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BR9714401A - Antìgenos de supefìcie de célula de mamìfero; regentes relacionados - Google Patents

Antìgenos de supefìcie de célula de mamìfero; regentes relacionados

Info

Publication number
BR9714401A
BR9714401A BR9714401-0A BR9714401A BR9714401A BR 9714401 A BR9714401 A BR 9714401A BR 9714401 A BR9714401 A BR 9714401A BR 9714401 A BR9714401 A BR 9714401A
Authority
BR
Brazil
Prior art keywords
cell surface
rulers
mammalian cell
surface antigens
reagents
Prior art date
Application number
BR9714401-0A
Other languages
English (en)
Inventor
Daniel M Gorman
Jeanine D Mattson
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21867133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9714401(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of BR9714401A publication Critical patent/BR9714401A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Patente de Invenção: <B>"ANTìGENOS DE SUPERFìCIE DE CéLULAS DE MAMìFERO; REAGENTES RELACIONADOS"<D>. Genes purificados codificando um antígeno de superfície de célula T de um mamífero, reagentes relacionados a eles incluindo proteínas purificadas, anticorpos específicos e ácidos nucléicos codificados este antígeno são providos. Métodos de uso dos ditos reagentes e kits de diagnóstico são providos.
BR9714401-0A 1996-12-13 1997-12-12 Antìgenos de supefìcie de célula de mamìfero; regentes relacionados BR9714401A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3284696P 1996-12-13 1996-12-13
PCT/US1997/022766 WO1998025958A2 (en) 1996-12-13 1997-12-12 Mammalian cell surface antigens comprising structural motifs characteristic of a member of the tnf ligand family

Publications (1)

Publication Number Publication Date
BR9714401A true BR9714401A (pt) 2000-04-18

Family

ID=21867133

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9714401-0A BR9714401A (pt) 1996-12-13 1997-12-12 Antìgenos de supefìcie de célula de mamìfero; regentes relacionados

Country Status (14)

Country Link
US (5) US6242586B1 (pt)
EP (5) EP1995317B1 (pt)
JP (6) JP2001506991A (pt)
CN (1) CN1245534A (pt)
AT (1) ATE399861T1 (pt)
AU (1) AU5697098A (pt)
BR (1) BR9714401A (pt)
CA (1) CA2274801C (pt)
DE (2) DE122010000046I1 (pt)
DK (1) DK1114864T4 (pt)
ES (1) ES2305009T5 (pt)
LU (1) LU91756I2 (pt)
PT (1) PT1114864E (pt)
WO (1) WO1998025958A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117175A (en) * 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US7632922B1 (en) * 1995-12-22 2009-12-15 Amgen, Inc. Osteoprotegerin
ES2305009T5 (es) * 1996-12-13 2012-11-15 Merck Sharp & Dohme Corp. Antígenos de superficie de células de mamíferos; reactivos relacionados
ES2144386T5 (es) * 1996-12-23 2012-12-07 Immunex Corporation Ligando para el activador del receptor de NF-kappa b, el ligando es miembro de la superfamilia de TNF
US6271349B1 (en) 1996-12-23 2001-08-07 Immunex Corporation Receptor activator of NF-κB
WO1999058674A2 (en) * 1998-05-14 1999-11-18 Immunex Corporation Method of inhibiting osteoclast activity
AU2008200700C1 (en) * 1997-04-15 2013-04-04 Daiichi Sankyo Co., Ltd Novel Protein and Process for Producing The Same
NZ332995A (en) * 1997-04-15 2000-07-28 Snow Brand Milk Products Co Ltd A protein which binds to osteoclastogenesis inhibitory factor (OCIF)
AU2011202547B2 (en) * 1997-04-16 2014-08-28 Amgen Inc. Osteoprotegerin binding proteins and receptors
US5843678A (en) * 1997-04-16 1998-12-01 Amgen Inc. Osteoprotegerin binding proteins
NZ500253A (en) * 1997-04-16 2002-09-27 Amgen Inc Osteoprotegerin binding proteins and receptors
US6316408B1 (en) * 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
US6084926A (en) * 1997-12-08 2000-07-04 Ericsson Inc. Method and system for demodulating radio signals
US7063960B2 (en) 1997-12-12 2006-06-20 The Rockefeller University Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof
HK1040261A1 (zh) 1998-09-15 2002-05-31 法麦克萨有限公司 负调节osteoprotegerin配体活性的方法
EP1541587A3 (en) * 1998-09-15 2007-06-20 Pharmexa A/S Method for down-regulating osteoprotegerin ligand activity
CA2400929C (en) † 2000-02-23 2011-05-31 Amgen Inc. Antagonistic selective binding agents of osteoprotegerin binding protein
US20030103978A1 (en) * 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
EP1368464B1 (en) * 2000-09-22 2007-07-04 Immunex Corporation Screening assays for agonists or antagonists of receptor activator of nf-kb
US7128911B2 (en) * 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
EP3492100B1 (en) 2001-06-26 2021-12-08 Amgen Inc. Antibodies to opgl
CA2481074A1 (en) * 2002-04-05 2003-10-23 Amgen Inc. Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors
CA2508773C (en) * 2002-12-10 2013-08-27 Schering-Plough Ltd. Canine rankl and methods for preparing and using the same
CA2608003A1 (en) * 2004-06-02 2005-12-15 Cytos Biotechnology Ag Medical uses of carrier conjugates of non-human tnf-peptides
US7582910B2 (en) * 2005-02-28 2009-09-01 The Regents Of The University Of California High efficiency light emitting diode (LED) with optimized photonic crystal extractor

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2046920B1 (pt) 1969-06-19 1974-05-03 Citizen Watch Co Ltd
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
DE3382317D1 (de) 1982-03-15 1991-07-25 Schering Corp Hybride dns, damit hergestellte bindungszusammensetzung und verfahren dafuer.
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
EP0630405B1 (en) 1992-11-17 1998-04-08 Icos Corporation Novel V28 seven transmembrane receptor
IL117175A (en) * 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
EP0833941B1 (en) * 1995-04-07 2008-10-22 Cytogen Corporation Polypeptides having a functional domain of interest and methods of identifying and using same
US6613544B1 (en) 1995-12-22 2003-09-02 Amgen Inc. Osteoprotegerin
US6111090A (en) * 1996-08-16 2000-08-29 Schering Corporation Mammalian cell surface antigens; related reagents
ES2305009T5 (es) * 1996-12-13 2012-11-15 Merck Sharp & Dohme Corp. Antígenos de superficie de células de mamíferos; reactivos relacionados
US6271349B1 (en) * 1996-12-23 2001-08-07 Immunex Corporation Receptor activator of NF-κB
ES2144386T5 (es) * 1996-12-23 2012-12-07 Immunex Corporation Ligando para el activador del receptor de NF-kappa b, el ligando es miembro de la superfamilia de TNF
WO1999058674A2 (en) * 1998-05-14 1999-11-18 Immunex Corporation Method of inhibiting osteoclast activity
NZ332995A (en) 1997-04-15 2000-07-28 Snow Brand Milk Products Co Ltd A protein which binds to osteoclastogenesis inhibitory factor (OCIF)
US6316408B1 (en) * 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
NZ500253A (en) * 1997-04-16 2002-09-27 Amgen Inc Osteoprotegerin binding proteins and receptors
US5843678A (en) * 1997-04-16 1998-12-01 Amgen Inc. Osteoprotegerin binding proteins

Also Published As

Publication number Publication date
US20090092597A1 (en) 2009-04-09
EP1995317B1 (en) 2014-11-05
EP1114864B2 (en) 2012-07-25
JP2001506991A (ja) 2001-05-29
EP1803816A3 (en) 2007-09-26
ATE399861T1 (de) 2008-07-15
JP2010172336A (ja) 2010-08-12
EP1803816A2 (en) 2007-07-04
DK1114864T4 (da) 2012-09-03
HK1034743A1 (en) 2001-11-02
EP1114864A2 (en) 2001-07-11
WO1998025958A3 (en) 1998-07-30
EP1995317A1 (en) 2008-11-26
JP2009254381A (ja) 2009-11-05
DE69738811D1 (de) 2008-08-14
CA2274801C (en) 2014-02-04
EP1114864B9 (en) 2013-05-08
CN1245534A (zh) 2000-02-23
PT1114864E (pt) 2008-10-08
JP2010119397A (ja) 2010-06-03
ES2305009T3 (es) 2008-11-01
US6525180B1 (en) 2003-02-25
JP2013074899A (ja) 2013-04-25
LU91756I2 (fr) 2011-01-24
EP0948530A2 (en) 1999-10-13
US20030144480A1 (en) 2003-07-31
DE122010000046I1 (de) 2011-05-05
EP1114864B1 (en) 2008-07-02
JP2008143906A (ja) 2008-06-26
US20060025572A1 (en) 2006-02-02
EP1995318A1 (en) 2008-11-26
ES2305009T5 (es) 2012-11-15
WO1998025958A2 (en) 1998-06-18
US6242586B1 (en) 2001-06-05
US7063841B2 (en) 2006-06-20
AU5697098A (en) 1998-07-03
EP1114864A3 (en) 2001-10-10
CA2274801A1 (en) 1998-06-18
DK1114864T3 (da) 2008-10-06

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: A REQUERENTE APRESENTOU NOVO QUADRO REIVINDICATORIO COMPOSTO POR 24 (VINTE E QUATRO) REIVINDICACOES. ENTRETANTO, NAO APRESENTOU COMPROVACAO DA COMPLEMENTACAO DE RETRIBUICAO DEVIDA PELO EXAME DE 11 (ONZE) REIVINDICACOES EXCEDENTES. PORTANTO, A REQERENTE DEVERA COMPLEMENTAR A TAXA RELATIVA A 11 (ONZE) REIVINDICACOES EXCEDENTES.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 10 (IX), 24 E 25 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25D Requested change of name of applicant approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

B25G Requested change of headquarter approved

Owner name: MERCK SHARP AND DOHME CORP. (US)