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BR9811849A - Regiões de fixação com a matriz - Google Patents

Regiões de fixação com a matriz

Info

Publication number
BR9811849A
BR9811849A BR9811849-8A BR9811849A BR9811849A BR 9811849 A BR9811849 A BR 9811849A BR 9811849 A BR9811849 A BR 9811849A BR 9811849 A BR9811849 A BR 9811849A
Authority
BR
Brazil
Prior art keywords
matrix
fixing regions
regions
attachment regions
fixing
Prior art date
Application number
BR9811849-8A
Other languages
English (en)
Inventor
Susan Margaret Michalowski
Steven L Spiker
Original Assignee
Univ North Carolina State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina State filed Critical Univ North Carolina State
Publication of BR9811849A publication Critical patent/BR9811849A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/822—Reducing position variability, e.g. by the use of scaffold attachment region/matrix attachment region (SAR/MAR); Use of SAR/MAR to regulate gene expression

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>"REGIõES DE FIXAçãO COM A MATRIZ"<D>. Estão descritas regiões de fixação com a matriz isoladas a partir de vegetais superiores e de estruturas de DNA e vetores contendo tais regiões de fixação com a matriz. é provido um método para a identificação das regiões de fixação com a matriz.
BR9811849-8A 1997-08-06 1998-08-05 Regiões de fixação com a matriz BR9811849A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6611897P 1997-08-06 1997-08-06
PCT/US1998/016344 WO1999007866A1 (en) 1997-08-06 1998-08-05 Matrix attachment regions

Publications (1)

Publication Number Publication Date
BR9811849A true BR9811849A (pt) 2000-08-08

Family

ID=22067358

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811849-8A BR9811849A (pt) 1997-08-06 1998-08-05 Regiões de fixação com a matriz

Country Status (8)

Country Link
US (2) US6245974B1 (pt)
EP (1) EP1005560A1 (pt)
JP (1) JP2001520861A (pt)
AR (1) AR013400A1 (pt)
AU (1) AU749014B2 (pt)
BR (1) BR9811849A (pt)
CA (1) CA2298052A1 (pt)
WO (1) WO1999007866A1 (pt)

Families Citing this family (33)

