BR9807009A - Composition for administration of steroid drug transfer - Google Patents
Composition for administration of steroid drug transferInfo
- Publication number
- BR9807009A BR9807009A BR9807009-6A BR9807009A BR9807009A BR 9807009 A BR9807009 A BR 9807009A BR 9807009 A BR9807009 A BR 9807009A BR 9807009 A BR9807009 A BR 9807009A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- administration
- steroid drug
- drug transfer
- steroid
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title abstract 3
- 150000003431 steroids Chemical class 0.000 title abstract 3
- 229940124532 absorption promoter Drugs 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- -1 sorbitan ester Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
"COMPOSIçãO PARA ADMINISTRAçãO TRANSDéRMICA DE MEDICAMENTOS ESTERóIDES". Composição para administração transdérmica de um medicamento esteróide contendo uma quantidade terapeuticamente eficaz de um medicamento; um promotor de absorção consistindo essencialmente de éter dietileno glico e um éster sorbitan e uma matriz adesiva famaceuticamente aceitável."COMPOSITION FOR TRANSDERMAL ADMINISTRATION OF STEROID MEDICINES". Composition for transdermal administration of a steroid drug containing a therapeutically effective amount of a drug; an absorption promoter consisting essentially of diethylene glycol ether and a sorbitan ester and a pharmaceutically acceptable adhesive matrix.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019970002233A KR100215027B1 (en) | 1997-01-27 | 1997-01-27 | Composition for transdermal administration of steroid drugs and formulation containing same |
| PCT/KR1998/000013 WO1998032465A1 (en) | 1997-01-27 | 1998-01-23 | Composition for the transdermal administration of steroid drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9807009A true BR9807009A (en) | 2000-03-14 |
Family
ID=19495561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9807009-6A BR9807009A (en) | 1997-01-27 | 1998-01-23 | Composition for administration of steroid drug transfer |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1001812A1 (en) |
| JP (1) | JP2000508349A (en) |
| KR (1) | KR100215027B1 (en) |
| CN (1) | CN1244806A (en) |
| AR (1) | AR011577A1 (en) |
| AU (1) | AU727811B2 (en) |
| BR (1) | BR9807009A (en) |
| CA (1) | CA2277970A1 (en) |
| ID (1) | ID19755A (en) |
| RU (1) | RU2176499C2 (en) |
| TW (1) | TW537899B (en) |
| WO (1) | WO1998032465A1 (en) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100294084B1 (en) * | 1998-06-02 | 2001-09-22 | 성재갑 | Composition for transdermal administration of non-steroid drugs and formulation containing same |
| AU2223600A (en) * | 1999-01-06 | 2000-07-24 | Cedars-Sinai Medical Center | Hormone replacement for breast cancer patients |
| KR100403051B1 (en) * | 2000-07-25 | 2003-10-23 | 일양약품주식회사 | Composition of matrix type patch for transdermal testosterone delivery and process for preparing the same |
| US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| DE10107663B4 (en) * | 2001-02-19 | 2004-09-09 | Lts Lohmann Therapie-Systeme Ag | Testosterone-containing transdermal therapeutic system, process for its preparation and its use |
| DE10163459A1 (en) * | 2001-12-21 | 2003-07-03 | Merck Patent Gmbh | Lyophilized preparation containing antibodies to EGF receptor |
| FR2848112B1 (en) * | 2002-12-10 | 2007-02-16 | Besins Int Belgique | PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL OR TRANSMUCTIVE DELIVERY COMPRISING AT LEAST ONE PROGESTATIVE AND / OR AT LEAST ONE OESTROGEN, PREPARATION METHOD AND USES THEREOF |
| AU2003296810A1 (en) * | 2002-12-10 | 2004-07-09 | Besins International Belgique | Pharmaceutical composition for transdermal or transmucous administration comprising a progestin or an estrogen, method for preparing same and uses thereof |
| FR2851470B1 (en) | 2003-02-20 | 2007-11-16 | Besins Int Belgique | PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL OR TRANSMUCTIVE DELIVERY |
| JP4422430B2 (en) * | 2003-05-14 | 2010-02-24 | 帝國製薬株式会社 | External patch containing estrogen and / or progestogen |
| GB0409498D0 (en) * | 2004-04-28 | 2004-06-02 | Hunter Fleming Ltd | Transdermal steroid formulation |
| CN1313084C (en) * | 2004-11-05 | 2007-05-02 | 郑会义 | Percutaneous contraceptive drugs delivery system and method |
| DE102004059880A1 (en) * | 2004-12-10 | 2006-06-14 | Grünenthal GmbH | Stable, hormone-containing (intermediate) product |
| JP4969050B2 (en) * | 2005-01-07 | 2012-07-04 | ロート製薬株式会社 | Topical skin preparation |
| JP2007045808A (en) * | 2005-01-07 | 2007-02-22 | Rohto Pharmaceut Co Ltd | Skin care preparation |
| US10080760B2 (en) | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
| JP6004364B2 (en) * | 2011-10-14 | 2016-10-05 | 大正製薬株式会社 | Topical skin preparation |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| EP3936133A1 (en) | 2011-11-23 | 2022-01-12 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| JP5521025B2 (en) * | 2012-12-21 | 2014-06-11 | 日本精化株式会社 | Penetration enhancer |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10206932B2 (en) | 2014-05-22 | 2019-02-19 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| CA3020153A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| KR101968873B1 (en) * | 2018-09-21 | 2019-04-29 | 아이큐어 주식회사 | Cosmetic composition comprising peptide derived from Botulinum toxin having improved cell penetrating ability |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4291015A (en) * | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
| JPH0744940B2 (en) * | 1986-12-24 | 1995-05-17 | ライオン株式会社 | Base material for oral application |
| CH674618A5 (en) * | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
| CA1333114C (en) * | 1987-11-25 | 1994-11-15 | Daniel C. Duan | Pressure-sensitive adhesives and bioelectrodes constructed with the adhesive |
| US4906475A (en) * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
| ATE132751T1 (en) * | 1988-10-27 | 1996-01-15 | Schering Ag | AGENTS FOR TRANSDERMAL APPLICATION CONTAINING STODENE |
| DE3910578A1 (en) * | 1989-03-29 | 1990-10-04 | Schering Ag | Composition for transdermal administration containing gestodene |
| US4973468A (en) * | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
| ATE107517T1 (en) * | 1989-05-25 | 1994-07-15 | Takeda Chemical Industries Ltd | TRANSDERMAL THERAPEUTIC AGENT. |
| US5314685A (en) * | 1992-05-11 | 1994-05-24 | Agouron Pharmaceuticals, Inc. | Anhydrous formulations for administering lipophilic agents |
-
1997
- 1997-01-27 KR KR1019970002233A patent/KR100215027B1/en not_active Expired - Fee Related
-
1998
- 1998-01-23 BR BR9807009-6A patent/BR9807009A/en not_active Application Discontinuation
- 1998-01-23 JP JP10531848A patent/JP2000508349A/en active Pending
- 1998-01-23 CA CA002277970A patent/CA2277970A1/en not_active Abandoned
- 1998-01-23 AU AU58820/98A patent/AU727811B2/en not_active Ceased
- 1998-01-23 CN CN98802010A patent/CN1244806A/en active Pending
- 1998-01-23 WO PCT/KR1998/000013 patent/WO1998032465A1/en not_active Ceased
- 1998-01-23 EP EP98902269A patent/EP1001812A1/en not_active Withdrawn
- 1998-01-23 RU RU99118582/14A patent/RU2176499C2/en not_active IP Right Cessation
- 1998-01-26 TW TW087101089A patent/TW537899B/en active
- 1998-01-27 AR ARP980100352A patent/AR011577A1/en not_active Application Discontinuation
- 1998-01-27 ID IDP980113A patent/ID19755A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR011577A1 (en) | 2000-08-30 |
| CA2277970A1 (en) | 1998-07-30 |
| KR100215027B1 (en) | 1999-08-16 |
| CN1244806A (en) | 2000-02-16 |
| JP2000508349A (en) | 2000-07-04 |
| AU5882098A (en) | 1998-08-18 |
| TW537899B (en) | 2003-06-21 |
| ID19755A (en) | 1998-07-30 |
| EP1001812A1 (en) | 2000-05-24 |
| RU2176499C2 (en) | 2001-12-10 |
| WO1998032465A1 (en) | 1998-07-30 |
| AU727811B2 (en) | 2000-12-21 |
| KR19980066583A (en) | 1998-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |