BR9814604A - "ponteiras em fase sólida e seus usos" - Google Patents
"ponteiras em fase sólida e seus usos"Info
- Publication number
- BR9814604A BR9814604A BR9814604-1A BR9814604A BR9814604A BR 9814604 A BR9814604 A BR 9814604A BR 9814604 A BR9814604 A BR 9814604A BR 9814604 A BR9814604 A BR 9814604A
- Authority
- BR
- Brazil
- Prior art keywords
- solid
- phase
- tips
- biomolecule
- diagnosis
- Prior art date
Links
- 239000007790 solid phase Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 abstract 3
- 238000004458 analytical method Methods 0.000 abstract 2
- 230000000712 assembly Effects 0.000 abstract 2
- 238000000429 assembly Methods 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 2
- 206010071602 Genetic polymorphism Diseases 0.000 abstract 1
- 208000026350 Inborn Genetic disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000005755 formation reaction Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 208000016361 genetic disease Diseases 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 244000000010 microbial pathogen Species 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000002764 solid phase assay Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- 244000052613 viral pathogen Species 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00387—Applications using probes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/0047—Pins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/0047—Pins
- B01J2219/00472—Replaceable crowns
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00504—Pins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00504—Pins
- B01J2219/00506—Pins with removable crowns
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
"PONTEIRAS EM FASE SóLIDA E SEUS USOS" Os ensaios em fase sólida têm proporcionado uma abordagem preciosa para a análise de biomoléculas em diagnósticos médicos e em pesquisa básica. Os métodos de hibridização de ácidos nucléicos em fase sólida, por exemplo, têm sido aplicados para a análise de polimorfismos genéticos, diagnóstico de doença genética, diagnóstico de câncer, detecção de patógenos virais e microbianos, seleção de clones, e ordenamento de fragmentos genómicos. Uma nova ponteira retentora de amostras em fase sólida proporciona procedimentos aperfeiçoados para sintetizar ou detectar uma biomolécula. Essas ponteiras podem ser usadas para projetar conjuntos retentores de amostras, que por sua vez, podem ser combinados, para formar formações de conjuntos retentores de amostras em fase sólida, úties nos processos automatizados. as ponteiras podem ser conectáveis a um pino de suporte de mola de propensão e contêm também uma camada química que reveste a dita ponteira à qual a biomolécula pode ser ligada.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7029097P | 1997-12-31 | 1997-12-31 | |
| PCT/US1998/027850 WO1999034214A1 (en) | 1997-12-31 | 1998-12-30 | Solid-phase tips and uses relating thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9814604A true BR9814604A (pt) | 2000-10-17 |
Family
ID=22094390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9814604-1A BR9814604A (pt) | 1997-12-31 | 1998-12-30 | "ponteiras em fase sólida e seus usos" |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1040352A1 (pt) |
| JP (1) | JP2002500362A (pt) |
| CN (1) | CN1284168A (pt) |
| AU (1) | AU2098999A (pt) |
| BR (1) | BR9814604A (pt) |
| CA (1) | CA2315296A1 (pt) |
| HU (1) | HUP0100697A2 (pt) |
| WO (1) | WO1999034214A1 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000029112A1 (en) * | 1998-11-18 | 2000-05-25 | Orchid Biosciences, Inc. | One-step nucleic acid dipstick device with movable membrane |
| NL1012394C2 (nl) * | 1999-06-21 | 2000-12-22 | Inst F R Biotechnologie | Werkwijze en inrichting voor het gelijktijdig en onafhankelijk van elkaar bemonsteren van ingevroren cultures van micro-organismen en/of eukaryote cellen. |
| EP1212138B1 (en) * | 1999-08-17 | 2005-06-08 | TTP LabTech Ltd | Sampling/dispensing device with plunger and housing set onto plunger |
| WO2001019518A1 (en) * | 1999-09-13 | 2001-03-22 | Aclara Biosciences, Inc. | Surface tension loading inertial release droplet device and method |
| JP2001136964A (ja) * | 1999-11-12 | 2001-05-22 | Shimadzu Corp | Pcrプレート及びdnaチップの作製方法 |
| JP2004502138A (ja) * | 2000-06-28 | 2004-01-22 | イルミナ インコーポレイテッド | ハイブリダイゼーションチャンバーと微小球を利用した複合アレイ |