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DE19848017A1 (de) * 1998-10-17 2000-04-20 Multigene Biotech Gmbh Episomal replizierender Vektor zur Expression eines Transgens in Säugerzellen
DE19942149A1 (de) * 1999-09-03 2001-03-15 Daniele Zink Verfahren zur Expression von exogenen Sequenzen in Säugerzellen
KR100408844B1 (ko) 2000-07-29 2003-12-06 한국산업기술평가원 동물세포 발현벡터
CA2435972C (en) 2001-01-26 2011-09-13 University Of Lausanne Matrix attachment regions and methods for use thereof
US6933136B2 (en) 2002-09-20 2005-08-23 Novo Nordisk A/S Method for making recombinant proteins
KR101229989B1 (ko) 2003-10-24 2013-02-06 셀렉시스 에스. 에이. Ｍａｒ 서열의 복합 트랜스펙션 방법에 의한 포유동물 세포에서의 고효율 유전자 전달 및 발현
US8086519B2 (en) 2004-10-14 2011-12-27 Cfph, Llc System and method for facilitating a wireless financial transaction
KR20060096383A (ko) * 2005-03-04 2006-09-11 주식회사 셀트리온 １ 카피 이상의 ｍａｒ ｄｎａ 서열이 유전자의전사종결영역의 3′말단에 삽입된 동물세포 발현 벡터 및그를 이용한 외래 유전자의 발현 방법
IN2012DN01800A (pt) * 2009-08-19 2015-06-05 Dow Agrosciences Llc
US9204599B2 (en) 2009-08-19 2015-12-08 Dow Agrosciences Llc Detection of AAD1 event DAS-40278-9
EP2503871B1 (en) * 2009-11-24 2017-06-14 Dow AgroSciences LLC Aad-12 event 416, related transgenic soybean lines, and event-specific identification thereof
CA2849318C (en) 2011-09-22 2019-11-12 Amgen Inc. Cd27l antigen binding proteins
AR091069A1 (es) 2012-05-18 2014-12-30 Amgen Inc Proteinas de union a antigeno dirigidas contra el receptor st2
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
US9546203B2 (en) 2013-03-14 2017-01-17 Amgen Inc. Aglycosylated Fc-containing polypeptides with cysteine substitutions
WO2014144817A2 (en) 2013-03-15 2014-09-18 Amgen Inc. Inhibitory polypeptides specific to wnt inhibitors
NZ753995A (en) 2013-05-30 2022-07-01 Kiniksa Pharmaceuticals Ltd Oncostatin m receptor antigen binding proteins
MX2016002870A (es) 2013-09-05 2017-02-23 Amgen Inc Moleculas que contienen fc que presentan perfiles de glicoforma predecibles, consistentes y reproducibles.
CR20170510A (es) 2015-04-10 2018-02-26 Amgen Inc Muteínas de interuquina 2 para la expansión de células t regulatorias
CN116063543A (zh) 2015-04-24 2023-05-05 豪夫迈·罗氏有限公司 多特异性抗原结合蛋白
US11591382B2 (en) 2015-09-22 2023-02-28 Genentech, Inc. Expression of Fc-containing proteins
CN116396393A (zh) 2015-10-08 2023-07-07 酵活英属哥伦比亚省公司 包含κ和λ轻链的抗原结合多肽构建体及其用途
CN105331630A (zh) * 2015-10-29 2016-02-17 中国农业大学 一种增强玉米外源基因表达的方法
EP3371206B1 (en) 2015-11-02 2021-04-14 F. Hoffmann-La Roche AG Methods of making fucosylated and afucosylated forms of a protein
KR20240115933A (ko) 2016-05-04 2024-07-26 암젠 인크 T-조절 세포의 증식을 위한 인터류킨-2 뮤테인
ES2873723T3 (es) * 2016-07-22 2021-11-03 Univ Oregon Health & Science Colecciones de genoma completo de células individuales y métodos de indexación combinatoria para prepararlas
JP7234146B2 (ja) 2018-05-17 2023-03-07 イルミナ インコーポレイテッド 低減した増幅バイアスによるハイスループット単一細胞シークエンシング
MX2022001866A (es) 2019-08-13 2022-03-11 Amgen Inc Muteinas de interleucina-2 para la expansion de celulas t reguladoras.
WO2021127262A1 (en) 2019-12-17 2021-06-24 Amgen Inc. Dual interleukin-2 /tnf receptor agonist for use in therapy
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
IL301396A (en) 2020-09-30 2023-05-01 Nobell Foods Inc Recombinant milk proteins and food compositions comprising the same
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
AU2024307352A1 (en) 2023-06-27 2025-12-11 Amgen Inc. Charge pair mutations to enable correct heavy-light chain pairing

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2176208T3 (es) 1992-10-05 2002-12-01 Univ North Carolina State Metodo para incrementar la expresion y para reducir la variabilidad de expresion de genes foraneos en celulas vegetales.
US6040185A (en) * 1993-04-19 2000-03-21 Novartis Ag Genetic stabilizing elements
US5773695A (en) 1996-01-26 1998-06-30 North Carolina State University Plant nuclear scaffold attachment region and method for increasing gene expression in transgenic cells

Also Published As

Publication number Publication date
US20020073448A1 (en) 2002-06-13
US6245974B1 (en) 2001-06-12
WO1999007866A1 (en) 1999-02-18
AR013400A1 (es) 2000-12-27
JP2001520861A (ja) 2001-11-06
AU749014B2 (en) 2002-06-13
AU8693698A (en) 1999-03-01
CA2298052A1 (en) 1999-02-18
EP1005560A1 (en) 2000-06-07

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007.