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BR9808192A - Processo de clonagem de animais - Google Patents

Processo de clonagem de animais

Info

Publication number
BR9808192A
BR9808192A BR9808192-6A BR9808192A BR9808192A BR 9808192 A BR9808192 A BR 9808192A BR 9808192 A BR9808192 A BR 9808192A BR 9808192 A BR9808192 A BR 9808192A
Authority
BR
Brazil
Prior art keywords
cells
animals
embryos
cloning process
cloning
Prior art date
Application number
BR9808192-6A
Other languages
English (en)
Inventor
Nikolai S Strelchenko
Jeffery M Betthauser
Gail L Jurgeella
Marvin M Pace
Michael D Bishop
Original Assignee
Infigen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infigen Inc filed Critical Infigen Inc
Publication of BR9808192A publication Critical patent/BR9808192A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fertilizers (AREA)
  • Steroid Compounds (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO DE CLONAGEM DE ANIMAIS"<D>. A presente invenção refere-se a tecnologias de clonagem. A invenção refere-se em parte a células imortalizadas e totipotente úteis para clonagem de animais, aos embriões produzidos a partir destas células usando-se técnicas de transferência nuclear, aos animais que surgem a partir destas células e aos embriões, aos materiais, aos métodos e aos processos para criação de tais células, embriões e animais.
BR9808192-6A 1997-03-06 1998-03-05 Processo de clonagem de animais BR9808192A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81285197A 1997-03-06 1997-03-06
US81203197A 1997-03-06 1997-03-06
US7301998P 1998-01-29 1998-01-29
PCT/US1998/004345 WO1998039416A1 (en) 1997-03-06 1998-03-05 Method of cloning animals

Publications (1)

Publication Number Publication Date
BR9808192A true BR9808192A (pt) 2000-10-24

Family

ID=27372211

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808192-6A BR9808192A (pt) 1997-03-06 1998-03-05 Processo de clonagem de animais

Country Status (7)

Country Link
EP (1) EP0973871A1 (pt)
JP (1) JP2002512510A (pt)
AU (1) AU745334B2 (pt)
BR (1) BR9808192A (pt)
CA (1) CA2282722A1 (pt)
NZ (1) NZ337495A (pt)
WO (1) WO1998039416A1 (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331659B1 (en) * 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
WO1999045100A1 (en) * 1998-03-02 1999-09-10 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Embryonic or stem-like cell lines produced by cross-species nuclear transplantation
US6700037B2 (en) * 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
US6258998B1 (en) * 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
AU780809B2 (en) * 1999-01-13 2005-04-21 Revivicor Inc Double nuclear transfer method and results thereof
JP2002537785A (ja) * 1999-03-04 2002-11-12 ピーピーエル セラピューティクス （スコットランド） リミテッド 体細胞の遺伝的改変とそれらの使用
AU4389699A (en) * 1999-06-04 2000-12-28 Istituto Zootecnico E Caseario Per La Sardegna Process for reconstructing a non-human animal embryo by nuclear transfer and preparing the animal therefrom, and embryos and animals obtained thereby
RU2205536C2 (ru) * 1999-06-30 2003-06-10 Воо-Сук ХВАНГ Способ получения клонированной коровы
EP1117763A4 (en) * 1999-06-30 2004-12-01 Hwang Woo Suk PROCESS FOR PRODUCING CLONED TIGERS USING INTER-SPECIES CORE TRANSPLANTATION TECHNIQUE
IL148457A0 (en) * 1999-09-07 2002-09-12 Advanced Cell Tech Inc Telomere restoration and extension of cell life-span in animals cloned from senescent somatic cells
US7074983B2 (en) 1999-11-19 2006-07-11 Kirin Beer Kabushiki Kaisha Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin
US7414170B2 (en) 1999-11-19 2008-08-19 Kirin Beer Kabushiki Kaisha Transgenic bovines capable of human antibody production
US6906238B2 (en) 2000-03-15 2005-06-14 University Of Georgia Research Foundation, Inc. Effective nuclear reprogramming in mammals using CDK2 inhibitors
WO2002009510A2 (en) * 2000-08-01 2002-02-07 Xy Genetics, Llc Methods of selecting and cloning animals
WO2002045490A2 (en) * 2000-12-05 2002-06-13 Université de Montréal Method of cloning animals
US7491534B2 (en) 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
MXPA03005624A (es) 2000-12-22 2004-12-03 Vaurox Llc Metodos para clonar mamiferos usando cromatina reprogramada del donador o celulas donadoras.
US7309811B2 (en) 2001-02-23 2007-12-18 Elan Pharmaceuticals, Inc Transgenic mice knockouts of BACE-1
WO2002074935A2 (en) * 2001-03-21 2002-09-26 Geron Corporation Use of telomerase reverse transcriptase to create homozygous knockout animals
NZ536303A (en) * 2002-04-24 2008-04-30 Univ Georgia Res Found Production of cloned offspring from cooled carcasses
CN100480260C (zh) 2002-07-18 2009-04-22 克鲁塞尔荷兰公司 抗体混合物的重组生产
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
CA2502490A1 (en) 2002-11-08 2004-05-27 Hematech, Llc Transgenic ungulates having reduced prion protein activity and uses thereof
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
CA2527694C (en) 2003-05-30 2015-07-14 Hendricus Renerus Jacobus Mattheus Hoogenboom Fab library for the preparation of anti vegf and anti rabies virus fabs
DK1737971T3 (da) 2004-01-20 2017-11-13 Merus Nv Blandinger af bindingsproteiner
NZ550106A (en) 2004-04-22 2009-06-26 Kyowa Hakko Kirin Co Ltd Transgenic animals and uses thereof
JP2006081542A (ja) * 2004-08-18 2006-03-30 Institute Of Physical & Chemical Research クローン哺乳動物の作成方法
US8796021B2 (en) 2007-02-23 2014-08-05 Advanced Cell Technology, Inc. Blastomere culture to produce mammalian embryonic stem cells
EP2987498B1 (en) 2008-05-02 2017-07-05 Laboratoire Français du Fractionnement et des Biotechnologies Treatment of bleeding with low half-life fibrinogen
US20130045492A1 (en) 2010-02-08 2013-02-21 Regeneron Pharmaceuticals, Inc. Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
PL2501817T5 (pl) 2010-02-08 2021-08-16 Regeneron Pharmaceuticals, Inc. Mysz o wspólnym łańcuchu lekkim
US9796788B2 (en) 2010-02-08 2017-10-24 Regeneron Pharmaceuticals, Inc. Mice expressing a limited immunoglobulin light chain repertoire
EP2603581B1 (en) 2010-08-11 2019-07-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Cocultures of cumulus cells and embryos during in vitro fertilization procedures
WO2012122512A1 (en) 2011-03-10 2012-09-13 Hco Antibody, Inc. Recombinant production of mixtures of single chain antibodies
SMT202100357T1 (it) 2011-08-05 2021-07-12 Regeneron Pharma Topi di catena leggera universale umanizzata
WO2013157953A1 (en) 2012-04-20 2013-10-24 Merus B.V. Methods and means for the production of ig-like molecules
CA3124228C (en) 2014-03-21 2024-05-14 Regeneron Pharmaceuticals, Inc. Non-human animals that make single domain binding proteins
JP2018508224A (ja) 2015-03-19 2018-03-29 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 抗原を結合する軽鎖可変領域を選択する非ヒト動物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0380646B1 (en) * 1988-08-04 1999-01-20 Amrad Corporation Limited Use of leukaemia inhibitory factor (lif) for the (in vitro) propagation of embryonic stem cells
JP2988753B2 (ja) * 1990-08-29 1999-12-13 科学技術振興事業団 不死化細胞株の樹立方法とその細胞株
WO1994007997A1 (en) * 1992-10-06 1994-04-14 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Long-term proliferation of primordial germ cells
US5453357A (en) * 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
AU1439295A (en) * 1993-12-17 1995-07-03 Abs Global, Inc. Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates
GB9417831D0 (en) * 1994-09-05 1994-10-26 Biotech & Biolog Scien Res Biological manipulation
FR2726003B1 (fr) * 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
AU1274797A (en) * 1995-11-29 1997-06-19 Utah State University Establishment, maintenance, and transfection of totipotent embryonic stem cells from the embryos of domestic animals
AU721375B2 (en) * 1996-01-09 2000-06-29 Regents Of The University Of California, The Porcine embryonic stem-like cells, methods of making and using the cells to produce transgenic pigs
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
AU711190B2 (en) * 1997-03-14 1999-10-07 Cselt-Centro Studi E Laboratori Telecomunicazioni S.P.A. Circuit for motion estimation in digitised video sequence encoders

Also Published As

Publication number Publication date
EP0973871A1 (en) 2000-01-26
CA2282722A1 (en) 1998-09-11
AU745334B2 (en) 2002-03-21
NZ337495A (en) 2001-06-29
AU6688098A (en) 1998-09-22
JP2002512510A (ja) 2002-04-23
WO1998039416A1 (en) 1998-09-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1937 DE 19/02/2008

B15K Others concerning applications: alteration of classification

Ipc: C12N 15/877 (2010.01), C12N 5/0735 (2010.0