BR9810046A - Nucleotide sequence, expression vector, host cell, mammalian sperm protein, recombinant sperm protein, sperm protein 4, 1 and / or 6.7, pharmaceutical composition, and contraceptive vaccine - Google Patents
Nucleotide sequence, expression vector, host cell, mammalian sperm protein, recombinant sperm protein, sperm protein 4, 1 and / or 6.7, pharmaceutical composition, and contraceptive vaccineInfo
- Publication number
- BR9810046A BR9810046A BR9810046-7A BR9810046A BR9810046A BR 9810046 A BR9810046 A BR 9810046A BR 9810046 A BR9810046 A BR 9810046A BR 9810046 A BR9810046 A BR 9810046A
- Authority
- BR
- Brazil
- Prior art keywords
- sperm protein
- mammalian
- host cell
- expression vector
- nucleotide sequence
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 229940124462 contraceptive vaccine Drugs 0.000 title abstract 2
- 239000013604 expression vector Substances 0.000 title abstract 2
- 239000002773 nucleotide Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 229960005486 vaccine Drugs 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"SEQUêNCIA DE NUCLEOTìDEOS, VETOR DE EXPRESSãO, CéLULA HOSPEDEIRA, PROTEìNA DE ESPERMA DE MAMìFERO, E, VACINA CONTRACEPTIVA" A presente invenção refere-se a proteínas 4,1 e 6,7 específicas de mamífero, e sequências de nucleotídeos codificando referidas proteínas, bem como formulações farmacêuticas, em particular vacinas compreendendo referidas proteínas. As proteínas 4,1 e 6,7 são específicas de esperma e podem ser usadas em uma vacina para evitar ou reduzir fertilidade em indivíduos."NUCLEOTIDE SEQUENCE, EXPRESSION VECTOR, HOST CELL, MAMMALIAN SPERM PROTEIN, AND, CONTRACEPTIVE VACCINE" The present invention relates to mammalian-specific 4.1 and 6.7 proteins, and nucleotide sequences encoding said proteins, as well as pharmaceutical formulations, in particular vaccines comprising said proteins. Proteins 4.1 and 6.7 are sperm specific and can be used in a vaccine to prevent or reduce fertility in individuals.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201863 | 1997-06-19 | ||
| PCT/EP1998/004016 WO1998058954A2 (en) | 1997-06-19 | 1998-06-17 | Sperm specific antigens 4.1 and 6.7, dna encoding them and contraceptive vaccines comprising said sperm antigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9810046A true BR9810046A (en) | 2000-08-29 |
Family
ID=8228457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9810046-7A BR9810046A (en) | 1997-06-19 | 1998-06-17 | Nucleotide sequence, expression vector, host cell, mammalian sperm protein, recombinant sperm protein, sperm protein 4, 1 and / or 6.7, pharmaceutical composition, and contraceptive vaccine |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1012176A1 (en) |
| JP (1) | JP2002505583A (en) |
| AU (1) | AU8339898A (en) |
| BR (1) | BR9810046A (en) |
| CA (1) | CA2296002A1 (en) |
| WO (1) | WO1998058954A2 (en) |
-
1998
- 1998-06-17 WO PCT/EP1998/004016 patent/WO1998058954A2/en not_active Ceased
- 1998-06-17 CA CA002296002A patent/CA2296002A1/en not_active Abandoned
- 1998-06-17 BR BR9810046-7A patent/BR9810046A/en not_active Application Discontinuation
- 1998-06-17 EP EP98933652A patent/EP1012176A1/en not_active Withdrawn
- 1998-06-17 JP JP50381899A patent/JP2002505583A/en active Pending
- 1998-06-17 AU AU83398/98A patent/AU8339898A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998058954A2 (en) | 1998-12-30 |
| WO1998058954A3 (en) | 1999-03-18 |
| AU8339898A (en) | 1999-01-04 |
| EP1012176A1 (en) | 2000-06-28 |
| JP2002505583A (en) | 2002-02-19 |
| CA2296002A1 (en) | 1998-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |