BR9814549A - "composição farmacêutica contendo cloridrato de bupropion e um estabilizador" - Google Patents
"composição farmacêutica contendo cloridrato de bupropion e um estabilizador"Info
- Publication number
- BR9814549A BR9814549A BR9814549-5A BR9814549A BR9814549A BR 9814549 A BR9814549 A BR 9814549A BR 9814549 A BR9814549 A BR 9814549A BR 9814549 A BR9814549 A BR 9814549A
- Authority
- BR
- Brazil
- Prior art keywords
- bupropion hydrochloride
- stabilizer
- pharmaceutical composition
- composition containing
- containing bupropion
- Prior art date
Links
- IKBZAUYPBWFMDI-UHFFFAOYSA-N 5-bromo-4-methoxy-7-methyl-2,3-dihydro-1h-indene Chemical compound C1=C(Br)C(OC)=C2CCCC2=C1C IKBZAUYPBWFMDI-UHFFFAOYSA-N 0.000 title abstract 6
- 229960004367 bupropion hydrochloride Drugs 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003381 stabilizer Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"COMPOSIçãO FARMACêUTICA CONTENDO CLORIDRATO DE BUPROPION E UM ESTABILIZADOR"<D>. São providenciadas novas e estáveis formulações de cloridrato de bupropion, as quais manterão pelo menos 80% da potência do cloridrato de bupropion inicial após um ano. Métodos de inibir a degradação do cloridrato de bupropion e métodos para preparar formulações estáveis de cloridrato de bupropion também são providenciados.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/000,999 US6221917B1 (en) | 1997-12-30 | 1997-12-30 | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
| PCT/US1998/027620 WO1999033457A1 (en) | 1997-12-30 | 1998-12-23 | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9814549A true BR9814549A (pt) | 2000-10-10 |
Family
ID=21693907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9814549-5A BR9814549A (pt) | 1997-12-30 | 1998-12-23 | "composição farmacêutica contendo cloridrato de bupropion e um estabilizador" |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6221917B1 (pt) |
| EP (1) | EP1043985A1 (pt) |
| AU (1) | AU2015499A (pt) |
| BR (1) | BR9814549A (pt) |
| CA (1) | CA2316981C (pt) |
| WO (1) | WO1999033457A1 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6153223A (en) * | 1998-06-05 | 2000-11-28 | Watson Pharmaceuticals, Inc. | Stabilized pharmaceutical compositions |
| TR200100366T2 (tr) * | 1998-08-07 | 2001-11-21 | Emisphere Technologies, Inc. | Aktif madde dağıtmaya mahsus bileşikler ve bileşimler. |
| US8545880B2 (en) * | 1999-02-26 | 2013-10-01 | Andrx Pharmaceuticals, Llc | Controlled release oral dosage form |
| US6280763B1 (en) | 1999-05-10 | 2001-08-28 | Pierce Management, Llc | Apparatus and method for transdermal delivery of bupropion |
| US6312716B1 (en) * | 1999-05-10 | 2001-11-06 | Peierce Management Llc | Patch and method for transdermal delivery of bupropion base |
| US6306436B1 (en) | 2000-04-28 | 2001-10-23 | Teva Pharmaceuticals Usa, Inc. | Stabilized, acid-free formulation for sustained release of bupropion hydrochloride |
| AU2003280065A1 (en) * | 2002-11-15 | 2004-06-15 | Eads Astrium Limited | Bupropion hydrochloride solid dosage forms |
| US6893660B2 (en) * | 2002-11-21 | 2005-05-17 | Andrx Pharmaceuticals, Inc. | Stable pharmaceutical compositions without a stabilizer |
| NZ544281A (en) * | 2003-08-08 | 2008-07-31 | Biovail Lab Int Srl | Modified-release tablet of bupropion hydrochloride |
| US20050096311A1 (en) * | 2003-10-30 | 2005-05-05 | Cns Response | Compositions and methods for treatment of nervous system disorders |
| US20060099262A1 (en) * | 2004-11-08 | 2006-05-11 | Biokey, Inc. | Methods and formulations for making controlled release oral dosage form |
| US8586085B2 (en) * | 2004-11-08 | 2013-11-19 | Biokey, Inc. | Methods and formulations for making pharmaceutical compositions containing bupropion |
| KR100670798B1 (ko) | 2004-12-17 | 2007-01-17 | 한국전자통신연구원 | 데이터베이스 캐시 시스템 |
| US20060204571A1 (en) * | 2005-03-12 | 2006-09-14 | Sun Pharmaceutical Industries Limited | Stable compositions of bupropion or its pharmaceutically acceptable salts |
| US7884136B2 (en) * | 2005-06-27 | 2011-02-08 | Biovail Laboratories International S.R.L. | Modified-release formulations of a bupropion salt |
| US8703191B2 (en) * | 2006-07-25 | 2014-04-22 | Intelgenx Corp. | Controlled-release pharmaceutical tablets |
| US7674479B2 (en) * | 2006-07-25 | 2010-03-09 | Intelgenx Corp. | Sustained-release bupropion and bupropion/mecamylamine tablets |
| PL2101733T3 (pl) * | 2006-12-13 | 2013-02-28 | Hoffmann La Roche | Preparat w postaci proszku walgancyklowiru |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| US20110136815A1 (en) | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| JP5917964B2 (ja) * | 2012-03-19 | 2016-05-18 | 富士ゼロックス株式会社 | 錠剤、錠剤の製造方法、錠剤管理装置、錠剤照合装置及びプログラム |
| WO2014181280A1 (en) * | 2013-05-08 | 2014-11-13 | Genovo Development Services Limited | Stable compositions of etifoxine and its salts |
| USD1033704S1 (en) * | 2022-05-11 | 2024-07-02 | Coast Cutlery Co. | Flashlight |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759838A (fr) * | 1969-12-04 | 1971-06-03 | Wellcome Found | Cetones a activite biologique |
| US3885046A (en) | 1969-12-04 | 1975-05-20 | Burroughs Wellcome Co | Meta chloro or fluoro substituted alpha-T-butylaminopropionphenones in the treatment of depression |
| USRE33994E (en) | 1983-08-16 | 1992-07-14 | Burroughs Wellcome Co. | Pharmaceutical delivery system |
| GB9217295D0 (en) | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| GB9315856D0 (en) * | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| US5358970A (en) * | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
-
1997
- 1997-12-30 US US09/000,999 patent/US6221917B1/en not_active Expired - Lifetime
-
1998
- 1998-12-23 AU AU20154/99A patent/AU2015499A/en not_active Abandoned
- 1998-12-23 EP EP98964940A patent/EP1043985A1/en not_active Withdrawn
- 1998-12-23 CA CA002316981A patent/CA2316981C/en not_active Expired - Lifetime
- 1998-12-23 BR BR9814549-5A patent/BR9814549A/pt not_active IP Right Cessation
- 1998-12-23 WO PCT/US1998/027620 patent/WO1999033457A1/en not_active Ceased
-
1999
- 1999-09-28 US US09/406,906 patent/US6242496B1/en not_active Expired - Lifetime
-
2001
- 2001-04-02 US US09/824,371 patent/US6482987B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015499A (en) | 1999-07-19 |
| CA2316981A1 (en) | 1999-07-08 |
| US6221917B1 (en) | 2001-04-24 |
| US6242496B1 (en) | 2001-06-05 |
| US20010021721A1 (en) | 2001-09-13 |
| EP1043985A1 (en) | 2000-10-18 |
| CA2316981C (en) | 2007-08-07 |
| WO1999033457A1 (en) | 1999-07-08 |
| US6482987B2 (en) | 2002-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: WYETH (US) Free format text: ALTERADO DE: AMERICAN HOME PRODUCTS CORPORATION |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFARENTE A 7O E 8O ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007. |