BR9909342A - Vacinas adn adjuvadas - Google Patents
Vacinas adn adjuvadasInfo
- Publication number
- BR9909342A BR9909342A BR9909342-1A BR9909342A BR9909342A BR 9909342 A BR9909342 A BR 9909342A BR 9909342 A BR9909342 A BR 9909342A BR 9909342 A BR9909342 A BR 9909342A
- Authority
- BR
- Brazil
- Prior art keywords
- dna vaccines
- dna
- auxiliary compound
- adjuvant
- adjuvant dna
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 239000002671 adjuvant Substances 0.000 title 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 108010041986 DNA Vaccines Proteins 0.000 abstract 1
- 229940021995 DNA vaccine Drugs 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 229960001631 carbomer Drugs 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 125000005395 methacrylic acid group Chemical group 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Patente de Invenção: <B>"VACINAS ADN ADJUVADAS"<D>. A vacina ADN compreende um ADN desprotegido, incorporando e expressando in vivo uma seq³ência nucleotídica, codificando para um polipeptídeo antigênico, de preferência um gene de um agente patogênico, e pelo menos um composto auxiliar escolhido dentre os polímeros acrílico ou metacrílico e os copolímeros de anidrido maléico e de derivado alcenila. O composto auxiliar é, de preferência, um carbómero ou um EMA(r).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9804409A FR2776928B1 (fr) | 1998-04-03 | 1998-04-03 | Vaccins adn adjuves |
| PCT/FR1999/000666 WO1999051269A1 (fr) | 1998-04-03 | 1999-03-22 | Vaccins adn adjuves |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9909342A true BR9909342A (pt) | 2000-12-12 |
Family
ID=9525029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9909342-1A BR9909342A (pt) | 1998-04-03 | 1999-03-22 | Vacinas adn adjuvadas |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7163926B1 (pt) |
| EP (1) | EP1066055B1 (pt) |
| JP (1) | JP2002510651A (pt) |
| AR (1) | AR037062A1 (pt) |
| AT (1) | ATE353670T1 (pt) |
| AU (1) | AU744964B2 (pt) |
| BR (1) | BR9909342A (pt) |
| CA (1) | CA2327389C (pt) |
| CY (1) | CY1108013T1 (pt) |
| DE (1) | DE69935136T2 (pt) |
| DK (1) | DK1066055T3 (pt) |
| ES (1) | ES2283105T3 (pt) |
| FR (1) | FR2776928B1 (pt) |
| PL (1) | PL194348B1 (pt) |
| PT (1) | PT1066055E (pt) |
| WO (1) | WO1999051269A1 (pt) |
| ZA (1) | ZA992478B (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6551598B2 (en) | 2000-01-21 | 2003-04-22 | Merial | Vaccination against canine herpesvirosis and vaccines therefor |
| FR2804026B1 (fr) * | 2000-01-21 | 2004-06-11 | Merial Sas | Vaccination contre l'herpesvirose canine et vaccins |
| CA2470322A1 (en) * | 2001-12-14 | 2003-06-26 | Genetronics, Inc. | Methods for particle-assisted polynucleotide immunization using a pulsed electric field |
| US11865172B2 (en) | 2005-04-21 | 2024-01-09 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
| US7959929B2 (en) | 2005-04-21 | 2011-06-14 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
| US7682619B2 (en) | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
| UA100370C2 (uk) | 2006-12-11 | 2012-12-25 | Мериал Лимитед | Спосіб вакцинації птахів проти salmonella |
| CL2008001806A1 (es) * | 2007-06-20 | 2008-09-05 | Wyeth Corp | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
| GB0805356D0 (en) * | 2008-03-25 | 2008-04-30 | Isis Innovation | Vaccine adjuvant composition |
| US8603808B2 (en) | 2008-05-08 | 2013-12-10 | Merial Limited | Leishmania vaccine using sand fly salivary immunogen |
| KR101719005B1 (ko) * | 2008-10-24 | 2017-03-22 | 메리얼 인코포레이티드 | 아프리카 마역 바이러스에 대한 백신 |
| BR112014001287B1 (pt) | 2011-07-20 | 2020-12-08 | Centre National De La Recherche Scientifique | vacina recombinante do vírus da leucemia felina contendo gene otimizado do envelope do vírus da leucemia felina |
| WO2013106558A1 (en) | 2012-01-10 | 2013-07-18 | Merial Limited | Lipid based adjuvants for dna - plasmid vaccines |
| CA2867893C (en) | 2012-03-20 | 2022-09-20 | Merial Limited | Recombinant equine herpesvirus-1 vaccine containing mutated glycoprotein c and uses thereof |
| AU2013308627B2 (en) | 2012-08-30 | 2016-10-27 | Boehringer Ingelheim Animal Health USA Inc. | Expression of chimeric KSAC protein and method of producing soluble proteins by high pressure |
| WO2016210097A1 (en) * | 2015-06-23 | 2016-12-29 | The Trustees Of Columbia University In The City Of New York | Novel equine parvovirus and uses thereof |
| MX395520B (es) | 2016-06-17 | 2025-03-26 | Boehringer Ingelheim Animal Health Usa Inc | Formulaciones inmunogenicas novedosas que comprenden adyuvantes de polimero de acido poliacrilico lineal o ramificado. |
| CN115836042A (zh) * | 2020-07-07 | 2023-03-21 | 阿米瑞斯公司 | 疫苗佐剂及其合成和使用方法 |
| CN114272368A (zh) * | 2021-12-16 | 2022-04-05 | 成都博宠生物科技有限公司 | 一种猪瘟和猪伪狂犬二联疫苗及其制备方法和应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3920811A (en) * | 1972-12-22 | 1975-11-18 | Cutter Lab | Adjuvant compositions |
| CA1267087A (en) * | 1985-02-14 | 1990-03-27 | Nicolaas Visser | Synthetic immunogen |
| ES2052685T3 (es) * | 1987-03-17 | 1994-07-16 | Akzo Nv | Metodo para producir un adyuvante libre. |
| US6004563A (en) * | 1990-11-07 | 1999-12-21 | American Home Products Corporation | Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same |
| EP0532833A1 (en) * | 1991-05-28 | 1993-03-24 | Miles Inc. | Vaccine for equine rhinopneumonitis |
| US5922327A (en) * | 1992-06-01 | 1999-07-13 | The University Of Melbourne | Equine herpes virus glycoproteins |
| AU5543294A (en) * | 1993-10-29 | 1995-05-22 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
| BE1008977A5 (fr) * | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
| US6300118B1 (en) * | 1995-06-07 | 2001-10-09 | American Home Products Corporation | Plasmids comprising a genetically altered feline immunodeficiency virus genome |
| US5820869A (en) * | 1995-06-07 | 1998-10-13 | American Home Products Corporation | Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection |
| FR2751226B1 (fr) * | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
| GB9623051D0 (en) * | 1996-11-06 | 1997-01-08 | Schacht Etienne H | Delivery of DNA to target cells in biological systems |
| US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| EP0991767A1 (en) * | 1997-06-11 | 2000-04-12 | Institut Pasteur | Attenuated recombinant mycobacteria useful as immunogens or as vaccine components |
| AU8392898A (en) * | 1997-07-14 | 1999-02-10 | Powerject Vaccines, Inc. | Method of dna vaccination using dna encoding antigen and encoding il6 |
| GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| US6444799B1 (en) * | 1997-12-31 | 2002-09-03 | Csl Limited | P. gingivalis polynucleotides and uses thereof |
-
1998
- 1998-04-03 FR FR9804409A patent/FR2776928B1/fr not_active Expired - Lifetime
-
1999
- 1999-03-22 EP EP99909069A patent/EP1066055B1/fr not_active Expired - Lifetime
- 1999-03-22 CA CA2327389A patent/CA2327389C/en not_active Expired - Lifetime
- 1999-03-22 JP JP2000542039A patent/JP2002510651A/ja active Pending
- 1999-03-22 BR BR9909342-1A patent/BR9909342A/pt not_active Application Discontinuation
- 1999-03-22 ES ES99909069T patent/ES2283105T3/es not_active Expired - Lifetime
- 1999-03-22 WO PCT/FR1999/000666 patent/WO1999051269A1/fr not_active Ceased
- 1999-03-22 AU AU28448/99A patent/AU744964B2/en not_active Expired
- 1999-03-22 AT AT99909069T patent/ATE353670T1/de active
- 1999-03-22 DE DE69935136T patent/DE69935136T2/de not_active Expired - Lifetime
- 1999-03-22 PL PL99343602A patent/PL194348B1/pl unknown
- 1999-03-22 DK DK99909069T patent/DK1066055T3/da active
- 1999-03-22 PT PT99909069T patent/PT1066055E/pt unknown
- 1999-03-31 ZA ZA9902478A patent/ZA992478B/xx unknown
- 1999-03-31 AR ARP990101458A patent/AR037062A1/es unknown
-
2000
- 2000-10-02 US US09/677,672 patent/US7163926B1/en not_active Expired - Lifetime
-
2007
- 2007-05-09 CY CY20071100615T patent/CY1108013T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1108013T1 (el) | 2013-09-04 |
| EP1066055B1 (fr) | 2007-02-14 |
| DE69935136D1 (de) | 2007-03-29 |
| AR037062A1 (es) | 2004-10-20 |
| ATE353670T1 (de) | 2007-03-15 |
| US7163926B1 (en) | 2007-01-16 |
| CA2327389C (en) | 2011-06-14 |
| ES2283105T3 (es) | 2007-10-16 |
| AU744964B2 (en) | 2002-03-07 |
| ZA992478B (en) | 2000-10-10 |
| JP2002510651A (ja) | 2002-04-09 |
| PL343602A1 (en) | 2001-08-27 |
| FR2776928B1 (fr) | 2000-06-23 |
| PL194348B1 (pl) | 2007-05-31 |
| EP1066055A1 (fr) | 2001-01-10 |
| DK1066055T3 (da) | 2007-06-11 |
| AU2844899A (en) | 1999-10-25 |
| WO1999051269A1 (fr) | 1999-10-14 |
| PT1066055E (pt) | 2007-05-31 |
| DE69935136T2 (de) | 2007-11-29 |
| CA2327389A1 (en) | 1999-10-14 |
| FR2776928A1 (fr) | 1999-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |