BR9713570A - Formulações e formas polimórficas de desferrioxamina e a sua preparação. - Google Patents
Formulações e formas polimórficas de desferrioxamina e a sua preparação.Info
- Publication number
- BR9713570A BR9713570A BR9713570-4A BR9713570A BR9713570A BR 9713570 A BR9713570 A BR 9713570A BR 9713570 A BR9713570 A BR 9713570A BR 9713570 A BR9713570 A BR 9713570A
- Authority
- BR
- Brazil
- Prior art keywords
- desferrioxamine
- preparation
- forms
- formulations
- salt
- Prior art date
Links
- UBQYURCVBFRUQT-UHFFFAOYSA-N N-benzoyl-Ferrioxamine B Chemical compound CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN UBQYURCVBFRUQT-UHFFFAOYSA-N 0.000 title abstract 4
- 229960000958 deferoxamine Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- DIOQZVSQGTUSAI-NJFSPNSNSA-N decane Chemical class CCCCCCCCC[14CH3] DIOQZVSQGTUSAI-NJFSPNSNSA-N 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Patente de Invenção:<B>"FORMULAçõES E FORMAS POLIMóRFICAS DE DESFERRIOXAMINA E A SUA PREPARAçãO"<D>. Uma composição parenteralmente injetável que compreende partículas de um sal de desferrioxamina-B de um ácido sulfónico alifático tendo pelo menos 8 átomos de carbono em um óleo parenteralmente administrável. Novas modificações cristalinas de sal decano sulfónico de desferrioxamina são proporcionadas, e é mostrada uma forma de cristal com notável estabilidade.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH302496 | 1996-12-10 | ||
| GBGB9625878.5A GB9625878D0 (en) | 1996-12-12 | 1996-12-12 | Compositions |
| PCT/EP1997/006849 WO1998025887A2 (en) | 1996-12-10 | 1997-12-08 | Formulations and polymorphic forms of desferrioxamine and the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9713570A true BR9713570A (pt) | 2000-03-14 |
Family
ID=25691970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9713570-4A BR9713570A (pt) | 1996-12-10 | 1997-12-08 | Formulações e formas polimórficas de desferrioxamina e a sua preparação. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0944586A2 (pt) |
| KR (1) | KR20000069376A (pt) |
| CN (1) | CN1239946A (pt) |
| AR (1) | AR009655A1 (pt) |
| AU (1) | AU5983998A (pt) |
| BR (1) | BR9713570A (pt) |
| CA (1) | CA2274761A1 (pt) |
| CO (1) | CO4910160A1 (pt) |
| CZ (1) | CZ204499A3 (pt) |
| ID (1) | ID22388A (pt) |
| IL (1) | IL130203A0 (pt) |
| PE (1) | PE27799A1 (pt) |
| PL (1) | PL334316A1 (pt) |
| TR (1) | TR199901260T2 (pt) |
| WO (1) | WO1998025887A2 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8431301A (en) * | 1999-12-23 | 2001-11-20 | Neurochem (International) Limited | Compounds and methods for modulating cerebral amyloid angiopathy |
| GB0117645D0 (en) * | 2001-07-19 | 2001-09-12 | Isis Innovation | Therapeutic stratergies for prevention and treatment of alzheimers disease |
| DE10223913A1 (de) * | 2002-05-29 | 2003-12-11 | Bayer Cropscience Ag | Verfahren zur Herstellung spezifischer Kristallmodifikationen polymorpher Substanzen |
| JP6810988B2 (ja) | 2015-10-23 | 2021-01-13 | ヴィフォール (インターナショナル) アクチェンゲゼルシャフトVifor (International) AG | 新規なフェロポーチン阻害剤 |
| JOP20180036A1 (ar) | 2017-04-18 | 2019-01-30 | Vifor Int Ag | أملاح لمثبطات فروبورتين جديدة |
| TW202102478A (zh) | 2019-04-01 | 2021-01-16 | 瑞士商威佛(國際)股份有限公司 | 新穎的鐵螯合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH438351A (de) * | 1959-09-25 | 1967-06-30 | Ciba Geigy | Verfahren zur Herstellung neuer Wuchsstoffe |
| FR1898M (fr) * | 1961-04-07 | 1963-07-08 | Ciba Geigy | Nouvelle substance utilisable en thérapeutique. |
| GB9211779D0 (en) * | 1992-06-03 | 1992-07-15 | Ciba Geigy Ag | Amine salts |
-
1997
- 1997-12-05 AR ARP970105722A patent/AR009655A1/es unknown
- 1997-12-05 PE PE1997001097A patent/PE27799A1/es not_active Application Discontinuation
- 1997-12-08 WO PCT/EP1997/006849 patent/WO1998025887A2/en not_active Ceased
- 1997-12-08 CA CA002274761A patent/CA2274761A1/en not_active Abandoned
- 1997-12-08 EP EP97954727A patent/EP0944586A2/en not_active Withdrawn
- 1997-12-08 AU AU59839/98A patent/AU5983998A/en not_active Abandoned
- 1997-12-08 BR BR9713570-4A patent/BR9713570A/pt not_active Application Discontinuation
- 1997-12-08 PL PL97334316A patent/PL334316A1/xx unknown
- 1997-12-08 TR TR1999/01260T patent/TR199901260T2/xx unknown
- 1997-12-08 ID IDW990473A patent/ID22388A/id unknown
- 1997-12-08 KR KR1019997005104A patent/KR20000069376A/ko not_active Withdrawn
- 1997-12-08 IL IL13020397A patent/IL130203A0/xx unknown
- 1997-12-08 CN CN97180523A patent/CN1239946A/zh active Pending
- 1997-12-08 CZ CZ992044A patent/CZ204499A3/cs unknown
- 1997-12-10 CO CO97072069A patent/CO4910160A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2274761A1 (en) | 1998-06-18 |
| TR199901260T2 (xx) | 1999-10-21 |
| WO1998025887A2 (en) | 1998-06-18 |
| WO1998025887A3 (en) | 1998-08-13 |
| CO4910160A1 (es) | 2000-04-24 |
| IL130203A0 (en) | 2000-06-01 |
| AR009655A1 (es) | 2000-04-26 |
| EP0944586A2 (en) | 1999-09-29 |
| PE27799A1 (es) | 1999-03-18 |
| AU5983998A (en) | 1998-07-03 |
| CZ204499A3 (cs) | 1999-09-15 |
| ID22388A (id) | 1999-10-07 |
| PL334316A1 (en) | 2000-02-14 |
| KR20000069376A (ko) | 2000-11-25 |
| CN1239946A (zh) | 1999-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |