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BR9908861A - Cyclooctadepsipeptides and their use to combat endoparasites - Google Patents

Cyclooctadepsipeptides and their use to combat endoparasites

Info

Publication number
BR9908861A
BR9908861A BR9908861-4A BR9908861A BR9908861A BR 9908861 A BR9908861 A BR 9908861A BR 9908861 A BR9908861 A BR 9908861A BR 9908861 A BR9908861 A BR 9908861A
Authority
BR
Brazil
Prior art keywords
cyclooctadepsipeptides
endoparasites
preparation
combat
combat endoparasites
Prior art date
Application number
BR9908861-4A
Other languages
Portuguese (pt)
Inventor
Hubert Dyker
Ralf-Ingo Schenkel
Juergen Scherkenbeck
Achim Harder
Norbert Mencke
Georg Von Samson-Himmelstjerna
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BR9908861A publication Critical patent/BR9908861A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Patente de Invenção: <B>"CICLOOCTADEPSIPEPTìDEOS E SEU USO PARA O COMBATE DE ENDOPARASITAS"<D>. A invenção refere-se a novos ciclooctadepsipeptídeos da fórmula (I), em que R¹ representa ciano, heterociclila ligada com C-C ou alquenila, alquinila ou arila eventualmente substituídas e R² representa hidrogênio ou representa o mesmo radical que R¹, processo para a sua preparação, produtos intermediários para a sua preparação e seu uso para o combate de endoparasitas e agentes contendo estas substâncias ativas.Invention Patent: <B> "CYCLEOCTADEPSIPEPTIDES AND THEIR USE FOR COMBATING ENDOPARASITES" <D>. The invention relates to new cyclooctadepsipeptides of formula (I), in which R¹ represents cyano, heterocyclyl linked with CC or alkenyl, alkynyl or aryl possibly substituted and R² represents hydrogen or represents the same radical as R¹, process for its preparation, intermediate products for their preparation and their use to fight endoparasites and agents containing these active substances.

BR9908861-4A 1998-03-17 1999-03-04 Cyclooctadepsipeptides and their use to combat endoparasites BR9908861A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19811559A DE19811559A1 (en) 1998-03-17 1998-03-17 New substituted derivatives of cyclooctadepsipeptide PF1022, useful as parasiticides, especially anthelmintics
PCT/EP1999/001407 WO1999047506A1 (en) 1998-03-17 1999-03-04 Cyclooctadepsipeptides and their use for combating endoparasites

Publications (1)

Publication Number Publication Date
BR9908861A true BR9908861A (en) 2000-11-21

Family

ID=7861200

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9908861-4A BR9908861A (en) 1998-03-17 1999-03-04 Cyclooctadepsipeptides and their use to combat endoparasites

Country Status (10)

Country Link
EP (1) EP1064272A1 (en)
JP (1) JP2002506857A (en)
KR (1) KR20010041450A (en)
CN (1) CN1293664A (en)
AU (1) AU3143899A (en)
BR (1) BR9908861A (en)
CA (1) CA2323628A1 (en)
DE (1) DE19811559A1 (en)
PL (1) PL342948A1 (en)
WO (1) WO1999047506A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008030764A1 (en) 2008-06-28 2009-12-31 Bayer Animal Health Gmbh Combination of amidine derivatives with cyclic depsipeptides
DE102009012423A1 (en) 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Preparation based on oil
DE102010064245A1 (en) 2010-12-28 2012-06-28 Bayer Animal Health Gmbh Use of macrocyclic lactones used in controlling endoparasitic filariae and gastrointestinal nematodes, particularly used in controlling heartworm
WO2012028556A1 (en) 2010-08-31 2012-03-08 Bayer Animal Health Gmbh Macrocyclic lactones and their use and their combinations with other active substances
BR112017024773A2 (en) * 2015-05-20 2018-11-06 Merial, Inc. anthelmintic depsipeptide compounds
HK1255391A1 (en) 2015-12-28 2019-08-16 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
AU2019266197B2 (en) * 2018-05-10 2023-03-02 Zoetis Services Llc Endoparasitic depsipeptides
EP4538282A1 (en) * 2023-10-13 2025-04-16 Vetoquinol SA Synthesis of emodepside

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69331414T2 (en) * 1992-03-17 2002-08-08 Fujisawa Pharmaceutical Co., Ltd. DEPSIPEPTIDE, PRODUCTION AND APPLICATION
EP0685469A4 (en) * 1993-02-19 1996-04-03 Meiji Seika Kaisha Pf1022 derivative, cyclic depsipeptide.
DE4317457A1 (en) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptides with endoparasiticidal activity
ATE299871T1 (en) * 1995-09-22 2005-08-15 Meiji Seika Kaisha NEW CYCLIC DEPSIPEPTIDE PF1022 DERIVATIVES
DE19545639A1 (en) * 1995-12-07 1997-06-12 Bayer Ag Process for the preparation of substituted aryl lactic acid-containing cyclodepsipeptides with 24 ring atoms

Also Published As

Publication number Publication date
EP1064272A1 (en) 2001-01-03
JP2002506857A (en) 2002-03-05
KR20010041450A (en) 2001-05-25
PL342948A1 (en) 2001-07-16
AU3143899A (en) 1999-10-11
DE19811559A1 (en) 1999-09-23
CA2323628A1 (en) 1999-09-23
WO1999047506A1 (en) 1999-09-23
CN1293664A (en) 2001-05-02

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTA A 5O, 6O, 7O E 8O ANUIDADES.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007.