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BR9814310A - Processo de cloropirimidina - Google Patents

Processo de cloropirimidina

Info

Publication number
BR9814310A
BR9814310A BR9814310-7A BR9814310A BR9814310A BR 9814310 A BR9814310 A BR 9814310A BR 9814310 A BR9814310 A BR 9814310A BR 9814310 A BR9814310 A BR 9814310A
Authority
BR
Brazil
Prior art keywords
compound
chloropyrimidine
phosphorus oxychloride
compounds
trialkylamine
Prior art date
Application number
BR9814310-7A
Other languages
English (en)
Inventor
Ronald Bruce Leng
James William Ringer
Julie Lynn Maurier
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of BR9814310A publication Critical patent/BR9814310A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO DE CLOROPIRIMIDINA"<D>. Compostos de cloropirimidina, tais como 4,6-dicloro-2-etoxipirimidina, foram preparados em bom rendimento e boa pureza dos compostos de hidroxipirimidina correspondentes na ausência de solventes orgânicos e com uma quantidade reduzida de oxicloreto de fósforo realizando a reação na presença de um composto de trialquilamina e tricloreto de fósforo. As adições de composto de hidroxipirimidina e composto de trialquilamina poderiam ser feitas em reagentes. Os compostos de cloropirimidina produzidos foram recuperados em um modo aperfeiçoado adicionando cloro para converter os subprodutos de ácido clorofosfórico e tricloreto de fósforo a oxicloreto de fósforo, diluindo a mistura com composto de cloropirimidina adicional sendo produzido e removendo o oxicloreto de fósforo por destilação, combinando o resíduo com água e uma base, destilando o composto de trialquilamina da mistura resultante, e removendo a fase aquosa.
BR9814310-7A 1997-12-19 1998-12-18 Processo de cloropirimidina BR9814310A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6820397P 1997-12-19 1997-12-19
PCT/US1998/027145 WO1999032458A1 (en) 1997-12-19 1998-12-18 Chloropyrimidine process

Publications (1)

Publication Number Publication Date
BR9814310A true BR9814310A (pt) 2000-10-10

Family

ID=22081073

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814310-7A BR9814310A (pt) 1997-12-19 1998-12-18 Processo de cloropirimidina

Country Status (10)

Country Link
US (1) US6066734A (pt)
EP (1) EP1042303B1 (pt)
JP (1) JP2001526272A (pt)
CN (1) CN1133624C (pt)
AT (1) ATE232203T1 (pt)
AU (1) AU1935299A (pt)
BR (1) BR9814310A (pt)
DE (1) DE69811276T2 (pt)
DK (1) DK1042303T3 (pt)
WO (1) WO1999032458A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03008121A (es) 2001-03-15 2003-12-12 Basf Ag 5-fenilpirimidinas, metodos y productos intermedios para su produccion y uso de las mismas para controlar hongos patogenicos.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789763A (fr) * 1971-10-08 1973-04-06 Ciba Geigy Procede de regeneration de l'oxychlorure ou -bromure de phosphore a partir de melanges reactionnels
US5057517A (en) * 1987-07-20 1991-10-15 Merck & Co., Inc. Piperazinyl derivatives of purines and isosteres thereof as hypoglycemic agents
WO1995007265A1 (en) * 1993-09-10 1995-03-16 E.I. Du Pont De Nemours And Company Improved process for preparing 2-amino-4,6-dichloropyrimidine
DE4408404A1 (de) * 1994-03-12 1995-09-14 Huels Chemische Werke Ag Verfahren zur Herstellung von Chlorpyrimidinen
AT402924B (de) * 1994-05-13 1997-09-25 Chemie Linz Gmbh Verfahren zur herstellung von 2-amino-4,6-dichloro-pyrimidin
DE4429466A1 (de) * 1994-08-19 1996-02-22 Bayer Ag Verfahren zur Herstellung von Polychlorpyrimidinen
EP0807106B1 (en) * 1995-01-30 2001-10-17 Syngenta Limited Process for preparing 4,6-dichloro-pyrimidine
AT402818B (de) * 1995-06-02 1997-09-25 Chemie Linz Gmbh Verfahren zur herstellung von reinem 4,6-dichlorpyrimidin
DE19521036A1 (de) * 1995-06-09 1996-12-12 Bayer Ag Verfahren zur Herstellung von 2,4,6-Trichlorpyrimidin
DE19531299A1 (de) * 1995-08-25 1997-02-27 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidinen

Also Published As

Publication number Publication date
CN1284067A (zh) 2001-02-14
EP1042303A1 (en) 2000-10-11
EP1042303B1 (en) 2003-02-05
CN1133624C (zh) 2004-01-07
DE69811276T2 (de) 2003-07-10
AU1935299A (en) 1999-07-12
US6066734A (en) 2000-05-23
DE69811276D1 (de) 2003-03-13
WO1999032458A1 (en) 1999-07-01
ATE232203T1 (de) 2003-02-15
JP2001526272A (ja) 2001-12-18
DK1042303T3 (da) 2003-06-10

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements