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BR9812525A - Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae - Google Patents

Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae

Info

Publication number
BR9812525A
BR9812525A BR9812525-7A BR9812525A BR9812525A BR 9812525 A BR9812525 A BR 9812525A BR 9812525 A BR9812525 A BR 9812525A BR 9812525 A BR9812525 A BR 9812525A
Authority
BR
Brazil
Prior art keywords
human complement
proteinase
streptococcus pneumoniae
degrading
degrading proteinase
Prior art date
Application number
BR9812525-7A
Other languages
English (en)
Inventor
Margaret K Hostetter
David J Finkel
Qi Cheng
Bruce A Green
Amy W Masi
Original Assignee
Univ Minnesota
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota, American Cyanamid Co filed Critical Univ Minnesota
Publication of BR9812525A publication Critical patent/BR9812525A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Patente de Invenção: <B>"PROTEINASE DEGRADADORA DE COMPLEMENTO HUMANO C3 DE STREPTOCOCCUS PNEUMONIAE"<D>. A presente invenção refere-se à identificação e ao uso de uma família de proteinases degradadoras de complemento humano C3, expressadas por S. pneumoniae. A proteinase tem um peso molecular de cerca de 15 kDa a cerca de 25 kDa. Uma proteinase preferida desta invenção inclui a seq³ência de aminoácidos de SEQ ID NO: 2.
BR9812525-7A 1997-09-24 1998-09-24 Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae BR9812525A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5990797P 1997-09-24 1997-09-24
PCT/US1998/020186 WO1999015675A1 (en) 1997-09-24 1998-09-24 HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM $i(STREPTOCOCCUS PNEUMONIAE)

Publications (1)

Publication Number Publication Date
BR9812525A true BR9812525A (pt) 2000-07-25

Family

ID=22026061

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812525-7A BR9812525A (pt) 1997-09-24 1998-09-24 Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae

Country Status (8)

Country Link
EP (1) EP1017828A1 (pt)
JP (1) JP2001517449A (pt)
KR (1) KR20010024299A (pt)
CN (1) CN1291233A (pt)
AU (1) AU9510598A (pt)
BR (1) BR9812525A (pt)
CA (1) CA2305016A1 (pt)
WO (1) WO1999015675A1 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245335B1 (en) 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
US6420135B1 (en) * 1996-10-31 2002-07-16 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
US6676943B1 (en) 1997-04-24 2004-01-13 Regents Of The University Of Minnesota Human complement C3-degrading protein from Streptococcus pneumoniae
US6936252B2 (en) 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
EP1783224A3 (en) * 1998-07-27 2007-08-15 Sanofi Pasteur Limited Streptococcus pneumoniae proteins and nucleic acid molecules
JP2002526082A (ja) * 1998-09-24 2002-08-20 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ストレプトコッカス・ニューモニア由来のヒト補体ｃ３分解ポリペプチド
JP4689044B2 (ja) * 1998-12-21 2011-05-25 メディミューン，インコーポレーテッド ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片
CA2356836C (en) * 1998-12-23 2011-09-13 Shire Biochem Inc. Novel streptococcus antigens
AU2005209689B2 (en) * 1998-12-23 2008-07-17 Id Biomedical Corporation Of Quebec Novel streptococcus antigens
EP1950302B1 (en) * 1998-12-23 2012-12-05 ID Biomedical Corporation of Quebec Streptococcus antigens
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
US7074415B2 (en) 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
AU2001270381B2 (en) * 2000-06-20 2007-05-24 Id Biomedical Corporation Streptococcus antigens
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
US7118756B2 (en) 2000-12-28 2006-10-10 Wyeth Recombinant protective protein from Streptococcus pneumoniae
EP1456231A2 (en) 2001-12-20 2004-09-15 Shire Biochem Inc. Streptococcus antigens
EP2428218A1 (en) * 2005-10-21 2012-03-14 Catalyst Biosciences, Inc. Modified proteases that inhibit complement activation
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
PT1973564T (pt) 2005-12-22 2017-01-24 Glaxosmithkline Biologicals Sa Vacina compreendendo conjugados polissacarídicos capsulares de streptococcus pneumoniae
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
AU2008267208B2 (en) 2007-06-26 2012-01-19 Glaxosmithkline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
BRPI0910963A2 (pt) 2008-04-16 2016-01-05 Glaxosmithkline Biolog Sa composição imunogênica, método para tratar ou prevenir doença pneumocócica, e , uso de uma composição imunogênica
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
CN103533953A (zh) 2011-05-17 2014-01-22 葛兰素史密丝克莱恩生物有限公司 针对肺炎链球菌的疫苗
CN102731739B (zh) * 2012-07-05 2013-11-06 富阳经略化工技术有限公司 用作润滑油粘度指数改进剂的星形聚合物及其制备方法和应用
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420135B1 (en) * 1996-10-31 2002-07-16 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
AU740153B2 (en) * 1997-04-24 2001-11-01 Regents Of The University Of Minnesota Human complement C3-degrading proteinase from streptococcus pneumoniae

Also Published As

Publication number Publication date
JP2001517449A (ja) 2001-10-09
KR20010024299A (ko) 2001-03-26
CN1291233A (zh) 2001-04-11
AU9510598A (en) 1999-04-12
CA2305016A1 (en) 1999-04-01
WO1999015675A1 (en) 1999-04-01
EP1017828A1 (en) 2000-07-12

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]