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BR9810917A - Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador - Google Patents

Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador

Info

Publication number
BR9810917A
BR9810917A BR9810917-0A BR9810917A BR9810917A BR 9810917 A BR9810917 A BR 9810917A BR 9810917 A BR9810917 A BR 9810917A BR 9810917 A BR9810917 A BR 9810917A
Authority
BR
Brazil
Prior art keywords
polypeptide
isolated
antibody
pharmaceutical composition
produce
Prior art date
Application number
BR9810917-0A
Other languages
English (en)
Inventor
Paul O Sheppard
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of BR9810917A publication Critical patent/BR9810917A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"POLIPEPTìDEO ISOLADO, PROTEìNA DE FUSãO, VETOR DE EXPRESSãO, CéLULA CULTIVADA, PROCESSO PARA PRODUZIR UM POLIPEPTìDEO, COMPOSIçãO FARMACêUTICA, ANTICORPO, PROTEìNA DE LIGAçãO, POLINUCLEOTìDEO ISOLADO, E, SONDA DE OLIGONUCLEOTìDEO OU INICIADOR". A presente invenção refere-se a moléculas de polinucleotídeo e polipeptídeo para zsig37, um membro da família de proteínas contendo um domínio semelhante a colágeno e um domínio globular. Os polipeptídeos, e polinucleotídeos codificando os mesmos, são envolvidos na dimerização ou oligomerização e podem ser usados no estudo dos mesmos. A presente invenção também inclui anticorpos para os polipeptídeos zsig37.
BR9810917-0A 1997-07-18 1998-07-17 Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador BR9810917A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5315497P 1997-07-18 1997-07-18
PCT/US1998/014864 WO1999004000A1 (en) 1997-07-18 1998-07-17 Adipocyte-specific protein homologs

Publications (1)

Publication Number Publication Date
BR9810917A true BR9810917A (pt) 2000-08-15

Family

ID=21982287

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9810917-0A BR9810917A (pt) 1997-07-18 1998-07-17 Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador

Country Status (18)

Country Link
US (2) US6265544B1 (pt)
EP (1) EP1002075B1 (pt)
JP (1) JP3762220B2 (pt)
KR (1) KR100385868B1 (pt)
CN (1) CN1201003C (pt)
AT (1) ATE327328T1 (pt)
AU (1) AU743745B2 (pt)
BR (1) BR9810917A (pt)
CA (1) CA2296530A1 (pt)
DE (1) DE69834643T2 (pt)
DK (1) DK1002075T3 (pt)
ES (1) ES2264207T3 (pt)
HU (1) HUP0003762A3 (pt)
IL (1) IL134011A0 (pt)
NO (1) NO20000215L (pt)
PL (1) PL338139A1 (pt)
RU (1) RU2218402C2 (pt)
WO (1) WO1999004000A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2296530A1 (en) * 1997-07-18 1999-01-28 Zymogenetics, Inc. Adipocyte-specific protein homologs
US6566499B1 (en) * 1997-07-18 2003-05-20 Zymogenetics, Inc. Adipocyte-specific protein homologs
FR2767135B1 (fr) 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
US20030129691A1 (en) * 1998-02-09 2003-07-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7300774B1 (en) 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
AU772103B2 (en) * 1999-02-19 2004-04-08 Zymogenetics Inc. Inhibitors for use in hemostasis and immune function
US20040014650A1 (en) * 2002-07-17 2004-01-22 Sheppard Paul D Methods for enhancing wound repair
US6544946B1 (en) 1999-02-19 2003-04-08 Zymogenetics, Inc. Inhibitors for use in hemostasis and immune function
US20050042719A1 (en) * 1999-05-27 2005-02-24 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
JP2003501027A (ja) * 1999-05-27 2003-01-14 ザイモジェネティクス，インコーポレイティド 脂肪細胞補体関連タンパク質同族体ｚａｃｒｐ５
WO2000073446A2 (en) * 1999-05-27 2000-12-07 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp6
EP1953173B1 (en) * 1999-06-15 2009-11-18 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids endoding the same
CA2378951A1 (en) * 1999-07-01 2001-01-11 Zymogenetics, Inc. Secreted protein zacrp4
DE19963859A1 (de) * 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
AU2001297656A1 (en) * 2000-11-29 2002-09-19 Zymogenetics, Inc. Adipocyte complement related protein zacrp11
IL156864A0 (en) 2001-01-16 2004-02-08 Genset Sa Polynucleotides and polypeptides and their use in metabolic disorders
EP1421190A2 (en) 2001-01-16 2004-05-26 Genset Metabolic gene polynucleotides and polypeptides and uses thereof
US20030220253A1 (en) * 2002-03-08 2003-11-27 Lasser Gerald W. Inhibitors for use in hemostasis
US20050266464A1 (en) * 2004-05-21 2005-12-01 Xencor, Inc. C1q family member proteins with altered immunogenicity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8116494A (en) 1993-11-12 1995-06-13 Kenichi Matsubara Gene signature
US5869330A (en) 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
CA2296530A1 (en) * 1997-07-18 1999-01-28 Zymogenetics, Inc. Adipocyte-specific protein homologs
NZ504548A (en) * 1997-12-03 2003-06-30 Genentech Inc Polypeptides and nucleic acids encoding human chordin

Also Published As

Publication number Publication date
JP2001510045A (ja) 2001-07-31
DE69834643T2 (de) 2007-05-10
CN1272883A (zh) 2000-11-08
CN1201003C (zh) 2005-05-11
US20020156243A1 (en) 2002-10-24
EP1002075A1 (en) 2000-05-24
KR100385868B1 (ko) 2003-06-02
KR20010021973A (ko) 2001-03-15
AU743745B2 (en) 2002-02-07
US6265544B1 (en) 2001-07-24
DK1002075T3 (da) 2006-09-18
NO20000215L (no) 2000-03-17
JP3762220B2 (ja) 2006-04-05
EP1002075B1 (en) 2006-05-24
PL338139A1 (en) 2000-09-25
ES2264207T3 (es) 2006-12-16
DE69834643D1 (de) 2006-06-29
WO1999004000A1 (en) 1999-01-28
NO20000215D0 (no) 2000-01-17
CA2296530A1 (en) 1999-01-28
IL134011A0 (en) 2001-04-30
ATE327328T1 (de) 2006-06-15
US6518403B2 (en) 2003-02-11
RU2218402C2 (ru) 2003-12-10
AU8411398A (en) 1999-02-10
HUP0003762A3 (en) 2005-11-28
HUP0003762A2 (hu) 2001-08-28

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Legal Events

Date Code Title Description
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART 36 DA LPI (LEI 9.279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR.