR200100109T2 (pt)
TW (1) TW509672B (pt)
WO (1) WO1999058513A1 (pt)
ZA (1) ZA200006439B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI268921B (en) * 1999-02-18 2006-12-21 Ono Pharmaceutical Co A process for preparing (2R)-2-propyloctanoic acid
DE10002945A1 (de) * 2000-01-13 2001-07-26 Heinz Nau Verfahren zur Herstellung von enantiomerenreinen Analoga der Valproinsäure
US6441187B1 (en) * 2000-08-23 2002-08-27 Sumika Fine Chemicals Co., Ltd. Method for producing camphorsultam
JP2005298334A (ja) * 2001-12-19 2005-10-27 Ono Pharmaceut Co Ltd 新規な中間体化合物およびそれを用いる化合物の製造方法
EP1650187A4 (en) * 2003-04-18 2008-02-20 Kaneka Corp OPTSCH AKTIVES 2-ALLYLCARBONSÄUREDERIVATIV AND METHOD FOR THE PRODUCTION THEREOF
JP4742868B2 (ja) * 2003-06-10 2011-08-10 小野薬品工業株式会社 （２ｒ）−２−プロピルオクタン酸の製造方法、その中間体
US7820715B2 (en) * 2004-04-28 2010-10-26 Ono Pharmaceutical Co., Ltd. Crystal comprising (2R)-2-propyloctanoic acid and amine
JPWO2006075596A1 (ja) * 2005-01-13 2008-06-12 株式会社クラレ ２−アリルカルボン酸化合物の製造方法
JPWO2006098292A1 (ja) 2005-03-15 2008-08-21 小野薬品工業株式会社 眼疾患治療剤
WO2007000970A1 (ja) 2005-06-27 2007-01-04 Ono Pharmaceutical Co., Ltd. 疼痛治療剤
AU2006305309A1 (en) 2005-10-18 2007-04-26 Ono Pharmaceutical Co., Ltd. Pharmaceutical for protection of motor nerve in patient with amyotrophic lateral sclerosis
EP1974727A4 (en) 2005-12-22 2009-12-09 Ono Pharmaceutical Co THERAPEUTIC AGENT AGAINST ACUTE CEREBRALINE INFARC
US20090118542A1 (en) * 2006-02-16 2009-05-07 Shigeya Yamazaki Process for Production of Optically Active Carboxlic Acid Compound
WO2008006394A1 (en) * 2006-07-14 2008-01-17 F.I.S. Fabbrica Italiana Sintetici S.P.A Process for the preparation of optically active (4e)-5- halo-2-alkylpent-4-enoic acids and their ester derivatives
CN102417445B (zh) * 2011-11-05 2013-11-13 中国科学院山西煤炭化学研究所 一种由马来酸合成丁二酸的方法
CN102675166B (zh) * 2012-05-11 2014-03-26 山东齐都药业有限公司 用于制备2-丙基庚酸的新中间体、其制备方法及2-丙基庚酸的制备方法
US9309259B2 (en) * 2013-03-08 2016-04-12 Scinopharm Taiwan, Ltd. Process for ixabepilone, and intermediates thereof
WO2018214089A1 (zh) * 2017-05-25 2018-11-29 沈阳张明化工有限公司 2-丙基庚酸的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0632008T3 (da) 1993-06-01 1998-09-23 Ono Pharmaceutical Co Pentansyrederivater
JP3032447B2 (ja) * 1995-04-24 2000-04-17 小野薬品工業株式会社 光学活性な２−プロピルオクタン酸の製造方法
JP3084345B2 (ja) 1995-04-26 2000-09-04 小野薬品工業株式会社 光学活性な２−プロピルオクタン酸の製造方法

Also Published As

Publication number Publication date
NO20005660L (no) 2001-01-11
KR20010043514A (ko) 2001-05-25
EP1078921A1 (en) 2001-02-28
HUP0102401A2 (hu) 2001-11-28
AU3630399A (en) 1999-11-29
CA2331548A1 (en) 1999-11-18
WO1999058513A1 (en) 1999-11-18
DK1078921T3 (da) 2003-07-14
ATE235475T1 (de) 2003-04-15
TW509672B (en) 2002-11-11
HUP0102401A3 (en) 2002-01-28
TR200100109T2 (tr) 2001-06-21
DE69906275T2 (de) 2003-11-27
AU748360B2 (en) 2002-06-06
CN1309652A (zh) 2001-08-22
NO20005660D0 (no) 2000-11-09
PT1078921E (pt) 2003-06-30
CN1144796C (zh) 2004-04-07
EP1078921A4 (en) 2001-06-27
ES2195564T3 (es) 2003-12-01
NZ508100A (en) 2002-10-25
ZA200006439B (en) 2002-02-08
JP4147516B2 (ja) 2008-09-10
EP1078921B1 (en) 2003-03-26
US20020028947A1 (en) 2002-03-07
US6333415B1 (en) 2001-12-25
DE69906275D1 (de) 2003-04-30
US6392073B1 (en) 2002-05-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007.