| JP2003091787A (ja) * | 2001-09-17 | 2003-03-28 | Riken Keiki Co Ltd | 可搬式ガス警報器 |
| US7142987B2 (en) * | 2001-11-07 | 2006-11-28 | Genvault Corporation | Apparatus, system, and method of archival and retrieval of samples |
| US7584240B2 (en) | 2001-11-07 | 2009-09-01 | Genvault Corporation | Automated biological sample archive for storage, retrieval and analysis of large numbers of samples for remote clients |
| US7718442B2 (en) | 2002-11-22 | 2010-05-18 | Genvault Corporation | Sealed sample storage element system and method |
| DE602005016402D1 (de) | 2004-05-24 | 2009-10-15 | Genvault Corp | Stabile lagerung von protein und stabile lagerung von nukleinsäure in wiedergewinnbarer form |
| WO2008154225A2 (en) | 2007-06-06 | 2008-12-18 | Bayer Healthcare Llc | Microdeposition system for a biosensor |
| US20110183407A1 (en) * | 2008-03-12 | 2011-07-28 | Cellectricon Ab | Apparatus and method for tip alignment in multiwell plates |
| US8283165B2 (en) | 2008-09-12 | 2012-10-09 | Genvault Corporation | Matrices and media for storage and stabilization of biomolecules |
| GB201010237D0 (en) * | 2010-06-18 | 2010-07-21 | Lgc Ltd | Methods and apparatuses |
| JP6012767B2 (ja) | 2012-02-07 | 2016-10-25 | ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー | 基板、ペプチドアレイ、および方法 |
| US10006909B2 (en) | 2012-09-28 | 2018-06-26 | Vibrant Holdings, Llc | Methods, systems, and arrays for biomolecular analysis |
| EP3974564A1 (en) * | 2012-09-28 | 2022-03-30 | Vibrant Holdings, LLC | Methods, systems, and arrays for biomolecular analysis |
| US10286376B2 (en) | 2012-11-14 | 2019-05-14 | Vibrant Holdings, Llc | Substrates, systems, and methods for array synthesis and biomolecular analysis |
| JP5597731B2 (ja) * | 2013-01-04 | 2014-10-01 | あおい精機株式会社 | 検査前処理装置 |
| EP2956771B1 (en) | 2013-02-15 | 2020-04-08 | Vibrant Holdings, LLC | Methods and compositions for amplified electrochemiluminescence detection |
| US10538808B2 (en) | 2017-05-26 | 2020-01-21 | Vibrant Holdings, Llc | Photoactive compounds and methods for biomolecule detection and sequencing |
| JP7422087B2 (ja) | 2018-05-09 | 2024-01-25 | ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー | 光活性化された作用物質を使用してポリヌクレオチドアレイを合成する方法 |
| WO2021110079A1 (en) * | 2019-12-03 | 2021-06-10 | Bgi Shenzhen Co., Ltd. | Immersion synthesis of oligonucleotides |
| CN112162027B (zh) * | 2020-09-21 | 2023-08-18 | 上海市计量测试技术研究院 | 一种基于三嵌段探针的电化学传感器及其在检测转基因双链rna中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2197720A (en) * | 1986-11-20 | 1988-05-25 | Nat Res Dev | Immobilisation of polynucleotides |
| EP0498801B1 (en) * | 1989-09-15 | 1998-11-04 | Chiron Mimotopes Pty. Ltd. | Solid surface for peptide synthesis |
| SE467308B (sv) * | 1990-10-22 | 1992-06-29 | Berol Nobel Ab | Fast yta belagd med ett hydrofilt ytterskikt med kovalent bundna biopolymerer, saett att framstaella en saadan yta och ett konjugat daerfoer |
| EP0672049A4 (en) * | 1992-11-06 | 1997-10-15 | Chiron Mimotopes Pty Ltd | SUPPORT FOR THE SYNTHESIS OF MODULE POLYMERS. |
| CA2279232A1 (en) * | 1996-10-04 | 1998-04-09 | Gordon, Steven J. | Replaceable elements for a parallel sequential bio-polymer synthesis device |
| WO1999004896A1 (en) * | 1997-07-22 | 1999-02-04 | Rapigene, Inc. | Polyethylenimine-based biomolecule arrays |
| WO1999005308A2 (en) * | 1997-07-22 | 1999-02-04 | Rapigene, Inc. | Apparatus and methods for arraying solution onto a solid support |
| DE19742227A1 (de) * | 1997-09-25 | 1999-04-01 | Juergen Prof Dipl Phys Wolfrum | Verfahren zum Sequenzieren eines einzelnen DNA-Moleküls |
-
1998
- 1998-12-30 HU HU0100697A patent/HUP0100697A2/hu unknown
- 1998-12-30 EP EP98965546A patent/EP1040352A1/en not_active Withdrawn
- 1998-12-30 AU AU20989/99A patent/AU2098999A/en not_active Abandoned
- 1998-12-30 BR BR9814604-1A patent/BR9814604A/pt not_active Application Discontinuation
- 1998-12-30 WO PCT/US1998/027850 patent/WO1999034214A1/en not_active Ceased
- 1998-12-30 CN CN98813351A patent/CN1284168A/zh active Pending
- 1998-12-30 CA CA002315296A patent/CA2315296A1/en not_active Abandoned
- 1998-12-30 JP JP2000526814A patent/JP2002500362A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1040352A1 (en) | 2000-10-04 |
| HUP0100697A2 (hu) | 2001-06-28 |
| CN1284168A (zh) | 2001-02-14 |
| JP2002500362A (ja) | 2002-01-08 |
| WO1999034214A1 (en) | 1999-07-08 |
| AU2098999A (en) | 1999-07-19 |
| CA2315296A1 (en) | 1999-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |